The Healing Process and Functional Recovery of Neuroretina after Idiopathic Macular Hole Surgery without Internal Limiting Membrane Reversal Tamponade.
Conclusion: Full-thickness IMHs could achieve anatomic closure 3 to 5 days after surgery with first-step inner retina tissue bridging. Otherwise, they were not able to achieve hole closure and opened to larger holes about 2 weeks postoperatively. Macular hole diameter was an important factor affecting the healing of the holes. The delayed restoration of fovea detachment and ellipsoid area deficiency were responsible for poor vision outcomes after surgery. PMID: 32454986 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Results of Ranibizumab Treatment of the Myopic Choroidal Neovascular Membrane according to the Axial Length of the Eye.
Authors: Stepanov A, Pencak M, Nemcansky J, Matuskova V, Stredova M, Beran D, Studnicka J Abstract Aim: A retrospective evaluation of the results of treatment of myopic choroidal neovascularization (mCNV) with intravitreal injections of ranibizumab in a pro re nata (PRN) regimen in three groups of patients distributed according to axial length. Methods: The paper presents a retrospective multicenter study carried out with the cooperation of several Departments of Ophthalmology in the Czech Republic. The study included 60 eyes of 60 patients suffering from mCNV, divided according to axial length into three group...
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Peripheral Refraction in Myopic Children with and without Atropine Usage.
Conclusion: Significant differences in relative peripheral refraction were found between the atropine group and its controls. The findings suggested that the eyes that received atropine may have a less prolate shape and thus explain why using atropine is effective in controlling myopia progression. PMID: 32454988 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Subfoveal Choroidal Thickness in Myopia: An OCT-Based Study in Young Chinese Patients.
Authors: Xiong F, Tu J, Mao T, Yu L, Lin N, Liao H Abstract Myopia is a common cause of visual impairment worldwide. Choroidal thickness (ChT) reflects the characteristic changes in myopic children and may be used as an important index of myopia. The purpose of this study was to investigate ChT and its distribution across the posterior pole in young myopic Chinese patients using enhanced depth imaging optical coherence tomography (EDI-OCT) and to explore the factors associated with it. A total of 402 myopic Chinese patients aged 6-16 years who underwent complete ophthalmic examinations, including those for axial le...
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Multimodal Imaging Features of Bilateral Choroidal Ganglioneuroma.
Conclusion: Choroidal ganglioneuroma is rare. To our knowledge, no bilateral cases have been described in the literature. Major clinical features include a rapid increase in axial length, diffuse choroidal thickening, hyper-reflectivity in the choroid on optical coherence tomography, and loss of choroidal vasculature on ICGA. The current report provides multimodal imaging of choroidal ganglioneuroma for the first time and can be valuable for early diagnosis. PMID: 32454990 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Preoperative Steroid Use in Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment after 23-Gauge Vitrectomy.
Conclusions: Preoperative steroid use does not improve retinal reattachment and visual acuity in patients with RRDCD after 23-gauge PPV. Preoperative measurement of the cyclodialysis angle with ultrasound biomicroscopy may be useful for predicting clinical outcomes. PMID: 32454991 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Pseudodominant Nanophthalmos in a Roma Family Caused by a Novel PRSS56 Variant.
Conclusions: Herein, we report the first occurrence of nanophthalmos in the Roma population. We have identified pseudodominant inheritance for this phenotype caused by a novel variant in PRSS56, representing a possible founder effect. Despite advances in genetic technologies such as exome sequencing, careful phenotype evaluation in patients from an isolated population, along with an awareness of population-specific founder effects, is necessary to ensure that accurate molecular diagnoses are made. PMID: 32454992 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Microcornea and Thickened Lens in Angle Closure following Nonsurgical Treatment of Retinopathy of Prematurity.
Authors: Chang TC, Tran KD, Cernichiaro-Espinosa LA, Leung EH, Grajewski AL, Hodapp EA, Abou Shousha MF, Berrocal AM Abstract Purpose: To characterize the clinical features in young patients with angle closure and to determine the characteristics associated with acquired anterior segment abnormality following retinopathy of prematurity (ROP) treatment. Methods: We performed two retrospective case-control series. In the first series, we identified consecutive young angle closure patients without prior surgeries, with and without a history of ROP treatment; in the second series we identified consecutive patients ...
Source: Journal of Ophthalmology - May 28, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery.
