Perception of iron deficiency from oral mucosa alterations that show a high prevalence of Candida infection.
CONCLUSION: The study demonstrates that oral mucosa alterations accompanying oral candidosis are a sensitive indicator of ID. All oral changes can be successfully ameliorated by iron therapy plus antifungals when candidosis exists. Investigating the origin of IDA is necessary, because it may be the first sign of a more serious disease, particularly malignancy.
PMID: 27133388 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - April 27, 2016 Category: Journals (General) Authors: Lu SY Tags: J Formos Med Assoc Source Type: research
In vitro Impact of Limited Exposure to Subtherapeutic Concentrations of Chlorhexidine Gluconate on the Adhesion-Associated Attributes of Oral Candida Species
Conclusions: Brief exposure to subtherapeutic concentrations of CG suppressed the adhesion to BEC, DAS and CSH of oral Candida species, indicating probable pharmacodynamics that may potentiate its antiseptic properties.Med Princ Pract (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 22, 2016 Category: Internal Medicine Source Type: research
Vulvovaginal Candidosis (excluding chronic mucocutaneous candidosis). Guideline of the German Society of Gynecology and Obstetrics (AWMF Registry No. 015/072, S2k Level, December 2013).
Authors: Mendling W, Friese K, Mylonas I, Weissenbacher ER, Brasch J, Schaller M, Mayser P, Effendy I, Ginter-Hanselmayer G, Hof H, Cornely O, Ruhnke M
PMID: 27065484 [PubMed - as supplied by publisher] (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - April 12, 2016 Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC
In this study, we assessed a variable number tandem repeat (VNTR) polymorphism in the NLRP3 gene that encodes a component of the inflammasome, processing the proinflammatory cytokines IL-1β and IL-18. A total of 270 RVVC patients and 583 healthy controls were analyzed, and increased diseases susceptibility was associated with the presence of the 12/9 genotype. Furthermore, functional studies demonstrate that IL-1β production at the vaginal surface is higher in RVVC patients bearing the 12/9 genotype compared to controls, whereas IL-1Ra levels were decreased and IL-18 levels remained unchanged. These findings suggest that...
Source: European Journal of Clinical Microbiology and Infectious Diseases - March 7, 2016 Category: Microbiology Source Type: research
Vulvovaginal candidosis: contemporary challenges and the future of prophylactic and therapeutic approaches
Summary
Vulvovaginal candidosis (VVC) is a common gynaecological disorder that is delineated by the inflammation of vaginal wall and it is caused by the opportunistic fungal pathogen Candida species. In fact, three out of every four women will experience at least one occasion of VVC during some point in their lives. Although uncomplicated VVC is relatively harmless, the complicated VVC such as recurrent attack often creates restlessness and depression in the patients, thus greatly affects their quality of life. Managements of VVC are usually associated with the use of antimycotic suppositories, topical cream or oral agents...
Source: Mycoses - January 14, 2016 Category: Research Authors: Shu Yih Chew, Leslie Thian Lung Than Tags: Review Article Source Type: research
Caspofungin‐induced in‐vitro post‐antifungal effect and its impact on adhesion related traits of oral Candida dubliniensis and Candida albicans isolates
ABSTRACT
Adhesion to buccal epithelial cells (BEC) and denture acrylic surfaces (DAS), germ tube (GT) formation and cell surface hydrophobicity (CSH) are all virulence traits involved in pathogenicity of Candida. Post‐antifungal effect (PAFE) also have a bearing on pathogenicity and virulence of Candida. Candida dubliniensis is associated with oral and systemic candidosis, which can be managed with caspofungin. There is no information on caspofungin‐induced PAFE and its impact on adhesion traits of C. dubliniensis isolates. Thus, the purpose of this investigation was to determine the in vitro PAFE on 20 C. dubliniensis...
Source: Microbiology and Immunology - January 1, 2016 Category: Microbiology Authors: Arjuna Nishantha Bandara Ellepola, Rachel Chandy, Zia Uddin Khan, Lakshman Perera Samaranayake Tags: Original Article Source Type: research
The involvement of upper airway in Wegener's granulomatosis - about four cases.
Authors: Sarău CA, Lighezan DF, Doroş IC, Ştefănescu EH, Iovănescu G, Balica NC, Horhat ID, Poenaru M
Abstract
The authors present four cases of Wegener's granulomatosis patients with multiorganic manifestation forms, but with a prevalent involvement in upper-airway. Granulomatosis diseases of the nose include bacterial infections (rhinoscleroma, tuberculosis, syphilis, lupus, and leprosy), fungal infections (rhinosporidiosis, aspergillosis, mucormycosis, candidosis, histoplasmosis, and blastomycosis) and diseases with unspecified etiology (Wegener's granulomatosis, mediofacial malignant granuloma, an...
