Post-exertional malaise in daily life and experimental exercise models in patients with myalgic encephalomyelitis/chronic fatigue syndrome
Post-exertional malaise (PEM) is commonly recognized as a hallmark of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and is often used as one of several criteria for diagnosing ME/CFS. In this perspective paper we want to reflect on how PEM is understood, assessed, and evaluated in scientific literature, and to identify topics to be addressed in future research. Studies show that patients use a wide variety of words and concepts to label their experience of PEM in everyday life, and they report physical or mental exertions as triggers of PEM. They also report that PEM may have an immediate or delayed onset and...
Source: Frontiers in Physiology - December 4, 2023 Category: Physiology Source Type: research
Farmers ’ Mental Health: The Mediating Role of Chronic Fatigue
. (Source: Journal of Agromedicine)
Source: Journal of Agromedicine - December 4, 2023 Category: Environmental Health Authors: Didier DolbecPhilippe DubreuilLaetitia Larouchea Department of Psychology, Faculty of Arts and Humanities, Universit é de Sherbrooke, Sherbrooke, Canadab Department of Human Resources Management, Université du Québec à Trois-Rivières, Trois-Rivières Source Type: research
Sex differences in vascular endothelial function related to acute and long COVID-19
Vascul Pharmacol. 2023 Dec 1:107250. doi: 10.1016/j.vph.2023.107250. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been at the forefront of health sciences research since its emergence in China in 2019 that quickly led to a global pandemic. As a result of this research, and the large numbers of infected patients globally, there were rapid enhancements made in our understanding of Coronavirus disease 2019 (COVID-19) pathology, including its role in the development of uncontrolled immune responses and its link to the development of endotheliitis and endothelial dysfu...
Source: Vascular Pharmacology - December 3, 2023 Category: Drugs & Pharmacology Authors: Kitselman A Kayla J érôme Bédard-Matteau Simon Rousseau Reza Tabrizchi Daneshtalab Noriko Source Type: research
Sex differences in vascular endothelial function related to acute and long COVID-19
Vascul Pharmacol. 2023 Dec 1:107250. doi: 10.1016/j.vph.2023.107250. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been at the forefront of health sciences research since its emergence in China in 2019 that quickly led to a global pandemic. As a result of this research, and the large numbers of infected patients globally, there were rapid enhancements made in our understanding of Coronavirus disease 2019 (COVID-19) pathology, including its role in the development of uncontrolled immune responses and its link to the development of endotheliitis and endothelial dysfu...
Source: Vascular Pharmacology - December 3, 2023 Category: Drugs & Pharmacology Authors: Kitselman A Kayla J érôme Bédard-Matteau Simon Rousseau Reza Tabrizchi Daneshtalab Noriko Source Type: research
Focus on post-exertional malaise when approaching ME/CFS in specialist healthcare improves satisfaction and reduces deterioration
This study aims to evaluate to what extent ME/CFS patients experienced focus on PEM in specialist healthcare practice and its significance for outcome and care quality.MethodsData from two online cross-sectional surveys covering specialist healthcare services for ME/CFS patients at rehabilitation institutes in Norway and two regional hospitals, respectively, were analyzed. Evaluations of 788 rehabilitation stays, 86 hospital consultations, and 89 hospital interventions were included. Logistic regression models and Mann–Whitney U-tests were used to quantify the impact of addressing PEM on health and functioning, care sati...
Source: Frontiers in Neurology - December 1, 2023 Category: Neurology Source Type: research
Three-month creatine supplementation ameliorates clinical features in long COVID patients
Rationale: Several previous studies suggested favorable effects of creatine in chronic fatigue syndrome and similar conditions yet limited information is currently available whether medium-term creatine supplementation affects patient- and clinician-reported outcomes in long COVID. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: M. Ranisavljev, J. Slankamenac, N. Todorovic, J. Ostojic, V. Stajer, S.M. Ostojic Source Type: research
Synchronize+, a multicomponent group intervention improving the adherence to mediterranean diet of persons with fibromyalgia and chronic fatigue syndrome
Rationale: Fibromyalgia (FM) and chronic fatigue (CFS) are syndromes of complex management. The health benefits of the SYNCHRONIZE + intervention based on nutrition, chronobiology and physical exercise are being studied. A first-step was to evaluate its effectiveness in improving the adherence to Mediterranean Diet (MedDiet). (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: N. Carrasco-Querol, N. Bueno Hern ández, E. Castro Blanco, A.Q. Gonçalves, G. González Serra, I. Fusté Anguera, R. Caballol Angelats, A. Vila-Martí, M. Dalmau Llorca, J. Fernández.Sáez, C. Aguilar Martín Source Type: research
EE238 Cost-Effectiveness of Online Cognitive Behavioral Therapy for Children with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) Compared to Online Activity Management: FITNET-NHS Trial Findings
Most children in the UK with chronic fatigue syndrome/ myalgic encephalomyelitis (CFS /ME) do not have local access to specialist support. We assessed the cost-effectiveness, from a UK healthcare perspective, of delivering online cognitive behavioral therapy (CBT) for children with CFS/ME and their parents, compared to online activity management (AM). In addition, we conducted subgroup analyses for children with and without mild/moderate comorbid anxiety/depression. We also assessed cost-effectiveness from a wider perspective incorporating parental/carer and educational costs. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M. Cochrane, A. Annaw, B. Shirkey, C. Metcalfe, G. Treneman-Evans, E. Crawley, W. Hollingworth Source Type: research
Case report: Recurrent cervical spinal stenosis masquerading as myalgic encephalomyelitis/chronic fatigue syndrome with orthostatic intolerance
ConclusionThis recapitulation of the outcomes after surgical management of cervical stenosis provides further evidence in support of the hypothesis that cervical spinal stenosis can exacerbate pre-existing or cause new orthostatic intolerance and ME/CFS. Especially for those with refractory symptoms and neurological signs, surgical interventions may offer relief for selected patients with this complex condition. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - November 30, 2023 Category: Neurology Source Type: research
DNA Methylation Changes in Blood Cells of Fibromyalgia and Chronic Fatigue Syndrome Patients
(Source: Journal of Pain Research)
Source: Journal of Pain Research - November 29, 2023 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
