The Effects of Scleral Collagen Cross-Linking Using Glyceraldehyde on the Progression of Form-Deprived Myopia in Guinea Pigs.
Authors: Chu Y, Cheng Z, Liu J, Wang Y, Guo H, Han Q Abstract To investigate the effects of collagen cross-linking using glyceraldehyde on the biomechanical properties of the sclera and the axial elongation of form-deprived myopia in the guinea pig. Thirty-six guinea pigs were randomly assigned to four groups: FDM (form-deprived myopia); FDMG (form-deprived myopia treated with glyceraldehyde); FDMS (form-deprived myopia treated with 0.9% isotonic sodium chloride); and normal control (free of form-deprivation). FDM was achieved in the right eye using a latex facemask. The right eye in FDMG was treated with a posteri...
Source: Journal of Ophthalmology - August 10, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis.
This study investigated the expression of thymic stromal lymphopoiet in TSLP and its downstream molecules in conjunctival scrappings and tear. Methods. This cross-sectional study compares patients with vernal keratoconjunctivitis (VKC), seasonal allergic conjunctivitis (SAC), and perennial allergic conjunctivitis (PAC) with normal controls. There are 80 people recorded in Shanxi Eye Hospital. Increasingly, 20 are with VKC, 20 are with SAC, 20 are with PAC, and the remaining 20 are normal controls. Conjunctiva were harvested for total RNA extraction and gene expression by real-time polymerase chain reaction. Epithelial cell...
Source: Journal of Ophthalmology - August 10, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

An Update on the Ophthalmologic Features in the Phakomatoses.
Authors: Abdolrahimzadeh S, Plateroti AM, Recupero SM, Lambiase A Abstract Neurofibromatosis type 1, tuberous sclerosis complex, and Von Hippel-Lindau disease, historically classified as the phakomatoses, are hereditary multisystem disorders characterized by the presence of hamartoma, which carry the risk of malignant transformation. The alteration of tumor suppressor genes seems to be at the basis of their pathophysiogenetic mechanism. Lisch and choroidal nodules in neurofibromatosis type 1, retinal astrocytomas in tuberous sclerosis complex, and retinal capillary hemangioma in Von Hippel-Lindau disease are the pr...
Source: Journal of Ophthalmology - August 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Perioperative Ranibizumab Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery.
Conclusions. Although intrapostoperative ranibizumab injection for DME seems to be more effective than preoperative injections in patients undergoing cataract surgery, the treatment still needs to be continued following surgery. PMID: 27493795 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - August 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy.
Authors: Sayın O, Yeter V, Arıtürk N Abstract Aim. To compare the measurements of retinal nerve fiber layer (RNFL), macula and optic disc parameters obtained by optical coherence tomography (OCT), and intraocular pressure (IOP) between the patients with thyroid-associated ophthalmopathy (TAO) and healthy controls. Methods. One hundred and thirty-two eyes of 66 patients with TAO and 72 eyes of 36 healthy controls were included in the study. Proptosis level was determined by Hertel exophthalmometer. Optic disc, peripapillary retinal nerve fiber layer, and macula parameters were measured by OCT. All measurement...
Source: Journal of Ophthalmology - August 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Success Rates of Vitrectomy in Treatment of Rhegmatogenous Retinal Detachment.
Conclusion. The primary anatomical success of PPV for primary uncomplicated RRD was 89.8% and the final anatomical success rate was 100%. PMID: 27478632 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - August 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Long-Term Follow-Up of the Fellow Eye in Patients Undergoing Surgery on One Eye for Treating Myopic Traction Maculopathy.
Conclusions. Long axial length, chorioretinal atrophy, a posterior staphyloma, and anterior traction contribute to MTM development. Patients with high myopia and unilateral MTM require regular OCT monitoring of the fellow eye to assess progression to myopic pre-MTM. For cases exhibiting one or more potential risk factors, early surgical intervention may maximize the visual outcomes. PMID: 27478633 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - August 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Impact of Indocyanine Green Concentration, Exposure Time, and Degree of Dissolution in Creating Toxic Anterior Segment Syndrome: Evaluation in a Rabbit Model.
