A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy.
Conclusions. Conbercept pretreatment could be an effective adjunct to vitrectomy in accelerating postoperative vitreous clear-up and acquiring stable visual acuity restoration for PDR. PMID: 27034822 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Controlled Study on the Correlation between Tear Film Volume and Tear Film Stability in Diabetic Patients.
Conclusion. Diabetes affects the tear film in various ways. Diabetics should be examined for dry eye signs even in absence of symptoms which may be masked by associated neuropathy. Duration of diabetes has an impact on tear film status. PMID: 27034823 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - April 3, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Exotropia Is the Main Pattern of Childhood Strabismus Surgery in the South of China: A Six-Year Clinical Review.
Authors: Yu X, Ji Z, Yu H, Xu M, Xu J Abstract Purpose. To evaluate the distribution pattern and changes of strabismus surgery in children based on the data collected from a local eye hospital in the south of China between 2006 and 2011. Methods. A retrospective analysis of all strabismus surgeries in children (
Source: Journal of Ophthalmology - March 31, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Radial Retinotomies with Endodiathermy for Severe Proliferative Vitreoretinopathy: Short-Term Results.
Conclusion. Radial retinotomies with endodiathermy were shown to be feasible, effective, and safe in selected cases of inferior contracted retina without vitreous base fibrosis over a 6-month observation period. This trial is registered with NCT02201706. PMID: 27022477 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 31, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Clinical Outcomes after Uncomplicated Cataract Surgery with Implantation of the Tecnis Toric Intraocular Lens.
Authors: Lubiński W, Kaźmierczak B, Gronkowska-Serafin J, Podborączyńska-Jodko K Abstract Purpose. To evaluate the clinical outcomes after uncomplicated cataract surgery with implantation of an aspheric toric intraocular lens (IOL) during a 6-month follow-up. Methods. Prospective study including 27 consecutive eyes of 18 patients (mean age: 66.1 ± 11.4 years) with a visually significant cataract and corneal astigmatism ≥ 0.75 D and undergoing uncomplicated cataract surgery with implantation of the Tecnis ZCT toric IOL (Abbott Medical Optics). Visual, refractive, and keratometric outcomes as wel...
Source: Journal of Ophthalmology - March 31, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Efficacy and Safety in Retinal Vein Occlusion Treated with at Least Three Consecutive Intravitreal Dexamethasone Implants.
Conclusion. Repeated DI on an "as-needed" basis, with a retreatment interval
Source: Journal of Ophthalmology - March 31, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

National Eye Institute Visual Function Scale in Type 2 Diabetes Patients.
Discussion. Difference was based not on the diabetes duration, clinically significant cataract (CSCat), CSME presence, and DRP stage but on the visual acuity levels of the better seeing eye of the patients. PMID: 26998350 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 22, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Diplopia as the Complication of Cataract Surgery.
Authors: Gawęcki M, Grzybowski A Abstract The authors present systematic review of aetiology and treatment of diplopia related to cataract surgery. The problem is set in the modern perspective of changing cataract surgery. Actual incidence is discussed as well as various modalities of therapeutic options. The authors provide the guidance for the contemporary cataract surgeon, when to expect potential problem in ocular motility after cataract surgery. PMID: 26998351 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 22, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography.
Authors: Lévêque PM, Zéboulon P, Brasnu E, Baudouin C, Labbé A Abstract Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A). Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded...
Source: Journal of Ophthalmology - March 22, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Visual Recovery after Primary Retinal Detachment Surgery: Biofeedback Rehabilitative Strategy.
Authors: Vingolo EM, Fragiotta S, Domanico D, Limoli PG, Nebbioso M, Spadea L Abstract Purpose. To evaluate possible speeding up recovery time after retinal detachment (RD) surgery using biofeedback strategy. Methods. A total of 52 eyes were selected. After surgery, patients were divided into two groups: group A, including patients submitted to biofeedback with MP-1 strategy; group B, patients who received common care strategy. Biofeedback strategy was started 15 days after the suspension of cycloplegic eye drops in buckling procedure or after silicone oil removal in the vitrectomized eyes. Controls were scheduled ...
