Adverse cutaneous reaction to hydroxychloroquine in a patient with anti-SAE-1-positive dermatomyositis and a history of diffuse large B-cell lymphoma
This report highlights the utility of the myositis-specific antibody panel to guide diagnosis and management, as well as the potential for developing dermatomyositis years after a lymphoma diagnosis.PMID:38174019 | PMC:PMC10761009 | DOI:10.1080/08998280.2023.2274231 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 4, 2024 Category: Universities & Medical Training Authors: Corley Pruneda Soumya A Reddy Hannah Buckingham Michelle Tarbox Source Type: research
Adverse cutaneous reaction to hydroxychloroquine in a patient with anti-SAE-1-positive dermatomyositis and a history of diffuse large B-cell lymphoma
This report highlights the utility of the myositis-specific antibody panel to guide diagnosis and management, as well as the potential for developing dermatomyositis years after a lymphoma diagnosis.PMID:38174019 | PMC:PMC10761009 | DOI:10.1080/08998280.2023.2274231 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 4, 2024 Category: Universities & Medical Training Authors: Corley Pruneda Soumya A Reddy Hannah Buckingham Michelle Tarbox Source Type: research
Local injection of infliximab into calcinosis lesions in patients with juvenile dermatomyositis (JDM): a clinical trial
Juvenile Dermatomyositis (JDM) is a rare autoimmune disorder that primarily affects muscles and skin. One of the severe complications associated with JDM is calcinosis, and treating this condition presents sig... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - January 2, 2024 Category: Rheumatology Authors: Reza Shiari, Mitra Khalili, Vahide Zeinali, Niloufar Shashaani, Mohammad Samami and Foroughossadat Hosseini Moghaddamemami Tags: Research article Source Type: research
Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis
Anti-melanoma differentiation-associated gene five antibody positive (MDA5+) dermatomyositis (DM) is significantly associated with rapidly progressive interstitial lung disease (RP-ILD). Early detection of RP-ILD... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 2, 2024 Category: Rheumatology Authors: Yulu Qiu, Xiaoke Feng, Chang Liu, Yumeng Shi, Lingxiao Xu, Hanxiao You, Lei Wang, Chengyin Lv, Fang Wang and Wenfeng Tan Tags: Research Source Type: research
Detection of occult neoplasia in a patient with dermatomyositis using [ < sup > 18 < /sup > F]AlF-NOTA-FAPI-04 and < sup > 18 < /sup > F-FDG PET/CT imaging
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2023 Dec 28:S2253-8089(23)00099-X. doi: 10.1016/j.remnie.2023.12.004. Online ahead of print.NO ABSTRACTPMID:38159845 | DOI:10.1016/j.remnie.2023.12.004 (Source: Molecular Medicine)
Source: Molecular Medicine - December 30, 2023 Category: Molecular Biology Authors: Zhenyan Ye Yutang Yao Jun Yin Ying Kou Zhao Meng Zhuzhong Cheng Source Type: research
Advances in the diagnostics and treatment of juvenile dermatomyositis
Z Rheumatol. 2023 Dec 29. doi: 10.1007/s00393-023-01454-y. Online ahead of print.ABSTRACTJuvenile dermatomyositis (JDM) is by far the most frequent inflammatory myopathy in childhood and adolescence. It is clinically characterized by inflammatory changes of the skin and muscles but as a multisystemic disease can also affect the skeletal system, the gastrointestinal tract, lungs and heart. Intrinsic (multigenetic risk) and extrinsic factors (triggers) are involved in the pathogenesis resulting in endothelial damage, involvement of fascies, activation of the interferon system and autoimmune reactions including formation of m...
Source: Zeitschrift fur Rheumatologie - December 29, 2023 Category: Rheumatology Authors: Ingrid Georgi Mathias Georgi Johannes-Peter Haas Source Type: research
Advances in the diagnostics and treatment of juvenile dermatomyositis
Z Rheumatol. 2023 Dec 29. doi: 10.1007/s00393-023-01454-y. Online ahead of print.ABSTRACTJuvenile dermatomyositis (JDM) is by far the most frequent inflammatory myopathy in childhood and adolescence. It is clinically characterized by inflammatory changes of the skin and muscles but as a multisystemic disease can also affect the skeletal system, the gastrointestinal tract, lungs and heart. Intrinsic (multigenetic risk) and extrinsic factors (triggers) are involved in the pathogenesis resulting in endothelial damage, involvement of fascies, activation of the interferon system and autoimmune reactions including formation of m...