Source: Romanian Journal of Morphology and Embryology - November 18, 2015 Category: Journals (General) Tags: Rom J Morphol Embryol Source Type: research
Oral primary localized amyloidosis in HIV-infected patients: the oral face of a described skin lesion
Oral primary localized amyloidosis should be considered in the diagnosis of oral white lesions such as hyperplastic candidosis, lichen planus and lichenoid reactions; it is not associated with antiretroviral therapy use, systemic involvement or malignant transformation. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - November 3, 2015 Category: Global & Universal Authors: Anaya-Saavedra, G., Ramirez-Amador, V., Valencia-Mayoral, P. Tags: Case reports Source Type: research
M25 * Oral candidosis in the oncology department of the University Hospital in Pisa: prospective observational study
(Source: Annals of Oncology)
Source: Annals of Oncology - October 26, 2015 Category: Cancer & Oncology Authors: Frediani, E., Vietina, A., Fambrini, S., Carfagno, P., Pardossi, C., Buonamini, I., Gambini, L., Giorgi, M., Losoni, C., Pacchini, P., Pozzi, P., Minutella, L., De Luca, G., Rossini, D., Romanini, A. Tags: Session M. Oncology nursing Source Type: research
Impact of brief exposure to antifungal agents on the post-antifungal effect and hemolysin activity of oral Candida albicans
Conclusions Brief exposure to sublethal concentrations of antifungal drugs appears to exert an antifungal effect by interfering with the growth as well as hemolysin production of C. albicans. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 18, 2015 Category: Dentistry Source Type: research
Analysis of the biofilm formation of after Photodithazine-mediated photodynamic therapy in vivo
This study evaluated the capacity of biofilm formation of C. albicans recovered from the tongues of murine model of oral candidosis1, after consecutive applications of Photodithazine® (PDZ) (100mg/L) associated with LED (660nm) light (37.5J/cm2). Mice with oral candidosis were treated with photodynamic therapy (PDT) and Nystatin (NYS). Next, fungal cells were recovered from the oral lesions and submitted to biofilm formation. The capacity of biofilm formation was analyzed by the cellular viability (CFU/mL), XTT assay and Violet Crystal staining assay (CV). (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - September 1, 2015 Category: Laser Surgery Authors: Juliana Cabrini Carmello, Gabriela Maria Balista Ferreira, Fernanda Alves, Ewerton Garcia de Oliveira Mima, Janaina Habib Jorge, Ana Cláudia Pavarina Source Type: research
Total biomass of multispecies-biofilm after Photodynamic Therapy mediated by nanoemulsion-phthalocyanine
This study evaluated the total biomass of multispecies-biofilm of Streptococcus mutans, Candida albicans and Candida glabrata submitted to Photodynamic Therapy (PDT) mediated by aluminum-chloride-phthalocyanine encapsulated in cationic nanoemulsion (FC-Cl-Al-NE) associated with 660nm-LED light. Standard suspensions (106–107CFU/mL) of these microorganisms were transferred to wells of microtiter plates for the multispecies-biofilm formation (48h at 37°C in candle jars). (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - September 1, 2015 Category: Laser Surgery Authors: Ewerton Garcia de Oliveira Mima, Bruna Camila Rosado, Paula Volpato Sanitá, Carlos Eduardo Vergani, Antônio Cláudio Tedesco, Ana Cláudia Pavarina Source Type: research
A 52-year-old man with heartburn and weight loss
A previously fit and well 52-year-old man presented to the hospital with a 3-month history of refractory heartburn and progressive weight loss (5 kg). After an initial response to empiric treatment with 20 mg omeprazole daily, heartburn relapsed and became refractory to proton pump inhibitor. His past medical history and physical examination were unremarkable. Upper endoscopy showed a thick white membrane in the distal part of the oesophagus, crossing the gastro-oesophageal junction (figure 1A); the mucosa surrounding the distal margin was slightly depressed but not reddened. An initial diagnosis of candidosis wa...
Source: Gut - July 9, 2015 Category: Gastroenterology Authors: Gizzi, G., Foschini, M. P., Fabbri, C., Fuccio, L. Tags: GUT Snapshot Editor ' s quiz: GI snapshot Source Type: research
New Strategies for Local Treatment of Vaginal Infections.
Abstract
Vaginal infections are extremely prevalent, particularly among reproductive aged women. Although not resulting in high mortality, these infections are associated with high levels of anxiety and depreciation of low quality of life. In most cases, topical treatment of vaginal infections has been shown to be at least as effective as oral treatment, resulting in higher local drug concentrations, with less drug interactions and adverse effects. Furthermore, the emergence of microbial resistance to chemotherapeutics and the difficulties in managing infection recurrences sustain the need for more effecti...
Source: Advanced Drug Delivery Reviews - July 2, 2015 Category: Drugs & Pharmacology Authors: Palmeira-de-Oliveira R, Palmeira-de-Oliveira A, Martinez-de-Oliveira J Tags: Adv Drug Deliv Rev Source Type: research
Organic Based Bio-sensor for Odor Detection in Gynecological Diseases
Publication date: 2015 Source:Materials Today: Proceedings, Volume 2, Issue 1 Author(s): Maria I. Marques , Joana Fonseca , João Gomes , Ana Palmeira-de-Oliveira , José Martinez-de-Oliveira , L. Pereira Odor sensors were fabricated by depositing organic polymeric semiconductor on screen-printed interdigitated electrodes. These sensors were tested with odors from different origins and in particular a culture of vaginal candidosis, in order the get insight about their use for a medical based diseases control. Both capacitive and resistive sensors were tested with different electrodes size/separations and composit...
Source: Materials Today: Proceedings - June 6, 2015 Category: Materials Science Source Type: research
