Canaloplasty: Current Value in the Management of Glaucoma.
Authors: Cagini C, Peruzzi C, Fiore T, Spadea L, Lippera M, Lippera S Abstract Canaloplasty is a nonpenetrating blebless surgical technique for open-angle glaucoma, in which a flexible microcatheter is inserted within Schlemm's canal for the entire 360 degrees. When the microcatheter exits the opposite end, a 10-0 prolene suture is tied and it is then withdrawn, by pulling microcatheter back through the canal in the opposite direction. Ligation of prolene suture provides tension on the canal and facilitates aqueous outflow. The main advantage of canaloplasty is that this technique avoids the major complications of ...
Source: Journal of Ophthalmology - June 1, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Loop Myopexy Surgery for Strabismus Associated with High Myopia.
Authors: Su Y, Shen Q, Fan X Abstract Strabismus associated with high myopia is a rare abnormality of ocular motility, leading to the impairment of abduction and supraduction. Loop myopexy of the superior rectus (SR) and lateral rectus (LR) muscles is now the most preferred surgery for restoring the dislocated eye globe back into the muscle cone. Various procedural modifications have been made based on this concept, and satisfactory outcomes have been reached in most cases. In this paper, we review various surgical modifications published in the literature that are based on the loop myopexy surgery in patients with...
Source: Journal of Ophthalmology - June 1, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Usefulness of Discarded Vitreous Samples from Routine Vitrectomy.
Authors: Vilà N, Zoroquiain P, Bravo-Filho V, Antecka E, Dietrich H, Chen JC, Galic IJ, Kapusta MA, Burnier MN Abstract Purpose. To describe the histopathological features of vitreous samples obtained after vitrectomy surgery from diabetic and nondiabetic patients. Methods. Vitreous specimens from 137 patients who underwent vitrectomy for different clinical conditions were analysed. All samples were centrifuged and each resulting pellet was fixed and processed as part of routine paraffin section histopathology. The histopathological features were categorized in a semiquantitative fashion. The samples from di...
Source: Journal of Ophthalmology - May 24, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Spectrum and Sensitivity of Bacterial Keratitis Isolates in Auckland.
Conclusions. Despite a shift in the spectrum of bacterial keratitis isolates, antibiotic sensitivity patterns have generally remained stable and show comparability to results within the last decade from NZ centres. PMID: 27213052 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 24, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics.
Authors: Zhang X, Zhao L, Deng S, Sun X, Wang N Abstract There has been substantial progress in our understanding of the ocular surface system/lacrimal function unit in the past 15 years. Keratoconjunctivitis sicca, more commonly referred to as dry eye syndrome (DES), is the most frequently encountered condition and diabetes mellitus (DM) has been identified as one of the leading causes of DES. Poor glycemic control affects both the anterior and the posterior segments of the eye and increasing prevalence of diabetes-associated DES (DMDES) has been reported in recent years. The pathogenesis and specific features of ...
Source: Journal of Ophthalmology - May 24, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Intrastromal Injection of China Painting Ink in Corneas of Male Rabbits: Clinical and Histological Study.
Conclusion. Corneal staining by China painting ink is effective and safe in staining of male rabbits cornea; however further study in human corneas with longer follow-up period is advisable. PMID: 27195146 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 21, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Properties of Retinal Precursor Cells Grown on Vertically Aligned Multiwalled Carbon Nanotubes Generated for the Modification of Retinal Implant-Embedded Microelectrode Arrays.
Conclusions. All tested MWCNT-covered slices showed good biocompatibility profiles, confirming that this nanotechnology is a promising tool to improve prostheses bearing electrodes which connect with retinal tissue. PMID: 27200182 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 21, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Different Strategies for the Treatment of Age-Related Macular Degeneration in China: An Economic Evaluation.
Conclusion. Bevacizumab can be a cost-effective option for the treatment of AMD in the Chinese setting. PMID: 27200183 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 21, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Two-Dimensional Cutting (TDC) Vitrectome: In Vitro Flow Assessment and Prospective Clinical Study Evaluating Core Vitrectomy Efficiency versus Standard Vitrectome.