Source: Journal of Ophthalmology - March 22, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Optical Coherence Tomography: An Adjunctive Tool for Differentiating between Choroidal Melanoma and Metastasis.
Authors: Vishnevskia-Dai V, Zur D, Yaacobi S, Moroz I, Newman H, Neudorfer M Abstract Purpose. To investigate the value of optical coherence tomography (OCT) for differentiation between choroidal melanoma and metastasis based on characteristics of the anterior choroidal surface and the chorioretinal interface. Methods. This retrospective observational case series included 29 patients with untreated choroidal melanomas and 21 patients with untreated choroidal metastases. Regularity and lobularity characteristics of the anterior choroidal surface were evaluated in a masked manner. Retinal and retinal pigment epitheli...
Source: Journal of Ophthalmology - March 22, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Surgical Outcomes between Canaloplasty and Schlemm's Canal Scaffold at 24 Months' Follow-Up.
Authors: Gandolfi SA, Ungaro N, Ghirardini S, Tardini MG, Mora P Abstract The results of canaloplasty (CP) and Hydrus Microstent (HM) implantation were retrospectively compared at 24 months' follow-up in a cohort of subjects referred to our Institution for uncontrolled IOP in primary or secondary (e.g., pseudoexfoliative and pigmentary) open-angle glaucoma. The outcome was labelled as "complete" success, "qualified" success, or "failure" if, two years after surgery, the eyes operated on needed "no" hypotensive medications, "some" hypotensive medications, or further ...
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Retro-Mode Scanning Laser Ophthalmoscopy Planning for Navigated Macular Laser Photocoagulation in Macular Edema.
Conclusion. The RM-SLO image superimposed onto the fundus of the same eye can be used to guide MLP with narrow variability in treatment planning among retina specialists. The treatment areas suggested by RM-SLO-guided MLP plans for ME were shown to be larger than those suggested by OCT-guided plans. PMID: 26989498 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Subconjunctival Mitomycin C and 5-Fluorouracil Injection for Needle Revision of Early Failed Trabeculectomy Blebs.
Authors: Liu W, Wang J, Zhang M, Tao Y, Sun Y Abstract Background. To compare the efficacy of needle revision with 5-fluorouracil (5-FU) and mitomycin C (MMC) on dysfunctional filtration blebs shortly after trabeculectomy. Methods. It is a prospective randomized study comparing needle revision augmented with MMC or 5-FU for failed trabeculectomy blebs. Results. To date 71 patients (75 eyes) have been enrolled, 40 eyes in the MMC group and 35 in the 5-FU group. 68 patients (72 eyes) have completed 12-month follow-up, 38 eyes in the MMC group and 34 in the 5-FU group. The mean IOP before and that after needle revisio...
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Subfoveal Choroidal Thickness in Internal Carotid Artery Stenosis.
Conclusions. Compensatory SFCT increase can be seen in ipsilateral internal carotid artery stenosis greater than 70%. PMID: 26989500 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Challenging Glaucomas: Update on Diagnosis and Management.
Authors: Scuderi G, Khaw PT, Medeiros FA, Manni G PMID: 26989501 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Wound Integrity of 2.0 mm Transconjunctival Single-Plane Sclerocorneal Incision: A Comparison between a Motorized Injector with/without Pause Time and a Manual Injector.
Wound Integrity of 2.0 mm Transconjunctival Single-Plane Sclerocorneal Incision: A Comparison between a Motorized Injector with/without Pause Time and a Manual Injector. J Ophthalmol. 2016;2016:8129298 Authors: Imai H, Fujii A, Tani E, Azumi A Abstract Purpose. To compare the final incision size and wound structure after the intraocular lens implantation from 2.0 mm transconjunctival single-plane sclerocorneal incision (TSSI) between the use of a motorized injector at first speed and the use of a manual injector. Methods. Patients were divided into three groups as follows: Group A, a manu...
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery.
Conclusion. Both 3.0% diquafosol and 0.05% cyclosporine A were effective in treating dry eye after cataract surgery. Diquafosol was more effective in increasing the tear secretion, but cyclosporine A was more effective in improving optical aberrations. PMID: 26989503 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

The Cost of Blindness in the Republic of Ireland 2010-2020.
