Clinical and radiological characteristics of patients with collapse or fistula of the saccule as evaluated by inner ear MRI.
Conclusions and significance: NVS seems to be multifactorial and could be linked to hydropic ear disease, third-mobile window pathologies and congenital malformation. PMID: 31961235 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 21, 2020 Category: ENT & OMF Authors: Eliezer M, Poillon G, Lévy D, Guichard JP, Toupet M, Houdart E, Attyé A, Hautefort C Tags: Acta Otolaryngol Source Type: research

The outcomes of endoscopic myringoplasty: packing with gelatin sponge versus packing with nothing.
Abstract Background: Packing with gelatin sponge has long been widely used in myringoplasty. However, there is no research on packing with nothing.Aims/objectives: To analyse the differences between packing with gelatin sponge and packing with nothing.Material and methods: Patients with tympanic membrane perforation were randomly divided into a packing with gelatin sponge group and a packing with nothing group. Differences between the groups were compared.Results: The operation time of group A (34.00 ± 1.05 min) was significantly shorter than that of group B (42.20 ±&thins...
Source: Acta Oto-Laryngologica - January 21, 2020 Category: ENT & OMF Authors: Wang D, Ren T, Wang W Tags: Acta Otolaryngol Source Type: research

Early detection of hearing impairment in type 2 diabetic patients.
Conclusions and significance: There can be cochlear dysfunction and high frequency hearing loss in diabetic patients with normal hearing thresholds of conventional frequencies. The examinations of HFA and DPOAEs are of great importance for early diagnosis of hearing loss in type 2 diabetic patients. PMID: 31961256 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 21, 2020 Category: ENT & OMF Authors: Li Y, Liu B, Li J, Xin L, Zhou Q Tags: Acta Otolaryngol Source Type: research

Efficacy of balloon Eustachian tuboplasty on the quality of life in children with Eustachian tube dysfunction.
Conclusion and significance: Our results demonstrate that BET may be a safe, first-line intervention that positively effects the quality of life in children with chronic ETD. PMID: 31961259 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 21, 2020 Category: ENT & OMF Authors: Demir B, Batman C Tags: Acta Otolaryngol Source Type: research

Programmed death ligand-1 expression is associated with stage and histological grade of parotid carcinoma.
Conclusions: PD-L1 expression was positive in approximately 50% of high- grade carcinomas, which was similar to the level in head and neck squamous cell carcinoma. In patients with other cancers, it has been reported that an anti-PD-1 monoclonal antibody was more effective against tumors with higher PD-L1 expression. Therefore, it could be a possible new therapeutic option for patients with highly malignant parotid tumors that have a poor prognosis. PMID: 31944154 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 16, 2020 Category: ENT & OMF Authors: Higashino M, Kawata R, Nishikawa S, Terada T, Haginomori SI, Kurisu Y, Hirose Y Tags: Acta Otolaryngol Source Type: research

Transcervical endoscopic approach for parapharyngeal space: a cadaver study and clinical practice.
Conclusions and significance: The transcervical endoscopic approach provides a wide corridor for surgery in the parapharyngeal space. With accurate hemostasis, this approach can be applied as the first-line strategy for parapharyngeal surgeries in selected patients. PMID: 31933416 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 14, 2020 Category: ENT & OMF Authors: Fang Y, Wu H, Tan AD, Cheng L Tags: Acta Otolaryngol Source Type: research

Is there an association between the parameters of arterial stifness and tinnitus?
kcay M, Terzi O Abstract Background: Increasing arterial stiffness is associated with atherosclerosis and there is an association between atherosclerosis and tinnitus may occur.Objectives: The aim of this study was to investigate the relationship between arterial stiffness and tinnitus using the central pulse-wave analysis method.Methods: This prospective, single center study included 98 participants, comprising 49 patients diagnosed with subjective idiopathic tinnitus (Group 1) and a control group of 49 healthy subjects (Group 2). The Mobil-O-Graph 24 h Pulse wave analysis (PWA) Monitor (I.E.M. GmbH, Stolb...
Source: Acta Oto-Laryngologica - January 13, 2020 Category: ENT & OMF Authors: Gedikli Ö, Kemal O, Yıldırım U, Çeçen AB, Karabulut H, Akcay M, Terzi O Tags: Acta Otolaryngol Source Type: research

