Carbon Monoxide Alleviates Post-ischemia-reperfusion Skeletal Muscle Injury and Systemic Inflammation
Biol Pharm Bull. 2024;47(4):868-871. doi: 10.1248/bpb.b23-00917.ABSTRACTRestoration of blood flow in skeletal muscle after a prolonged period of ischemia induces muscular ischemia-reperfusion injury, leading to local injury/dysfunction in muscles followed by systemic inflammatory responses. However, preventive/curative agents for skeletal muscle ischemia injury are unavailable in clinics to date. Increasing evidence has validated that carbon monoxide (CO) prevents the progression of ischemia-reperfusion injury in various organs owing to its versatile bioactivity. Previously, we developed a bioinspired CO donor, CO-bound re...
Source: Biological and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Kazuaki Taguchi Shigeru Ogaki Hitoshi Maeda Yu Ishima Hiroshi Watanabe Masaki Otagiri Toru Maruyama Source Type: research
Optimal planning and designing of microgrid systems with hybrid renewable energy technologies for sustainable environment in cities
This study aids decision-makers in formulating policies for integrating hybrid RE systems in urban areas, promoting sustainable energy generation.PMID:38644424 | DOI:10.1007/s11356-024-33254-5 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - April 21, 2024 Category: Environmental Health Authors: Peddakapu Kurukuri Mohd Rusllim Mohamed Pavan Harika Raavi Yogendra Arya Source Type: research
Carbon Monoxide Alleviates Post-ischemia-reperfusion Skeletal Muscle Injury and Systemic Inflammation
Biol Pharm Bull. 2024;47(4):868-871. doi: 10.1248/bpb.b23-00917.ABSTRACTRestoration of blood flow in skeletal muscle after a prolonged period of ischemia induces muscular ischemia-reperfusion injury, leading to local injury/dysfunction in muscles followed by systemic inflammatory responses. However, preventive/curative agents for skeletal muscle ischemia injury are unavailable in clinics to date. Increasing evidence has validated that carbon monoxide (CO) prevents the progression of ischemia-reperfusion injury in various organs owing to its versatile bioactivity. Previously, we developed a bioinspired CO donor, CO-bound re...
Source: Biological and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Kazuaki Taguchi Shigeru Ogaki Hitoshi Maeda Yu Ishima Hiroshi Watanabe Masaki Otagiri Toru Maruyama Source Type: research
Sex differences of post-Covid patients undergoing outpatient pulmonary rehabilitation
ConclusionBoth subjective symptoms such as fatigue and dyspnea and objective impairment in performance in pulmonary function were more frequently observed among women. Despite improvement throughout OPR in both women and men, the sex-gap in symptom load could not be closed as women less often achieved remission from functional impairment due to PCS. Intensified treatment of these symptoms should be considered in women undergoing rehabilitation for PCS. (Source: Biology of Sex Differences)
Source: Biology of Sex Differences - April 21, 2024 Category: Biology Source Type: research
Elucidating effects of the environmental pollutant benzo[a]pyrene [BaP] on cardiac arrhythmogenicity
Environmental pollution causes cardiovascular disease, heart failure, and arrythmias [1 –4]. Wildfire emissions are a complex mixture composed of particulate matter (PM), carbon monoxide, methane, nitrous oxide, and polyaromatic hydrocarbons, among others [5], which are linked to arrhythmias [6]. Benzo[a]pyrene is a polyaromatic hydrocarbon and known carcinogen in animal models and i s implicated in breast cancer, lung cancer, liver cancer, and skin cancer [7]. Therefore, the further impact of BaP on the cardiovascular system merits further investigation. (Source: Journal of Molecular and Cellular Cardiology)
Source: Journal of Molecular and Cellular Cardiology - April 20, 2024 Category: Cytology Authors: Johnson Y. Yang, Gema Mond éjar-Parreño, James W.S. Jahng, Yu Lu, Naomi Hamburg, Kari C. Nadeau, Daniel J. Conklin, Ronglih Liao, Mark Chandy, Joseph C. Wu Tags: Letter to the editor Source Type: research
Bio-based P-N flame retardant with ZIF-67 in-situ growth on flexible polyurethane foam with excellent fire safety performance
Chemosphere. 2024 Apr 17;357:142048. doi: 10.1016/j.chemosphere.2024.142048. Online ahead of print.ABSTRACTThe wide application of flexible polyurethane foam (FPUF) poses a giant challenge to human society in terms of fire prevention and environmental pollution. To solve this problem, the lignocellulose-based P-N flame retardant (LFPN) has been developed using mechanochemical methods. It was found that FPUF treated using LFPN exhibited good flame retardancy, but suffered from high smoke generation and toxicity. The hollow dodecahedral ZIF-67 has been used for smoke suppression catalysis, but the agglomeration phenomenon ma...