Conclusion. TASS occurrence may be associated with the concentration, exposure time, and degree of dissolution of ICG dye during cataract surgery. PMID: 27478634 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - August 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Application of OCTA in Assessment of Anti-VEGF Therapy for Idiopathic Choroidal Neovascularization.
Conclusion. Intravitreal injection of anti-VEGF is effective for idiopathic choroidal neovascularization, and the treatment outcomes are observable after 1 day. OCTA provides a useful approach for monitoring and evaluating the treatment of intravitreal anti-VEGF for CNV. PMID: 27471600 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 30, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Small Incision Lenticule Extraction for Postkeratoplasty Myopia and Astigmatism.
Conclusion. SMILE for correction of post-PKP myopia and astigmatism is effective, safe, and stable with moderate accuracy and predictability. Centration of the treatment within the grafts was easily performed. PMID: 27446606 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparative Analysis of KnockOut ™ Serum with Fetal Bovine Serum for the In Vitro Long-Term Culture of Human Limbal Epithelial Cells.
Comparative Analysis of KnockOut™ Serum with Fetal Bovine Serum for the In Vitro Long-Term Culture of Human Limbal Epithelial Cells. J Ophthalmol. 2016;2016:7304812 Authors: Zhang S, Liu Z, Su G, Wu H Abstract The limbal epithelial cells can be maintained on 3T3 feeder layer with fetal bovine serum supplemented culture medium, and these cells have been used to successfully treat limbal stem cell deficiency. However, fetal bovine serum contains unknown components and displays quantitative and qualitative lot-to-lot variations. To improve the culture condition, the defined KnockOut serum replacemen...
Source: Journal of Ophthalmology - July 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Biomechanical Measurement of Rabbit Cornea by a Modified Scheimpflug Device.
Conclusions. The modified Scheimpflug device was a valuable tool to investigate the biomechanics of the cornea. The posterior pressure 15-75 mmHg range produced small viscoelastic deformations and nearly linear pressure-deformation response in the rabbit cornea. PMID: 27446608 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Corrigendum to "Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma".
Corrigendum to "Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma". J Ophthalmol. 2016;2016:8592790 Authors: Moon CH, Han J, Ohn YH, Park TK Abstract [This corrects the article DOI: 10.1155/2015/397495.]. PMID: 27433354 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 21, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Multimodal Imaging Evaluations of Focal Choroidal Excavations in Eyes with Central Serous Chorioretinopathy.
Conclusions. FCE is not uncommon in patients with CSC. Multimodal imaging suggested that the aberrant choroidal circulation might be a contribution factor for leakage from the dysfunctional retinal pigment epithelium at the area of excavation. PMID: 27437148 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 21, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Classifications for Proliferative Vitreoretinopathy (PVR): An Analysis of Their Use in Publications over the Last 15 Years.
Conclusions. Our findings suggest that current classifications are of limited value in clinical practice due to the inconsistent and limited use and that it may be of benefit to produce a revised classification. PMID: 27429798 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide.
Conclusions. This in vivo study has elucidated several genes and pathways that are potentially altering the circadian rhythms and several other neurotransmitter pathways in RPE/choroid during intravitreal steroid injections, which likely has consequences in the dysregulation of RPE function and neurodegeneration of the retina. PMID: 27429799 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Passive Removal of Silicone Oil with Temporal Head Position through Two 23-Gauge Cannulas.
Conclusion. This new approach may provide a safe and fast method to remove the silicone oil. PMID: 27418976 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 17, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction.
This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. Ten ocular surface symptoms were evaluated with a subjective face score at every visit. Best spectacle corrected visual acuity, intraocular pressure (IOP), conjunctival injection, upper and lower tear meniscus height (TMH), tear break-up time (TBUT), corneal staining, lid margin and meibomian gland assessments, and meib...
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

iStent® Trabecular Microbypass Stent: An Update.
iStent® Trabecular Microbypass Stent: An Update. J Ophthalmol. 2016;2016:2731856 Authors: Resende AF, Patel NS, Waisbourd M, Katz LJ Abstract Due to the high rates of complications and failure experienced with current glaucoma procedures, there is a continuous search for a safer and more effective glaucoma surgery. A new class of procedures termed minimally invasive glaucoma surgeries (MIGS) aim to fill this void by offering an alternative method of IOP reduction associated with markedly reduced complication rates and shorter recovery times. The iStent, a trabecular microbypass stent, is a MIGS dev...