The relationships among mastoid air cell development, tympanic sinus depth, and residual disease after surgery in children with congenital cholesteatoma.
Conclusions and significance: After surgery for congenital cholesteatoma, residual disease is more likely to occur in patients with marked mastoid growth, possibly because they have deep tympanic sinuses. Cases in which congenital cholesteatoma spreads to the mastoid air cells are classified as stage IV in Potsic's system, but our findings indicate that invasion into a deep tympanic sinus is more important than invasion into the mastoid air cells. PMID: 31928292 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 13, 2020 Category: ENT & OMF Authors: Takahashi M, Yamamoto Y, Koizumi H, Motegi M, Komori M, Yamamoto K, Yaguchi Y, Kojima H Tags: Acta Otolaryngol Source Type: research

Substantial intrinsic variability in chemoradiosensitivity of newly established anaplastic thyroid cancer cell-lines.
Conclusions and significance: We describe a series of new ATC cell lines demonstrating large heterogeneity in the response to cytostatic drugs and the BRAF inhibitor vemurafenib. The observations are relevant to future attempts to optimize treatment combinations for ATC. PMID: 31922436 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 10, 2020 Category: ENT & OMF Authors: Gretarsson S, Nygren A, Rosendahl AH, Mylona N, Kjellén E, Jin Y, Paulsson K, Borg Å, Brun E, Tennvall J, Bergenfelz A, Greiff L, Wennerberg J, Ekblad L Tags: Acta Otolaryngol Source Type: research

Change of VOR gain and pure-tone threshold after single low-dose intratympanic gentamicin injection in Meniere's disease.
Conclusion and significance: Our results suggest that ITG appears to cause a differential loss of function across three semicircular canals. Furthermore, if VOR gain difference of horizontal canal is relatively low after initial ITG, patient might have poor vertigo control and be required another ITG. PMID: 31909683 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - January 7, 2020 Category: ENT & OMF Authors: Lee JY, Kim MB Tags: Acta Otolaryngol Source Type: research

Evaluation of bone mineral density and 25-(OH) vitamin D levels in middle-aged and elderly women with recurrent benign paroxysmal positional vertigo.
This study aimed to investigate the correlation between bone mineral density (BMD), 25-(OH) vitamin D, and serum calcium levels in patients with benign paroxysmal positional vertigo (BPPV) in middle-aged and elderly women.Material and methods: A total of 103 women with two or more recurrent BPPV episodes (group A) and 80 age-matched healthy controls (group B) were recruited. All subjects had BMD and serum 25-(OH) D levels measurements taken, and the results were compared.Results: BMD was reduced in group A, and the proportion of osteoporosis was higher than in group B (p = .039). The BMD T-score and 25-(OH) v...
Source: Acta Oto-Laryngologica - December 26, 2019 Category: ENT & OMF Authors: Wang Z, Yao G, Tao X, Zhang J, Zhang T, Wu Z Tags: Acta Otolaryngol Source Type: research

Clinical characteristics of petrosal cholesteatoma and value of MRI-DWI in the diagnosis.
Conclusions: The clinical manifestations of petrosal cholesteatoma are various, and sometimes it is difficult to differentiate it from other petrosal lesions. The combining with MRI-DWI and CT examination is necessary and has an advantage. PMID: 31876216 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 26, 2019 Category: ENT & OMF Authors: Zuo W, Wang F, Yang S, Han D, Dai P, Shen W, Hou Z, Han W Tags: Acta Otolaryngol Source Type: research