Authors: Wei P, Cheng GP, Zhang J, Ng AL, Chan TC, Jhanji V, Wang Y Abstract Purpose: To investigate the variations of corneal volume (CV) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and analyze the influences of biomechanical properties on the changes of refraction and CV. Methods: Ninety-seven eyes of 97 patients undergoing SMILE and FS-LASIK were included in this retrospective study. CV was measured with Scheimpflug-based corneal topography at preoperatively and at day 1, week 1, and months 1 and 3 postoperatively. CV measured withi...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Female Gender Remains a Significant Barrier to Access Cataract Surgery in South Asia: A Systematic Review and Meta-Analysis.
Authors: Ye Q, Chen Y, Yan W, Wang W, Zhong J, Tang C, Müller A, Qiu B Abstract Purpose: To determine whether the female gender is a barrier for the access to cataract surgery services in South Asia in the last two decades. Methods: Eligible cross-sectional studies were identified via computer searches and reviewing the reference lists of the obtained articles. The cataract surgical coverage (CSC) by sex based on person and eyes at visual acuity
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Management of Cataract in Patients with Irregular Astigmatism with Regular Central Component by Phacoemulsification Combined with Toric Intraocular Lens Implantation.
Authors: Gao Y, Ye Z, Chen W, Li J, Yan X, Li Z Abstract Purpose: To evaluate visual acuity (VA) and refractive status in patients with cataract and irregular astigmatism with a regular central component after phacoemulsification with implantation of a toric intraocular lens (IOL). Methods: Patients with cataract associated with irregular astigmatism with a regular central component were enrolled. All patients underwent phacoemulsification and toric IOL implantation. Postoperative visual acuity, residual astigmatism, toric IOL rotation, higher-order aberration, and objective and subjective visual quality were m...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Functional Outcomes and OCT-Biomarkers after Intravitreal Dexamethasone Implant for Postoperative Cystoid Macular Edema in Vitrectomized Eyes.
Conclusion: The efficacy of the treatment of PCME in vitrectomized eyes seems to be affected by baseline BCVA, the absence of SRF, and the indication for surgery. Naïve status appears not to play any significant role in the prediction of BCVA. This trial is registered with DRKS00018955. PMID: 32411428 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Quantification of Microvascular Density of the Optic Nerve Head in Diabetic Retinopathy Using Optical Coherence Tomographic Angiography.
Authors: Huang J, Zheng B, Lu Y, Gu X, Dai H, Chen T Abstract Aims: To quantify the capillary density of the optic nerve head in healthy control eyes and different stages of diabetic retinopathy (DR) eyes and identify the parameters to detect eyes with or without DR using optical coherence tomographic angiography (OCTA). Methods: In this cross-sectional study, 211 eyes of 121 participants with type 2 diabetes with different stages of DR or without DR and 73 eyes of 38 healthy age-matched controls were imaged by OCTA. Radial peripapillary capillary (RPC) plexus density and retinal nerve fiber layer (RNFL) thickn...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Microbiological Isolates and Antibiotic Susceptibilities in Cases of Posttraumatic Endophthalmitis: A 15-Year Review.
The objective of this study was to evaluate the microbiological spectrum and antibiotic susceptibilities of isolates in posttraumatic endophthalmitis over a 15-year period. Methods: A retrospective study of 3,163 posttraumatic endophthalmitis cases was conducted between July 2004 and July 2019. The outcome measures included the microbiological spectrum and antibiotic susceptibilities. Chi-squared tests were conducted to detect trends in changes in antibiotic sensitivity over the 15-year period. P values of
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Changes in Macular Perfusion Detected by Optical Coherence Tomography Angiography following 3 Intravitreal Monthly Bevacizumab Injections for Diabetic Macular Edema in the IMPACT Study.
This study was a prospective noncomparative interventional case series. Treatment naïve patients with DME underwent full ophthalmological examination and SD-OCTA scanning at baseline and after 3 intravitreal bevacizumab injections. Both the 6 × 6 and 3 × 3 mm macular scan protocols were used. Pretreatment and posttreatment OCTA images were automatically aligned using a commercially available retina alignment software (i2k Align Retina software); then the fractal dimension (FD), vascular density (VD), and skeleton VD changes were obtained at the full retinal thickness (Ful...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Blended Vision Achieved by Combining High and Low Addition Power Diffractive Intraocular Lenses with Micromonovision: A Clinical Outcome.