Conclusions. Here, ninety-eight percent of the cost of blindness is borne by the Departments of Social Protection and Finance and not by the Department of Health as might initially be expected. Cost of illness studies should play a role in public policy making as they help to quantify the indirect or "hidden" costs of disability and so help to reveal the true cost of illness. PMID: 26981276 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 18, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland.
Conclusions. Our findings support our hypothesis that the GH/IGF-1 axis plays a significant role in the control of the meibomian gland. In addition, our data show that GH modulates the morphology and size of this tissue. PMID: 26981277 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 18, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients.
Conclusions. FAF and optimized-FAF imaging showed significant alterations related to DR not observed in colour imaging. FAF and optimized-FAF images could be a useful complementary tool for detecting early alterations associated with the development and progression of DR. PMID: 26977312 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Intravitreal Melphalan for Vitreous Seeds: Initial Experience in China.
Conclusion. Intravitreal melphalan achieved a high local control rate for vitreous seeds without extraocular extension and with acceptable toxicity in Chinese retinoblastoma patients. PMID: 26977313 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 16, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy.
Authors: Şahin M, Şahin A, Elbey B, Yüksel H, Türkcü FM, Cingü AK Abstract Objective. We aimed to investigate the mean platelet volume (MPV) of the patients with nonarteritic anterior ischemic optic neuropathy (NAION). Methods. The medical records of 46 patients with the diagnosis of NAION and 90 control subjects were retrospectively evaluated. All participants underwent complete ocular examination including intraocular pressure (IOP) measurement. Hematocrit, MPV, hemoglobin, and platelet levels of the patients with NAION were compared with those of control subjects. Results. There was no sign...
Source: Journal of Ophthalmology - March 13, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Two Different OCT Systems: Retina Layer Segmentation and Impact on Structure-Function Analysis in Glaucoma.
Authors: Brandao LM, Ledolter AA, Schötzau A, Palmowski-Wolfe AM Abstract Purpose. To compare two different spectral-domain optical coherence tomography (OCT) systems in regard to full macular thickness (MT) and ganglion cell layer-inner plexiform layer (GCIPL) measures and in regard to structure-function correlation when compared to standard automated perimetry (SAP). Methods. Seventeen primary open angle glaucoma patients and 16 controls (one eye per subject) were enrolled. MT and GCIPL thicknesses were measured by Cirrus and Spectralis OCTs. Octopus Perimeter 101 (G2 protocol) reports sensitivity in mean de...
Source: Journal of Ophthalmology - March 13, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Surgical and Functional Results of Hybrid 25-27-Gauge Vitrectomy Combined with Coaxial 2.2 mm Small Incision Cataract Surgery.
Surgical and Functional Results of Hybrid 25-27-Gauge Vitrectomy Combined with Coaxial 2.2 mm Small Incision Cataract Surgery. J Ophthalmol. 2016;2016:9186351 Authors: Höhn F, Kretz F, Pavlidis M Abstract Purpose. To investigate outcomes after coaxial 2.2 mm small incision cataract surgery combined with hybrid 25-27-gauge vitrectomy in eyes with vitreoretinal disease and age-related cataract. Methods. A single-center, retrospective case series study of 55 subjects (55 eyes) with a mean age of 70 years who underwent combined small incision phacoemulsification, intraocular lens (IOL) i...
Source: Journal of Ophthalmology - March 13, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Relationship between Daytime Sleepiness and Intrinsically Photosensitive Retinal Ganglion Cells in Glaucomatous Disease.
Authors: Gracitelli CP, Duque-Chica GL, Moura AL, Roizenblatt M, Nagy BV, de Melo GR, Borba PD, Teixeira SH, Tufik S, Ventura DF, Paranhos A Abstract Patients with glaucoma showed to have higher daytime sleepiness measured by Epworth sleepiness scale. In addition, this symptom was associated with pupillary reflex and polysomnography parameters. These ipRGC functions might be impaired in patients with glaucoma, leading to worse quality of life. PMID: 26955483 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 10, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

High MMP-9 Expression May Contribute to Retroprosthetic Membrane Formation after KPro Implantation in Rabbit Corneal Alkali Burn Model.