Source: Chemosphere - April 19, 2024 Category: Chemistry Authors: Yiwei Geng Rongjia Li Zexuan Zhao Gaoyuan Li Biyu Huang Xilei Chen Chuanmei Jiao Source Type: research
Bio-based P-N flame retardant with ZIF-67 in-situ growth on flexible polyurethane foam with excellent fire safety performance
Chemosphere. 2024 Apr 17;357:142048. doi: 10.1016/j.chemosphere.2024.142048. Online ahead of print.ABSTRACTThe wide application of flexible polyurethane foam (FPUF) poses a giant challenge to human society in terms of fire prevention and environmental pollution. To solve this problem, the lignocellulose-based P-N flame retardant (LFPN) has been developed using mechanochemical methods. It was found that FPUF treated using LFPN exhibited good flame retardancy, but suffered from high smoke generation and toxicity. The hollow dodecahedral ZIF-67 has been used for smoke suppression catalysis, but the agglomeration phenomenon ma...
Source: Chemosphere - April 19, 2024 Category: Chemistry Authors: Yiwei Geng Rongjia Li Zexuan Zhao Gaoyuan Li Biyu Huang Xilei Chen Chuanmei Jiao Source Type: research
Dynamic trend of lung fluid movement during exercise in heart failure: From lung imaging to alveolar-capillary membrane function
In chronic heart failure (HF), exercise-induced increase in pulmonary capillary pressure may cause an increase of pulmonary congestion, or the development of pulmonary edema. We sought to assess in HF patients the exercise-induced intra-thoracic fluid movements, by measuring plasma brain natriuretic peptide (BNP), lung comets and lung diffusion for carbon monoxide (DLCO) and nitric oxide (DLNO), as markers of hemodynamic load changes, interstitial space and alveolar-capillary membrane fluids, respectively. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 19, 2024 Category: Cardiology Authors: Beatrice Pezzuto, Mauro Contini, Giovanni Berna, Arianna Galotta, Greta Cattaneo, Riccardo Maragna, Paola Gugliandolo, Piergiuseppe Agostoni Source Type: research
Treatment of COVID-19-associated ARDS with umbilical cord-derived mesenchymal stromal cells in the STROMA-CoV-2 multicenter randomized double-blind trial: long-term safety, respiratory function, and quality of life
CONCLUSIONS: This study suggests a favorable safety profile for the use of intravenous UC-MSCs in the context of the first French wave of SARS-CoV-2-related moderate-to-severe acute respiratory distress syndrome, with no adverse effects observed at 1 year.PMID:38637891 | DOI:10.1186/s13287-024-03729-w (Source: Cell Research)
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Alexandre Sitbon Caroline Hauw-Berlemont Miryam Mebarki Nicholas Heming Julien Mayaux Jean-Luc Diehl Alexandre Demoule Djillali Annane Cl émence Marois Sophie Demeret Emmanuel Weiss Guillaume Voiriot Muriel Fartoukh Jean-Michel Constantin Bruno M égarba Source Type: research
Bio-Inspired Bimetallic Models for Electrochemical CO2 Reduction
Dalton Trans., 2024, Accepted Manuscript DOI: 10.1039/D4DT00858H, PaperWeifang Feng, Ying Xiong, Ping Zhang, Minghong Li, Yaping Zhang, Fei Li, Lin Chen Inspired by the carbon monoxide dehydrogenase (CODH) active site where two metal ions synergistically catalyze the interconversion between CO2 and CO, we have developed a family of rhenium dipyridine derivatives... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Dalton Trans. latest articles)
Source: RSC - Dalton Trans. latest articles - April 17, 2024 Category: Chemistry Authors: Weifang Feng Source Type: research
CO2 Valorization in Deep Eutectic Solvents
ChemSusChem. 2024 Apr 17:e202400197. doi: 10.1002/cssc.202400197. Online ahead of print.ABSTRACTThe deep eutectic solvent (DES) has emerged in recent years as a valuable medium for converting CO2 into valuable chemicals because of its easy availability, stability, and safety, and its capability to dissolve carbon dioxide. CO2 valorization in DES has evolved rapidly over the past 20 years. As well as being used as solvents for acid/base-promoted CO2 conversion for the production of cyclic carbonates and carbamates, DESs can be used as reaction media for electrochemical CO2 reduction for formic acid and CO. Among these produ...