Conclusion: MMBV provided a better intermediate VA, contrast sensitivity, and low-contrast VA than bilateral implantation of the +4 D add MIOL, while preserving comparable near and distance vision. PMID: 32411432 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Elevated Plasma Level of 8-Hydroxy-2'-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma.
Conclusion: The study shows that there is a significant association between elevated plasma 8-OHdG and POAG, supporting the role of systemic oxidative stress-induced DNA damage in POAG pathogenesis. However, with a high rate of false-positivity, plasma 8-OHdG may lack the ability to serve as a potential biomarker in POAG. Further studies in a much larger cohort are needed to confirm these findings. PMID: 32411433 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Multimodal Retinal Image Analysis via Deep Learning for the Diagnosis of Intermediate Dry Age-Related Macular Degeneration: A Feasibility Study.
Conclusions: Here we demonstrate that superior diagnostic accuracy can be achieved when deep learning is combined with multimodal image analysis. PMID: 32411434 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Assessing the Performance of Daily Intake of a Homotaurine, Carnosine, Forskolin, Vitamin B2, Vitamin B6, and Magnesium Based Food Supplement for the Maintenance of Visual Function in Patients with Primary Open Angle Glaucoma.
The objective of this study was to assess the effect of daily intake of a homotaurine, carnosine, forskolin, vitamins B1, B2, and B6, folic acid, and magnesium based supplement (GANGLIOLIFE®) on the progression rates of the visual field in patients with progressive POAG despite good tonometric compensation and to assess the most suitable dosage. Methods: This is a monocentric nonrandomized experimental clinical study. Patients with mean deviation (MD) ranging from -2 dB to -15 dB with MD progression ≥1 dB in the previous year and IOP values of ≤18 mm Hg were included. All the patie...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Characteristics of Intraocular Lens Dislocation in Chinese Han Populations.
Authors: Fan Q, Han X, Zhu X, Cai L, Qiu X, Lu Y, Yang J Abstract Purpose: To investigate the clinical characteristics of patients with intraocular lens (IOL) dislocation after IOL implantation in Chinese Han populations. Methods: The medical records of patients with IOL dislocation were retrospectively reviewed from January 2007 to December 2017, and a total of 312 patients (male: 231, female: 97) (328 eyes) were included in this study. The axial length (AL), IOL power, and the time interval between cataract surgery and IOL dislocation as well as the ocular conditions associated with IOL dislocation were recor...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Multivariate Regression Analysis to Predict Postoperative Refractive Astigmatism in Cataract Surgery.
Authors: Kawahara A, Sato T, Hayashi K Abstract Purpose: To assess the correlation between postoperative refractive astigmatism and preoperative parameters in cataract surgery. Methods: Left eyes of 100 consecutive patients scheduled for cataract surgery with a 2.4 mm clear corneal incision were examined prospectively. Refractive astigmatism was measured using an autokerato/refractometer. Corneal astigmatism of the total cornea was calculated using a Scheimpflug camera. The vertical/horizontal component (J0) and oblique component (J45) of refractive and total corneal astigmatism were determined using pow...
Source: Journal of Ophthalmology - May 17, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Application of Artificial Neural Networks and Logistic Regression in the Evaluation of Risk for Dry Eye after Vitrectomy.
In conclusion, both LR and ANN models may be used to accurately predict the occurrence of DED after vitrectomy. PMID: 32377409 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Cross-Knotted Suture Basket Technique for Large Nonmagnetic Intraocular Foreign Body Removal.
Conclusion: The suture basket technique provides an accessible, safe, and effective alternative in large nonmagnetic IOFB removal. It can be adapted and interchangedand also worth's further clinical investigations. PMID: 32377410 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Visual Field and Balance Function Alterations in Patients Who Underwent Dermatochalasis Surgery.
Authors: Akidan M, Turgut Coban D, Erol MK, Balci U Abstract Purpose: To compare perioperative visual field (VF), balance functions (BF), and changes in the other ocular parameters in patients undergoing upper eyelid dermatochalasis (DC) surgery. Methods: One hundred and fifty-eight eyes of 79 patients who underwent DC surgery were included in the study. The VF, BF, intraocular pressure (IOP), pachymetry (PM), macular, and optic nerve measurements were recorded. Measurements were repeated at postoperative month 1. The preoperative and postoperative ocular measurements and the balance data were compared. Res...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Efficacy of 0.5% Levofloxacin and 5.0% Povidone-Iodine Eyedrops in Reducing Conjunctival Bacterial Flora: Metagenomic Analysis.