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Computational Simulation of Scleral Buckling Surgery for Rhegmatogenous Retinal Detachment: On the Effect of the Band Size on the Myopization.
Authors: Lanchares E, Del Buey MA, Cristóbal JA, Calvo B, Ascaso FJ, Malvè M Abstract A finite element model (FE) of the eye including cornea, sclera, crystalline lens, and ciliary body was created to analyze the influence of the silicone encircling bandwidth and the tightness degree on the myopia induced by scleral buckling (SB) procedure for rhegmatogenous retinal detachment. Intraocular pressure (IOP) was applied to the reference geometry of the FE model and then SB surgery was simulated with encircling bandwidths of 1, 2, and 2.5 mm. Different levels of tightening and three values of IOP we...
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Optical Coherence Tomography Parameters in Morbidly Obese Patients Who Underwent Laparoscopic Sleeve Gastrectomy.
Authors: Dogan B, Dogan U, Erol MK, Habibi M, Bulbuller N Abstract Purpose. To investigate changes in optical coherence tomography parameters in morbidly obese patients who had undergone laparoscopic sleeve gastrectomy (LSG). Methods. A total of 41 eyes of 41 morbidly obese patients (BMI ≥ 40) who had undergone LSG were included in study. The topographic optic disc parameters, central macular thickness (CMT), total macular volume (TMV), and retinal ganglion cell layer (RGCL) were measured by spectral-domain optical coherence tomography (SD-OCT). Subfoveal choroidal thickness (SFCT) was measured by enhanced deep ...
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Relationship between Peeled Internal Limiting Membrane Area and Anatomic Outcomes following Macular Hole Surgery: A Quantitative Analysis.
Conclusion. The findings of the present study show that the peeled ILM area can affect the anatomic outcomes of MH surgery. PMID: 27413544 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study.
This study aimed to identify the microbial etiology of infectious endophthalmitis and to determine the antibacterial susceptibilities of bacterial isolates at an eye hospital in South China. A retrospective analysis was carried out on 330 patients with clinically diagnosed infectious endophthalmitis who underwent microbiological evaluation from January 2010 to December 2014. Of the 330 patients, 193 patients (58.5%) had posttraumatic endophthalmitis, 67 patients (20.3%) had postoperative endophthalmitis, 61 patients (18.5%) had endogenous endophthalmitis, and 9 patients (2.7%) had postcorneal infective endophthalmitis. Of ...
Source: Journal of Ophthalmology - July 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Authors: Dursun A, Ozec AV, Dogan O, Dursun FG, Toker MI, Topalkara A, Arici MK, Erdogan H Abstract Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls. Materials and Methods. In this prospective study, 30 eyes of 30 patients with PEX syndrome, 28 eyes of 28 patients with PEX glaucoma, and 30 eyes of 30 age-matched healthy subjects were enrolled. Choroidal thicknesses in the macular and peripapillary areas were measured by using spectral domain optical coherence tomography. Results. Gender, age,...
Source: Journal of Ophthalmology - July 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison between a New Optical Biometry Device and an Anterior Segment Optical Coherence Tomographer for Measuring Central Corneal Thickness and Anterior Chamber Depth.
Authors: Huang J, Lu W, Savini G, Chen H, Wang C, Yu X, Bao F, Wang Q Abstract Purpose. To compare between a new optical biometer (AL-Scan, Nidek Co., Aichi, Japan) and an anterior segment optical coherence tomographer (Visante AS-OCT, Carl Zeiss Meditec, Dublin, USA) for measuring central corneal thickness (CCT), anterior chamber depth (ACD), and aqueous depth (AD). Methods. Sixty-three eyes of 63 normal subjects were examined with AL-Scan and Visante AS-OCT in this prospective study. One eye per subject was measured three times with both devices to record their CCT, ACD, and AD. All procedures were performed by t...
Source: Journal of Ophthalmology - July 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Identification of the First De Novo UBIAD1 Gene Mutation Associated with Schnyder Corneal Dystrophy.
