Barhi date (Phoenix dactylifera) extract ameliorates hepatocellular carcinoma in male rats
Biomed Pharmacother. 2022 Dec;156:113976. doi: 10.1016/j.biopha.2022.113976. Epub 2022 Nov 7.ABSTRACTHepatocellular carcinoma (HCC) is a malignant tumor with limited treatment options. Given this fact, it may be important to develop new molecular targeted therapies from natural products, especially those which are primary sources of effective anticancer drugs with distinct mechanisms. Moreover, the complementary use of traditional herbs or fruit may increase the possibility of finding curative options for cancer. Here we explore the anticancer effects and possible molecular mechanism of Barhi date extract using an HCC rat ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 22, 2022 Category: Drugs & Pharmacology Authors: Nabila Zein Yaser Hosny Ali Elewa Mohammed K Alruwaili Michel Dewaard Mohammed Alorabi Sarah M Albogami Gaber El-Saber Batiha Mahmoud Hosny Zahran Source Type: research
Potential bioactivity of Phoenix dactylifera fruits, leaves, and seeds against prostate and pancreatic cancer cells
In conclusion, this study showed that the presence of bioactive components in the KPC different parts extracts have the significant ability to induce the apoptotic pathway that could down-regulate the proliferation of prostate (pc3) and pancreatic (panc1) cancer cells. The pathway mechanism of action was induced by the phytol molecule presented in its leaves extract.PMID:36386915 | PMC:PMC9650284 | DOI:10.3389/fnut.2022.998929 (Source: Cancer Control)
Source: Cancer Control - November 17, 2022 Category: Cancer & Oncology Authors: Hesham S Ghazzawy Mostafa M Gouda Nabil S Awad Nadi Awad Al-Harbi Mesfer M Alqahtani Maha M Abdel-Salam Mohamed A Abdein Sanad M Al-Sobeai Asmaa A Hamad Hassan M Alsberi Gamal A Gabr Dalia M Hikal Source Type: research
Valorization of date palm leaves for adsorptive remediation of 2,4-dichlorophenoxyacetic acid herbicide polluted agricultural runoff
This study valorized date palm leaf (DPL) wastes into a valuable adsorbent for remediating agricultural wastewater polluted with 2,4-Dichlorophenoxyacetic acid (2,4-DPA) herbicide. The DPL precursor was modified with H2SO4 treatment and both biomass samples were characterized by various analytical techniques. Acid treatment modified the morphology, thermal, and textural properties of the final product (TDPL) while maintaining the structure and surface chemistry intact. Simulated wastewaters containing 2,4-DPA were subsequently treated using TDPL as an adsorbent. Optimum adsorption conditions of pH 2, dosage 0.95 g/L, shaki...
Source: Environmental Pollution - November 11, 2022 Category: Environmental Health Authors: K Rambabu G Bharath Amos Daniel Avornyo A Thanigaivelan Abdul Hai Fawzi Banat Source Type: research
Valorization of date palm leaves for adsorptive remediation of 2,4-dichlorophenoxyacetic acid herbicide polluted agricultural runoff
This study valorized date palm leaf (DPL) wastes into a valuable adsorbent for remediating agricultural wastewater polluted with 2,4-Dichlorophenoxyacetic acid (2,4-DPA) herbicide. The DPL precursor was modified with H2SO4 treatment and both biomass samples were characterized by various analytical techniques. Acid treatment modified the morphology, thermal, and textural properties of the final product (TDPL) while maintaining the structure and surface chemistry intact. Simulated wastewaters containing 2,4-DPA were subsequently treated using TDPL as an adsorbent. Optimum adsorption conditions of pH 2, dosage 0.95 g/L, shaki...
