Viruses, Vol. 16, Pages 481: The Effect of Global Spread, Epidemiology, and Control Strategies on the Evolution of the GI-19 Lineage of Infectious Bronchitis Virus
This study leverages this scenario to explore how different environments may influence virus evolution. Through the analysis of the complete S1 sequence, four datasets were identified, comprising strains of monophyletic clades circulating in different continents or countries (e.g., Asia vs. Europe and China vs. Thailand), indicative of single introduction events and independent evolution. The population dynamics and evolutionary rate variation over time, as well as the presence and intensity of selective pressures, were estimated and compared across these datasets. Since the lineage origin (approximately in the mid-20th ce...
Source: Viruses - March 20, 2024 Category: Virology Authors: Giovanni Franzo Giulia Faustini Claudia Maria Tucciarone Francesca Poletto Francesca Tonellato Mattia Cecchinato Matteo Legnardi Tags: Article Source Type: research
Chemical characterization, multivariate analysis and comparison of biological activities of different parts of Fraxinus mandshurica
This study establishes an identification and evaluation method applicable to phytochemistry of different origins, which is a guideline for quality control, origin evaluation and clinical application of traditional medicinal plants. This is also an unprecedented study on the identification of the chemical composition of different parts of F. mandshurica, characteristic compounds and the inhibition of enzyme activity of extracts from different parts.PMID:38501361 | DOI:10.1002/bmc.5861 (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - March 19, 2024 Category: Biomedical Science Authors: Jianjin Guo Shaojing Liu Yan Guo Lu Bai Chi-Tang Ho Naisheng Bai Source Type: research
Ceftriaxone-induced severe hemolytic anemia, renal calculi, and cholecystolithiasis in a 3-year-old child: a case report and literature review
This report details a rare and severe case of ceftriaxone-induced severe immune hemolytic anemia (IHA), hemolytic crisis, myocardial injury, liver injury, renal calculi, and cholecystolithiasis in a previously healthy 3-year-old child. The child, treated for bronchitis, experienced sudden pallor, limb stiffness, and altered consciousness following the fifth day of ceftriaxone infusion, with hemoglobin (Hb) levels precipitously dropping to 21 g/L. Immediate cessation of ceftriaxone and the administration of oxygen therapy, blood transfusion, intravenous immunoglobulin (IVIG), and corticosteroids led to a gradual recovery. ...
Source: Frontiers in Pharmacology - March 15, 2024 Category: Drugs & Pharmacology Source Type: research
Analysis of the Risk Factors for Plastic Bronchitis in Children with Severe Adenovirus Pneumonia: A Retrospective Study
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - March 14, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Characterization of chitosan/Persian gum nanoparticles for encapsulation of Nigella sativa extract as an antiviral agent against avian coronavirus
Int J Biol Macromol. 2024 Mar 9:130749. doi: 10.1016/j.ijbiomac.2024.130749. Online ahead of print.ABSTRACTThe aim of this study was to investigate the physicochemical characteristics of nanoparticles formed by the ionic gelation method between chitosan and water-soluble fraction of Persian gum (WPG) for encapsulation of Nigella sativa extract (NSE) as an antiviral agent. Our findings revealed that the particle size, polydispersity index (PDI), and zeta potential of the particles were in the range of 316.7-476.6 nm, 0.259-0.466, and 37.0-58.1 mV, respectively. The amounts of chitosan and WPG as the wall material and the NS...
Source: International Journal of Biological Macromolecules - March 11, 2024 Category: Biochemistry Authors: Mohammad Hadian Morteza Fathi Ali Mohammadi Mohammad Hadi Eskandari Mehdi Asadsangabi Khadijeh Pouraghajan Majid Shohrati Masoomeh Mohammadpour Mohammad Samadi Source Type: research
Characterization of chitosan/Persian gum nanoparticles for encapsulation of Nigella sativa extract as an antiviral agent against avian coronavirus
Int J Biol Macromol. 2024 Mar 9:130749. doi: 10.1016/j.ijbiomac.2024.130749. Online ahead of print.ABSTRACTThe aim of this study was to investigate the physicochemical characteristics of nanoparticles formed by the ionic gelation method between chitosan and water-soluble fraction of Persian gum (WPG) for encapsulation of Nigella sativa extract (NSE) as an antiviral agent. Our findings revealed that the particle size, polydispersity index (PDI), and zeta potential of the particles were in the range of 316.7-476.6 nm, 0.259-0.466, and 37.0-58.1 mV, respectively. The amounts of chitosan and WPG as the wall material and the NS...
Source: International Journal of Biological Macromolecules - March 11, 2024 Category: Biochemistry Authors: Mohammad Hadian Morteza Fathi Ali Mohammadi Mohammad Hadi Eskandari Mehdi Asadsangabi Khadijeh Pouraghajan Majid Shohrati Masoomeh Mohammadpour Mohammad Samadi Source Type: research
Association between carotenoids and the prevalence of chronic obstructive pulmonary disease in the United States
Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition characterized by persistent respiratory symptoms and restricted airflow resulting from exposure to harmful particles and gases.1 Chronic bronchitis and emphysema are the two main characteristics of COPD due to abnormalities in the airways or alveoli.2 COPD is a major reason for hospital admission and has been a public health issue.3 Several studies have revealed that inflammation plays a pivotal role in the development of COPD. (Source: Heart and Lung)
Source: Heart and Lung - March 7, 2024 Category: Intensive Care Authors: Qiong Huang, Zhenyu Peng, Siqi Li, Wenbin Nan, Baimei He Source Type: research
