General anesthesia vs procedural sedation for failed NeuroThrombectomy undergoing rescue stenting: intention to treat analysis
Conclusions Non-GA seems to be a safe and effective anesthesia strategy for patients undergoing rescue ICAS after failed MT. Larger prospective studies are warranted for more concrete evidence. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - November 2, 2023 Category: Neurosurgery Authors: Mohammaden, M. H., Haussen, D. C., Al-Bayati, A. R., Hassan, A. E., Tekle, W., Fifi, J. T., Matsoukas, S., Kuybu, O., Gross, B. A., Lang, M., Narayanan, S., Cortez, G. M., Hanel, R. A., Aghaebrahim, A., Sauvageau, E., Farooqui, M., Ortega-Gutierrez, S., Z Tags: Ischemic stroke Source Type: research

Ultrasound-Guided Periadventitial Administration of Rapamycin-Fibrin Glue Attenuates Neointimal Hyperplasia in the Rat Carotid Artery Injury Model
CONCLUSION: Periadventitial delivery of RPM-FG contributed to inhibiting IH in the rat carotid artery injury model without compromising re-endothelialization. Additionally, FG provided a promising platform for the future development of a safe, effective, and minimally invasive perivascular drug delivery method to treat vascular disease.PMID:37852309 | DOI:10.1016/j.ejps.2023.106610 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - October 18, 2023 Category: Drugs & Pharmacology Authors: Zhentao Qiao Fuhang Wang Dongjian Han Yuansong Zhuang Qingjiao Jiang Yi Zhang Miaomiao Liu Quanxu An Zhiwei Wang Deliang Shen Source Type: research

Ultrasound-Guided Periadventitial Administration of Rapamycin-Fibrin Glue Attenuates Neointimal Hyperplasia in the Rat Carotid Artery Injury Model
CONCLUSION: Periadventitial delivery of RPM-FG contributed to inhibiting IH in the rat carotid artery injury model without compromising re-endothelialization. Additionally, FG provided a promising platform for the future development of a safe, effective, and minimally invasive perivascular drug delivery method to treat vascular disease.PMID:37852309 | DOI:10.1016/j.ejps.2023.106610 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - October 18, 2023 Category: Drugs & Pharmacology Authors: Zhentao Qiao Fuhang Wang Dongjian Han Yuansong Zhuang Qingjiao Jiang Yi Zhang Miaomiao Liu Quanxu An Zhiwei Wang Deliang Shen Source Type: research

Transradial intra-aortic catheter looping in the angioplasty of severe intracranial symptomatic arteriosclerotic diseases
ConclusionIntra-aortic guiding catheter looping via transradial access for endovascular angioplasty of SISOLAs is technically safe, feasible, and effective, especially when the transfemoral artery approach is difficult or impossible to undertake. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - October 13, 2023 Category: Neurology Source Type: research

Application of SF-36 Health Status Survey in Patients with Arterial Hypertension
CONCLUSIONS: AH, especially with hemodynamically significant atherosclerosis of the coronary arteries are the predictors for QOL worsening in cardiological patients, mostly in men. Using of the international questionnaire "SF-36 Health Status Survey" is advisable to assess the QOL in patients with cardiovascular diseases. In this sense, the interaction of a cardiologist and a psychotherapist is appropriate and justified for the most optimal management of a patient with this pathology.PMID:37800248 (Source: Atherosclerosis)
Source: Atherosclerosis - October 6, 2023 Category: Cardiology Authors: Olga A Germanova Yulia Yu Vukolova Anna Strelnik Olga Izmailova Irina V Gubareva Giuseppe Galati Source Type: research

Application of SF-36 Health Status Survey in Patients with Arterial Hypertension
CONCLUSIONS: AH, especially with hemodynamically significant atherosclerosis of the coronary arteries are the predictors for QOL worsening in cardiological patients, mostly in men. Using of the international questionnaire "SF-36 Health Status Survey" is advisable to assess the QOL in patients with cardiovascular diseases. In this sense, the interaction of a cardiologist and a psychotherapist is appropriate and justified for the most optimal management of a patient with this pathology.PMID:37800248 (Source: Atherosclerosis)
Source: Atherosclerosis - October 6, 2023 Category: Cardiology Authors: Olga A Germanova Yulia Yu Vukolova Anna Strelnik Olga Izmailova Irina V Gubareva Giuseppe Galati Source Type: research

