Whipple's disease of the respiratory system: A case report
Exp Ther Med. 2024 Feb 7;27(4):133. doi: 10.3892/etm.2024.12421. eCollection 2024 Apr.ABSTRACTWhipple's disease (WD) is a multiple-system chronic disease caused by Tropheryma whipplei (T. whipplei) infection. The present study describes 3 cases of WD with clinical manifestations of cough, chest pain, headache, dyspnea, sputum, joint pain, abdominal pain, diarrhea and weight loss. Chest computed tomography (CT) showed signs of plaques, nodules and pleural thickening; and bronchoscopic alveolar lavage fluid metagenomic-sequencing indicated that it was T. whipplei. One patient was treated with meropenem as the starting regime...
Source: Experimental and Therapeutic Medicine - February 28, 2024 Category: General Medicine Authors: Yue Deng Hongmei Zhang Junyu Lu Zhiyu Zhou Ting Zhang Xuerong Cui Source Type: research

Rapid determination of antimicrobial susceptibility of Gram-negative bacteria from clinical blood cultures using a scattered light-integrated collection device
Conclusion. SLIC has the capacity to provide accurate AST 1 day earlier from flagged positive blood cultures than SOC. This significant time saving could accelerate time to optimal antimicrobial therapy, improving antimicrobial stewardship and management of BSIs.PMID:38415707 | DOI:10.1099/jmm.0.001812 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 28, 2024 Category: Microbiology Authors: Kerry Falconer Robert Hammond Benjamin J Parcell Stephen H Gillespie Source Type: research

Whipple's disease of the respiratory system: A case report
Exp Ther Med. 2024 Feb 7;27(4):133. doi: 10.3892/etm.2024.12421. eCollection 2024 Apr.ABSTRACTWhipple's disease (WD) is a multiple-system chronic disease caused by Tropheryma whipplei (T. whipplei) infection. The present study describes 3 cases of WD with clinical manifestations of cough, chest pain, headache, dyspnea, sputum, joint pain, abdominal pain, diarrhea and weight loss. Chest computed tomography (CT) showed signs of plaques, nodules and pleural thickening; and bronchoscopic alveolar lavage fluid metagenomic-sequencing indicated that it was T. whipplei. One patient was treated with meropenem as the starting regime...
Source: Experimental and Therapeutic Medicine - February 28, 2024 Category: General Medicine Authors: Yue Deng Hongmei Zhang Junyu Lu Zhiyu Zhou Ting Zhang Xuerong Cui Source Type: research

Rapid determination of antimicrobial susceptibility of Gram-negative bacteria from clinical blood cultures using a scattered light-integrated collection device
Conclusion. SLIC has the capacity to provide accurate AST 1 day earlier from flagged positive blood cultures than SOC. This significant time saving could accelerate time to optimal antimicrobial therapy, improving antimicrobial stewardship and management of BSIs.PMID:38415707 | DOI:10.1099/jmm.0.001812 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 28, 2024 Category: Microbiology Authors: Kerry Falconer Robert Hammond Benjamin J Parcell Stephen H Gillespie Source Type: research

Whipple's disease of the respiratory system: A case report
Exp Ther Med. 2024 Feb 7;27(4):133. doi: 10.3892/etm.2024.12421. eCollection 2024 Apr.ABSTRACTWhipple's disease (WD) is a multiple-system chronic disease caused by Tropheryma whipplei (T. whipplei) infection. The present study describes 3 cases of WD with clinical manifestations of cough, chest pain, headache, dyspnea, sputum, joint pain, abdominal pain, diarrhea and weight loss. Chest computed tomography (CT) showed signs of plaques, nodules and pleural thickening; and bronchoscopic alveolar lavage fluid metagenomic-sequencing indicated that it was T. whipplei. One patient was treated with meropenem as the starting regime...
Source: Experimental and Therapeutic Medicine - February 28, 2024 Category: General Medicine Authors: Yue Deng Hongmei Zhang Junyu Lu Zhiyu Zhou Ting Zhang Xuerong Cui Source Type: research