Qualit ätskontrolle in der Hornhautbank mit KI: Vergleich des neuen Deep-Learning-basierten Ansatzes mit der konventionellen Endothelzelldichtenbestimmung durch das Rhine-Tec System
This study aims to compare this new method with the conventional Rhine-Tec system. 9,375 archived phase-contrast microscopic images of consecutive grafts from the Lions Eye Bank were evaluated with the deep learning method and compared with the corresponding archived analyses of the Rhine-Tec system. Specifically, comparisons of means, Bland-Altman and correlation analyses were performed. Comparable results were obtained for both methods. The mean difference between the Rhine-Tec system and the deep learning method was only -23 cells/mm2 (95% confidence interval -29 to -17). There was a statistically significant positive c...
Source: Klinische Monatsblatter fur Augenheilkunde - April 4, 2024 Category: Opthalmology Authors: Michelle Dreesbach Daniel B öhringer Paola Kammrath Betancor Mateusz Glegola Philip Christian Maier Thomas Reinhard Sonja Heinzelmann Source Type: research

Descemet Membrane Endothelial Keratoplasty (DMEK) Anesthesia Analysis
CONCLUSION: DMEK under topical anesthesia is feasible and shows comparable final visual outcomes but should be limited to selected cooperative patients and performed by experienced surgeons due to the potential for increased intraoperative challenges.PMID:38574678 | DOI:10.1055/a-2268-9295 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 4, 2024 Category: Opthalmology Authors: Christoph Andres Andr é Maurice Trouvain Peter Szurman Berthold Seitz Fabian Norbert Fries Annekatrin Rickmann Source Type: research

Chemical, Physical, and Biological Corneal Decellularization Methods: A Review of Literature
This article discusses different methods of corneal decellularization based on the current literature. We searched PubMed.gov for articles from January 2009 to December 2023 using the following keywords: corneal decellularization, decellularization methods, and corneal transplantation. Although several methods of decellularization of corneal tissue have been reported, a universal standardised protocol of corneal decellularization has not yet been introduced. In general, a combination of decellularization methods has been used for efficient decellularization while preserving the optimal properties of the corneal tissue.PMID...
Source: Journal of Ophthalmology - April 3, 2024 Category: Opthalmology Authors: Alexandra Proch ázková Martina Pol áchová Jakub D ítě Magdal éna Netuková Pavel Studen ý Source Type: research