Conclusions. Our study evidenced the potential pathophysiological role of MMP-9 expression in RPM formation following KPro implantation. PMID: 26949542 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 9, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Conjunctival Lymphangiogenesis Was Associated with the Degree of Aggression in Substantial Recurrent Pterygia.
Conclusions. Lymphangiogenesis was associated with the degree of aggression in recurrent pterygia, particularly in substantial Grade 3 recurrent pterygia. PMID: 26941998 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Restoration of the Ellipsoid Zone and Visual Prognosis at 1 Year after Surgical Macular Hole Closure.
Authors: Hasebe H, Matsuoka N, Terashima H, Sasaki R, Ueda E, Fukuchi T Abstract Purpose. To evaluate the restoration of the ellipsoid zone (EZ) and its influence on visual prognosis 1 year after surgical macular hole (MH) closure. Method. Subjects were patients with stage 2, 3, or 4 idiopathic MH who underwent primary vitrectomy that resulted in successful hole closure. Nineteen eyes with both EZ disruption with foveal detachment and a continuous external limiting membrane on optical coherence tomography during the early postoperative period were included in this study. Result. EZ disruption was restored in 10 eye...
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study.
Conclusion. The basal tear secretion and tear film stability were lower while the dry eye symptoms such as itching and redness were more common among children with ESRF. The duration of ESRF and dialysis duration seem to be related to the disturbances in tear secretion and tear film stability. However, SMCE is very rare. PMID: 26942000 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of LATS1 and LATS2 Promoter Methylation with the Risk of Pterygium Formation.
Authors: Najafi M, Kordi-Tamandani DM, Arish M Abstract Purpose. Pterygium is a serious eye problem in countries with high exposure to UV. However, despite numerous studies, the molecular etiology of pterygium is unclear. Recent studies have indicated that LATS1 and LATS2 genes are involved in DDR signaling pathways against continuous UV exposure. Our aim was to evaluate the LATS1 and LATS2 promoter methylation with the risk of pterygium formation. Methods. We evaluated the promoter methylation status of LATS1 and LATS2 using methylation-specific PCR technique. Also, mRNA expression of LATS1 and LATS2 was assessed ...
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Elevated Transforming Growth Factor-β2 in the Aqueous Humor: A Possible Explanation for High Rate of Capsular Contraction Syndrome in High Myopia.
Elevated Transforming Growth Factor-β2 in the Aqueous Humor: A Possible Explanation for High Rate of Capsular Contraction Syndrome in High Myopia. J Ophthalmol. 2016;2016:5438676 Authors: Zhang K, Zhu X, Chen M, Sun X, Yang J, Zhou P, Lu Y Abstract Purpose. The purpose of the study was to elucidate the role of transforming growth factor-beta 2 (TGF-β2) in the development of high myopic capsular contraction syndrome. Methods. Nineteen cases of capsular contraction syndrome, including 14 with high myopia, were collected, and their clinical data were reviewed. Aqueous humor and anterior capsular...
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone.
Conclusions. We evaluated a novel treatment for SRD associated with DSM and staphyloma margin in myopic patients. After six months of treatment with the mineralocorticoid antagonist spironolactone, the subretinal fluid and CRT were significantly reduced; however, there was no improvement in BCVA. PMID: 26942003 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Nonlethal Levels of Zeaxanthin Inhibit Cell Migration, Invasion, and Secretion of MMP-2 via NF-κB Pathway in Cultured Human Uveal Melanoma Cells.
Nonlethal Levels of Zeaxanthin Inhibit Cell Migration, Invasion, and Secretion of MMP-2 via NF-κB Pathway in Cultured Human Uveal Melanoma Cells. J Ophthalmol. 2016;2016:8734309 Authors: Bi MC, Hose N, Xu CL, Zhang C, Sassoon J, Song E Abstract Zeaxanthin at nonlethal dosages (3-10 μM) significantly inhibited the cell migration of cultured uveal melanoma cells (C918 cell line) as determined by wound healing assay and Boyden chamber assay. Matrigel invasion assay showed that cell invasion of uveal melanoma cells could be significantly inhibited by zeaxanthin. Secretion of MMP-2 by melano...
Source: Journal of Ophthalmology - March 6, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Ocular Surface Epithelial Thickness Evaluation in Dry Eye Patients: Clinical Correlations.
