Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Chest pain in children with familial Mediterranean fever
CONCLUSIONS: Patients with recurrent chest pain seem to have early onset symptoms, often are more likely to have family history, and have a higher disease severity. In addition, the presence of homozygous M694V mutation is more common in patients with chest pain.PMID:38204312 | DOI:10.24953/turkjped.2023.227 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - January 11, 2024 Category: Pediatrics Authors: Emine Nur Sunar-Yayla Pelin Esmeray Şenol Deniz Gezgin Y ıldırım O ğuz Söylemezoğlu Source Type: research
Synthesis, molecular docking analysis and < em > in vitro < /em > evaluation of new heterocyclic hybrids of 4-aza-podophyllotoxin as potent cytotoxic agents
RSC Adv. 2024 Jan 8;14(3):1838-1853. doi: 10.1039/d3ra07396c. eCollection 2024 Jan 3.ABSTRACTTwo different synthetic approaches to novel heterocyclic hybrid compounds of 4-azapodophyllotoxin were investigated. The obtained products were characterized by infrared spectroscopy, nuclear magnetic resonance spectroscopy, and high-resolution mass spectrometry. MTT protocol was then performed to examine the cytotoxic activity of these products against KB, HepG2, A549, MCF7, and Hek-293 cell lines. The cytotoxic assessment indicated that all products displayed moderate to high cytotoxicity against all tested cancer cell lines. The...
Source: Cancer Control - January 9, 2024 Category: Cancer & Oncology Authors: Ha Thanh Nguyen Ket Tran Van Hai Pham-The Julien Braire Phuong Hoang Thi Tuan Anh Nguyen Quynh Giang Nguyen Thi Tuyet Anh Dang Thi Giang Le-Nhat-Thuy Tu Anh Le Thi Doan Vu Ngoc Tuyen Nguyen Van Source Type: research
A case report of colchicine toxicity progressing from diarrhea to rhabdomyolysis: The probable role of interaction with ciprofloxacin
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 8, 2024 Category: Rheumatology Authors: Ahmet Murt Tags: LETTER TO THE EDITOR Source Type: research
Atherosclerotic three-layer nanomatrix vascular sheets for high-throughput therapeutic evaluation
Biomaterials. 2023 Dec 27;305:122450. doi: 10.1016/j.biomaterials.2023.122450. Online ahead of print.ABSTRACTIn vitro atherosclerosis models are essential to evaluate therapeutics before in vivo and clinical studies, but significant limitations remain, such as the lack of three-layer vascular architecture and limited atherosclerotic features. Moreover, no scalable 3D atherosclerosis model is available for making high-throughput assays for therapeutic evaluation. Herein, we report an in vitro 3D three-layer nanomatrix vascular sheet with critical atherosclerosis multi-features (VSA), including endothelial dysfunction, monoc...
Source: Biomaterials - January 3, 2024 Category: Materials Science Authors: Jun Chen Xixi Zhang Robbie Cross Yujin Ahn Gillian Huskin Will Evans Patrick Taejoon Hwang Jeong-A Kim Brigitta C Brott Hanjoong Jo Young-Sup Yoon Ho-Wook Jun Source Type: research
Colchicine and cardiovascular prevention
Eur J Intern Med. 2024 Jan 2:S0953-6205(23)00464-8. doi: 10.1016/j.ejim.2023.12.028. Online ahead of print.NO ABSTRACTPMID:38171936 | DOI:10.1016/j.ejim.2023.12.028 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - January 3, 2024 Category: Internal Medicine Authors: Alessia Alunno Francesco Carubbi Claudio Ferri Source Type: research
A systematic literature review of randomised controlled trials evaluating colchicine for cardiovascular prevention: There is an elephant in the room
CONCLUSION: Our results highlight the need to redefine the eligibility criteria as well as the reporting of results in future RCTs in order to minimise bias or previous exposure to COL and also obtain data that could be useful in rheumatology practice.PMID:38171935 | DOI:10.1016/j.ejim.2023.12.027 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - January 3, 2024 Category: Internal Medicine Authors: Alessia Alunno Francesco Carubbi Cecilia Martini Veronica Moronti Jessica Santilli Jan W Schoones Francesco Maria Mariani Evy Di Ruscio Piera Altieri Claudio Ferri Source Type: research
Atherosclerotic three-layer nanomatrix vascular sheets for high-throughput therapeutic evaluation
Biomaterials. 2023 Dec 27;305:122450. doi: 10.1016/j.biomaterials.2023.122450. Online ahead of print.ABSTRACTIn vitro atherosclerosis models are essential to evaluate therapeutics before in vivo and clinical studies, but significant limitations remain, such as the lack of three-layer vascular architecture and limited atherosclerotic features. Moreover, no scalable 3D atherosclerosis model is available for making high-throughput assays for therapeutic evaluation. Herein, we report an in vitro 3D three-layer nanomatrix vascular sheet with critical atherosclerosis multi-features (VSA), including endothelial dysfunction, monoc...
Source: Biomaterials - January 3, 2024 Category: Materials Science Authors: Jun Chen Xixi Zhang Robbie Cross Yujin Ahn Gillian Huskin Will Evans Patrick Taejoon Hwang Jeong-A Kim Brigitta C Brott Hanjoong Jo Young-Sup Yoon Ho-Wook Jun Source Type: research
Floral volatile composition of < em > Jasminum sambac < /em > variants developed through colchicine
Nat Prod Res. 2024 Jan 1:1-9. doi: 10.1080/14786419.2023.2298723. Online ahead of print.ABSTRACTJasmines are commercially grown for their fragrant flowers and essential oil. The present study investigates the composition of the volatile compounds from flowers of Jasminum sambac cv. Ramanthapuram Gundumalli and its variants that were evolved through colchicine. GC-MS analysis revealed that the flowers possessed major terpenes and sesquiterpenes such as Linalool, α-farnesene, germacrene-D, geranyl Linalool and D-Limonene as well as benzenoids (including benzyl acetate, benzyl alcohol and (Z)-Cinnamyl benzoate). The relative...
Source: Natural Product Research - January 2, 2024 Category: Biochemistry Authors: Vishnupandi S Ganga M Rajamani K Manonmani S Shobhana V G Manikanda Boopathi N Source Type: research