Source: Zeitschrift fur Rheumatologie - December 29, 2023 Category: Rheumatology Authors: Ingrid Georgi Mathias Georgi Johannes-Peter Haas Source Type: research
Advances in the diagnostics and treatment of juvenile dermatomyositis
Z Rheumatol. 2023 Dec 29. doi: 10.1007/s00393-023-01454-y. Online ahead of print.ABSTRACTJuvenile dermatomyositis (JDM) is by far the most frequent inflammatory myopathy in childhood and adolescence. It is clinically characterized by inflammatory changes of the skin and muscles but as a multisystemic disease can also affect the skeletal system, the gastrointestinal tract, lungs and heart. Intrinsic (multigenetic risk) and extrinsic factors (triggers) are involved in the pathogenesis resulting in endothelial damage, involvement of fascies, activation of the interferon system and autoimmune reactions including formation of m...
Source: Zeitschrift fur Rheumatologie - December 29, 2023 Category: Rheumatology Authors: Ingrid Georgi Mathias Georgi Johannes-Peter Haas Source Type: research
Cardiovascular comorbidities are associated with dermatomyositis: A cross-sectional study in the All of Us Research Program
This study does not address how DM treatments (e.g. systemic steroids, methotrexate) might influence CVD development in DM and further investigation is warranted. Additional limitations include using EHRs which may have diagnostic inaccuracies/omissions, lack of data on clinical features/severity/subtype, and use of a non-representative U.S. cohort. Our findings are important both for prognosis and clinical care, suggesting DM patients should be screened for CVD risk factors to potentially reduce the increased risk of cardiovascular events and CVD-related mortality in DM. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - December 29, 2023 Category: Dermatology Authors: Jill T. Shah, Keya T. Shah, Daniel R. Mazori, Avrom S. Caplan, Emily Hejazi, Michael S. Garshick, Alisa N. Femia Source Type: research
Expansion of exhausted CD8+ T cells associates with increased pulmonary fungal infection risk in anti-melanoma differentiation associated gene 5 dermatomyositis
CONCLUSIONS: CD8 T cells from patients with anti-MDA5+ DM show significant exhausted phenotype, and increased exhausted CD8 T cells were associated with high risk of pulmonary fungal infection.PMID:38153165 | DOI:10.55563/clinexprheumatol/e51d3m (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Yue-Tong Xu Zheng-Yi Cao Sang Lin Xiao-Ming Shu Xin Lu Guo-Chun Wang Qing-Lin Peng Source Type: research
Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Treatment of refractory psoriasis with dermatomyositis using upadacitinib
Clin Exp Rheumatol. 2023 Dec 27. doi: 10.55563/clinexprheumatol/ki4jbt. Online ahead of print.NO ABSTRACTPMID:38153132 | DOI:10.55563/clinexprheumatol/ki4jbt (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Zining Xu Bingyang Xu Bin Zhao Hailong Gao Shuhong Ye Jiawen Wu Source Type: research
Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Treatment of refractory psoriasis with dermatomyositis using upadacitinib
Clin Exp Rheumatol. 2023 Dec 27. doi: 10.55563/clinexprheumatol/ki4jbt. Online ahead of print.NO ABSTRACTPMID:38153132 | DOI:10.55563/clinexprheumatol/ki4jbt (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Zining Xu Bingyang Xu Bin Zhao Hailong Gao Shuhong Ye Jiawen Wu Source Type: research
Expansion of exhausted CD8+ T cells associates with increased pulmonary fungal infection risk in anti-melanoma differentiation associated gene 5 dermatomyositis
CONCLUSIONS: CD8 T cells from patients with anti-MDA5+ DM show significant exhausted phenotype, and increased exhausted CD8 T cells were associated with high risk of pulmonary fungal infection.PMID:38153165 | DOI:10.55563/clinexprheumatol/e51d3m (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Yue-Tong Xu Zheng-Yi Cao Sang Lin Xiao-Ming Shu Xin Lu Guo-Chun Wang Qing-Lin Peng Source Type: research