Authors: Pavlidis M Abstract Purpose. To evaluate comparative aspiration flow performance and also vitrectomy operating time efficiency using a double-cutting open port vitreous cutting system incorporated in a two-dimensional cutting (TDC, DORC International) vitrectome design versus standard vitreous cutter. Methods. In vitro investigations compared aspiration flow rates in artificial vitreous humor at varying cutter speeds and vacuum levels using a TDC vitrectome and a standard vitrectome across different aspiration pump systems. A prospective single-centre clinical study evaluated duration of core vitrectomy in...
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images.
Authors: Phan TV, Seoud L, Chakor H, Cheriet F Abstract Age-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. First, a study was carried out to highlight the most relevant features for AMD characterization based on texture, color, and visual context in fundus images. A support vector machine and a random forest were used to classify images according to the different AMD stages following the AREDS protoc...
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy.
Conclusions. When consulting a patient presenting a VL with unknown age of onset, familial history, or previous retinal diseases, some aspects of multimodal imaging assessment may lead the ophthalmologist to a correct diagnosis. PMID: 27190637 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Hyaluronate Acid-Dependent Protection and Enhanced Corneal Wound Healing against Oxidative Damage in Corneal Epithelial Cells.
Conclusion. HA enhanced corneal epithelial cell wound healing by promoting cell migration, upregulating repair responses, and suppressing inflammatory responses. PMID: 27190638 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Repeatability and Reproducibility of Noninvasive Keratograph 5M Measurements in Patients with Dry Eye Disease.
Authors: Tian L, Qu JH, Zhang XY, Sun XG Abstract Purpose. To determine the intraexaminer repeatability and interexaminer reproducibility of tear meniscus height (TMH) and noninvasive Keratograph tear breakup time (NIKBUT) measurements obtained with the Keratograph 5M (K5M) in a sample of healthy and dry eye populations. Methods. Forty-two patients with dry eye disease (DED group) and 42 healthy subjects (healthy group) were recruited in this prospective study. In all subjects, each eye received 3 consecutive measurements using the K5M for the TMH and NIKBUTs (NIKBUT-first and NIKBUT-average). And then a different ...
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of the Efficacy of Intravitreal Aflibercept and Bevacizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion.
Authors: Wang JK, Su PY, Hsu YR, Chen YJ, Chen FT, Tseng YY Abstract Fifty-two eyes of 52 patients with treatment-naïve macular edema associated with perfused branch retinal vein occlusion were retrospectively reviewed. Twenty-seven cases received PRN intravitreal bevacizumab, and 25 cases were treated by PRN intravitreal aflibercept with monthly follow-ups for 12 months. Both aflibercept and bevacizumab were effective in reduction of macular thickness and improvement of visual acuity for the participants. Both antivascular endothelial growth factor agents had similar efficacy and duration of treatment for the...
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Relationship between Altered Platelet Morphological Parameters and Retinopathy in Patients with Type 2 Diabetes Mellitus.
Authors: Yilmaz T, Yilmaz A Abstract Purpose. To investigate whether platelet morphology or function is altered in patients with diabetic retinopathy (DR). Methods. This prospective study enrolled 85 healthy controls (HCs) (group 1) and 262 patients with Type 2 diabetes mellitus (T2DM). Patients were subclassified into three groups according to ocular findings: no DR (group 2; n = 88); nonproliferative DR (group 3; n = 88), and proliferative DR (group 4; n = 86). Mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (PLCR), plateletcrit (PCT) values, and platelet count were measur...
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Long-Term Observation of Triplex Surgery for Cataract after Phakic 6H Implantation for Super High Myopia.
Conclusions. Triplex surgery was safe and effective for phakic 6H related complicated cataracts. Early extraction before severe ECD loss is recommended. PMID: 27190642 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Performance of Toris K Contact Lens in Patients with Moderate to Advanced Keratoconus: A Real Life Retrospective Analysis.
Authors: Yilmaz I, Ozcelik F, Basarir B, Demir G, Durusoy G, Taskapili M Abstract Objectives. To evaluate the visual performance of Toris K soft contact lenses in patients with moderate-to-advanced keratoconus and also to compare the results according to cone types, cone location, and severity of keratoconus. Materials and Methods. Sixty eyes of 40 participants were included in this retrospective study. Uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BCVA), best-contact lens corrected visual acuity (BCLCVA), and comfort rating via visual analogue scales (VAS) were measured. Results. The me...
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method.