Source: Environmental Pollution - November 11, 2022 Category: Environmental Health Authors: K Rambabu G Bharath Amos Daniel Avornyo A Thanigaivelan Abdul Hai Fawzi Banat Source Type: research
Phylogeny and mycotoxin profiles of pathogenic Alternaria and Curvularia species isolated from date palm in southern Tunisia
Date palm (Phoenix dactylifera L.), is a widely cultivated crop across North Africa, with about 300 thousand tons of fruits produced per year, in Tunisia. A wide range of fungal pathogens has been associated with leaf spots of date palm, Alternaria species being the most frequently reported. Symptomatic leaves of Deglet Nour variety were randomly collected in six localities in Tunisia. We used a polyphasic approach to identify 45 Alternaria and five Curvularia strains isolated from date palm, confirming their pathogenicity. Sequencing of allergen Alt-a1, glyceraldehyde-3-phosphate dehydrogenase (gpd) and calmodulin genes a...
Source: Frontiers in Microbiology - November 7, 2022 Category: Microbiology Source Type: research
The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice
This study aimed to examine the effects of administering three extracts from powdered date pits on some basic physiological parameters, plasma constituents, reproductive hormones, and testicular histology in CD1 male mice. Three groups received doses of 100 mg/kg/day of lyophilized extract, a nonpolar fraction, and a polar fraction of date pits by oral gavage for 28 consecutive days. For the control, one group was administered a 1 mL/kg concentration of distilled water. The three different extracts significantly increased the plasma testosterone level but showed no significant effect on estradiol or luteinizing hormone lev...
Source: The Scientific World Journal - November 4, 2022 Category: Science Authors: Mohammed Al Za'abi Badreldin H Ali Haytham Ali Priyadarsini Manoj Mohammed Ashique Abderrahim Nemmar Lucie Cahl íková Source Type: research
Performance and nutrigenomics modulations in response to the inclusion of biologically treated date-palm mulch and enzyme mixture in the diets of growing rabbits
In conclusion, feeding tDPM negatively impacted rabbit's performance, however, Allzyme supplementation alleviated some of those effects. Accordingly, tDPM is recommended to be included in the diets of growing rabbits along with Allzyme supplementation.PMID:36332181 | DOI:10.1080/10495398.2022.2140055 (Source: Animal Biotechnology)
Source: Animal Biotechnology - November 4, 2022 Category: Biotechnology Authors: Mostafa M Helal Osama G Sakr Mahmoud W Sadik Mohamed A Radwan Marwa S Khattab Mohamed A El-Manylawi Source Type: research
The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice
This study aimed to examine the effects of administering three extracts from powdered date pits on some basic physiological parameters, plasma constituents, reproductive hormones, and testicular histology in CD1 male mice. Three groups received doses of 100 mg/kg/day of lyophilized extract, a nonpolar fraction, and a polar fraction of date pits by oral gavage for 28 consecutive days. For the control, one group was administered a 1 mL/kg concentration of distilled water. The three different extracts significantly increased the plasma testosterone level but showed no significant effect on estradiol or luteinizing hormone lev...
