Early-career general practitioners ’ antibiotic prescribing for acute infections: a systematic review
ConclusionsEarly-career GPs prescribe fewer antibiotics than later-career GPs. However, there are still significant improvements to be made for common acute conditions, as their prescribing is higher than recommended benchmarks. Addressing antimicrobial resistance requires an ongoing worldwide effort and early-career GPs should be the target for long-term change. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - January 22, 2024 Category: Microbiology Source Type: research
Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air –liquid interface
Chronic obstructive pulmonary disease (COPD) has the highest increased risk due to household air pollution arising from biomass fuel burning. However, knowledge on COPD patho-mechanisms is mainly limited to to... (Source: Respiratory Research)
Source: Respiratory Research - January 20, 2024 Category: Respiratory Medicine Authors: Swapna Upadhyay, Mizanur Rahman, Selina Rinaldi, Jeremy Koelmel, Elizabeth Z. Lin, Padukudru Anand Mahesh, Johannes Beckers, Gunnar Johanson, Krystal J. Godri Pollitt, Lena Palmberg, Martin Irmler and Koustav Ganguly Tags: Research Source Type: research
Molecular changes underlying pulmonary emphysema and chronic bronchitis in Chronic Obstructive Pulmonary Disease: An updated review
Histol Histopathol. 2023 Dec 28:18699. doi: 10.14670/HH-18-699. Online ahead of print.ABSTRACTThe aim of this review is to update and synthesize the molecular mechanisms that lead to the heterogeneous effect on tissue remodeling observed in the two most important clinical phenotypes of chronic obstructive pulmonary disease (COPD), pulmonary emphysema (PE) and chronic bronchitis (CB). Clinical and experimental evidence suggests that this heterogeneous response to promote PE, CB, or both, is related to differentiated genetic, epigenetic, and molecular conditions. Specifically, a tendency toward PE could be related to a varia...
Source: Histology and Histopathology - January 16, 2024 Category: Cytology Authors: Elia A Baltazar-Garc ía Belinda Vargas-Guerrero Luz E Gasca-Lozano Carmen M Gurrola-D íaz Source Type: research
The associations between different types of infections and circadian preference and shift work
In conclusion, neither circadian preference nor shift work seemed to be strongly associated with risk of infections, except for venereal disease (more common in evening types) and influenza-like illness (more common in night workers). Longitudinal studies are needed for causal inferences.PMID:38221779 | DOI:10.1080/07420528.2024.2303986 (Source: Chronobiology International)
Source: Chronobiology International - January 15, 2024 Category: Biology Authors: Bj ørn Bjorvatn Siri Waage Knut Erik Emberland Sverre Litleskare Ingrid K Rebnord Ingeborg Forthun Guri Rortveit Source Type: research
Molecules, Vol. 29, Pages 421: Trollius chinensis Bunge: A Comprehensive Review of Research on Botany, Materia Medica, Ethnopharmacological Use, Phytochemistry, Pharmacology, and Quality Control
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Xiubo Liu
Trollius chinensis Bunge, a perennial herb belonging to the Ranunculaceae family, has been extensively used in traditional Chinese medicine. Documented in the Supplements to the Compendium of Materia Medica, its medicinal properties encompass a spectrum of applications, including heat clearance, detoxification, alleviation of oral/throat sores, earaches, eye pain, cold-induced fever, and vision improvement. Furthermore, T. chinensis is used in clinical settings to treat upper respiratory infections, pharyngitis, tonsillitis, esoenteritis, canker, bronchitis, etc. It is mainly used to treat inflammation, s...
Source: Molecules - January 15, 2024 Category: Chemistry Authors: Lianqing He Zhen Wang Jiaxin Lu Chen Qin Jiajun He Weichao Ren Xiubo Liu Tags: Review Source Type: research
Mechanism of Tonifying Spleen-lung Recipe in the Treatment of Chronic Bronchitis Based on Network Pharmacology and Observational Data
CONCLUSION: TSLR had a good therapeutic effect on chronic bronchitis patients, which might be related to the fact that the natural active components in TSLR inhibit inflammation by regulating the expression of proteins related to PI3K-AKT and TNF signaling pathways.PMID:38213144 | DOI:10.2174/0113862073274028231213105142 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 12, 2024 Category: Chemistry Authors: Hongjin Wu Shenguang Li Xiaomei Du Kaigong Zhu Jing Li Source Type: research
Four cold-causing coronaviruses may provide clues to COVID ’s future
Over a few weeks in November 1889, a respiratory disease attacked half the residents of St. Petersburg, Russia, and it soon began to race through Europe and the rest of the world. Two years later, in a spectacularly
detailed book
, a British medical officer, H. Franklin Parsons, described what was dubbed the “Russian influenza” epidemic, which raged until 1894. People seemed to spread the disease before developing symptoms, the young did not suffer as much as the old, a dry cough was common among the ill, some had a “perversion of taste and smell,” and deaths rose. Suspicions ran high that a pathogen had ...
Source: Science of Aging Knowledge Environment - January 11, 2024 Category: Geriatrics Source Type: research