Adverse effects of semicircular circle angles variation on Epley repositioning procedure: a study on reconstruction of Micro-CT images 3D.
Conclusion: 1. Variation could be found in angles between the semicircular canals and the standard planes of skulls, which meant variation of semicircular canals' location existing in skulls. 2. The variation of angles between PSC and sagittal plane could have an adverse effect on the Epley maneuver when the angle was less than 45°, which may cause the Epley maneuver to be invalid. PMID: 31876219 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 26, 2019 Category: ENT & OMF Authors: Tang X, Tang J, Gong L, Ke R, Tan S, Tang A Tags: Acta Otolaryngol Source Type: research

Neutrophil-lymphocyte ratio as a valuable prognostic marker in idiopathic sudden sensorineural hearing loss.
This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).Material and methods: This retrospective, case-control clinical trial analyzed data from 186 subjects diagnosed with ISSNHL and admitted to Kyung-Hee Medical Center between March 2016 and February 2019. Hematologic and audiometric parameters were measured.Results: NLR showed a linear correlation with hearing recovery in patients with ISSNHL, with hearing gain (dB) = 56.698 - 3.718 × NLR (r2 = 0.451, p = .001). He...
Source: Acta Oto-Laryngologica - December 26, 2019 Category: ENT & OMF Authors: Kang JW, Kim MG, Kim SS, Im HI, Dong SH, Kim SH, Yeo SG Tags: Acta Otolaryngol Source Type: research

Vestibular evoked myogenic potential (VEMP) results in migraine and migrainous vertigo.
Conclusions: The increased rate of absent VEMPs was associated with the hypoperfusion of the sacculo-collic reflex pathway in migraine patients. In addition, it was concluded that VEMP reflex responses appear to be insufficient to differentiate between VM and migraine diagnoses. PMID: 31859539 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 20, 2019 Category: ENT & OMF Authors: Özdemir D, Akpınar ÇK, Küçüköner Ö, Mehel DM, Bedir A, Akgül G, Can E, Özgür A Tags: Acta Otolaryngol Source Type: research

Use of intraoperative CT scanning for quality control assessment of cochlear implant electrode array placement.
Conclusion and significance: The current standard of care for CI is to insert EAs without feedback as to final location. iCT provides surgeons with rapid post-insertion feedback which allows detection and correction of suboptimally placed EAs as well as refinement of surgical technique. PMID: 31859576 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 20, 2019 Category: ENT & OMF Authors: Labadie RF, Schefano AD, Holder JT, Dwyer RT, Rivas A, O'Malley MR, Noble JH, Dawant BM Tags: Acta Otolaryngol Source Type: research

Repair effect of xenogeneic acellular dermal matrix during external auditory canal reconstruction after canal wall down mastoidectomy.
Conclusions and Significance: Xeno-ADM could be a safe, effective and simple method for repairing skin defect in the reconstruction of EAC after CWD mastoidectomy. PMID: 31859578 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 20, 2019 Category: ENT & OMF Authors: Zang J, Yang B, Feng S, Jiang X Tags: Acta Otolaryngol Source Type: research

Long-term evolution of the electrical stimulation for cochlear implant adult patients. The role of a progressive adaptation method.
Abstract Background: In clinical experience patients who do not frequently check the cochlear implant (CI) maps have poor auditory performance and poor acceptance of map variations over time.Aims: The aim of the present study was to evaluate the effect of CI map optimization on both speech perception and subjective hearing in a group of CI patients with a long-standing map.Material and methods: 14 patients (6 females and 8 males; age range 16-77, mean age 45.86 ± 23.85 years) fitted with a unilateral CI (Cochlear Ltd, Sydney, Australia) and a map unchanged for at least 12 months were ev...
Source: Acta Oto-Laryngologica - December 19, 2019 Category: ENT & OMF Authors: Zinfollino M, Cariddi C, Ardito A, Casulli M, Malerba P, Quaranta N Tags: Acta Otolaryngol Source Type: research