Conclusions. We present a novel heterozygous de novo missense mutation in UBIAD1, p.(Thr103Ile), identified in a patient with classic clinical features of SCD. This highlights the value of genetic testing in clinical diagnostic settings, even in the absence of a positive family history. PMID: 27382485 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Keratorefractive Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Eyes.
Authors: Du Z, Yan P, Luo Q, Zhang D, Zhang Y Abstract Purpose. To evaluate high intensity focused ultrasound (HIFU) as an innovation and noninvasive technique to correct presbyopia by altering corneal curvature in the rabbit eye. Methods. Eighteen enucleated rabbit eyes were treated with a prototype HIFU keratoplasty. According to the therapy power, these eyes were divided three groups: group 1 (1 W), group 2 (2 W), and group 3 (3 W). The change in corneal power was quantified by a Sirius Scheimpflug camera. Light microscopy (LM) and transmission electron microscopy (TEM) were performed to det...
Source: Journal of Ophthalmology - July 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Prospective Study of the Incidence of Retinopathy of Prematurity in China: Evaluation of Different Screening Criteria.
Authors: Li Q, Wang Z, Wang R, Tang H, Chen H, Feng Z Abstract To investigate the incidence of Retinopathy of Prematurity (ROP) in Beijing, North China, and to evaluate the effectiveness of different ROP screening criteria, we conducted a prospective cohort study in a single-neonatal intensive care unit (NICU). A total of 2997 premature infants with birth weight (BW) ≤ 2000 g and/or gestational age (GA) ≤ 34 weeks had completed ROP screening. ROP was diagnosed in 356 (11.9%) infants. The mean GA was 30.46 ± 1.98 weeks and the mean BW was 1477.35 ± 371.29 g. Of the 59 (2.0%) infants...
Source: Journal of Ophthalmology - July 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease.
Authors: Celebi AR, Mirza GE Abstract Purpose. To compare central corneal thickness (CCT) values via Spectral Domain-Optical Coherence Tomography (SD-OCT) and ultrasonic pachymetry in patients with severe dry eye disease (DED) to determine the level of agreement between these 2 methods. Methods. The paired samples t-test was used to compare CCT values in severe DED patients. Matching analysis between methods was performed using intraclass correlation coefficient (ICC). Intrasession reliability of the measurement methods was calculated via the concordance correlation coefficient (CCC), variation equivalent, and Pear...
Source: Journal of Ophthalmology - July 7, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Assessment of Corneal Epithelial Thickness in Asymmetric Keratoconic Eyes and Normal Eyes Using Fourier Domain Optical Coherence Tomography.
Authors: Catalan S, Cadarso L, Esteves F, Salgado-Borges J, Lopez M, Cadarso C Abstract Purpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n = 22) and normal fellow eyes (n = 22) in patients with asymmetric keratoconus and normal eyes (n = 104) in healthy subjects. Areas under the curve (AUC) of receiver operator characteristic (ROC) curves for each variable were compared across g...
Source: Journal of Ophthalmology - July 7, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Is Floppy Eyelid Syndrome More Prevalent in Obstructive Sleep Apnea Syndrome Patients?
Authors: Wang P, Yu DJ, Feng G, Long ZH, Liu CJ, Li H, Zhao TL Abstract Controversial findings are reported about the relationship between floppy eyelid syndrome (FES) and obstructive sleep apnea syndrome (OSAS). The main goal of this study was to evaluate whether FES is more prevalent in OSAS patients by performing a meta-analysis. A comprehensive literature search of Pubmed, Embase, and Cochrane databases was performed. Only studies related to the prevalence of FES in OSAS were included in the meta-analysis. We estimated a pooled odds ratio (OR) for the prevalence of FES in OSAS. In total, 6 studies with 767 part...
Source: Journal of Ophthalmology - July 2, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Fascicular Visual Field Defects in Open-Angle Glaucoma: Evaluation with Microperimetry.
Conclusions. Topographic visualization of the perimetric alteration by microperimetry allows retesting areas with reduced sensitivity which are topographically visualized and displayable on the ocular fundus examination, avoiding worsening of the functional defect by better modulation of the antiglaucoma therapy and therefore it allows better monitoring of the pathologic functional damage. PMID: 27366329 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - July 2, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Different Power of Near Addition in Two Different Multifocal Intraocular Lenses.