In conclusion, the metagenomic analysis using high-throughput sequencing provides a scientific way for evaluating the effectiveness of a disinfection method from the perspective of analyzing the composition and diversity of the conjunctival microbiome. Despite the use of preoperative antisepsis regimens, the ocular surface of patients receiving cataract surgery could not be rendered completely aseptic, indicating that more strict disinfection methods need to be adopted to reduce the risk for anterior chamber contamination and endophthalmitis after cataract surgery. PMID: 32377412 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey I κBα-siRNA.
Conclusion: It proves that the siRNA targeting the GCACTTAGCCTCTATCCAT of IκBα gene is the valid sequence to suppress cynomolgus monkey IκBα expression of CM cells and TM cells by RNAi. 10 nM is the optimal transfection concentration. PMID: 32377413 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Visual and Refractive Outcomes of Cataract Surgeries Performed in One Year in a Private Practice Setting: Review of 2714 Procedures.
Conclusions: The visual and refractive outcomes of cataract surgery in a private practice setting were excellent, well over the benchmarks set by the ESCRS. The safety profile was also within expected standards. This study provides information for ophthalmologists in private practice on expected outcomes. PMID: 32377414 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Manifestations, Diagnosis, and Surgery of Inferior Oblique Muscle Ectopia.
Conclusions: IO-E is a rare congenital dysplasia variation of the extraocular muscle, which could appear as inferior oblique overaction. It is difficult to diagnose before surgery, and weakening the overactive ectopic inferior oblique was required for better prognosis if this condition was confirmed during surgery. PMID: 32377415 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Knowledge towards Strabismus and Associated Factors among Adults in Gondar Town, Northwest Ethiopia.
Conclusion: Almost half of the participants had good knowledge. Occupation and monthly income had a significant association with knowledge about strabismus. Since the source of information (TV/radio and Internet) was extremely important for the reliability and the level of knowledge, it is better to have sufficient media coverage. PMID: 32377416 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Intravitreal Injections in Arc Sterile Setting: Safety Profile after More Than 10,000 Treatments.
Conclusions: Arc Sterile seems to be a safe setting in which IVIs can be carried out, regarding infective risk, and it is easy to set up compared to operation theatre and useful to improve intravitreal injections governance. PMID: 32377417 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Small Incision Lenticule Extraction (SMILE) for Moderate and High Myopia: Seven-Year Outcomes of Refraction, Corneal Tomography, and Wavefront Aberrations.
Authors: Xia F, Shen Y, Han T, Zhao J, Xu H, Zhou X Abstract Purpose: To investigate the long-term outcomes of refraction, corneal tomography, and wavefront aberrations after small incision lenticule extraction (SMILE) for moderate and high myopia. Methods: Prospective, nonconsecutive case series. A total of 26 patients (26 eyes) who underwent SMILE from May 2010 to March 2013 at the Fudan University Eye and ENT Hospital (Shanghai, China) were enrolled. The periods of follow-up were 1 month, 1 year, 5 years, and 7 years after surgery. The routine eye examinations included uncorrected distance visual acuity (UDV...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy.
This study aimed to investigate the expression of collagen (types I, III, and V), heat shock protein 47 (HSP47), matrix metalloproteinase-2 (MMP-2), and tissue inhibitors of metalloproteinase-1 (TIMP-1) in the retrobulbar adipose tissues of patients with thyroid-associated orbitopathy (TAO). Materials and Methods: The retrobulbar adipose tissues were collected from 4 TAO patients undergoing orbital decompression and 4 ocular enucleation patients with atrophic eyeball caused by ocular trauma between May 2019 and September 2019. Masson staining was performed to analyze the differences in collagen expression and degree of...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Difference in Repeatability of Automated Superficial Retinal Vessel Density according to the Measurement Area Using OCT Angiography.
Authors: Lim HB, Kang TS, Won YK, Kim JY Abstract Purpose: To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods: A total of 127 normal eyes from 127 healthy subjects were included. Macular angiography images were acquired from all subjects using the Zeiss Cirrus 5000 with AngioPlex™ OCTA software. Scans of 3 × 3 mm and 6 × 6 mm were each performed twice in a randomly arranged se...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Characteristics and Visual Outcomes of Patients Hospitalized for Ocular Trauma in Shandong Province, China.