Influenza A virus infection induces indoleamine 2,3-dioxygenase (IDO) expression and modulates subsequent inflammatory mediators in nasal epithelial cells.
Conclusions and significance: Viral infection results in depletion of tryptophan and accumulation of kynurenine via increased cellular IDO activity. Inhibition of IDO activity or replenishment of tryptophan by local application may be a good therapeutic strategy for limiting the initial damage caused by influenza virus in nasal epithelial cells. PMID: 31852346 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 18, 2019 Category: ENT & OMF Authors: Lin YT, Lin CF, Yeh TH Tags: Acta Otolaryngol Source Type: research

A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland.
nvall L Abstract Background and aims: Stage II cancer of the tongue is mostly managed surgically both locally and regionally. However, indications for postoperative radiotherapy and reconstructive options vary between centers. This paper aims to describe differences in treatment in a geographically homogenous cohort.Methods: A retrospective comparison was made between two cohorts of clinical T2N0 tongue cancer from Finland and Sweden. The Finnish cohort included 75 patients and the Swedish 54. All patients had curative intent of treatment and no previous head and neck cancer. Data analyzed consisted of pathologica...
Source: Acta Oto-Laryngologica - December 18, 2019 Category: ENT & OMF Authors: Mäkitie A, Kamali A, Mroueh R, Lindford A, Koivunen P, Autio T, Lassus P, Halle M, Bäck L, Palmgren B, Hammarstedt-Nordenvall L Tags: Acta Otolaryngol Source Type: research

Clinical outcome and comparison between squamous and non-squamous cell carcinoma of the larynx.
Conclusions and significance: Primary nSCC of the larynx is rare, and its diagnosis depends on comprehensive immunohistochemical examination, as the clinical characteristics are non-specific compared with SCC. The overall prognosis of nSCC is relatively poor compared with that of SCC in the larynx. PMID: 31852360 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 18, 2019 Category: ENT & OMF Authors: Chen L, Deng W, Li C, Lau H, Tao L, Wang S, Zhou L, Zhang M Tags: Acta Otolaryngol Source Type: research

Transoral robotic surgery: a 4-year learning experience in a single Danish Cancer Centre.
Conclusions and significance: Lower complication rates may be explained by improved surgical experience, through better patient selection and changes in indications for TORS. Future applications of TORS will be in the management of CUP and as part of a Danish national randomized clinical trial aiming to compare long-term functional outcomes after treatment of early-stage OPSCC with TORS versus radiation treatment. PMID: 31849248 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 18, 2019 Category: ENT & OMF Authors: Isenberg AL, Channir HI, von Buchwald C, Rubek N, Friborg J, Kiss K, Charabi BW Tags: Acta Otolaryngol Source Type: research

Clinical features of patients with high and normal CSFP in venous pulsating tinnitus.
Abstract Background: Few doctors associate high cerebrospinal fluid pressure (CSFP) with vascular tinnitus. On the basis of predecessors, we found there were some differences in clinical data between patients with elevated versus normal CSFP.Aims/objectives: To explore the differences in clinical data between the elevated CSFP group and the normal CSFP group.Materials and methods: A total of 27 patients with venous pulsating tinnitus who underwent measurement of CSFP through IP were reviewed. Clinical data were compared between the two groups.Result: Twelve patients (44.44%) had high CSFP ranging from 210-245 mm H...
Source: Acta Oto-Laryngologica - December 18, 2019 Category: ENT & OMF Authors: Wang D, Wang W Tags: Acta Otolaryngol Source Type: research

The use of the MUSS and the SIR scale in late-implanted prelingually deafened adolescents and adults as a subjective evaluation.
Conclusions and significance: The MUSS and the SIR scale could be used to evaluate the oral ability of late implanted patients. The SIR scale could be used to perform a rapid assessment and the MUSS could help provide more information. The combination of the two scales could be used to evaluate vocal ability more accurately and effectively. PMID: 31825697 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Liu R, Jiao Q, Ji F, Wang Q, Zhao H, Li J, Yang S Tags: Acta Otolaryngol Source Type: research