Conclusions. In dry eye patients, a thinner limbal epithelium and a thicker bulbar conjunctival epithelium were observed. These changes were correlated to the severity of dry eye symptoms and tear film alterations. PMID: 26925258 [PubMed - as supplied by publisher] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - March 1, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Choroidal Thickness in Patients with Mild Cognitive Impairment and Alzheimer's Type Dementia.
Authors: Bulut M, Yaman A, Erol MK, Kurtuluş F, Toslak D, Doğan B, Turgut Çoban D, Kaya Başar E Abstract Aim. To asses both choroidal thickness differences among Alzheimer's type dementia (ATD) patients, mild cognitive impairment (MCI) patients, and healthy control (C) subjects and choroidal thickness relationships with cognitive performance. Methods. A total of 246 eyes of 123 people (41 ATD, 38 MCI, and 44 healthy C subjects) were included in this study. Complete ophthalmological and neurological examination was performed in all subjects. Choroidal thicknesses (CT) were measured at seven locations: the ...
Source: Journal of Ophthalmology - March 1, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Influence of Endothelin-1 in Aqueous Humor on Intermediate-Term Trabeculectomy Outcomes.
Conclusion. In this set of patients, ET-1 in aqueous humor does not appear to have influenced surgical outcome of trabeculectomy with Mitomycin C. There is no indication of an increased likelihood of bleb fibrosis in patients with increased ET-1 concentrations. PMID: 26904271 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 25, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

High Levels of 17β-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye.
High Levels of 17β-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye. J Ophthalmol. 2016;2016:2415867 Authors: Shen G, Ma X Abstract Purpose. To determine the serum levels of sex steroids and tear matrix metalloproteinases (MMP) 2 and 9 concentrations in postmenopausal women with dry eye. Methods. Forty-four postmenopausal women with dry eye and 22 asymptomatic controls were enrolled. Blood was drawn and analyzed for serum levels of sex steroids and lipids. Then, the following tests were performed: tear...
Source: Journal of Ophthalmology - February 25, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Relationship between Corneal Temperature and Intraocular Pressure in Healthy Individuals: A Clinical Thermographic Analysis.
Authors: Fabiani C, Li Voti R, Rusciano D, Mutolo MG, Pescosolido N Abstract Purpose. To study the geographical distribution of corneal temperature (CT) and its influence on the intraocular pressure (IOP) of healthy human volunteers. Materials and Methods. Fifteen subjects (7 M, 8 F), 33.8 ± 17.4 years old, were enrolled in this pilot, cross-sectional study. Measurements of CT were taken after one hour with closed eyelids (CET) or closed eyelids with a cooling mask (cm-CET) and compared to baseline. Results. If compared to baseline, after CET, average CT significantly increased by 0.56°C in the RE and by...
Source: Journal of Ophthalmology - February 25, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation.
Authors: Yu AY, Guo H, Wang QM, Bao FJ, Huang JH Abstract Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (intracameral group), and the contralateral eye received 3 drops of compound tropicamide 0.5% and phenylephrine 0.5% at 5-minute intervals 30 minutes before surg...
Source: Journal of Ophthalmology - February 25, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia.
Authors: Gu Y, Xu B, Feng C, Ni Y, Wu Q, Du C, Hong N, Li P, Ding Z, Jiang B Abstract The mouse model has been widely employed to explore the mysteries of myopia. For now, existing techniques for induction of experimental myopia in mice can be classified into three types: (1) devices directly glued to the fur; (2) devices attached using a combination of glue and sutures; (3) devices attached using a skull-mounted apparatus. These techniques each have its advantages, disadvantages when considering the devices stability, safety, complexity, effectiveness, and so forth. Thus, techniques for myopia induction in mice ha...
Source: Journal of Ophthalmology - February 25, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Pathogenesis of Common Ocular Diseases.
Authors: Zhang J, Tuo J, Wang Z, Zhu A, Machalińska A, Long Q PMID: 26881057 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Novice Reviewers Retain High Sensitivity and Specificity of Posterior Segment Disease Identification with iWellnessExam™.