Source: The Scientific World Journal - November 4, 2022 Category: Science Authors: Mohammed Al Za'abi Badreldin H Ali Haytham Ali Priyadarsini Manoj Mohammed Ashique Abderrahim Nemmar Lucie Cahl íková Source Type: research
Performance and nutrigenomics modulations in response to the inclusion of biologically treated date-palm mulch and enzyme mixture in the diets of growing rabbits
In conclusion, feeding tDPM negatively impacted rabbit's performance, however, Allzyme supplementation alleviated some of those effects. Accordingly, tDPM is recommended to be included in the diets of growing rabbits along with Allzyme supplementation.PMID:36332181 | DOI:10.1080/10495398.2022.2140055 (Source: Animal Biotechnology)
Source: Animal Biotechnology - November 4, 2022 Category: Biotechnology Authors: Mostafa M Helal Osama G Sakr Mahmoud W Sadik Mohamed A Radwan Marwa S Khattab Mohamed A El-Manylawi Source Type: research
Performance and nutrigenomics modulations in response to the inclusion of biologically treated date-palm mulch and enzyme mixture in the diets of growing rabbits
In conclusion, feeding tDPM negatively impacted rabbit's performance, however, Allzyme supplementation alleviated some of those effects. Accordingly, tDPM is recommended to be included in the diets of growing rabbits along with Allzyme supplementation.PMID:36332181 | DOI:10.1080/10495398.2022.2140055 (Source: Animal Biotechnology)
Source: Animal Biotechnology - November 4, 2022 Category: Biotechnology Authors: Mostafa M Helal Osama G Sakr Mahmoud W Sadik Mohamed A Radwan Marwa S Khattab Mohamed A El-Manylawi Source Type: research
Performance and nutrigenomics modulations in response to the inclusion of biologically treated date-palm mulch and enzyme mixture in the diets of growing rabbits
In conclusion, feeding tDPM negatively impacted rabbit's performance, however, Allzyme supplementation alleviated some of those effects. Accordingly, tDPM is recommended to be included in the diets of growing rabbits along with Allzyme supplementation.PMID:36332181 | DOI:10.1080/10495398.2022.2140055 (Source: Animal Biotechnology)
Source: Animal Biotechnology - November 4, 2022 Category: Biotechnology Authors: Mostafa M Helal Osama G Sakr Mahmoud W Sadik Mohamed A Radwan Marwa S Khattab Mohamed A El-Manylawi Source Type: research
The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice
This study aimed to examine the effects of administering three extracts from powdered date pits on some basic physiological parameters, plasma constituents, reproductive hormones, and testicular histology in CD1 male mice. Three groups received doses of 100 mg/kg/day of lyophilized extract, a nonpolar fraction, and a polar fraction of date pits by oral gavage for 28 consecutive days. For the control, one group was administered a 1 mL/kg concentration of distilled water. The three different extracts significantly increased the plasma testosterone level but showed no significant effect on estradiol or luteinizing hormone lev...
Source: The Scientific World Journal - November 4, 2022 Category: Science Authors: Mohammed Al Za'abi Badreldin H Ali Haytham Ali Priyadarsini Manoj Mohammed Ashique Abderrahim Nemmar Lucie Cahl íková Source Type: research
Chemical profile of the pits oil from the Tunisian "Alig" cultivar of Phoenix dactylifera L.: In vivo wound healing potential evaluation of a cream formulated from the extracted oil and insights from molecular docking and SAR analysis
This study showed that the test cream promoted the healing of pressure ulcers better than the placebo cream and the MEBO ® ointment. The results showed that this vegetable oil is able to improve the healing of infected wounds in rats, thus supporting its traditional use. The contribution of the main oleic, linoleic and myristic acids that can be derived from enzymatic hydrolysis to the healing activity of the whole pits oil was predicted by in silico study and the calculated pharmacokinetics parameters.PMID:36325999 | DOI:10.1002/cbdv.202200533 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - November 3, 2022 Category: Biochemistry Authors: Rihab Chhoud Mohamed Said Bagga Mohamed Ali Lassoued Salma Jlizi Abdelkader Nabili Souad Sfar Hichem Ben Jannet Hatem Majdoub Source Type: research
Chemical profile of the pits oil from the Tunisian "Alig" cultivar of Phoenix dactylifera L.: In vivo wound healing potential evaluation of a cream formulated from the extracted oil and insights from molecular docking and SAR analysis
This study showed that the test cream promoted the healing of pressure ulcers better than the placebo cream and the MEBO ® ointment. The results showed that this vegetable oil is able to improve the healing of infected wounds in rats, thus supporting its traditional use. The contribution of the main oleic, linoleic and myristic acids that can be derived from enzymatic hydrolysis to the healing activity of the whole pits oil was predicted by in silico study and the calculated pharmacokinetics parameters.PMID:36325999 | DOI:10.1002/cbdv.202200533 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - November 3, 2022 Category: Biochemistry Authors: Rihab Chhoud Mohamed Said Bagga Mohamed Ali Lassoued Salma Jlizi Abdelkader Nabili Souad Sfar Hichem Ben Jannet Hatem Majdoub Source Type: research