Authors: Duan F, Chen X, Zhang S, Qi X, Shi W, Gao H Abstract Purpose: To analyze the clinical characteristics and visual prognoses of patients with ocular trauma treated in Shandong Eye Hospital. Methods: The inpatient data of patients with eye injuries hospitalized in our institution from January 2014 to December 2018 were retrospectively reviewed, including demographic information, types of trauma, causes of injury, treatment, and initial and final visual acuities. Results: A total of 1,425 patients (1,622 eyes), aged 39.5 ± 18.5 years, were included. The ratio of male to female was ...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Proportion of Ophthalmic Self-Medication and Associated Factors among Adult Ophthalmic Patients Attending Borumeda Hospital, Dessie, Northeast Ethiopia.
Conclusion and Recommendations. The proportion of ophthalmic self-medication was high, which needs stakeholders' attention. The policymakers and regulatory body better to scale-up health insurance coverage, nearby accessible eye care services, improve knowledge of patients regarding the effect of ophthalmic self-medication, and proper disposal of leftover eye medication from the house. It is better to take regulatory actions on those who dispense ophthalmic medications without prescription. PMID: 32377422 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparative Analysis of Visual Performance and Optical Quality with a Rotationally Asymmetric Multifocal Intraocular Lens and an Apodized Diffractive Multifocal Intraocular Lens.
Authors: Wang X, Tu H, Wang Y Abstract Purpose: To compare the short-term visual outcomes and intraocular optical performance of a rotationally asymmetric multifocal intraocular lens (MIOL) (SBL-3, Lenstec, Inc., Christ Church, Barbados) and an apodized diffractive MIOL (the Acrysof IQ ResTOR SN6AD1, Alcon Laboratories, Inc., Fort Worth, Texas, United States). Methods: A prospective, comparative, nonrandomized, and single-center study. Sixty-eight age-related cataract patients (81 eyes) after phacoemulsification cataract surgery and in-the-bag MIOL implantation were enrolled. Thirty-eight eyes received SBL-3, a...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Effect of Phacoemulsification on Anterior Chamber Angle in Eyes with Medically Uncontrolled Filtered Primary Angle-Closure Glaucoma.
Authors: Zuo C, Long B, Guo X, Chen L, Liu X Abstract Purpose: To evaluate the effect of phacoemulsification and intraocular lens (IOLs) implantation in eyes with medically uncontrolled primary angle-closure glaucoma (PACG) previously treated with trabeculectomy and to quantify the anatomical changes in the anterior chamber angle by ultrasound biomicroscopy (UBM). Methods: Forty-four eyes of 37 consecutive patients with medically uncontrolled PACG coexisting cataracts with a surgical history of trabeculectomy were included in this study. Each patient underwent phacoemulsification and IOL implantation. Indentati...
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Adverse Impact of Glaucoma on Psychological Function and Daily Physical Activity.
This study included 50 glaucoma patients and 50 healthy control subjects. Sociodemographic and clinical data were collected from all subjects. A Chinese version of the NEI VFQ-25 was used to evaluate the quality of life. Objective physical activity was assessed by wearing an accelerometer for 7 consecutive days. Results: No significant difference was found in sociodemographic data between the two groups (all p
Source: Journal of Ophthalmology - May 8, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Rotational Stability of a New Posterior Chamber Toric Phakic Intraocular Lens.
Conclusion: The pIOL appears to effectively reduce subjective manifest astigmatism and provide good visual acuity. Its position was found to be stable throughout the follow-up. PMID: 32351717 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Altered Macular Vasculature in Migraine Patients without Aura: Is It Associated with Ocular Vasculature and White Matter Hyperintensities?
Conclusion: We suggest that for not only migraine with aura but also migraine without aura, neurovascular structures play an important role in pathogenesis, and novel studies are warranted to elucidate the alterations in these and determine the significance of WMHs in these patient groups. PMID: 32351718 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Therapeutic Effect of Intense Pulsed Light (IPL) Combined with Meibomian Gland Expression (MGX) on Meibomian Gland Dysfunction (MGD).