Conclusions. Novices can be trained to screen for posterior segment disease efficiently and effectively using iWellnessExam™ data, with high sensitivity, while maintaining high specificity. Novice reviewer accuracy covaries with both clinical exposure and time spent per image set. These findings support exploration of training nonophthalmic technicians in a primary medical care setting. PMID: 26881058 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph.
This study aims to evaluate dry eye and ocular surface conditions of myopic teenagers by using questionnaire and clinical examinations. Methods. A total of 496 eyes from 248 myopic teenagers (7-18 years old) were studied. We administered Ocular Surface Disease Index (OSDI) questionnaire, slit-lamp examination, and Keratograph 5M. The patients were divided into 2 groups based on OSDI dry eye standard, and their ocular surfaces and meibomian gland conditions were evaluated. Results. The tear meniscus heights of the dry eye and normal groups were in normal range. Corneal fluorescein scores were significantly higher whereas no...
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Usefulness of Surgical Media Center as a Cataract Surgery Educational Tool.
Conclusions. Using SMC, it was possible to capture details of cataract surgery objectively. This recording device allows surgeons to review cataract surgery techniques and identify the cause of intraoperative complication and is a useful education tool for cataract surgery. PMID: 26881060 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus.
Conclusion. Cooperation of different mediators in tears all taking part in the complex pathomechanism of keratoconus was revealed. Our research verifies that inflammation plays a crucial role in the pathogenesis of KC. Additionally this study confirms the effect of bronchial asthma on keratoconus. PMID: 26881061 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Intraoperative Corneal Thickness Changes during Pulsed Accelerated Corneal Cross-Linking Using Isotonic Riboflavin with HPMC.
Authors: Sherif AM, El-Gheriany NA, Salah El-Din YM, Aly LS, Osman AA, Grentzelos MA, Kymionis GD Abstract Purpose. To evaluate corneal thickness changes during pulsed accelerated corneal cross-linking (CXL) for keratoconus using a new isotonic riboflavin formula. Methods. In this prospective, interventional, clinical study patients with grades 1-2 keratoconus (Amsler-Krumeich classification) underwent pulsed accelerated (30 mW/cm(2)) CXL after application of an isotonic riboflavin solution (0.1%) with HPMC for 10 minutes. Central corneal thickness (CCT) measurements were taken using ultrasound pachymetry be...
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Outcomes of 23-Gauge Vitrectomy Combined with Phacoemulsification, Panretinal Photocoagulation, and Trabeculectomy without Use of Anti-VEGF Agents for Neovascular Glaucoma with Vitreous Hemorrhage.
Authors: Yan H Abstract Purpose. To evaluate the outcomes of 23-gauge vitrectomy combined with phacoemulsification, PRP and trabeculectomy without use of anti-VEGF-agents for NVG. Methods. Eighteen eyes of 18 patients with NVG underwent 23-gauge vitrectomy combined with phacoemulsification, PRP and trabeculectomy without use of anti-VEGF agents. The preoperative BCVA ranged from light perception to 0.2. The preoperative IOP ranged from 38 mmHg to 64 mmHg with a mean of 54 ± 8 mmHg. The average follow-up time was 14.5 ± 3 months with a range from 11 to 24 months. Results. The posto...
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake.
Authors: Edwards JA Abstract Zeaxanthin is a nutritional carotenoid with a considerable amount of safety data based on regulatory studies, which form the basis of its safety evaluation. Subchronic OECD guideline studies with mice and rats receiving beadlet formulations of high purity synthetic zeaxanthin in the diet at dosages up to 1000 mg/kg body weight (bw)/day, and in dogs at over 400 mg/kg bw/day, produced no adverse effects or histopathological changes. In developmental toxicity studies, there was no evidence of fetal toxicity or teratogenicity in rats or rabbits at dosages up to 1000 or ...
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Comparison of Two Botulinum Neurotoxin A Injection Patterns with or without the Medial Lower Eyelid in the Treatment of Blepharospasm.
This study shows that the MLE-involved full injection pattern is a better choice for patients with BEB. It has longer-lasting effects in relieving BEB symptoms and better efficacy in reducing lacrimal drainage. Clinical Trials registration number is NCT02327728. PMID: 26885381 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 19, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research