Integrated 'omics analysis for the gut microbiota response to moxibustion in a rat model of chronic fatigue syndrome
CONCLUSIONS: In this study, we demonstrated that moxibustion has an antifatigue-like effect. The results from the 16S rRNA gene sequencing and metabolomics analysis suggest that the therapeutic effects of moxibustion on CFS are related to the regulation of gut microorganisms and their metabolites. The increase in Bacteroides and decrease in LCA may be key targets for the moxibustion treatment of CFS.PMID:37946480 | PMC:PMC10623263 | DOI:10.19852/j.cnki.jtcm.20231018.004 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - November 10, 2023 Category: Complementary Medicine Authors: L I Chaoran Yang Yan Feng Chuwen L I Heng Q U Yuanyuan Wang Yulin Wang Delong Wang Qingyong Guo Jing Shi Tianyu Sun Xiaowei Wang Xue Hou Yunlong Sun Zhongren Yang Tiansong Source Type: research
Integrated 'omics analysis for the gut microbiota response to moxibustion in a rat model of chronic fatigue syndrome
CONCLUSIONS: In this study, we demonstrated that moxibustion has an antifatigue-like effect. The results from the 16S rRNA gene sequencing and metabolomics analysis suggest that the therapeutic effects of moxibustion on CFS are related to the regulation of gut microorganisms and their metabolites. The increase in Bacteroides and decrease in LCA may be key targets for the moxibustion treatment of CFS.PMID:37946480 | PMC:PMC10623263 | DOI:10.19852/j.cnki.jtcm.20231018.004 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - November 10, 2023 Category: Complementary Medicine Authors: L I Chaoran Yang Yan Feng Chuwen L I Heng Q U Yuanyuan Wang Yulin Wang Delong Wang Qingyong Guo Jing Shi Tianyu Sun Xiaowei Wang Xue Hou Yunlong Sun Zhongren Yang Tiansong Source Type: research
Case report: Rapid improvements of anorexia nervosa and probable myalgic encephalomyelitis/chronic fatigue syndrome upon metreleptin treatment during two dosing episodes
A comorbidity of anorexia nervosa (AN) and myalgic encephalomyelitis (ME/CSF) is uncommon. A 17 years-old male adolescent with possible onset of ME/CFS after an Epstein Barr Virus infection (EBV) and later onset of AN during a second period of weight loss was twice treated off-label with metreleptin for 15 and 11 days, respectively. As in previous cases, eating disorder specific cognitions and mood improved. Interestingly, fatigue and post-exertional muscle pain (P-EMP) improved, too. We discuss potential mechanisms. Treatment with metreleptin may prove beneficial in AN and in ME/CSF associated with substantial weight ...
Source: Frontiers in Psychiatry - November 9, 2023 Category: Psychiatry Source Type: research
How many in the U.S. are disabled? Proposed census changes would greatly decrease count
The U.S. Census Bureau may soon change the way one of its nationwide surveys asks about disability. But alarm bells are ringing for many researchers and activists, because the proposed change would dramatically decrease the official number of people in the United States who are considered disabled.
“Disabled people are already underserved,” says Scott Landes, a sociologist at Syracuse University who studies disability. Altering the way the Census Bureau gathers disability statistics, he argues, will generate “inaccurate information.” In
an 18 October letter
, he and other disability researchers and ...
Source: Science of Aging Knowledge Environment - November 8, 2023 Category: Geriatrics Source Type: research
Does the effect of cognitive behavior therapy for chronic fatigue syndrome (ME/CFS) vary by patient characteristics? A systematic review and individual patient data meta-analysis
Psychol Med. 2023 Nov 6:1-10. doi: 10.1017/S0033291723003148. Online ahead of print.ABSTRACTDebate is ongoing on the efficacy of cognitive behavior therapy (CBT) for myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS). With an individual patient data (IPD) meta-analysis we investigated whether the effect of CBT varied by patient characteristics. These included post-exertional malaise (PEM), a central feature of ME/CFS according to many. We searched for randomized controlled trials similar with respect to comparison condition, outcomes and treatment-protocol. Moderation on fatigue severity (Checklist Individual S...
Source: Psychological Medicine - November 6, 2023 Category: Psychiatry Authors: T A Kuut L M Buffart A M J Braamse I Csorba G Bleijenberg P Nieuwkerk R Moss-Morris F M üller H Knoop Source Type: research
