Affinity of β-Lactam Antibiotics for Neisseria gonorrhoeae Penicillin-Binding Protein 2 Having Wild, Cefixime-Reduced-Susceptible, and Cephalosporin (Ceftriaxone)-Resistant penA Alleles
Microbial Drug Resistance, Ahead of Print. (Source: Microbial Drug Resistance)
Source: Microbial Drug Resistance - January 12, 2024 Category: Microbiology Authors: Yoshiki Hiyama Soh Yamamoto Toyotaka Sato Noriko Ogasawara Naoya Masumori Satoshi Takahashi Shin-ichi Yokota Source Type: research

Comorbidity of Mitral Valve Stenosis with Influenza in Pregnancy, A Case Report
Adv Biomed Res. 2023 Nov 29;12:252. doi: 10.4103/abr.abr_104_23. eCollection 2023.ABSTRACTIn this case, a 44-year-old pregnant woman at a gestational age of 28 weeks and 6 days with symptoms of cold, shortness of breath, and cough since a week ago. She had received remdesivir ampoule, Tamiflu tablet, meropenem and linezolid, and dexamethasone. She received oxygen through a 14-liter reservoir bag mask and hydrocortisone, heparin, and ceftriaxone. Nine hours after hospitalization, the patient suffered a cardiorespiratory arrest, resuscitation was performed, and the patient was intubated. Emergency cesarean section was done i...
Source: Biomed Res - January 9, 2024 Category: Research Authors: Minoo Movahedi Maryam Goharian Azita Kabiri Shadi Zamansaraei Source Type: research

Predictors and patterns of empirical antibiotic therapy and associated outcomes in COVID-19 patients: a retrospective study in a tertiary care facility in South India
CONCLUSION: The study identified predictors for initiating empirical antibacterial therapy in our setting and highlighted the need for rational antibiotic therapy.PMID:38189087 | DOI:10.1080/14787210.2024.2303019 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 8, 2024 Category: Infectious Diseases Authors: Lipin Lukose Gursimran Kaur Mohammed Asif M Gail Ann Abraham Kanav Khera Subeesh K Viswam Ronald L Castelino Shubhada Karanth Chandrashekar Udyavara Kudru Muralidhar Varma Sonal Sekhar Miraj Source Type: research

Occurrence and characterization of β-lactamase-producing bacteria in biomedical wastewater and in silico enhancement of antibiotic efficacy
This study focused on the analysis of β-lactamase-producing pathogenic bacteria within untreated biomedical wastewater originating from various hospitals in Dhaka City, Bangladesh, as well as in silico evaluation and structural activity relationship mentioned antibiotics were evaluated. In silico drug design techniques were applied to identify the relationship with how the functional group impacts the binding energy. Out of the 184 isolates obtained from well-established hospital sewage discharge points in Dhaka, 89 were identified as β-lactamase positive. These bacteria were subjected to antimicrobial susceptibility tes...
Source: Frontiers in Microbiology - January 8, 2024 Category: Microbiology Source Type: research