Carcinoma of Unknown Primary Research 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research
M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research
Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research
M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research
Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research
M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research
Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research
M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research
Survival Outcome in True Carcinoma of Unknown Primary (tCUP) with p16 + Cervical Metastasis
Conclusion Cervical metastasis with p16 overexpression is a significant prognostic factor of improved RFS after surgery in CUP. The prognostic significance of lymph node p16 positivity should be further studied. [...] Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, BrazilArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - October 23, 2023 Category: ENT & OMF Authors: Faisal, Muhammad Le, Nguyen-Son Grasl, Stefan Pammer, Johannes Janik, Stefan Heiduschka, Gregor Schratter-Sehn, Annemarie U. Franz, Peter K önigswieser, Meinhard Grasl, Matthaeus Ch. Erovic, Boban M. Tags: Original Research Source Type: research
Positive factors on survival of head and neck cancer of unknown primary: what the clinician can do
CONCLUSION AND SIGNIFICANCE: Aspects for clinical decision-making: Curative MST and SCC histology were the most significant predictors for improved OS. Categorizing LN into 1, 2-3, and >3 LNs was more significant than the traditional N classification. The addition of CT to curative MST has a stronger impact on survival than HPV and N classifications.PMID:37842931 | DOI:10.1080/00016489.2023.2265937 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - October 16, 2023 Category: ENT & OMF Authors: Firas Khalil Michael Koch Heinrich Iro Matti Sievert Marlen Haderlein Sabine Semrau Rainer Fietkau Abbas Agaimy Claudia Scherl Source Type: research
Management of Unknown Primary Head and Neck Cancer with Radiation Therapy in the Era of Human Papillomavirus (HPV): No Longer Cutting Down the Tree to Get an Apple
CONCLUSIONS: Prospective evidence is lacking, and the available studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in work-up, treatment, inclusion criteria, and follow-up. Regardless, advances in science and technology have ushered in more precise approaches with a high degree of customization, particularly given the increased proportion of patients presenting with human papillomavirus-related disease.PMID:37844736 | DOI:10.1016/j.radonc.2023.109952 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2023 Category: Radiology Authors: Allen M Chen Source Type: research
Positive factors on survival of head and neck cancer of unknown primary: what the clinician can do
CONCLUSION AND SIGNIFICANCE: Aspects for clinical decision-making: Curative MST and SCC histology were the most significant predictors for improved OS. Categorizing LN into 1, 2-3, and >3 LNs was more significant than the traditional N classification. The addition of CT to curative MST has a stronger impact on survival than HPV and N classifications.PMID:37842931 | DOI:10.1080/00016489.2023.2265937 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - October 16, 2023 Category: ENT & OMF Authors: Firas Khalil Michael Koch Heinrich Iro Matti Sievert Marlen Haderlein Sabine Semrau Rainer Fietkau Abbas Agaimy Claudia Scherl Source Type: research
Management of Unknown Primary Head and Neck Cancer with Radiation Therapy in the Era of Human Papillomavirus (HPV): No Longer Cutting Down the Tree to Get an Apple
CONCLUSIONS: Prospective evidence is lacking, and the available studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in work-up, treatment, inclusion criteria, and follow-up. Regardless, advances in science and technology have ushered in more precise approaches with a high degree of customization, particularly given the increased proportion of patients presenting with human papillomavirus-related disease.PMID:37844736 | DOI:10.1016/j.radonc.2023.109952 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2023 Category: Radiology Authors: Allen M Chen Source Type: research
Positive factors on survival of head and neck cancer of unknown primary: what the clinician can do
CONCLUSION AND SIGNIFICANCE: Aspects for clinical decision-making: Curative MST and SCC histology were the most significant predictors for improved OS. Categorizing LN into 1, 2-3, and >3 LNs was more significant than the traditional N classification. The addition of CT to curative MST has a stronger impact on survival than HPV and N classifications.PMID:37842931 | DOI:10.1080/00016489.2023.2265937 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - October 16, 2023 Category: ENT & OMF Authors: Firas Khalil Michael Koch Heinrich Iro Matti Sievert Marlen Haderlein Sabine Semrau Rainer Fietkau Abbas Agaimy Claudia Scherl Source Type: research
Management of Unknown Primary Head and Neck Cancer with Radiation Therapy in the Era of Human Papillomavirus (HPV): No Longer Cutting Down the Tree to Get an Apple
CONCLUSIONS: Prospective evidence is lacking, and the available studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in work-up, treatment, inclusion criteria, and follow-up. Regardless, advances in science and technology have ushered in more precise approaches with a high degree of customization, particularly given the increased proportion of patients presenting with human papillomavirus-related disease.PMID:37844736 | DOI:10.1016/j.radonc.2023.109952 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2023 Category: Radiology Authors: Allen M Chen Source Type: research