Authors: Ji Y, Zuo C, Lin M, Zhang X, Li M, Mi L, Liu B, Wen F Abstract Purpose. To investigate macular pigment optical density (MPOD) and its relationship with retinal thickness in primary open angle glaucoma (POAG) patients using the one-wavelength reflectometry method. Methods. A total of 30 eyes from 30 POAG patients (18 males and 12 females, mean age 47.27 ± 16.93) and 52 eyes from 52 controls (27 males and 25 females, mean age 49.54 ± 19.15) were included in this prospective, observational, case-control study. MPOD was measured in a 7-degree area using one-wavelength reflectometry method. Two pa...
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population.
Authors: Zhang R, Qian J, Guo J, Yuan Y, Xue K, Yue H, Chen L Abstract Purpose. To describe the clinical manifestations and treatment outcomes of syphilitic uveitis in a Chinese population. Methods. This is a retrospective case series of 15 consecutive patients with syphilitic uveitis treated at a uveitis referral center between 2012 and 2015. Results. Fifteen patients were diagnosed with syphilitic uveitis based on positive serological tests. Nine patients were male. Coinfection with human immunodeficiency virus was detected in two patients. Twenty eyes presented with panuveitis and all patients had posterior invo...
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Stab Incision Glaucoma Surgery: A Modified Guarded Filtration Procedure for Primary Open Angle Glaucoma.
Authors: Jacob S, Figus M, Ashok Kumar D, Agarwal A, Agarwal A, Areeckal Incy S Abstract Purpose. To describe a modified guarded filtration surgery, stab incision glaucoma surgery (SIGS), for primary open angle glaucoma (POAG). Methods. This prospective, interventional case series included patients with POAG (IOP ≥21 mmHg with glaucomatous visual field defects). After sliding superior conjunctiva down over limbus, 2.8 mm bevel-up keratome was used to create conjunctival entry and superficial corneoscleral tunnel in a single step starting 1.5 mm behind limbus. Lamellar corneoscleral tunnel wa...
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Zeaxanthin and Lutein in the Management of Eye Diseases.
Authors: Yang SF, Roberts JE, Liu QH, Pang J, Sarna T PMID: 27144016 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Influence of Septal Deviation on the Prognosis of Transcanalicular Diode Laser-Assisted Dacryocystorhinostomy.
Conclusion. We found no significant statistical differences between the success rates in the two groups (with SD and no anatomical variants). So we could avoid previous or concomitant septoplasty in some cases (mild and moderate SD). PMID: 27144017 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Subconjunctival Injection of Viscoelastic Material for Leaking Sclerotomy in Transconjunctival Sutureless Vitrectomy.
Conclusion. Subconjunctival injection of VEM was simple and effective for the self-sealing of leaking sclerotomy after TSV in selected cases. PMID: 27144018 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes.
Conclusions. The anatomic success rate of retinal reattachment surgery in patients with Down syndrome is comparable to the general population. Patients with Down syndrome should undergo regular ophthalmic examinations for early diagnosis. Despite late diagnosis and the presence of proliferative vitreoretinopathy (PVR) in some patients, favorable anatomical outcomes can be achieved. PMID: 27123341 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 30, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Transcanalicular Multidiode Laser Dacryocystorhinostomy with and without Silicon Tube Intubation.
Conclusion. The results of the study showed that transcanalicular diode laser dacryocystorhinostomy surgery with bicanalicular silicon tube intubation was more successful than the other method of surgery. Consequently, the application of silicone tube intubation in transcanalicular diode laser dacryocystorhinostomy surgery is recommended. PMID: 27127644 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 30, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

In Vivo Imaging of Intraocular Fluidics in Vitrectomized Swine Eyes Using a Digital Fluoroscopy System.
Conclusions. DFS demonstrated differences in fluid dynamics during phacoemulsification in swine eyes with or without prior vitrectomy. In completely vitrectomized eyes, the large ACD, which developed during phacoemulsification, could be reduced by lifting the iris and allowing the fluid to shift to the posterior cavity. Recognizing the differences in fluidics of vitrectomized eyes as compared to those of the nonvitrectomized eyes may reduce the frequency of intraoperative complications. PMID: 27127645 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 30, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Accuracy of Intraocular Lens Power Calculation Formulas for Highly Myopic Eyes.