Purtscher-like retinopathy following carotid angioplasty and stenting in the treatment of severe carotid stenosis
We present a case of Purtscher-like retinopathy (PLR) following carotid angioplasty and stenting (CAS). A 56-year-old man with a history of severe stenosis of the left carotid artery and treated by CAS refers acute and painless visual loss on the left eye (OS) 48 h after the procedure. Funduscopic examination showed cotton wool spots and intraretinal hemorrhages confined to the peripapillary and posterior pole of the OS. The optical coherence tomography (OCT) showed retinal thickening and hyperintense lesions in the inner nuclear layer retina.PMID:37792548 | DOI:10.1177/11206721231204632 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - October 4, 2023 Category: Opthalmology Authors: M G Solaz-Ruiz N Sevilla-Redoreda C Cauto-Picazo L Azor ín-Pérez C Neira-Fonseca E Espa ña-Gregori Source Type: research

Purtscher-like retinopathy following carotid angioplasty and stenting in the treatment of severe carotid stenosis
We present a case of Purtscher-like retinopathy (PLR) following carotid angioplasty and stenting (CAS). A 56-year-old man with a history of severe stenosis of the left carotid artery and treated by CAS refers acute and painless visual loss on the left eye (OS) 48 h after the procedure. Funduscopic examination showed cotton wool spots and intraretinal hemorrhages confined to the peripapillary and posterior pole of the OS. The optical coherence tomography (OCT) showed retinal thickening and hyperintense lesions in the inner nuclear layer retina.PMID:37792548 | DOI:10.1177/11206721231204632 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - October 4, 2023 Category: Opthalmology Authors: M G Solaz-Ruiz N Sevilla-Redoreda C Cauto-Picazo L Azor ín-Pérez C Neira-Fonseca E Espa ña-Gregori Source Type: research

Transradial Carotid Intervention: Technology on the Rise, Single-center Retrospective Review
This study aimed to compare the early results of transradial carotid angioplasty and stent placement (TR-CAS) to transfemoral carotid artery angioplasty and stent placement (TF-CAS) in both asymptomatic and symptomatic patients from 2020 to 2023. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - September 20, 2023 Category: Surgery Authors: Lakshmikumar Pillai, Rachelle Sapp Tags: Carotid Artery Interventions Source Type: research

Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling
In this study we investigated the effect of MYDGF to postinjury neointimal formation and the underlying mechanisms. Rat carotid arteries balloon-injured model was established. We found that plasma MYDGF content and the level of MYDGF in injured arteries were significantly decreased after balloon injury. Local application of exogenous MYDGF (50 μg/mL) around the injured vessel during balloon injury markedly ameliorated the development of neointimal formation evidenced by relieving the narrow endovascular diameter, improving hemodynamics, and reducing collagen deposition. In addition, local application of MYDGF inhibited VS...
Source: Acta Pharmacologica Sinica - September 19, 2023 Category: Drugs & Pharmacology Authors: Shuang Yang Hou-Wei Li Jia-Ying Tian Zheng-Kai Wang Yi Chen Ting-Ting Zhan Chun-Yue Ma Min Feng Shi-Feng Cao Yu Zhao Xue Li Jing Ren Qian Liu Lu-Ying Jin Zhi-Qi Wang Wen-Yu Jiang Yi-Xiu Zhao Yan Zhang Xue Liu Source Type: research

Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling
In this study we investigated the effect of MYDGF to postinjury neointimal formation and the underlying mechanisms. Rat carotid arteries balloon-injured model was established. We found that plasma MYDGF content and the level of MYDGF in injured arteries were significantly decreased after balloon injury. Local application of exogenous MYDGF (50 μg/mL) around the injured vessel during balloon injury markedly ameliorated the development of neointimal formation evidenced by relieving the narrow endovascular diameter, improving hemodynamics, and reducing collagen deposition. In addition, local application of MYDGF inhibited VS...
Source: Acta Pharmacologica Sinica - September 19, 2023 Category: Drugs & Pharmacology Authors: Shuang Yang Hou-Wei Li Jia-Ying Tian Zheng-Kai Wang Yi Chen Ting-Ting Zhan Chun-Yue Ma Min Feng Shi-Feng Cao Yu Zhao Xue Li Jing Ren Qian Liu Lu-Ying Jin Zhi-Qi Wang Wen-Yu Jiang Yi-Xiu Zhao Yan Zhang Xue Liu Source Type: research

Stent retrieval for free-floating thrombus attached to carotid artery stenosis: A report of two cases
CONCLUSION: In cases of carotid artery stenosis with FFT, it is technically possible to retrieve a thrombus with a stent retriever. Although thrombus removal may help reduce the risk of ischemic complications in a series of urgent CAS procedures, there are concerns such as mechanical irritation to the carotid artery plaque, and its indications and alternative treatments should be carefully considered.PMID:37680937 | PMC:PMC10481818 | DOI:10.25259/SNI_513_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - September 8, 2023 Category: Neurosurgery Authors: Yuki Yamamoto Nobuaki Yamamoto Tomohiro Matsuda Kazutaka Kuroda Izumi Yamaguchi Shu Sogabe Masaaki Korai Kenji Shimada Yasuhisa Kanematsu Yasushi Takagi Yuishin Izumi Source Type: research