Bypass and other modified reconstruction techniques for 'challenging' carotid cases: A comparison with conventional endarterectomy
CONCLUSIONS: Patients who underwent ICA revascularization with MCAR showed risks of perioperative death, major or minor stroke (<2%), reintervention rates and carotid restenosis rates that are comparable with PCEA or ECEA groups. Nevertheless, the MCAR group showed a significantly higher rate of global central neurological complications (considering together TIA, minor stroke and major stroke) than patients treated with standard CEA. MCAR techniques appear to be effective alternatives to standard CEAs, with an acceptable surgical risk. However, these should be performed mainly in selected cases, for example, in complex ...
Source: Vascular - May 12, 2023 Category: Surgery Authors: Andrea Xodo Federico Barbui Alessandro Desole Fabio Pilon Massimiliano Zaramella Domenico Milite Source Type: research

Resveratrol inhibits restenosis through suppressing proliferation, migration and trans-differentiation of vascular adventitia fibroblasts via activating SIRT1
CONCLUSION: Above results indicated RSV inhibited restenosis after balloon angioplasty through suppressing proliferation, migration and trans-differentiation of VAFs via regulating SIRT1- TGF-β1-SMAD3-NOX4 to decrease ROS.PMID:37151061 | DOI:10.2174/0929867330666230505161041 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - May 8, 2023 Category: Chemistry Authors: Mengyun Li Lan Luo Ying Xiong Fuyu Wang Yun Xia Zongze Zhang Jianjuan Ke Source Type: research

Resveratrol inhibits restenosis through suppressing proliferation, migration and trans-differentiation of vascular adventitia fibroblasts via activating SIRT1
CONCLUSION: Above results indicated RSV inhibited restenosis after balloon angioplasty through suppressing proliferation, migration and trans-differentiation of VAFs via regulating SIRT1- TGF-β1-SMAD3-NOX4 to decrease ROS.PMID:37151061 | DOI:10.2174/0929867330666230505161041 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - May 8, 2023 Category: Chemistry Authors: Mengyun Li Lan Luo Ying Xiong Fuyu Wang Yun Xia Zongze Zhang Jianjuan Ke Source Type: research

Long Term Follow Up of Dacron Versus Bovine Pericardium For Carotid Endarterectomy With Patch Angioplasty: a Retrospective Cohort Study
Objective: Patch angioplasty during carotid endarterectomy (CEA) is commonly used to treat carotid artery stenosis. Various patch materials are available, including venous, Dacron, bovine pericardium, and polytetrafluoroethylene. However, the choice of which patch to use is still a matter of debate. Autologous venous material has disadvantages such as wound related problems and a prolonged intervention time. This is due to the harvesting of the vein. These limitations can be bypassed when synthetic or biological patches are used, which are immediately available. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: D. Liesker, B. Gareb, R. Looman, C. Zeebregts, B. Saleem Source Type: research

History of Carotid Artery Reconstruction around the World and in Japan
Neurol Med Chir (Tokyo). 2023 Apr 20. doi: 10.2176/jns-nmc.2022-0362. Online ahead of print.ABSTRACTSince ancient times, physicians have been aware of correlations between the carotid artery and consciousness; however, carotid stenosis was only recently identified as the cause of atherothrombotic ischemic stroke. In 1658, Wepfer described the first suggestion of a link between symptoms of cerebral arterial insufficiency and carotid pathology. In 1951, Fisher reported details of the symptoms and pathological findings and emphasized that cervical atheromatous lesions induced cerebral infarction with various symptoms. The beg...
Source: Neurologia Medico-Chirurgica - April 21, 2023 Category: Neurosurgery Authors: Masaaki Uno Source Type: research