Epigenetic regulation of vascular smooth muscle cell phenotypic switch and neointimal formation by PRMT5

CONCLUSIONS: Our results identify PRMT5 as a novel regulator in VSMC phenotypic switch and suggest that inhibition of PRMT5 may represent an effective therapeutic strategy for proliferative vascular diseases.PMID:37486354 | DOI:10.1093/cvr/cvad110

Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: Ni Zhu Zhi-Fu Guo Kyosuke Kazama Bing Yi Nopprarat Tongmuang Huijun Yao Ruifeng Yang Chen Zhang Yongwen Qin Lin Han Jianxin Sun Source Type: research