Accuracy of Computed Tomography Angiography for Diagnosing Extracranial Mural Lesions in Patients with Acute Internal Carotid Artery Occlusion: Correlation with Digital Subtraction Angiography
Conclusions: CTA accurately differentiates extracranial CML from thromboembolic etiology in acute ICA occlusion. The pattern of the occlusion and the artery widening help to establish the location and the etiology of the occlusion.PMID:37511782 | PMC:PMC10381416 | DOI:10.3390/jpm13071169 (Source: Atherosclerosis)
Source: Atherosclerosis - July 29, 2023 Category: Cardiology Authors: Miriam Fern ández-Gómez F élix Gallo-Pineda Carlos Hidalgo-Barranco Gracia Castro-Luna Patricia Mart ínez-Sánchez Source Type: research

Epigenetic regulation of vascular smooth muscle cell phenotypic switch and neointimal formation by PRMT5
CONCLUSIONS: Our results identify PRMT5 as a novel regulator in VSMC phenotypic switch and suggest that inhibition of PRMT5 may represent an effective therapeutic strategy for proliferative vascular diseases.PMID:37486354 | DOI:10.1093/cvr/cvad110 (Source: Cell Research)
Source: Cell Research - July 24, 2023 Category: Cytology Authors: Ni Zhu Zhi-Fu Guo Kyosuke Kazama Bing Yi Nopprarat Tongmuang Huijun Yao Ruifeng Yang Chen Zhang Yongwen Qin Lin Han Jianxin Sun Source Type: research

Epigenetic regulation of vascular smooth muscle cell phenotypic switch and neointimal formation by PRMT5
CONCLUSIONS: Our results identify PRMT5 as a novel regulator in VSMC phenotypic switch and suggest that inhibition of PRMT5 may represent an effective therapeutic strategy for proliferative vascular diseases.PMID:37486354 | DOI:10.1093/cvr/cvad110 (Source: Atherosclerosis)
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: Ni Zhu Zhi-Fu Guo Kyosuke Kazama Bing Yi Nopprarat Tongmuang Huijun Yao Ruifeng Yang Chen Zhang Yongwen Qin Lin Han Jianxin Sun Source Type: research

Epigenetic regulation of vascular smooth muscle cell phenotypic switch and neointimal formation by PRMT5
CONCLUSIONS: Our results identify PRMT5 as a novel regulator in VSMC phenotypic switch and suggest that inhibition of PRMT5 may represent an effective therapeutic strategy for proliferative vascular diseases.PMID:37486354 | DOI:10.1093/cvr/cvad110 (Source: Atherosclerosis)
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: Ni Zhu Zhi-Fu Guo Kyosuke Kazama Bing Yi Nopprarat Tongmuang Huijun Yao Ruifeng Yang Chen Zhang Yongwen Qin Lin Han Jianxin Sun Source Type: research

Imaging diagnosis of intracranial atherosclerosis stenosis-related large vessel occlusion before and during endovascular therapy
We describe the diagnosis of intracranial atherosclerotic stenosis-related large vessel occlusion from the perspectives of "thrombus imaging," "perfusion," and "occlusion margin."PMID:37416315 | PMC:PMC10320000 | DOI:10.3389/fneur.2023.1168004 (Source: Atherosclerosis)
Source: Atherosclerosis - July 7, 2023 Category: Cardiology Authors: Takeshi Yoshimoto Source Type: research

Imaging diagnosis of intracranial atherosclerosis stenosis-related large vessel occlusion before and during endovascular therapy
We describe the diagnosis of intracranial atherosclerotic stenosis-related large vessel occlusion from the perspectives of "thrombus imaging," "perfusion," and "occlusion margin."PMID:37416315 | PMC:PMC10320000 | DOI:10.3389/fneur.2023.1168004 (Source: Atherosclerosis)
Source: Atherosclerosis - July 7, 2023 Category: Cardiology Authors: Takeshi Yoshimoto Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
CONCLUSIONS: These studies show that an N-cadherin-binding and fibronectin-binding chimeric peptide is effective in inhibiting SMC migration in vitro and in vivo and limiting neointimal hyperplasia after balloon angioplasty without affecting EC repair. These results establish the potential of an advantageous SMC-selective strategy for antirestenosis therapy.PMID:37409527 | DOI:10.1161/ATVBAHA.123.319400 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 6, 2023 Category: Cardiology Authors: Jonah Burke-Kleinman Jonathan Rubianto Guangpei Hou J Paul Santerre Michelle P Bendeck Source Type: research

Ultrasound examination of the carotid artery for improved prediction of cardiovascular events and the effect of statin treatment in advanced atherosclerosis : An observational study
CONCLUSION: The prediction of cardiovascular events was better with plaque burden measurements than with the PROCAM score. Treatment with statins in subjects with advanced carotid atherosclerosis (types III-IV b findings on ultrasound) significantly improved the prognosis in a nonrandomized observational study.PMID:37402837 | DOI:10.1007/s00059-023-05197-z (Source: Atherosclerosis)
Source: Atherosclerosis - July 4, 2023 Category: Cardiology Authors: Ansgar Adams Waldemar Bojara Michel Romanens Source Type: research

Ultrasound examination of the carotid artery for improved prediction of cardiovascular events and the effect of statin treatment in advanced atherosclerosis : An observational study
CONCLUSION: The prediction of cardiovascular events was better with plaque burden measurements than with the PROCAM score. Treatment with statins in subjects with advanced carotid atherosclerosis (types III-IV b findings on ultrasound) significantly improved the prognosis in a nonrandomized observational study.PMID:37402837 | DOI:10.1007/s00059-023-05197-z (Source: Herz)
Source: Herz - July 4, 2023 Category: Cardiology Authors: Ansgar Adams Waldemar Bojara Michel Romanens Source Type: research

Ultrasound examination of the carotid artery for improved prediction of cardiovascular events and the effect of statin treatment in advanced atherosclerosis : An observational study
CONCLUSION: The prediction of cardiovascular events was better with plaque burden measurements than with the PROCAM score. Treatment with statins in subjects with advanced carotid atherosclerosis (types III-IV b findings on ultrasound) significantly improved the prognosis in a nonrandomized observational study.PMID:37402837 | DOI:10.1007/s00059-023-05197-z (Source: Atherosclerosis)
Source: Atherosclerosis - July 4, 2023 Category: Cardiology Authors: Ansgar Adams Waldemar Bojara Michel Romanens Source Type: research