Comparative analysis of stenting for carotid web and atherosclerotic disease
CONCLUSION: Stenting for CaW was found to be technically simpler than CAD and not to confer increased risk of baroreceptor dysregulation. Intimal hyperplasia was uncommon in CaW cases.PMID:37563917 | DOI:10.1177/15910199231188856 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - August 11, 2023 Category: Radiology Authors: Ehizele M Osehobo Raul G Nogueira Nilushi Karunamuni Sitara Koneru Achanti David Landzberg Qasem Al Shaer Jonathan A Grossberg Alhamza Al-Bayati Diogo C Haussen Source Type: research

Comparative analysis of stenting for carotid web and atherosclerotic disease
CONCLUSION: Stenting for CaW was found to be technically simpler than CAD and not to confer increased risk of baroreceptor dysregulation. Intimal hyperplasia was uncommon in CaW cases.PMID:37563917 | DOI:10.1177/15910199231188856 (Source: Atherosclerosis)
Source: Atherosclerosis - August 11, 2023 Category: Cardiology Authors: Ehizele M Osehobo Raul G Nogueira Nilushi Karunamuni Sitara Koneru Achanti David Landzberg Qasem Al Shaer Jonathan A Grossberg Alhamza Al-Bayati Diogo C Haussen Source Type: research

Comparative analysis of stenting for carotid web and atherosclerotic disease
CONCLUSION: Stenting for CaW was found to be technically simpler than CAD and not to confer increased risk of baroreceptor dysregulation. Intimal hyperplasia was uncommon in CaW cases.PMID:37563917 | DOI:10.1177/15910199231188856 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - August 11, 2023 Category: Radiology Authors: Ehizele M Osehobo Raul G Nogueira Nilushi Karunamuni Sitara Koneru Achanti David Landzberg Qasem Al Shaer Jonathan A Grossberg Alhamza Al-Bayati Diogo C Haussen Source Type: research

LB-010 Safety and effectiveness assessment of the surpass evolve (SEASE): a real-world international multicenter study
ConclusionSEASE is the largest international multicenter study reporting outcomes after the implantation of the SE. Our results demonstrate that a 64-wire FD such as the SE has reliable effectiveness and carries a low rate of safety events in the treatment of mainly medium-sized aneurysms.DisclosuresJ. Vivanco-Suarez: None. J. Fifi: None. D. Lopes: None. A. Rodriguez-Calienes: None. A. Devarajan: None. G. Toth: None. T. Patterson: None. D. Altschul: None. G. Cortez: None. R. Hanel: None. E. Liu: None. V. Pereira: None. A. Kühn: None. A. Puri: None. W. Guerrero: None. I. Bach: None. P. Khandelwal: None. S. Satti: No...
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Vivanco-Suarez, J., Fifi, J., Lopes, D., Rodriguez-Calienes, A., Devarajan, A., Toth, G., Patterson, T., Altschul, D., Cortez, G., Hanel, R., Liu, E., Pereira, V., Kühn, A., Puri, A., Guerrero, W., Bach, I., Khandelwal, P., Satti, S., Edhayan, G., Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

Ultrasound- guided balloon angioplasty of occluded artery accompanied by combined disulphonated aluminum phthalocyanine - mediated photodynamic therapy and iodine-125- mediated gamma ray- intravascular brachytherapy
Background and Aims: The balloon angioplasty methods that are currently in use, cause to inflammation and subsequent restenosis. The aim of this study was to evaluate the effect of combined photodynamic therapy and brachytherapy on inflammation and restenosis reduction after balloon angioplasty of the animal occluded common carotid artery model, wherein diagnostic ultrasound is adjuncted with angioplasty and combination therapy system, with a goal of increased safety. (Source: Atherosclerosis)
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: H. Mehrad Source Type: research

Sirolimus-loaded exosomes as a promising vascular delivery system for the prevention of post-angioplasty restenosis
Drug Deliv Transl Res. 2023 Jul 30. doi: 10.1007/s13346-023-01390-z. Online ahead of print.ABSTRACTRestenosis remains the main reason for treatment failure of arterial disease. Sirolimus (SIR) as a potent anti-proliferative agent is believed to prevent the phenomenon. The application of exosomes provides an extended-release delivery platform for SIR intramural administration. Herein, SIR was loaded into fibroblast-derived exosomes isolated by ultracentrifugation. Different parameters affecting drug loading were optimized, and exosome samples were characterized regarding physicochemical, pharmaceutical, and biological prope...
Source: Cell Research - July 30, 2023 Category: Cytology Authors: Fatemeh Mehryab Shahram Rabbani Faezeh Shekari Abdoreza Nazari Nazanin Goshtasbi Azadeh Haeri Source Type: research

