Clinical and Imaging Characteristics of Metastatic Orbital Tumours in North China
CONCLUSIONS: In North China, the most common primary cancer that metastasizes to the orbit is breast cancer, followed by gastrointestinal tract carcinoma and lung cancer. The increasing trend of orbital gastrointestinal tract metastases in North China in recent years is noteworthy. The survival rate of patients with orbital metastasis of neuroblastoma is low.PMID:38370869 | PMC:PMC10874289 | DOI:10.1155/2024/3394425 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2024 Category: Opthalmology Authors: Yun Zhao Shasha Yu Mengxia Mu Jiagen Li Hongxun Li Hong Zhao Source Type: research

Efficacy of 2% Hydroxypropyl Methylcellulose and Bandage Contact Lens for the Management of Dry Eye Disease after Cataract Surgery
CONCLUSIONS: The application of 2% HPMC in cataract surgery has a certain effect on managing dry eye after cataract surgery. Although the use of BCLs after cataract surgery has some benefits, it may cause mild ocular surface inflammation. Nevertheless, using 2% HPMC with BCLs in the perioperative phase of cataract surgery can alleviate the subjective discomfort of patients and can safely and effectively replace eye patch after cataract surgery.PMID:38333732 | PMC:PMC10853018 | DOI:10.1155/2024/8415425 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 9, 2024 Category: Opthalmology Authors: Tianyao Zhao Xiaodan Jiang Ran Hao Yi Ding Dalan Jing Xuemin Li Source Type: research

Congenital Malformations of the Eye: A Pictorial Review and Clinico-Radiological Correlations
J Ophthalmol. 2024 Jan 30;2024:5993083. doi: 10.1155/2024/5993083. eCollection 2024.ABSTRACTCongenital malformations of the eye represent a wide and heterogeneous spectrum of abnormalities that may be part of a complex syndrome or be isolated. Ocular malformation severity depends on the timing of the causative event during eye formation, ranging from the complete absence of the eye if injury occurs during the first weeks of gestation, to subtle abnormalities if the cause occurs later on. Knowledge of ocular malformations is crucial to performing a tailored imaging protocol and correctly reporting imaging findings. Together...
Source: Journal of Ophthalmology - February 7, 2024 Category: Opthalmology Authors: Alessia Guarnera Paola Valente Luca Pasquini Giulia Moltoni Francesco Randisi Chiara Carducci Alessia Carboni Giulia Lucignani Antonio Napolitano Antonino Romanzo Daniela Longo Carlo Gandolfo Maria Camilla Rossi-Espagnet Source Type: research

The Effect of a Loading Dose Regimen in the Switch to Brolucizumab for Patients with Aflibercept-Resistant nAMD
CONCLUSION: Switching to brolucizumab from aflibercept for eyes with nAMD with resistance to bimonthly injections of aflibercept is a valuable treatment option with and without the loading regimen. This trial is registered with UMIN000023676.PMID:38322501 | PMC:PMC10846919 | DOI:10.1155/2024/3673930 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 7, 2024 Category: Opthalmology Authors: Hiroyuki Kamao Erika Mitsui Yuto Date Katsutoshi Goto Kenichi Mizukawa Atsushi Miki Source Type: research

Long-Term Surgical Outcomes of Glaucoma Drainage Implants in Eyes with Preoperative Intraocular Pressure Less than 19  mmHg
CONCLUSION: In patients with baseline IOP ≤18 mmHg who had GDI surgery, though the change in IOP was not statistically significant, the number of medications dropped and visual field progression slowed in a subset of patients with adequate perimetric data. Due to a relatively high rate of complications and limited effectiveness in lowering IOP, GDI should be cautiously used in these eyes.PMID:38304290 | PMC:PMC10830923 | DOI:10.1155/2024/6624021 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 2, 2024 Category: Opthalmology Authors: Shahin Hallaj Jae-Chiang Wong Lauren E Hock Natasha Nayak Kolomeyer Aakriti G Shukla Michael J Pro Marlene R Moster Jonathan S Myers Reza Razeghinejad Daniel Lee Source Type: research

miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF- < em > κ < /em > B Signaling Pathway
CONCLUSION: miR-26a-5p inhibits oxidative stress and inflammation in DR progression by targeting USP14 and inactivating the NF-κB signaling pathway.PMID:38282961 | PMC:PMC10817816 | DOI:10.1155/2024/1470898 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - January 29, 2024 Category: Opthalmology Authors: Jie Bian Weizhong Ge Zhengmei Jiang Source Type: research