Conclusion. The +2.5 diopters near addition could be a better choice in younger patients with more distance and intermediate visual requirements (driving, outdoor activities), whereas the + 3.0 diopters should be considered for patients with more near vision correction (reading). PMID: 27340560 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Central Corneal Thickness in Spectral-Domain OCT and Associations with Ocular and Systemic Parameters.
Authors: Schuster AK, Fischer JE, Vossmerbaeumer U Abstract Background. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods. A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry, and imaging of the anterior segment by SD-OCT was pe...
Source: Journal of Ophthalmology - June 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Inhibition of Zymosan-Induced Inflammatory Factors Expression by ATRA Nanostructured Lipid Carriers.
Conclusions. ATRA may be a potent anti-inflammatory agent for the therapy of fungal keratitis (FK). PMID: 27340562 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Lecithin-Bound Iodine Prevents Disruption of Tight Junctions of Retinal Pigment Epithelial Cells under Hypoxic Stress.
Conclusions. LBI results in a protective action from hypoxia. PMID: 27340563 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 26, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Cationic Thiolated Poly(aspartamide) Polymer as a Potential Excipient for Artificial Tear Formulations.
Authors: Budai-Szűcs M, Horvát G, Szilágyi BÁ, Gyarmati B, Szilágyi A, Berkó S, Szabó-Révész P, Sandri G, Bonferoni MC, Caramella C, Soós J, Facskó A, Csányi E Abstract Dry eye disease is a relatively common ocular problem, which causes eye discomfort and visual disorders leading to a decrease in the quality of life. The aim of this study was to find a possible excipient for eye drop formulations, which is able to stabilize the tear film. A cationic thiolated polyaspartamide polymer, poly[(N-mercaptoethylaspartamide)-co-(N-(N',N'-dimethyl...
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Effect of Air Pollution on the Occurrence of Nonspecific Conjunctivitis.
Conclusions. The air quality index within two days before presentation affected the probability of attending the outpatient clinic for nonspecific conjunctivitis. High number of cases can be expected in colder season. PMID: 27313867 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Shallow Inferior Conjunctival Fornix in Contracted Socket and Anophthalmic Socket Syndrome: A Novel Technique to Deepen the Fornix Using Fascia Lata Strips.
Conclusion. Fascia lata technique is a new alternative and effective procedure to deepen the shallow inferior fornix that can be used in moderate to severe contracted sockets or anophthalmic socket syndrome with minimal lower eyelid or socket complications. PMID: 27313868 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Refractive Results: Safety and Efficacy of Secondary Piggyback Sensar™ AR40 Intraocular Lens Implantation to Correct Pseudophakic Refractive Error.
Conclusions. Implantation of the second sulcus SensarAR40 IOL was found to be safe, easy, and simple technique for management of ametropia following uncomplicated phacoemulsification. PMID: 27313869 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Morphometric Optic Nerve Head Analysis in Glaucoma Patients: A Comparison between the Simultaneous Nonmydriatic Stereoscopic Fundus Camera (Kowa Nonmyd WX3D) and the Heidelberg Scanning Laser Ophthalmoscope (HRT III).
Authors: Mariacher S, Hipp S, Wirthky R, Blumenstock G, Bartz-Schmidt KU, Ziemssen F, Schiefer U, Voykov B, Januschowski K Abstract Purpose. To investigate the agreement between morphometric optic nerve head parameters assessed with the confocal laser ophthalmoscope HRT III and the stereoscopic fundus camera Kowa nonmyd WX3D retrospectively. Methods. Morphometric optic nerve head parameters of 40 eyes of 40 patients with primary open angle glaucoma were analyzed regarding their vertical cup-to-disc-ratio (CDR). Vertical CDR, disc area, cup volume, rim volume, and maximum cup depth were assessed with both devices by...
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

In Vivo Near-Infrared Fluorescence Imaging of Aqueous Humor Outflow Structures.
Authors: Zeppa L, Ambrosone L, Guerra G, Fortunato M, Costagliola C Abstract The aim of this study has been to visualize the aqueous outflow system in patients affected by primary open angle glaucoma. A solution of indocyanine green (ICG) plus high viscosity viscoelastic solution was injected into the Schlemm canal during surgery in 10 glaucomatous patients undergoing canaloplasty. Soon after injection of the dye the borders of the scleral flap were completely stained due to partial reflux caused by the intrachannel resistance; progression of the dye along the Schlemm canal starting from the site of injection was t...