O-004 A propensity score-matched comparative study of balloon guide catheters vs conventional guide catheters for mechanical thrombectomy with stenting in tandem strokes: comparison of 1st-pass effect, symptomatic ICH, and 90-day functional outcomes
ConclusionBGCs used for concurrent MT-carotid revascularization with flow arrest were safe and resulted in superior clinical and angiographic outcomes in tandem stroke patients.Abstract O-004 Table 1Multivariate logistic regression analysis performed after propensity score matching to compare procedural parameters and angiographic and clinical outcomes between balloon guide catheter and conventional guide catheter groupsDisclosures A. Baig: None. M. Waqas: None. R. Turner: None. C. Kuo: None. B. Donnelly: None. P. Lai: None. K. Raygor: None. M. Bouslama: None. J. Lim: None. J. Neumaier: None. J. Cappuzzo: None. J. Davies: ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Baig, A., Waqas, M., Turner, R., Kuo, C., Donnelly, B., Lai, P., Raygor, K., Bouslama, M., Lim, J., Neumaier, J., Cappuzzo, J., Davies, J., Snyder, K., Siddiqui, A., Levy, E. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-044 The safety and feasibility of a care-hotel model in elective neuroendovascular interventions - a single institutional experience
ConclusionsThis preliminary fast-track model is safe, feasible, and cost-effective for carefully selected patients undergoing elective neuroendovascular interventions. Careful patient selection combined with discharge readiness criteria is essential to minimize readmissions.Disclosures A. Ghaith: None. W. Freeman: None. S. Kashyap: None. R. Chadha: None. E. Greco: None. E. Bojaxhi: None. C. Perez- Vega: None. W. Fox: None. R. Tawk: None. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ghaith, A., Freeman, W., Kashyap, S., Chadha, R., Greco, E., Bojaxhi, E., Perez- Vega, C., Fox, W., Tawk, R. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-017 Optical coherence tomography - intravascular imaging for carotid artery stenosis and stenting
ConclusionOCT may be a valuable adjunct tool during carotid artery stenting, especially for plaque characterization in non-stenotic carotid artery disease. OCT catheters can be easily delivered, even in tortuous anatomy. Operators may feel more confident in their management decisions and choice of devices.Disclosures A. Kuhn: None. J. Singh: None. S. Sarid: None. M. Garcia: None. A. Puri: 1; C; NIH, Microvention, Cerenovus, Medtronic Neurovascular and Stryker Neurovascular. 2; C; Medtronic Neurovascular, Stryker NeurovascularBalt, Q’Apel Medical, Cerenovus, Microvention, Imperative Care, Agile, Merit, CereVasc and Ar...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Sarid, S., Garcia, M., Puri, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-033 Optimization of endovascular treatment for patients with acute carotid plaque rupture and free- floating thrombus by use of two overlapping closed-cell stents with different radial force
ConclusionUse of the Carotid Wallstent as the first stent to secure the free-floating thrombus allows save delivery of the Xact stent which then adds a second closed-cell mesh layer as well as the needed radial force to expand the stent construct. This approach may decrease if not eliminate the need for post-stent angioplasty in the acute setting thus decreasing risk of thromboembolic complication.Disclosures A. Kuhn: None. J. Singh: None. S. Sarid: None. M. Garcia: None. A. Puri: 1; C; NIH, Microvention, Cerenovus, Medtronic Neurovascular and Stryker Neurovascular. 2; C; Medtronic Neurovascular, Stryker NeurovascularBalt,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Sarid, S., Garcia, M., Puri, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-095 Serial dilation technique for ulnar artery access in neuro-endovascular procedures: technical report and systematic review of the literature
ConclusionWe report our technique of serial dilation of the ulnar artery for neuroendovascular procedures and provide a systematic review of the literature for complication avoidance in ulnar artery access.Abstract E-095 Table 1Literature review of ulnar artery access for endovascular neuro-intervention Study Mean Age (Years) # Patients Reason for Ulnar Access Procedure (n) Mean Artery Size (mm) Total Arteries Catheterized (n) Complications (n) Dossani RH, et al. 2021 70.3 7 Small RA Dx Angiogram (4)MMA embolization (3)CA Stenting (1)Thrombectomy for in-stent thrombosis(1) 2.57 17 Ulnar occlusion on 30 day follow-...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., Wali, A., McCann, C., Tucker, B., Olson, S., Steinberg, J., Santiago-Dieppa, D., Khalessi, A., Pannell, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-109 Use of intravascular lithotripsy prior to stenting of severely calcified carotid artery stenoses
ConclusionIVL is a novel technique that simplifies endovascular carotid stenting procedures in previously known challenging conditions. This technique minimizes the risk of complications and optimizes patient outcomes with promising early imaging follow-up. Severely calcified and/or circumferential carotid artery lesions with plaques protruding into the vessel lumen may be more easily amenable for endovascular treatment in the future.Abstract E-109 Figure 1Disclosures A. Kuhn: None. J. Singh: None. S. Sarid: None. M. Garcia: None. A. Puri: 1; C; NIH, Microvention, Cerenovus, Medtronic Neurovascular and Stryker Neurovascula...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Sarid, S., Garcia, M., Puri, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-230 The widespread incorporation of IVUS into neuroendovascular interventions
ConclusionThis literature review and summarization of the clinical utility of IVUS aims to educate providers on the variety of applications of IVUS as a valuable adjunct in patient care in addition to the supporting evidence behind each application, including comparison to other imaging modalities. In conclusion, IVUS remains a powerful tool in endovascular interventions for both cerebral venous disease and carotid artery interventions. The hope is to one day develop a formal future consensus for the standardized practice parameters for all of the previously listed utilizations, especially due to the low-risk profile and m...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Richardson, A., Richardson, O. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-270 Correlation of CT angiography to digital substraction angiography in carotid stenosis with real-world assessment of overestimation of CS on CTA
ConclusionOf patients with stenosis found on CTA, over 88% also had stenosis on DSA, with this PPV in line with previous studies. The percent-stenosis value from CTA and DSA was weakly correlated, likely due to measurement technicalities, but does not affect clinical judgement of stenosis overall. Severe calcification found on CTA may potentially indicate non-stenosis on DSA.Disclosures R. Abbas: None. W. Chong: None. Y. Hai: None. K. El Naamani: None. M. Gooch: 2; C; Medtronic. S. Tjoumakaris: 2; C; microvention. A. Flanders: None. P. Jabbour: 2; C; Medtronic. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Abbas, R., Chong, W., Hai, Y., El Naamani, K., Gooch, M., Tjoumakaris, S., Flanders, A., Jabbour, P. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research