From a dirty breath to atherosclerosis: Ozone pollution and neutrophil extracellular traps (NETs)
Exposure to ambient ozone in healthy individuals (shown in the magnified alveolus, including the transfer of ozone via the alveolar-capillary membrane and the contact with circulating neutrophils) associates with an elevation in the pro-atherogenic immunothrombotic pathway of NETosis. Precise mechanisms, and the role of concomitant pollutants remain unknown. Abbreviations: particulate matter (PM), ultrafine particles (UFP), sulphur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), neutrophil extracellular traps (NETs), and red blood cells (RBC). (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Tyler Artner, Irene M. Lang Source Type: research

Roles of Nutrients in the Brain Development, Cognitive Function, and Mood of Dogs and Cats
Adv Exp Med Biol. 2024;1446:177-202. doi: 10.1007/978-3-031-54192-6_8.ABSTRACTThe brain is the central commander of all physical activities and the expression of emotions in animals. Its development and cognitive health critically depend on the neural network that consists of neurons, glial cells (namely, non-neuronal cells), and neurotransmitters (communicators between neurons). The latter include proteinogenic amino acids (e.g., L-glutamate, L-aspartate, and glycine) and their metabolites [e.g., γ-aminobutyrate, D-aspartate, D-serine, nitric oxide, carbon monoxide, hydrogen sulfide, and monoamines (e.g., dopamine, norep...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Guoyao Wu Source Type: research

End-tidal carbon monoxide concentrations measured within 48 hours of birth predict hemolytic hyperbilirubinemia
Journal of Perinatology, Published online: 16 April 2024; doi:10.1038/s41372-024-01967-7End-tidal carbon monoxide concentrations measured within 48 hours of birth predict hemolytic hyperbilirubinemia (Source: Journal of Perinatology)
Source: Journal of Perinatology - April 16, 2024 Category: Perinatology & Neonatology Authors: Xiaoqin Cheng Bingchun Lin Yong Yang Yanliang Yu Yongping Fu Chuanzhong Yang Source Type: research

Analysis of a Serious Adverse Reaction of Pulmonary Fibrosis Caused by Dronedarone
CONCLUSIONS: It is recommended that clinicians monitor the diffusion capacity of carbon monoxide and lung ventilation function of patients before and after using dronedarone for treatment. For patients with a history of amiodarone exposure, intermittent monitoring of chest X-rays and lung function is necessary. If lung function decreases, dronedarone should be immediately discontinued.PMID:38617895 | PMC:PMC11015333 | DOI:10.1016/j.curtheres.2024.100743 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Yuyan Chen Zhendong Fu Xue Wen Mingxia Zhang Qiong Min Peng Wang Jin Zhang Jun Ren Wenbin Li Rong Wang Source Type: research

Analysis of a Serious Adverse Reaction of Pulmonary Fibrosis Caused by Dronedarone
CONCLUSIONS: It is recommended that clinicians monitor the diffusion capacity of carbon monoxide and lung ventilation function of patients before and after using dronedarone for treatment. For patients with a history of amiodarone exposure, intermittent monitoring of chest X-rays and lung function is necessary. If lung function decreases, dronedarone should be immediately discontinued.PMID:38617895 | PMC:PMC11015333 | DOI:10.1016/j.curtheres.2024.100743 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Yuyan Chen Zhendong Fu Xue Wen Mingxia Zhang Qiong Min Peng Wang Jin Zhang Jun Ren Wenbin Li Rong Wang Source Type: research

Relation between resting spleen volume and apnea-induced increases in hemoglobin mass
CONCLUSION: Larger spleen volume is not associated with a greater rise in apneas-induced increases in Hbmass in non-apnea-trained healthy adults.PMID:38615355 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Jason M Keeler Hayden W Hess Erica Tourula Robert F Chapman Blair D Johnson Zachary J Schlader Source Type: research

Surviving cardiac arrest after carbon monoxide poisoning treated with hyperbaric oxygen therapy
Undersea Hyperb Med. 2024 First Quarter;51(1):37-40.ABSTRACTCarbon monoxide (CO) and cyanide poisoning are frequent causes of morbidity and mortality in cases of house and industrial fires. The 14th edition of guidelines from the Undersea and Hyperbaric Medical Society does not recommend hyperbaric oxygen (HBO2) treatment in those patients who have suffered a cardiac arrest and had to receive cardiopulmonary resuscitation. In this paper, we describe the case of a 31-year-old patient who received HBO2 treatment in the setting of cardiac arrest and survived.PMID:38615351 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Vladimir Bronshteyn Stephen M Hendriksen Samantha J Lee Christopher Logue Source Type: research

The significance of precisely regulating heme oxygenase-1 expression: Another avenue for treating age-related ocular disease?
Ageing Res Rev. 2024 Apr 12:102308. doi: 10.1016/j.arr.2024.102308. Online ahead of print.ABSTRACTAging entails the deterioration of the body's organs, including overall damages at both the genetic and cellular levels. The prevalence of age-related ocular disease such as macular degeneration, dry eye diseases, glaucoma and cataracts is increasing as the world's population ages, imposing a considerable economic burden on individuals and society. The development of age-related ocular disease is predominantly triggered by oxidative stress and chronic inflammatory reaction. Heme oxygenase-1 (HO-1) is a crucial antioxidant that...
Source: Ageing Research Reviews - April 14, 2024 Category: Genetics & Stem Cells Authors: Dong Wei ChengKang Qu Na Zhao SiYu Li Ning Pu Ye Tao ZongMing Song Source Type: research