Post-operative complications due to salvage total laryngectomy for recurrent laryngeal cancer after radiotherapy - a multicentre retrospective study.
Conclusions and significance: We demonstrated that PIG applying PMMCF significantly reduced the PCF rate due to STL. In the future, surgeons need to conduct research focused on additional innovations to reduce post-operative complications as much as possible. PMID: 31825701 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Okamoto I, Matsuki T, Sato H, Kondo T, Fushimi C, Okada T, Miura K, Yamashita T, Omura G, Tsukahara K Tags: Acta Otolaryngol Source Type: research

Influence of maximum power output on speech understanding with bone anchored hearing systems.
Abstract Background: Maximum power output (MPO) levels of bone anchored hearing systems (BAHS) vary between different devices, but are significantly lower than those of conventional hearing aids, potentially limiting speech understanding.Aims/objectives: To investigate, how MPO influences speech understanding in quiet and in noise in BAHS users.Materials and methods: 12 adult BAHS users with a bilateral conductive hearing loss and additional sensorineural hearing components between 4 and 45 dB (500-4000 Hz) participated in the study. Speech understanding was measured at 65 dB in quiet and in n...
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Gawliczek T, Wimmer W, Caversaccio M, Kompis M Tags: Acta Otolaryngol Source Type: research

Clinical features of sarcoidosis patients presenting with head and neck manifestations - a two-center retrospective study and proposal of a diagnostic algorithm for the otorhinolaryngologist.
Conclusions: Sarcoidosis should be considered as a differential diagnosis in patients presenting with head and neck symptoms. The most frequent presenting symptoms were cervical lymphadenopathy and affection of the paranasal sinuses. Therefore, otorhinolaryngologists should be aware of sarcoidosis and help guide referral strategies as they may be the first physicians treating these patients. PMID: 31825705 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Send T, Korsten P, Bertlich M, Braunwarth C, Bootz F, Skowasch D, Jakob M Tags: Acta Otolaryngol Source Type: research

Baseline neutrophil-to-lymphocyte ratio (NLR) is associated with clinical outcome in recurrent or metastatic head and neck cancer patients treated with nivolumab.
This study assessed baseline neutrophil-to-lymphocyte ratio (NLR) as a prognostic and predictive marker for nivolumab efficacy in patients with recurrent/metastatic head and neck cancer (R/M HNC).Material and methods: This retrospective cohort study used medical records of patients with R/M HNC treated with nivolumab from May 2017 to January 2018 at a university hospital in Japan.Results: Twenty-nine patients (median age, 64 years) were included. In univariate analyses, baseline NLR ≥5 was significantly associated with overall survival (HR 4.88; p = .045) and progressive disease (HR 5.0; p =&...
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Ueda T, Chikuie N, Takumida M, Furuie H, Kono T, Taruya T, Hamamoto T, Hattori M, Ishino T, Takeno S Tags: Acta Otolaryngol Source Type: research

Comparison of auditory steady-state response and click-evoked auditory brain response in infants with different types and degrees of hearing loss.
Conclusions and significance: ASSR was one valuable cross-check measure by providing frequency specific information in auditory assessment. PMID: 31825723 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - December 11, 2019 Category: ENT & OMF Authors: Wang X, Cheng Y, Shi J, Sheng X, Wu D, Zhao Y, Li D, He D, Wang H Tags: Acta Otolaryngol Source Type: research

Analysis of related factors of recurrence in horizontal semicircular canal benign paroxysmal positional vertigo: a pilot study.
Conclusions: A weak correlation between RD and abnormal C-test is noted. Presence of RD and abnormal C-test in patients with HSC-BPPV predicts a higher recurrence rate. PMID: 31782327 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 29, 2019 Category: ENT & OMF Authors: Ding L, Lin T, Zhou X, Han J, Xu A Tags: Acta Otolaryngol Source Type: research