Source: ChemSusChem - April 17, 2024 Category: Chemistry Authors: Zhenbo Guo Zhicheng Zhang Yuchen Huang Tianxing Lin Yixin Guo Liang-Nian He Tianfei Liu Source Type: research
Development and Performance Evaluation of Biomass-Based Injera Baking Gasifier Stove: A Case Study of Clean Cooking Technologies in Ethiopia
ScientificWorldJournal. 2024 Apr 8;2024:1524398. doi: 10.1155/2024/1524398. eCollection 2024.ABSTRACTThe primary energy source in Ethiopia is biomass. Over 80% of Ethiopians are rural dwellers who rely on biomass energy for lighting and cooking. In most parts of Ethiopia, injera is traditionally baked using an open fire, a three stone, or a device using woody biomass. These baking stoves have very low efficiency and consume a significant amount of fuel. Moreover, these traditional baking stoves have released large amounts of indoor air pollution, which has led to different types of health-related risks, especially for wome...
Source: The Scientific World Journal - April 17, 2024 Category: Science Authors: Dawit Tessema Ebissa Eshetu Getahun Source Type: research
CO2 Valorization in Deep Eutectic Solvents
ChemSusChem. 2024 Apr 17:e202400197. doi: 10.1002/cssc.202400197. Online ahead of print.ABSTRACTThe deep eutectic solvent (DES) has emerged in recent years as a valuable medium for converting CO2 into valuable chemicals because of its easy availability, stability, and safety, and its capability to dissolve carbon dioxide. CO2 valorization in DES has evolved rapidly over the past 20 years. As well as being used as solvents for acid/base-promoted CO2 conversion for the production of cyclic carbonates and carbamates, DESs can be used as reaction media for electrochemical CO2 reduction for formic acid and CO. Among these produ...
Source: ChemSusChem - April 17, 2024 Category: Chemistry Authors: Zhenbo Guo Zhicheng Zhang Yuchen Huang Tianxing Lin Yixin Guo Liang-Nian He Tianfei Liu Source Type: research
CO oxidation mechanism of silver-substituted Mo/Cu CO-dehydrogenase. Analogies and differences to the native enzyme
In this study, we employed QM/MM calculations to investigate whether the reaction mechanism of the silver-substituted enzyme is similar to that of the native enzyme. Our results suggest that the Ag-substituted enzyme can oxidize CO and release CO2 following the same reaction steps as the native enzyme, with a computed rate-limiting step of 10.4 kcal/mol, consistent with experimental findings. Surprisingly, lower activation energies for C-O bond formation have been found in the presence of silver. Furthermore, comparison of rate constants for reduction of copper- and silver-containing enzymes suggests a discrepancy in the t...
Source: Chemphyschem - April 17, 2024 Category: Chemistry Authors: Rovaletti Anna Giorgio Moro Cosentino Ugo Ulf Ryde Claudio Greco Source Type: research
Development and Performance Evaluation of Biomass-Based Injera Baking Gasifier Stove: A Case Study of Clean Cooking Technologies in Ethiopia
ScientificWorldJournal. 2024 Apr 8;2024:1524398. doi: 10.1155/2024/1524398. eCollection 2024.ABSTRACTThe primary energy source in Ethiopia is biomass. Over 80% of Ethiopians are rural dwellers who rely on biomass energy for lighting and cooking. In most parts of Ethiopia, injera is traditionally baked using an open fire, a three stone, or a device using woody biomass. These baking stoves have very low efficiency and consume a significant amount of fuel. Moreover, these traditional baking stoves have released large amounts of indoor air pollution, which has led to different types of health-related risks, especially for wome...
Source: The Scientific World Journal - April 17, 2024 Category: Science Authors: Dawit Tessema Ebissa Eshetu Getahun Source Type: research
