Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research

M üllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Curr Oncol. 2023 Oct 5;30(10):9019-9027. doi: 10.3390/curroncol30100651.ABSTRACTClear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type clear cell carcinoma in a 37-year-old patient who had previously received a transplanted kidney from his father at age 11 (due to severe bilateral vesicoureteral reflux) and remained on chronic immunosuppression. The tumor was highly aggressive and demonstrated somatic mutations in NF2 and SETD2. Imagi...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: J Bryan Iorgulescu Leah K Shaw Asif Rashid Priya Rao Sreedhar Mandayam Keyur P Patel Kathleen M Schmeler Richard K Yang Pavlos Msaouel Source Type: research

Local Treatment Efficacy for Single-Area Squamous Cell Carcinoma of the Unknown Primary Site
Curr Oncol. 2023 Oct 20;30(10):9327-9334. doi: 10.3390/curroncol30100674.ABSTRACTThe prognosis for cancer of unknown primary site (CUP) is poor, and squamous cell carcinoma of the unknown primary site (SCCUP) is a rare histological type. CUP is often treated with aggressive multimodal treatments, while the treatment of single-area localized CUP remains controversial. We retrospectively reviewed the medical records of patients with CUP. SCCUP in women was classified according to several definitions. Based on the histologic type and site, they were classified into favorable and unfavorable subsets. We further divided SCCUP i...
Source: Current Oncology - October 27, 2023 Category: Cancer & Oncology Authors: Tomoko Kurita Mayu Yunokawa Yuji Tanaka Kota Okamoto Motoko Kanno Atsushi Fusegi Makiko Omi Sachiho Netsu Hidetaka Nomura Akiko Tonooka Hiroyuki Kanao Source Type: research