Ultrasound-Guided Periadventitial Administration of Rapamycin-Fibrin Glue Attenuates Neointimal Hyperplasia in the Rat Carotid Artery Injury Model

CONCLUSION: Periadventitial delivery of RPM-FG contributed to inhibiting IH in the rat carotid artery injury model without compromising re-endothelialization. Additionally, FG provided a promising platform for the future development of a safe, effective, and minimally invasive perivascular drug delivery method to treat vascular disease.PMID:37852309 | DOI:10.1016/j.ejps.2023.106610

Source: European Journal of Pharmaceutical Sciences - October 18, 2023 Category: Drugs & Pharmacology Authors: Zhentao Qiao Fuhang Wang Dongjian Han Yuansong Zhuang Qingjiao Jiang Yi Zhang Miaomiao Liu Quanxu An Zhiwei Wang Deliang Shen Source Type: research