Ultrasound examination of the carotid artery for improved prediction of cardiovascular events and the effect of statin treatment in advanced atherosclerosis : An observational study
CONCLUSION: The prediction of cardiovascular events was better with plaque burden measurements than with the PROCAM score. Treatment with statins in subjects with advanced carotid atherosclerosis (types III-IV b findings on ultrasound) significantly improved the prognosis in a nonrandomized observational study.PMID:37402837 | DOI:10.1007/s00059-023-05197-z (Source: Herz)
Source: Herz - July 4, 2023 Category: Cardiology Authors: Ansgar Adams Waldemar Bojara Michel Romanens Source Type: research
Imaging diagnosis of intracranial atherosclerosis stenosis-related large vessel occlusion before and during endovascular therapy
We describe the diagnosis of intracranial atherosclerotic stenosis-related large vessel occlusion from the perspectives of “thrombus imaging,” “perfusion,” and “occlusion margin.” (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - June 21, 2023 Category: Neurology Source Type: research
Prospective multicenter online testing of the carotid endarterectomy risk stratification calculator carotidscore.ru
ConclusionThe use of CarotidSCORE (carotidscore.ru) allows for the identification of high-risk patients, enabling clinicians to opt for CAS instead of CEA and reduce the incidence of complications. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - June 14, 2023 Category: Cardiovascular & Thoracic Surgery Source Type: research
Investigation of Combined Carotid Endarterectomy and Coronary Artery Bypass Graft Surgery Outcomes and Adverse Event Risk Factors in the Vascular Quality Initiative
CONCLUSIONS: Combined CEA and CABG provides excellent long-term mortality prevention in patients with co-existing severe coronary and carotid atherosclerosis. Simultaneous CEA and CABG provides equivalent stroke prevention and long-term survival to both a cohort of patients undergoing coronary revascularization within 5 years of CEA and patients undergoing isolated CEA or CABG in the literature. The two most impactful modifiable risk factors towards long-term stroke and mortality prevention for patients undergoing simultaneous CEA-CABG are patch placement at CEA site and adherence to statin medication therapy.PMID:37303074...
Source: Atherosclerosis - June 11, 2023 Category: Cardiology Authors: Ashley Penton Jonathan Lin Grant Kolde Matthew DeJong Matthew Blecha Source Type: research
Temporal Trends and Contemporary Regional Variation in Management of Patients Undergoing Carotid Endarterectomy
CONCLUSIONS: Prior studies and societal initiatives on CEA documenting the beneficial effects of patch angioplasty, protamine use at surgery, smoking cessation, antiplatelet utilization and statin compliance have positively impacted adherence to these measures over time. In the modern 2016-2022 era the widest regional variation is noted in patch placement, protamine utilization and discharge medications allowing individual geographic areas to identify areas for potential improvement via internal VQI administrative feedback.PMID:37303024 | DOI:10.1177/15385744231183750 (Source: Atherosclerosis)
Source: Atherosclerosis - June 11, 2023 Category: Cardiology Authors: Ashley Penton Robert Kelly Linda Le Matthew Blecha Source Type: research
Hyperacute stenting and angioplasty for acute extracranial non-tandem internal carotid artery strokes within the first 48 h: A 20-year experience and a systematic review and meta-analysis
CONCLUSION: Stenting and angioplasty for acute cervical ICA occlusive strokes during the hyperacute phase can be performed successfully with favorable clinical outcomes and an acceptable recanalization rate.PMID:37218164 | DOI:10.1177/15910199231164510 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - May 23, 2023 Category: Radiology Authors: Ammad A Baig Pui Man Rosalind Lai Ryan C Turner Brianna M Donnelly Cathleen C Kuo Jaims Lim Kunal P Raygor Mehdi Bouslama Shefalika Prasad Najya Fayyaz Kenneth V Snyder Jason M Davies Adnan H Siddiqui Elad I Levy Source Type: research
Carotid Artery Remodeling After Modified Eversion Carotid Endarterectomy
Modified eversion carotid endarterectomy (meCEA) is an alternative to classical patch angioplasty or eversion. An meCEA involves everting the carotid plaque through a longitudinal incision over the common carotid artery without transecting the internal carotid artery (ICA). Those who advocate patch angioplasty cite the propensity of luminal narrowing from the procedure or restenosis as a reason to avoid primary repair. We seek to objectively quantify the outcome of the carotid artery after primary repair of the longitudinal incision employed in this technique. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - May 23, 2023 Category: Surgery Authors: Besher Tolaymat, Bruce L. Tjaden, Katherine K. McMackin, Arjun Kumar, Philip M. Batista, Jeffrey Carpenter, Joseph V. Lombardi Tags: Interactive Poster Session Source Type: research
Systemic Amlexanox, a TBK1/IKK ε Inhibitor, Decreases IFN-γ-mediated Phosphorylation of STAT1-Blocking Atherogenic Signaling and Preventing Intimal Hyperplasia After Carotid Artery Balloon Angioplasty
Peripheral arterial disease affects>230 million people worldwide and causes significant morbidity. Venous interposition bypass grafts or endovascular balloon angioplasty with stenting are the cornerstone of current revascularization procedures. Unfortunately, 30% to 50% of venous interposition bypass grafts fail within 5 years, and 20% to 30% of angioplasties fail within one year due to intimal hyperplasia (IH). Given the implication of atherogenic IFN-γ signaling in driving IH, we investigated the impact of Amlexanox, a small molecule inhibitor of TBK1/IKKε and potential modulator of IFN-γ signaling, on IH in a rat m...
Source: Journal of Vascular Surgery - May 23, 2023 Category: Surgery Authors: Phillip G. Brennan, Jacqueline Wade, Erin McIntosh, Tarek Aridi, Nyah Patel, Mauricio Contreras, Cleide Angolano, Christiane Ferran Tags: Poster Competition Source Type: research
Bypass and other modified reconstruction techniques for 'challenging' carotid cases: A comparison with conventional endarterectomy
CONCLUSIONS: Patients who underwent ICA revascularization with MCAR showed risks of perioperative death, major or minor stroke (<2%), reintervention rates and carotid restenosis rates that are comparable with PCEA or ECEA groups. Nevertheless, the MCAR group showed a significantly higher rate of global central neurological complications (considering together TIA, minor stroke and major stroke) than patients treated with standard CEA. MCAR techniques appear to be effective alternatives to standard CEAs, with an acceptable surgical risk. However, these should be performed mainly in selected cases, for example, in complex ...
Source: Vascular - May 12, 2023 Category: Surgery Authors: Andrea Xodo Federico Barbui Alessandro Desole Fabio Pilon Massimiliano Zaramella Domenico Milite Source Type: research
Bypass and other modified reconstruction techniques for 'challenging' carotid cases: A comparison with conventional endarterectomy
CONCLUSIONS: Patients who underwent ICA revascularization with MCAR showed risks of perioperative death, major or minor stroke (<2%), reintervention rates and carotid restenosis rates that are comparable with PCEA or ECEA groups. Nevertheless, the MCAR group showed a significantly higher rate of global central neurological complications (considering together TIA, minor stroke and major stroke) than patients treated with standard CEA. MCAR techniques appear to be effective alternatives to standard CEAs, with an acceptable surgical risk. However, these should be performed mainly in selected cases, for example, in complex ...
Source: Vascular - May 12, 2023 Category: Surgery Authors: Andrea Xodo Federico Barbui Alessandro Desole Fabio Pilon Massimiliano Zaramella Domenico Milite Source Type: research
