Chemical profile of the pits oil from the Tunisian "Alig" cultivar of Phoenix dactylifera L.: In vivo wound healing potential evaluation of a cream formulated from the extracted oil and insights from molecular docking and SAR analysis
This study showed that the test cream promoted the healing of pressure ulcers better than the placebo cream and the MEBO ® ointment. The results showed that this vegetable oil is able to improve the healing of infected wounds in rats, thus supporting its traditional use. The contribution of the main oleic, linoleic and myristic acids that can be derived from enzymatic hydrolysis to the healing activity of the whole pits oil was predicted by in silico study and the calculated pharmacokinetics parameters.PMID:36325999 | DOI:10.1002/cbdv.202200533 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - November 3, 2022 Category: Biochemistry Authors: Rihab Chhoud Mohamed Said Bagga Mohamed Ali Lassoued Salma Jlizi Abdelkader Nabili Souad Sfar Hichem Ben Jannet Hatem Majdoub Source Type: research

Chemical profile of the pits oil from the Tunisian "Alig" cultivar of Phoenix dactylifera L.: In vivo wound healing potential evaluation of a cream formulated from the extracted oil and insights from molecular docking and SAR analysis
This study showed that the test cream promoted the healing of pressure ulcers better than the placebo cream and the MEBO ® ointment. The results showed that this vegetable oil is able to improve the healing of infected wounds in rats, thus supporting its traditional use. The contribution of the main oleic, linoleic and myristic acids that can be derived from enzymatic hydrolysis to the healing activity of the whole pits oil was predicted by in silico study and the calculated pharmacokinetics parameters.PMID:36325999 | DOI:10.1002/cbdv.202200533 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - November 3, 2022 Category: Biochemistry Authors: Rihab Chhoud Mohamed Said Bagga Mohamed Ali Lassoued Salma Jlizi Abdelkader Nabili Souad Sfar Hichem Ben Jannet Hatem Majdoub Source Type: research

Chemical profile of the pits oil from the Tunisian "Alig" cultivar of Phoenix dactylifera L.: In vivo wound healing potential evaluation of a cream formulated from the extracted oil and insights from molecular docking and SAR analysis
This study showed that the test cream promoted the healing of pressure ulcers better than the placebo cream and the MEBO ® ointment. The results showed that this vegetable oil is able to improve the healing of infected wounds in rats, thus supporting its traditional use. The contribution of the main oleic, linoleic and myristic acids that can be derived from enzymatic hydrolysis to the healing activity of the whole pits oil was predicted by in silico study and the calculated pharmacokinetics parameters.PMID:36325999 | DOI:10.1002/cbdv.202200533 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - November 3, 2022 Category: Biochemistry Authors: Rihab Chhoud Mohamed Said Bagga Mohamed Ali Lassoued Salma Jlizi Abdelkader Nabili Souad Sfar Hichem Ben Jannet Hatem Majdoub Source Type: research

Ajwa dates (Phoenix dactylifera L.) attenuate cisplatin-induced nephrotoxicity in rats via augmenting Nrf2, modulating NADPH oxidase-4 and mitigating inflammatory/apoptotic mediators
Biomed Pharmacother. 2022 Oct 12;156:113836. doi: 10.1016/j.biopha.2022.113836. Online ahead of print.ABSTRACTIn the therapy of cisplatin (CP), nephrotoxicity is a main limiting issue that associated with oxidative stress and apoptosis. According to many studies, the antioxidant and anti-inflammatory properties of Ajwa dates are very strong, due to the unique phytochemical profile. Here, we investigated the possible mitigative effects of Ajwa dates fruits extract (ADFE) vs CP-induced nephrotoxicity in rats, in addition to phytochemical profiling of its components via LC-MS/MS. Six groups were formed from forty-two male rat...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 15, 2022 Category: Drugs & Pharmacology Authors: Eman A Abdelghffar Wael A Obaid Zuhair M Mohammed Saleh Wafae Ouchari Omayma A Eldahshan Mansour Sobeh Source Type: research

Comparative study of the morphological characteristics of Phoenix dactylifera L. cultivars in Al-Madinah Al-Munawarah-Saudi Arabia
Phoenix dactylifera L. belongs to the subfamily Coryphoideae. Saudi Arabia is the third producing country of dates in the world with over a million tons of dates every year. P. dactylifera is one of the most impo... (Source: BMC Plant Biology)
Source: BMC Plant Biology - September 26, 2022 Category: Biology Authors: Meaad F. Alaida and Amal Y. Aldhebiani Tags: Research Source Type: research

Date Palm as Source of Nutraceuticals for Health Promotion: a Review
AbstractPurpose of ReviewChronic diseases are problematic to health professional specially when using drugs throughout the course of life with un-tolerated side effects. Returning to nature through using nutraceuticals might have both protective and therapeutic effects. Date palm was claimed to be a good source of such nutraceuticals or functional food ingredients. The purpose of the present review was to spot light on the different phytochemicals, phytonutrients, and remedial effects of date palm (Phoenix dactylifera L.) in a goal to be utilized in form of nutraceuticals. The possible mechanisms of action of the remedial ...
Source: Current Nutrition Reports - September 20, 2022 Category: Nutrition Source Type: research

Ameliorative effects of the phytochemicals in dates (Phoenix dactylifera) against the toxicological changes induced by fipronil in male albino rats
This study showed that fipronil-induced various health hazards in vivo, whereas date extract alleviated the said toxicological effects. However, date extract failed to reduce genotoxicity.PMID:36113622 | DOI:10.1016/j.tox.2022.153313 (Source: Toxicology)
Source: Toxicology - September 16, 2022 Category: Toxicology Authors: Hossam El Din H Abdelhafez Amr A AbdAllah Asmaa A El-Dahshan Yasser A Abd El-Baset Osama M Morsy Mohamed Bedair M Ahmed Source Type: research

Ameliorative effects of the phytochemicals in dates (Phoenix dactylifera) against the toxicological changes induced by fipronil in male albino rats
This study showed that fipronil-induced various health hazards in vivo, whereas date extract alleviated the said toxicological effects. However, date extract failed to reduce genotoxicity.PMID:36113622 | DOI:10.1016/j.tox.2022.153313 (Source: Toxicology)
Source: Toxicology - September 16, 2022 Category: Toxicology Authors: Hossam El Din H Abdelhafez Amr A AbdAllah Asmaa A El-Dahshan Yasser A Abd El-Baset Osama M Morsy Mohamed Bedair M Ahmed Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research

Methyl jasmonate induces oxidative/nitrosative stress and the accumulation of antioxidant metabolites in Phoenix dactylifera L
CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.PMID:36100779 | DOI:10.1007/s10529-022-03299-y (Source: Biotechnology Letters)
Source: Biotechnology Letters - September 13, 2022 Category: Biotechnology Authors: Amal Ben Romdhane Yassine Chtourou Haifa Sebii Emna Baklouti Ameni Nasri Riadh Drira Mohamed Maalej Noureddine Drira Alain Rival Lotfi Fki Source Type: research