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison between Limbal and Pars Plana Approaches Using Microincision Vitrectomy for Removal of Congenital Cataracts with Primary Intraocular Lens Implantation.
Conclusions. The visual results were encouraging in both approaches. We recommend the pars plana approach for lower incidence of complications. The limbal approach should be reserved for children older than 3 years of age and caution should be exercised to minimize iris disturbance. PMID: 27313872 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis.
Conclusions. This meta-analysis suggests that open-angle glaucoma patients have significantly decreased peripapillary choroidal thickness compared to healthy individuals. Peripapillary choroidal thickness measured by optical coherence tomography may be an important parameter to consider in open-angle glaucoma. PMID: 27298732 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Assessment of Anterior Segment Changes in Pseudophakic Eyes, Using Ultrasonic Biomicroscopic Imaging, after Pars Plana Vitrectomy with Silicone Oil or Gas Tamponade.
Conclusions. Gases cause more morphological changes in the anterior segment structures. It is thought that complications such as increased intraocular pressure can be seen more frequently for this reason. PMID: 27298733 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Therapeutic Effect of Intrastromal Voriconazole, Topical Voriconazole, and Topical Natamycin on Fusarium Keratitis in Rabbit.
Conclusion. Intrastromal injection of voriconazole seems to be effective in treatment of Fusarium keratitis as much as topical natamycin and these are more effective than topical voriconazole. PMID: 27298734 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study.
Authors: Wang YJ, Yang YN, Huang LY, Wang B, Han YC, Yan JB Abstract Background. To evaluate the optical quality and related factors in patients with ocular hypertension (OHT). Methods. This was a prospective case-control study. A total of 12 eyes with OHT and 20 control eyes underwent testing with Optical Quality Analysis System II (OQAS II) to evaluate the modulation transfer function cut off frequency (MTF cutoff), the Strehl 2D ratio (SR), objective scatter index (OSI), tear-film mean OSI (TFOSI), and the OQAS values (OV100%,OV20%, and OV9%). Results. The optical quality of patients with OHT declined, with lowe...
Source: Journal of Ophthalmology - June 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Intravitreal Ranibizumab Injection as an Adjuvant in the Treatment of Neovascular Glaucoma Accompanied by Vitreous Hemorrhage after Diabetic Vitrectomy.
Conclusions. The findings suggest that intravitreal ranibizumab injection as adjuvant therapy for treatment of NVG accompanied by PDVH may be safe and potentially effective. This clinical trial is registered with NCT02647515. PMID: 27293875 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - June 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Diagnostic Performance of McMonnies Questionnaire as a Screening Survey for Dry Eye: A Multicenter Analysis.
Authors: Guo Y, Peng R, Feng K, Hong J Abstract Purpose. To evaluate the diagnostic performance of the McMonnies questionnaire as a screening survey for dry eye in Chinese outpatients. Methods. The questionnaire was self-administered by 27,999 patients with dry eye symptoms. A thorough ophthalmic examination including tear break-up time (TBUT), fluorescein staining, and Schirmer I test was completed to make a clinical diagnosis of dry eye. Reliability, validity, and accuracy of the McMonnies questionnaire were assessed. Results. The McMonnies questionnaire showed poor internal consistency (Cronbach α = 0.37),...
Source: Journal of Ophthalmology - June 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Use of Mechanical Turk as a MapReduce Framework for Macular OCT Segmentation.
Authors: Lee AY, Lee CS, Keane PA, Tufail A Abstract Purpose. To evaluate the feasibility of using Mechanical Turk as a massively parallel platform to perform manual segmentations of macular spectral domain optical coherence tomography (SD-OCT) images using a MapReduce framework. Methods. A macular SD-OCT volume of 61 slice images was map-distributed to Amazon Mechanical Turk. Each Human Intelligence Task was set to $0.01 and required the user to draw five lines to outline the sublayers of the retinal OCT image after being shown example images. Each image was submitted twice for segmentation, and interrater reliabi...
Source: Journal of Ophthalmology - June 14, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research