Vestibular-evoked myogenic potentials in patients with large vestibular aqueduct syndrome.
Conclusions and significance: We discovered a severer otolithic dysfunction in adults than in children patients. We recommend cVEMP a more effective and sensitive method than oVEMP in assessment of LAVS adult patients. PMID: 31769324 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 26, 2019 Category: ENT & OMF Authors: Zhang Y, Chen Z, Zhang Y, Hu J, Wang J, Xu M, Zhang Q Tags: Acta Otolaryngol Source Type: research

Regularity of voice recovery and arytenoid motion after closed reduction in patients with arytenoid dislocation: a self-controlled clinical study.
Conclusions and significance: Closed reduction for patients with arytenoid dislocation is an effective procedure. A time window between 4.08th and 5.22th day (at a confidence level of 95%) after the last closed reduction was identified to be critical for voice recovery. PMID: 31762355 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 25, 2019 Category: ENT & OMF Authors: Zheng T, Lou Z, Li X, Teng Y, Li Y, Lin X, Lin Z Tags: Acta Otolaryngol Source Type: research

Electrically evoked ABR during cochlear implantation and postoperative development of speech and hearing abilities in infants with common cavity deformity as a type of inner ear malformation.
Conclusion and Significance: The brainstem auditory pathways of the infants were considered intact on the basis of the eV peak latencies in the eABRs. The postoperative development of their speech and hearing abilities and their educational settings varied, probably because of the twofold higher thresholds of their eABRs and limited number of auditory neural units. PMID: 31762359 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 25, 2019 Category: ENT & OMF Authors: Kaga K, Minami S, Enomoto C Tags: Acta Otolaryngol Source Type: research

Receptive language acquisition in a pediatric population with Pendred syndrome and non-syndromic enlarged vestibular aqueduct.
-Thomasen P Abstract Background: Children with Pendred syndrome (PS) and non-syndromic enlarged vestibular aqueduct (NSEVA) represent a group of pre-lingual hearing-impaired individuals with rehabilitation challenges.Objective: To evaluate receptive language capabilities in a pediatric cohort with PS and NSEVA.Materials and methods: Twenty-four (24) children diagnosed with either PS or NSEVA, were examined using the Peabody Picture Vocabulary Test (PPVT) and compared to a cohort of 55 Danish children with normal hearing, as well as to a mixed group of 29 children with hearing impairment of congenital and hereditar...
Source: Acta Oto-Laryngologica - November 23, 2019 Category: ENT & OMF Authors: Mey K, Percy-Smith L, Hallstrøm M, Sandvej M, Cayé-Thomasen P Tags: Acta Otolaryngol Source Type: research

Impact of adjuvant therapy on survival for sinonasal mucosal melanoma.
Conclusions and significance: SNMM had poor prognosis with high rates of local recurrence and metastasis. Adjuvant therapy improved survival outcomes for SNMM. PMID: 31755795 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 22, 2019 Category: ENT & OMF Authors: Lai Y, Meng X, Liu Q, Lu H, Guo L, Wang S, Wang D Tags: Acta Otolaryngol Source Type: research

Impact of posterior septum resection on nasal airflow pattern and warming function.
Abstract Background: The functional significance of the posterior segment of the septum is not fully understood.Aims/Objectives: The purpose of this study was to evaluate the impact of posterior septum resection with varying extents on nasal airflow pattern and warming function, and to determine the appropriate resection extent on posterior septum without disturbing airflow pattern.Material and Methods: Three dimensional models were established from the nasal CT scan of a healthy female volunteer without nasal disease. The models included the normal, as well as 1 cm, 2 cm, and 3 cm extent of p...
Source: Acta Oto-Laryngologica - November 18, 2019 Category: ENT & OMF Authors: Li L, London NR, Zang H, Han D Tags: Acta Otolaryngol Source Type: research