Conclusions. Barrett Universal II formula produced the lowest predictive error and the least variable predictive error compared with the SRK/T, Haigis, Holladay, and Hoffer Q formulas. For high myopic eyes, the Barrett Universal II formula may be a more suitable choice. PMID: 27119018 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 29, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Comparison of Clinical Outcomes of Dislocated Intraocular Lens Fixation between In Situ Refixation and Conventional Exchange Technique Combined with Vitrectomy.
Conclusion. The in situ refixation technique should be preferentially considered if surgery is indicated since it seemed to produce a sustained less SIA compared to IOL exchange. PMID: 27119019 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 29, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Long-Term Outcomes of External Dacryocystorhinostomy in the Age of Transcanalicular Microendoscopic Techniques.
Conclusion. In cases in which transcanalicular microendoscopic techniques are contraindicated (e.g., after dacryocystitis) or in complex cases where microendoscopic procedures have failed (revision surgery), external DCR is still the surgical treatment of choice with very good postoperative success. PMID: 27110391 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 27, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

SENP1-Mediated Desumoylation of DBC1 Inhibits Apoptosis Induced by High Glucose in Bovine Retinal Pericytes.
This study investigated the role of SENP1 in pericyte loss in diabetic retinopathy. We demonstrated that a high concentration of glucose inhibited the expression of the Sentrin/SUMO-specific protease 1 (SENP1), which resulted in an increase in DBC1 sumoylation in bovine retinal pericytes (BRPCs). Furthermore, SENP1 overexpression attenuated hyperemia-induced apoptosis of BPRCs, and SENP1 knockdown aggravated this effect. We also provide evidence that DBC1 sumoylation/desumoylation is involved in the SENP1-regulated apoptosis of BRPCs under high glucose conditions. Understanding the role of SENP1 in the pathogenesis of high...
Source: Journal of Ophthalmology - April 27, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comment on "The Effects of Hemodialysis on Tear Osmolarity".
Comment on "The Effects of Hemodialysis on Tear Osmolarity". J Ophthalmol. 2016;2016:6890685 Authors: Ayyildiz O, Ozge G PMID: 27110393 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 27, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Diagnostic Accuracy of Optical Coherence Tomography Angiography for Neovascular Age-Related Macular Degeneration: A Comparison with Fundus Fluorescein Angiography.
Authors: Gong J, Yu S, Gong Y, Wang F, Sun X Abstract Purpose. To describe the morphological characteristics and efficacy of OCTA in detecting CNV in nAMD. We retrospectively reviewed 53 patients (86 eyes) with suspected CNV secondary to wet AMD. All the patients underwent a multimodal assessment for CNV. Two independent readers calculated the sensitivity and specificity of OCTA in detecting CNV compared with FA. A qualitative analysis of OCTA was also performed to describe the morphological appearance of CNV. Among 86 eyes of 53 patients, 52 eyes were diagnosed as having CNV based on the FA imaging analysis. Accor...
Source: Journal of Ophthalmology - April 27, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluating the Functionality of Conjunctiva Using a Rabbit Dry Eye Model.
Conclusions. DE biomarkers are important tools for OS assessment and MUC5AC expression is elevated in rabbit DE. PD measurement revealed significant electrophysiological changes in rabbits with surgery. PMID: 27088007 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Microperimetric Assessment after Epiretinal Membrane Surgery: 4-Year Follow-Up.
Authors: Dal Vecchio M, Lavia C, Nassisi M, Grignolo FM, Fea AM Abstract Purpose. To investigate retinal function using microperimetry in patients affected by idiopathic epiretinal membrane (iERM) and cataract who underwent combined surgery: 4-year follow-up. Design. Prospective, interventional case series. Methods. 30 eyes of 30 consecutive patients with iERM and age-related cataract underwent 25-gauge vitrectomy and cataract surgery. At baseline, 90 and 180 days, and 1 and 4 years, we examined retinal mean sensitivity (MS), retinal mean defect (MD), fixation stability, and frequency of microscotomas using MP1 mic...
Source: Journal of Ophthalmology - April 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease.
Authors: Jehangir N, Bever G, Mahmood SM, Moshirfar M Abstract Numerous designs of punctal and canalicular plugs are available on the market. This variety presents challenges to ophthalmologists when choosing punctal plugs for the management of various ocular conditions. The aim of this literature review is to provide a classification system for lacrimal occlusive devices based on their location and duration of action as well as to identify different characteristics of each one of them. We want to give a comprehensive overview on punctal and canalicular plugs including their manufacturing companies, indications, an...
