Cluster analysis of long COVID symptoms for deciphering a syndrome and its long-term consequence
AbstractThe long-term symptoms of COVID-19 are the subject of public and scientific discussions. Understanding how those long COVID symptoms co-occur in clusters of syndromes may indicate the pathogenic mechanisms of long COVID. Our study objective was to cluster the different long COVID symptoms. We included persons who had a COVID-19 and assessed long-term symptoms (at least 4  weeks after first symptoms). Hierarchical clustering was applied to the symptoms as well as to the participants based on the Euclidean distanceh of the log-values of the answers on symptom severity. The distribution of clusters within our cohort ...
Source: Immunologic Research - April 16, 2024 Category: Allergy & Immunology Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | DOI:10.3346/jkms.2024.39.e120 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 10, 2024 Category: Biomedical Science Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 10, 2024 Category: Biomedical Science Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 10, 2024 Category: Biomedical Science Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 10, 2024 Category: Biomedical Science Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea
CONCLUSION: In Korea, during the COVID-19 pandemic, HCWs commonly suffered from mental health problems, including depression and anxiety. Regularly checking the physical and mental health problems of HCWs during the COVID-19 pandemic is crucial, and social support and strategy are needed to reduce the heavy workload and psychological distress of HCWs.PMID:38599597 | PMC:PMC11004773 | DOI:10.3346/jkms.2024.39.e120 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 10, 2024 Category: Biomedical Science Authors: Shinwon Lee Soyoon Hwang Ki Tae Kwon EunKyung Nam Un Sun Chung Shin-Woo Kim Hyun-Ha Chang Yoonjung Kim Sohyun Bae Ji-Yeon Shin Sang-Geun Bae Hyun Wook Ryoo Juhwan Jeong NamHee Oh So Hee Lee Yeonjae Kim Chang Kyung Kang Hye Yoon Park Jiho Park Se Yoon Park Source Type: research

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study
Accumulating evidence suggests that autonomic dysfunction and persistent systemic inflammation are common clinical features in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID. Howeve... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 10, 2024 Category: Research Authors: Joan Carles Domingo, Federica Battistini, Bego ña Cordobilla, Maria Cleofé Zaragozá, Ramón Sanmartin-Sentañes, Jose Alegre-Martin, Trinitat Cambras and Jesus Castro-Marrero Tags: Research Source Type: research

Viruses, Vol. 16, Pages 572: Herpesvirus Infection of Endothelial Cells as a Systemic Pathological Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
orius Understanding the pathophysiology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is critical for advancing treatment options. This review explores the novel hypothesis that a herpesvirus infection of endothelial cells (ECs) may underlie ME/CFS symptomatology. We review evidence linking herpesviruses to persistent EC infection and the implications for endothelial dysfunction, encompassing blood flow regulation, coagulation, and cognitive impairment—symptoms consistent with ME/CFS and Long COVID. This paper provides a synthesis of current research on herpesvirus latency and reactivatio...
Source: Viruses - April 8, 2024 Category: Virology Authors: Jean M. Nunes Douglas B. Kell Etheresia Pretorius Tags: Hypothesis Source Type: research

Imbalanced Brain Neurochemicals in long COVID and ME/CFS: A Preliminary Study using MRI
This study aims to measure brain neurochemical levels in long COVID and ME/CFS patients as well as healthy controls to investigate associations with severity measures. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 6, 2024 Category: General Medicine Authors: Kiran Thapaliya, Sonya Marshall-Gradisnik, Natalie Eaton-Fitch, Zeinab Eftekhari, Maira Inderyas, Leighton Barnden Source Type: research

Reactivation of herpesvirus type 6 and IgA/IgM-mediated responses to activin-A underpin long COVID, including affective symptoms and chronic fatigue syndrome
CONCLUSION: Reactivation of HHV-6, SARS-CoV-2 persistence, and autoimmune reactions to activin-A combined with activated immune-oxidative pathways play a major role in the pathophysiology of long COVID as well as the severity of its affective symptoms and CFS.PMID:38571295 | DOI:10.1017/neu.2024.10 (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - April 4, 2024 Category: Psychiatry Authors: Aristo Vojdani Abbas F Almulla Bo Zhou Hussein K Al-Hakeim Michael Maes Source Type: research