Treatment algorithm for idiopathic sudden sensorineural hearing loss based on epidemiologic surveys of a large Japanese cohort.
Conclusion: An algorithm for the treatment for SSNHL is presented according to the results of epidemiologic surveys in Japan. It is expected that this algorithm can provide a guide to choosing the suitable treatment for SSNHL patients. PMID: 31738639 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 18, 2019 Category: ENT & OMF Authors: Kitoh R, Nishio SY, Usami SI Tags: Acta Otolaryngol Source Type: research

Transoral robotic surgery in the management of head and neck squamous cell cancer with unknown primary.
Conclusion: Addition of a superficial TORS-assisted BOT resection to the work-up of HNSCC-CUP frequently identifies primary lesions and alters the treatment for this group of patients even after thorough work-up. PMID: 31738643 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 18, 2019 Category: ENT & OMF Authors: Nilsson JS, Wahlberg P, Greiff L Tags: Acta Otolaryngol Source Type: research

Transcanal endoscopic ear surgery for traumatic ossicular injury.
Conclusion and significance: TEES for TOI yielded favorable audiometric results without any complication. TEES can provide an alternative method to manage TOI with the advantage of avoidance of skin incisions and mastoidectomy. PMID: 31707916 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 9, 2019 Category: ENT & OMF Authors: Kim MS, Chung J, Kang JY, Choi JW Tags: Acta Otolaryngol Source Type: research

Frequency analyses of posturography using logarithmic translation.
Conclusions: Logarithmic power-spectral data distribution could provide an age- and disease-specific novel and visually-comprehensible parameter. PMID: 31709868 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 9, 2019 Category: ENT & OMF Authors: Watanabe H, Makabe A, Hirai C, Takeda T, Honda K, Demura S, Tsutsumi T Tags: Acta Otolaryngol Source Type: research

Localization of melatonin and its receptors (melatonin 1a and 1b receptors) in the mouse inner ear.
Conclusion and significance: The present findings show that melatonin and its receptors (MT1a and MT1b) are present in the inner ear, thus supporting the hypothesis that melatonin plays a physiological role in the inner ear. PMID: 31561736 [PubMed - in process] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 29, 2019 Category: ENT & OMF Authors: Takumida M, Anniko M Tags: Acta Otolaryngol Source Type: research

Progression of hearing loss and choice of hearing aids by patients in their 60s, 70s, and 80s and older: experience in the Japanese super-aged era.
Conclusions and significance: The clinical picture of patients with SNHL in their 70s and 80s differs because progression accelerates exponentially through these ages. HAs can be recommended to older adult patients in all the age groups. PMID: 31560242 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 27, 2019 Category: ENT & OMF Authors: Maeda Y, Kariya S, Fujimoto S, Sugaya A, Kataoka Y, Nakagawa A, Tanaka S, Hosokawa N, Nishizaki K Tags: Acta Otolaryngol Source Type: research

Comparative outcomes of extracapsular dissection and superficial parotidectomy.
Conclusion and significance: ECD procedure was found to be as successful as SP in the selected patient group in approach to the pathologically proven and single benign parotid masses with similar recurrence and lower complication rates compared to the SP. PMID: 31560243 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 27, 2019 Category: ENT & OMF Authors: Ozturk K, Ozturk A, Turhal G, Kaya I, Akyildiz S, Uluoz U Tags: Acta Otolaryngol Source Type: research

Comparison of the development of early auditory and preverbal skills in Mandarin-Speaking children with cochlear implants with and without additional disabilities.
Conclusions and significance: The development of early auditory and preverbal skills among CI-using children progressed more slowly in those with AD (CP, DD or WML) than in TD children, but the differences between the two groups gradually diminished over time. Nonverbal cognitive status has a positive effect on early auditory and preverbal abilities. PMID: 31560244 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 27, 2019 Category: ENT & OMF Authors: Zhao Y, Li Y, Long Y, Jin X, Zheng Z, Liu Y, Wang Y, Zheng J, Zhang J, Chen M, Hao J, Yang Y, Liu W, Liu H, Ni X Tags: Acta Otolaryngol Source Type: research

