IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS)
DiscussionAlthough ME/CFS including PACS-CFS causes an immense individual, social, and economic burden, we lack efficient therapeutic options. The present study aims to investigate the efficacy of immunoadsorption and to contribute to the etiological understanding and establishment of diagnostic tools for ME/CFS.Trial registrationRegistration Number:NCT05710770. Registered on 02 February 2023. (Source: Trials)
Source: Trials - March 7, 2024 Category: Research Source Type: clinical trials

Rapamycin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Conditions: Myalgic Encephalomyelitis Interventions: Drug: Rapamycin Sponsors: Simmaron Research Inc.; Center For Complex Diseases-Seattle, WA; Sierra Internal Medicine, Incline Village, NV; Center for Complex Diseases- Palo Alto, CA Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Compound Xiwujia Granules Treat Chronic Fatigue Syndrome
Conditions: Chronic Fatigue Syndrome Interventions: Drug: Compound Xiwujia granule + Guipi granule Sponsors: Heilongjiang Quanle Pharmaceutical Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues
Conditions: Schizoaffective Disorder, Bipolar Type; Bipolar Disorder; ADHD - Combined Type; Dissociative Disorder; Stress Disorder; Dementia; Anxiety; Chronic Fatigue Syndrome Interventions: Combination Product: Decompartmentalization Framework; Dietary Supplement: Liquid Herbal TInctures; Other: Mental Imagery; Diagnostic Test: Clinical Yoga; Dietary Supplement: Dietary Supplements; Behavioral: Applied Relaxation; Behavioral: Pain Relaxation Techniques; Behavioral: Comprehensive Theocentric Psychological Assessment Sponsors: The Essence of Integrative Health and Medicine Practice Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials

Hydrogen Water Dosing Study for ME/CFS
Conditions: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Interventions: Dietary Supplement: Hydrogen water Sponsors: Stony Brook University; Natural Wellness Now Health Products Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials

The Use of Directed Probiotics in ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Conditions: ME/CFS; IBS - Irritable Bowel Syndrome Interventions: Drug: Floradapt Intensive GI; Other: Placebo Sponsors: Nova Southeastern University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials

Effect of Aerobic Training on Quality of Life in Elderly With Idiopathic Chronic Fatigue
Conditions: Chronic Idiopathic Fatigue Interventions: Other: Aerobic training Sponsors: Pharos University in Alexandria Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials

Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue
Conditions: Chronic Fatigue Syndrome Interventions: Other: APA program; Other: Active transcutaneous VNS; Other: Sham transcutaneous VNS Sponsors: Centre Hospitalier Universitaire de Saint Etienne Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Does the First Interview Matter: A Randomized Trial Comparing Life Stress Interview Versus a Standard Psychiatric Intake Interview for Patients With Functional Somatic Disorder
Conditions: Functional Somatic Syndrome; Functional Somatic Disorder; IBS - Irritable Bowel Syndrome; Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; Fibromyalgia; Somatic Symptom and Related Disorders; Functional Neurological Disorder; Somatic Symptom Disorder Interventions: Behavioral: Life stress interview according to EAET; Behavioral: Psychiatric interview according to " region stockholm - basutredning " Sponsors: Daniel Maroti; Wayne State University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials

A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis
Conditions: Myalgic Encephalomyelitis; Chronic Fatigue Syndrome Interventions: Other: Photobiomodulation therapy Sponsors: Quadram Institute Bioscience; University of East Anglia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
Conditions: Long COVID-19 Syndrome; Chronic Fatigue Syndrome Interventions: Drug: Fluvoxamine Maleate 100 MG; Drug: Placebo; Drug: Metformin Extended Release Oral Tablet Sponsors: Cardresearch Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials

POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS
Conditions: Chronic Fatigue Syndrome in Adolescence; Postural Orthostatic Tachycardia Syndrome; Orthostatic Intolerance Sponsors: Technical University of Munich; University Hospital, Aachen Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials

Munich ME/CFS Cohort Study
Condition:   Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3) Intervention:   Sponsors:   Technical University of Munich;   Helmholtz Munich, Munich;   German Cancer Research Center;   Charité University Hospital, Berlin, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 22, 2023 Category: Research Source Type: clinical trials