Carcinoma of Unknown Primary Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Positive factors on survival of head and neck cancer of unknown primary: what the clinician can do
CONCLUSION AND SIGNIFICANCE: Aspects for clinical decision-making: Curative MST and SCC histology were the most significant predictors for improved OS. Categorizing LN into 1, 2-3, and >3 LNs was more significant than the traditional N classification. The addition of CT to curative MST has a stronger impact on survival than HPV and N classifications.PMID:37842931 | DOI:10.1080/00016489.2023.2265937 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - October 16, 2023 Category: ENT & OMF Authors: Firas Khalil Michael Koch Heinrich Iro Matti Sievert Marlen Haderlein Sabine Semrau Rainer Fietkau Abbas Agaimy Claudia Scherl Source Type: research

Management of Unknown Primary Head and Neck Cancer with Radiation Therapy in the Era of Human Papillomavirus (HPV): No Longer Cutting Down the Tree to Get an Apple
CONCLUSIONS: Prospective evidence is lacking, and the available studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in work-up, treatment, inclusion criteria, and follow-up. Regardless, advances in science and technology have ushered in more precise approaches with a high degree of customization, particularly given the increased proportion of patients presenting with human papillomavirus-related disease.PMID:37844736 | DOI:10.1016/j.radonc.2023.109952 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2023 Category: Radiology Authors: Allen M Chen Source Type: research

Management of unknown primary head and neck cancer with radiation therapy in the era of human papillomavirus (HPV): No longer cutting down the tree to get an apple
CONCLUSIONS: Prospective evidence is lacking, and the available studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in work-up, treatment, inclusion criteria, and follow-up. Regardless, advances in science and technology have ushered in more precise approaches with a high degree of customization, particularly given the increased proportion of patients presenting with human papillomavirus-related disease.PMID:37844736 | DOI:10.1016/j.radonc.2023.109952 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2023 Category: Radiology Authors: Allen M Chen Source Type: research

Management of Unknown Primary Head and Neck Cancer with Radiation Therapy in the Era of Human Papillomavirus (HPV): No Longer Cutting Down the Tree to Get an Apple
In 2002, Nieder et al published a classic review using the metaphorical phrase of “cutting down the tree to get an apple” to describe the radiotherapeutic management of squamous cell carcinoma metastatic to the cervical lymph nodes of unknown primary origin [1]. This analogy, which was meant to illustrate the unnecessary and wasteful destruction of all that was good, in the p rocess of achieving a narrow aim, is worthy of consideration in light of advancements in biology and technology which have improved the level of precision in which this disease has been approached over the last 20 years. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - October 14, 2023 Category: Radiology Authors: Allen M. Chen Tags: Review Article Source Type: research

2-Year survival benefit from immunotherapy for squamous cell cancer with cancer of unknown primary in mediastinum: a case report
In conclusion, immunotherapy targeting PD-1/PD-L1 in combination with chemotherapy may play a crucial role in the later-line treatment and palliative care of CUP. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - October 11, 2023 Category: Cancer & Oncology Source Type: research

Dose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting
CONCLUSION: Omitting contralateral nCTV irradiation and mCTV irradiation will significantly reduce toxicity. The accumulated high dose volumes can be minimised using protons for re-irradiation. However, the use of protons for primary treatment provides limited benefit in most patients.PMID:37815913 | DOI:10.1080/0284186X.2023.2263156 (Source: Acta Oncologica)
Source: Acta Oncologica - October 10, 2023 Category: Cancer & Oncology Authors: Anne Ivalu Sander Holm Ulrik Vindelev Elstr øm Signe Bergliot Nielsen Kenneth Jensen Source Type: research

Cancers, Vol. 15, Pages 4614: Primary Retroperitoneal Carcinomas: New Insights into Pathogenesis and Clinical Management in Comparison with Ovarian Carcinomas and Carcinoma of Unknown Primary
a Primary retroperitoneal carcinomas are very rare tumors. Their pathogenesis remains unknown but may be associated with that of ovarian carcinomas, considering the similarity in morphology and gender preference. Although metaplasia of coelomic epithelium is the most widely accepted theory, the pathogenesis of retroperitoneal carcinomas may differ by histologic subtype, like ovarian carcinomas. Mucinous carcinoma, which develops in both women and men, may originate in both primordial germ cells and Walthard cell nests that may be derived from the fallopian tube. Serous carcinomas may be associated with endosalpingiosis...
Source: Cancers - September 18, 2023 Category: Cancer & Oncology Authors: Isao Otsuka Tags: Review Source Type: research

Rapid progressive spontaneous hemothorax caused by carcinoma of unknown primary: A very rare case
We present a case of spontaneous hemothorax which was caused by carcinoma of unknown primary. Since it was very rare cause of hemothorax, we had difficulty in deciding the course of treatment. AbstractWe present a very rare case of spontaneous hemothorax which was caused by carcinoma of unknown primary. To the best of our knowledge, there are no other such cases reported worldwide. The patient was 72-year-old male who was referred to our department for massive hemothorax. We undertook surgical treatment for haemostasis, and found multiple tumours which led to the diagnosis of carcinoma of unknown primary as the cause of ha...
Source: Respirology Case Reports - September 13, 2023 Category: Respiratory Medicine Authors: Sachie Koike, Nobutaka Kobayashi, Masahisa Miyazawa, Naho Yamashita Tags: CASE REPORT Source Type: research