Source: Journal of Ophthalmology - April 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Peripapillary Retinoschisis in Glaucoma Patients.
Authors: Bayraktar S, Cebeci Z, Kabaalioglu M, Ciloglu S, Kir N, Izgi B Abstract Purpose. To investigate peripapillary retinoschisis and its effect on retinal nerve fiber layer (RNFL) thickness measurements by using spectral-domain optical coherence tomography (SD-OCT) in glaucomatous eyes. Methods. Circumpapillary RNFL (cpRNFL) B-scan images of 940 glaucoma patients (Group 1) and 801 glaucoma-suspect patients (Group 2) obtained by SD-OCT were reviewed. The structural and clinical characteristics of the retinoschisis were investigated. The RNFL thickness measurements taken at the time of retinoschisis diagnosis and...
Source: Journal of Ophthalmology - April 15, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Axial Length of the Eyeball Is Important in Secondary Dislocation of the Intraocular Lens, Capsular Bag, and Capsular Tension Ring Complex.
Conclusion. Longer axial length may contribute to the failure of the CTR to prevent in-the-bag IOL dislocation. Traumatic dislocation appears to be well fixed with the CTR. PMID: 27069675 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 15, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Epidemiological and Clinical Baseline Characteristics as Predictive Biomarkers of Response to Anti-VEGF Treatment in Patients with Neovascular AMD.
Conclusion. Several baseline characteristics correlated with anti-VEGF treatment response, including best-corrected visual acuity, age, lesion size, and retinal thickness. The majority of factors were associated with disease duration, suggesting that longer disease duration before treatment results in worse treatment outcomes. This highlights the need for early treatment for patients with nAMD to gain optimal treatment outcomes. Many of the identified baseline characteristics are interconnected and cannot be evaluated in isolation; therefore multivariate analyses will be required to determine any specific relationship with...
Source: Journal of Ophthalmology - April 15, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Management of Ocular Siderosis: Visual Outcome and Electroretinographic Changes.
Conclusion. A retained iron-containing IOFB can manifest itself after several years with features of OS. A careful clinical and radiologic evaluation is imperative in patients with history suggestive of penetrating ocular injury to rule out retained or occult IOFB and thus prevent this catastrophic condition. PMID: 27073692 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 15, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Increased Macular Pigment Optical Density and Visual Acuity following Consumption of a Buttermilk Drink Containing Lutein-Enriched Egg Yolks: A Randomized, Double-Blind, Placebo-Controlled Trial.
Conclusion. Daily consumption of a dairy drink containing lutein-enriched egg yolks for one year improves visual acuity, MPOD, and plasma lutein concentration in elderly subjects with drusen and/or retinal pigment epithelial abnormalities. PMID: 27064326 [PubMed - as supplied by publisher] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 12, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Guided and Unguided Ocriplasmin Injection for the Treatment of Vitreomacular Traction: A Preliminary Study.
Authors: Mastropasqua R, Di Antonio L, Ciciarelli V, Aharrh-Gnama A, Rispoli M, Carpineto P Abstract This retrospective quality control study aimed at comparing resolution in patients treated with intravitreal ocriplasmin (IVO) using two injection techniques, classical injection procedure (unguided) and targeted injection using a surgical microscope with a 30-gauge 1-inch needle (guided) for the treatment of focal VMT without macular hole. The two groups presented a statistically significant difference in terms of resolution of VMT within the first month following treatment: 1/7 for the unguided group versus 6/7 fo...
Source: Journal of Ophthalmology - April 12, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Assessment of Optical Quality at Different Contrast Levels in Pseudophakic Eyes.
Authors: Park CW, Kim H, Joo CK Abstract Purpose. To assess visual function using Optical Quality Analysis System (OQAS) at varying levels of contrast in pseudophakic eyes. Methods. The study included patients admitted to Seoul St. Mary's Hospital between January and February 2012: 143 pseudophakic eyes with one of five intraocular lens types, examined 2-6 months after cataract surgery, and 93 normal eyes (enhanced visual acuity (VA)
Source: Journal of Ophthalmology - April 9, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comment on "Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia with Convergence Insufficiency".
Comment on "Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia with Convergence Insufficiency". J Ophthalmol. 2016;2016:8236314 Authors: Ceylan OM, Ayyildiz O, Gokce G, Mutlu FM PMID: 27057350 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 9, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Changes of Corneal Wavefront Aberrations in Dry Eye Patients after Treatment with Artificial Lubricant Drops.