Current status of human papillomavirus positivity in oropharyngeal squamous cell carcinoma in Europe: a systematic review.
Conclusion/significance: The highest share of HPV-positive patients with up to 65% was found in Nordic countries. The lowest share was found in Central and Southern European countries. PMID: 31560260 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 27, 2019 Category: ENT & OMF Authors: Stjernstrøm KD, Jensen JS, Jakobsen KK, Grønhøj C, von Buchwald C Tags: Acta Otolaryngol Source Type: research

Sandwich technique for sigmoid sinus wall reconstruction for treatment of pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence.
Conclusions: The sandwich surgical technique for sinus wall reconstruction as a treatment for pulsatile tinnitus caused by sigmoid sinus diverticulum is safe and effective. PMID: 31561720 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 27, 2019 Category: ENT & OMF Authors: Sun J, Sun J Tags: Acta Otolaryngol Source Type: research

Clinical long-term effects of surgical treatment for intractable Meniere's disease: a more than 13-year follow-up after pressure treatment and further surgical treatment for intractable vertigo.
Conclusions and significance: It is of great importance for intractable Meniere's disease to select surgically combined treatment process including Meniett, ESD and TSCO to effectively control the attacks of vertigo and a long-term follow-up. PMID: 31556757 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 26, 2019 Category: ENT & OMF Authors: Liu F, Huang W, Chen K Tags: Acta Otolaryngol Source Type: research

Therapeutic efficacy of intralesional bleomycin injection for laryngopharyngeal haemangioma in adults.
Abstract Background: Head and neck haemangiomas in the pharynx and larynx are rare, and the injection of bleomycin is currently one of the effective treatments. However, data on the therapeutic efficacy of this treatment are scarce. Objectives: To evaluate the clinical efficacy of bleomycin injection in the treatment of laryngopharyngeal haemangioma in adults and determine factors affecting efficacy. Materials and Methods: The clinical data of 42 adult patients with laryngopharyngeal haemangioma treated by intralesional bleomycin injection were retrospectively analysed to evaluate the clinical efficacy. Two groups...
Source: Acta Oto-Laryngologica - September 26, 2019 Category: ENT & OMF Authors: Liu F, Xiao Y, Wang J Tags: Acta Otolaryngol Source Type: research

Efficacy of microsurgery in combined with topical-PDT in treating recurrent respiratory papillomatosis: compare JORRP with AORRP.
Abstract Background: Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat. Objective: To explore the efficacy of microsurgery in combined with Topical-PDT in treating recurrent respiratory papillomatosis. Materials and methods: Fifty patients with RRP were treated with microsurgery in combined with Topical-PDT. Medical document of each patient was retrospectively reviewed. Detailed clinical information, metrics of clinical course, and current results were evaluated. Results: Juvenile onset RRP (JORRP) might experience a more aggressive course than AORRP (adult onset RRP...
Source: Acta Oto-Laryngologica - September 26, 2019 Category: ENT & OMF Authors: Yang S, Zhou C, Sun B, Wang F, Han Z, Zhang H, Han J, Shen Y, Zhang J Tags: Acta Otolaryngol Source Type: research

ErbB1 and ErbB2 overexpression in patients with sinonasal inverted papilloma and inverted papilloma with squamous cell carcinoma in China.
This study aimed to investigate the expression of EGFR family members and their ligands in SNIP and IPwSCC and to analyze their correlations with SNIP histological grade and Krouse stage. Materials and methods: Data from 25 cases of inverted papilloma patients in China were collected and divided into 16 cases in the SNIP group and 9 in the IPwSCC group. In addition, eight cases of normal nasal mucosa (NNM) were collected and used as the control group. The expression levels of EGFR family members and their ligands in the NNM and SNIP groups and EGFR family members in the IPwSCC group were evaluated using immunohistochemistr...
Source: Acta Oto-Laryngologica - September 26, 2019 Category: ENT & OMF Authors: Li H, Hu L, Zhang H, Wang D Tags: Acta Otolaryngol Source Type: research