This study was a prospective interventional study. A total of 53 patients were included in the study and received a series of three treatments at an interval of 3-4 weeks. Follow-up examinations were completed 4 weeks after the last treatment. The Ocular Surface Disease Index (OSDI) questionnaire, tear meniscus height (TMH), tear break-up time (TBUT), slit-lamp examinations, and in vivo confocal microscopy (IVCM) were recorded before and after treatment. Additionally, an artificial intelligence automated software program was applied in our study for corneal nerve analysis. Results: The OSDI score was significantly redu...
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Parent Knowledge of Screening and Genetic Testing in Retinoblastoma.
Conclusion: Overall parent knowledge about retinoblastoma screening and genetic testing was moderate. Higher education was associated with greater parent knowledge. Future studies should validate our findings in other populations, especially in those with different cultural background and healthcare systems. PMID: 32351720 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Modulation of Laser Refractive Surgery on Sensory Eye Dominance of Anisometropia.
Authors: Liu H, Chen Q, Lan F, Luo Y, Lin E, Luo W, Kong M, Wang J, Zhang F Abstract Purpose: To evaluate the effect of laser refractive surgery on sensory eye dominance of anisometropia. Methods: A total of 156 subjects with nonanisometropic myopia and 70 subjects with anisometropic myopia were enrolled in the first part of the study. The dichoptic motion coherence threshold technique was applied to collect the normal dataset and distribution of sensory eye dominance. The second part of the study included 40 subjects with nonanisometropic myopia and 40 subjects with anisometropic myopia who received the femtos...
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Real-Life Management of Diabetic Macular Edema with Dexamethasone Intravitreal Implant: A Retrospective Analysis of Long-Term Clinical Outcomes.
Conclusions: With fewer than 3 injections per patient over a 3-year period, DEX implant was able to improve anatomic outcomes in DME patients. Only pseudophakic eyes showed also a long lasting functional benefit at 36 months. PMID: 32351722 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Trends in the Retinal Nerve Fiber Layer Thickness Changes with Different Degrees of Visual Field Defects.
Conclusion: The rate of RNFL thinning is linear; RNFL thinning is the fastest in individuals with mild baseline VF defects, followed by those with moderate baseline VF defects. In individuals with severe VF defects, changes in the RNFL thickness do not appropriately reflect the progression of the disease. The clinical trial is registered with ChiCTR2000028975. PMID: 32351723 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Long-Term Outcomes of Allogeneic Ocular Surface Reconstruction: Keratolimbal Allograft (KLAL) Followed by Penetrating Keratoplasty (PK).
Conclusions: Successful KLAL carries a high risk of subsequent PK failure. Visual function remains the second aim of treatment; the primary one is to stabilize the surface. PMID: 32351724 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Influence of Decentration on Higher-Order Aberrations in Artisan Aphakic Intraocular Lens Implantation Eyes.
Conclusions: The position of Artisan IOLs showed slight decentration and the amounts of decentration were not large enough to influence higher-order aberrations. PMID: 32351725 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Application of Femtosecond Laser in Anterior Segment Surgery.
Authors: Han SB, Liu YC, Mohamed-Noriega K, Mehta JS Abstract Femtosecond laser (FSL) is a near-infrared laser that can create reliable and reproducible tissue cutting with minimal damage to adjacent tissue. As the laser can also create incisions with various orientations, depths, and shapes, it is expected to be a useful tool for anterior segment surgery, such as cornea, refractive, and cataract surgery. In this review, the authors will introduce the application of FSL in various anterior segment surgeries and discuss the results of studies regarding the efficacy and safety of FSL in cornea, refractive, and catara...
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure.
Conclusions: Patients who underwent phaco/IOL had better IOP control, improved vision, deeper ACD, and wider angle and required less antiglaucoma medications than those who underwent LPI alone. Performing phaco/IOL weeks to months after the initial LPI did not appear to adversely affect outcomes compared with those of early phaco/IOL. PMID: 32351727 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Hydrogen Sulfide and β-Synuclein Are Involved and Interlinked in the Aging Glaucomatous Retina.
Conclusion: The present study indicates a strong link between ageing and SNCB regulation. In young animals SNCB is downregulated going along with less RGC loss. Furthermore, increasing endogenous H2S is effective to downregulate SNCB and is neuroprotective against acute IOP elevation. PMID: 32351728 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 1, 2020 Category: Opthalmology Tags: J Ophthalmol Source Type: research