Authors: Lu N, Lin F, Huang Z, He Q, Han W Abstract Purpose. To evaluate the corneal aberration changes in dry eye patients after treatment with artificial eye drops. Methods. Thirty mild to moderate dry eye patients treated with artificial eye drops and twenty comparable dry eye patients were recruited as controls. Anterior corneal aberrations over 3 mm and 5 mm analytical zones including total, 3rd to 5th high order aberrations (HOAs), spherical aberration (SA), and vertical (V-coma) and horizontal coma (H-coma) obtained from corneal topography data at baseline and 2 weeks after treatment were evalu...
Source: Journal of Ophthalmology - April 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Corneal-Based Surgical Presbyopic Therapies and Their Application in Pseudophakic Patients.
Authors: Paley GL, Chuck RS, Tsai LM Abstract Purpose. The purpose of this review is to provide a summary of laser refractive surgery and corneal inlay approaches to treat presbyopia in patients after cataract surgery. Summary. The presbyopic population is growing rapidly along with increasing demands for spectacle independence. This review will focus on the corneal-based surgical options to address presbyopia including various types of corneal intrastromal inlays and laser ablation techniques to generate either a multifocal cornea ("PresbyLASIK") or monovision. The natural history of presbyopia develops ...
Source: Journal of Ophthalmology - April 8, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Meta-Analysis of Studies Evaluating Visual and Anatomical Outcomes in Patients with Treatment Resistant Neovascular Age-Related Macular Degeneration following Switching to Treatment with Aflibercept.
Authors: Seguin-Greenstein S, Lightman S, Tomkins-Netzer O Abstract With the introduction of aflibercept, eyes with neovascular age-related macular degeneration (AMD) not responding well to injections of ranibizumab or bevacizumab can be switched to treatment with aflibercept. We carried out a meta-analysis to analyze all available evidence of visual and anatomical outcomes of eyes with resistant neovascular AMD switched to aflibercept at six months. Data from seven retrospective and prospective studies looking at change in best corrected visual acuity (BCVA) and central retinal thickness (CRT) were included. Weigh...
Source: Journal of Ophthalmology - April 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Review: The Lacrimal Gland and Its Role in Dry Eye.
Authors: Conrady CD, Joos ZP, Patel BC Abstract The human tear film is a 3-layered coating of the surface of the eye and a loss, or reduction, in any layer of this film may result in a syndrome of blurry vision and burning pain of the eyes known as dry eye. The lacrimal gland and accessory glands provide multiple components to the tear film, most notably the aqueous. Dysfunction of these glands results in the loss of aqueous and other products required in ocular surface maintenance and health resulting in dry eye and the potential for significant surface pathology. In this paper, we have reviewed products of the la...
Source: Journal of Ophthalmology - April 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Viscoat Assisted Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes Associated with High Myopia.
Conclusion. Vitrectomy combined with Viscoat assisted inverted ILM flap technique is an effective treatment for large MHs in highly myopic eyes. It may increase the success rate of the initial surgery and enhance the anatomical and functional outcomes. PMID: 27047686 [PubMed - as supplied by publisher] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Effects of Lutein on Hyperosmoticity-Induced Upregulation of IL-6 in Cultured Corneal Epithelial Cells and Its Relevant Signal Pathways.
Authors: Chao SC, Nien CW, Iacob C, Hu DN, Huang SC, Lin HY Abstract Dry eye is a common disorder characterized by deficiency of tear. Hyperosmoticity of tear stimulates inflammation and damage of ocular surface tissues and plays an essential role in the pathogenesis of dry eye. Cultured human corneal epithelial (CE) cells were used for the study of effects of lutein and hyperosmoticity on the secretion of IL-6 by CE cells. Cell viability of CE cells was not affected by lutein at 1-10 μM as determined by MTT assay. Hyperosmoticity significantly elevated the secretion of IL-6 by CE cells as measured by ELI...
Source: Journal of Ophthalmology - April 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Dealings between Cataract and Retinal Reattachment Surgery in PVR.
Conclusions. Retinal reattachment surgery seems to benefit from preoperative cataract removal. We found significant lens changes in the nucleus as well as in the layers anterior and posterior to it. This corresponds to the histology of the lens epithelium published before. PMID: 27034821 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research