Carboxyhemoglobin in Cardiac Surgery Patients and Its Association with Risk Factors and Biomarkers of Hemolysis
CONCLUSIONS: CO-Hb may represent a readily obtainable and frequently measured biomarker that has a moderate association with known biomarkers of and risk factors for hemolysis in on-pump cardiac surgery patients. These findings have potential clinical implications and warrant further investigation.PMID:38446702 | DOI:10.1213/ANE.0000000000006915 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - March 6, 2024 Category: Anesthesiology Authors: Akinori Maeda Dinesh Pandey Ryota Inokuchi Sofia Spano Anis Chaba Atthaphong Phongphithakchai Glenn Eastwood Hossein Jahanabadi Hung Vo Siven Seevanayagam Andrew Motley Rinaldo Bellomo Source Type: research
Pulmonary function testing in preoperative high-risk patients
ConclusionsOur screening program detected a relevant number of patients with previously unknown obstructive ventilatory disorders and impaired pulmonary gas exchange. This newly discovered sickness is associated with low metabolic equivalents and may influence perioperative outcomes. Whether optimized management of patients with previously unknown impaired lung function leads to a better outcome should be evaluated in multicenter studies.Trial registrationGerman Registry of Clinical Studies (DRKS00029337), registered on: June 22nd, 2022. (Source: Perioperative Medicine)
Source: Perioperative Medicine - March 5, 2024 Category: Surgery Source Type: research
Clinical correlates of a non-plexiform vasculopathy in patients diagnosed with idiopathic pulmonary arterial hypertension
This study reveals different vascular phenotypes within the current spectrum of patients diagnosed with IPAH, separated by clinical characteristics (age, sex, , history of cigarette smoking, and DLCO at diagnosis). Potential differences in underlying pathobiological mechanisms between patients with plexiform and non-plexiform / microvascular disease should be taken into account in future research strategies unravelling the pathophysiology of pulmonary hypertension and developing biology-targeted treatment approaches.PMID:38432552 | DOI:10.1016/j.chest.2024.02.046 (Source: Chest)
Source: Chest - March 3, 2024 Category: Respiratory Medicine Authors: Esther J Nossent Josien Smits Celine Seegers Lilian J Meijboom Anco Boonstra J Aman F S De Man Harm Jan Bogaard Teodora Radonic Peter Dorfm üller Anton Vonk Noordegraaf Source Type: research
The concept of interstitial pneumonia with autoimmune features (IPAF)
The objective of this classification is to better characterize these patients and improve their management.PMID:38433068 | DOI:10.1016/j.revmed.2024.02.005 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 3, 2024 Category: Internal Medicine Authors: J Bermudez P Habert B Coiffard Source Type: research
Clinical correlates of a non-plexiform vasculopathy in patients diagnosed with idiopathic pulmonary arterial hypertension
This study reveals different vascular phenotypes within the current spectrum of patients diagnosed with IPAH, separated by clinical characteristics (age, sex, , history of cigarette smoking, and DLCO at diagnosis). Potential differences in underlying pathobiological mechanisms between patients with plexiform and non-plexiform / microvascular disease should be taken into account in future research strategies unravelling the pathophysiology of pulmonary hypertension and developing biology-targeted treatment approaches.PMID:38432552 | DOI:10.1016/j.chest.2024.02.046 (Source: Chest)
Source: Chest - March 3, 2024 Category: Respiratory Medicine Authors: Esther J Nossent Josien Smits Celine Seegers Lilian J Meijboom Anco Boonstra J Aman F S De Man Harm Jan Bogaard Teodora Radonic Peter Dorfm üller Anton Vonk Noordegraaf Source Type: research
The concept of interstitial pneumonia with autoimmune features (IPAF)
The objective of this classification is to better characterize these patients and improve their management.PMID:38433068 | DOI:10.1016/j.revmed.2024.02.005 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 3, 2024 Category: Internal Medicine Authors: J Bermudez P Habert B Coiffard Source Type: research
Clinical correlates of a non-plexiform vasculopathy in patients diagnosed with idiopathic pulmonary arterial hypertension
This study reveals different vascular phenotypes within the current spectrum of patients diagnosed with IPAH, separated by clinical characteristics (age, sex, , history of cigarette smoking, and DLCO at diagnosis). Potential differences in underlying pathobiological mechanisms between patients with plexiform and non-plexiform / microvascular disease should be taken into account in future research strategies unravelling the pathophysiology of pulmonary hypertension and developing biology-targeted treatment approaches.PMID:38432552 | DOI:10.1016/j.chest.2024.02.046 (Source: Chest)
Source: Chest - March 3, 2024 Category: Respiratory Medicine Authors: Esther J Nossent Josien Smits Celine Seegers Lilian J Meijboom Anco Boonstra J Aman F S De Man Harm Jan Bogaard Teodora Radonic Peter Dorfm üller Anton Vonk Noordegraaf Source Type: research
The concept of interstitial pneumonia with autoimmune features (IPAF)
The objective of this classification is to better characterize these patients and improve their management.PMID:38433068 | DOI:10.1016/j.revmed.2024.02.005 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 3, 2024 Category: Internal Medicine Authors: J Bermudez P Habert B Coiffard Source Type: research
Clinical correlates of a non-plexiform vasculopathy in patients diagnosed with idiopathic pulmonary arterial hypertension
This study reveals different vascular phenotypes within the current spectrum of patients diagnosed with IPAH, separated by clinical characteristics (age, sex, , history of cigarette smoking, and DLCO at diagnosis). Potential differences in underlying pathobiological mechanisms between patients with plexiform and non-plexiform / microvascular disease should be taken into account in future research strategies unravelling the pathophysiology of pulmonary hypertension and developing biology-targeted treatment approaches.PMID:38432552 | DOI:10.1016/j.chest.2024.02.046 (Source: Chest)
Source: Chest - March 3, 2024 Category: Respiratory Medicine Authors: Esther J Nossent Josien Smits Celine Seegers Lilian J Meijboom Anco Boonstra J Aman F S De Man Harm Jan Bogaard Teodora Radonic Peter Dorfm üller Anton Vonk Noordegraaf Source Type: research
The concept of interstitial pneumonia with autoimmune features (IPAF)
The objective of this classification is to better characterize these patients and improve their management.PMID:38433068 | DOI:10.1016/j.revmed.2024.02.005 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 3, 2024 Category: Internal Medicine Authors: J Bermudez P Habert B Coiffard Source Type: research
Short-term effects of ambient gaseous air pollution on blood platelet mitochondrial DNA methylation and myocardial ischemia
CONCLUSIONS: Platelet mtDNA methylation levels are promising biomarkers of short-term exposure to ambient gaseous air pollution, and are likely implicated in the mechanism behind the association of ambient O3 pollution with adverse cardiovascular effects. L-Arg supplementation showed the potential to mitigate the adverse effects of ambient O3 pollution.PMID:38430585 | DOI:10.1016/j.envint.2024.108533 (Source: Environment International)
Source: Environment International - March 2, 2024 Category: Environmental Health Authors: Yunxing Jiang Juan Chen Liqiong Guo Yang Lan Ge Li Qisijing Liu Hongyu Li Furong Deng Xinbiao Guo Shaowei Wu Source Type: research
