Systemic Lupus Erythematosus-related Lung Disease
Semin Respir Crit Care Med DOI: 10.1055/s-0044-1782653Systemic Lupus Erythematosus (SLE) is a multifaceted, multisystem autoimmune disorder with diverse clinical expressions. While prevalence reports vary widely, pulmonary involvement accounts for significant morbidity and mortality in SLE. This comprehensive review explores the spectrum of pulmonary disease in SLE, including upper airway manifestations (e.g., laryngeal affection), lower airway conditions (e.g., bronchitis, bronchiolitis, bronchiectasis), parenchymal diseases (e.g., interstitial lung disease, acute lupus pneumonitis, diffuse alveolar hemorrhage), pleural d...
Source: Seminars in Respiratory and Critical Care Medicine - March 28, 2024 Category: Respiratory Medicine Authors: Bendstrup, Elisabeth Lynn, Evelyn Troldborg, Anne Tags: Review Article Source Type: research

Viruses, Vol. 16, Pages 515: An Amplicon-Based Application for the Whole-Genome Sequencing of GI-19 Lineage Infectious Bronchitis Virus Directly from Clinical Samples
Hye-Ryoung Kim Infectious bronchitis virus (IBV) causes a highly contagious respiratory disease in chickens, leading to significant economic losses in the poultry industry worldwide. IBV exhibits a high mutation rate, resulting in the continuous emergence of new variants and strains. A complete genome analysis of IBV is crucial for understanding its characteristics. However, it is challenging to obtain whole-genome sequences from IBV-infected clinical samples due to the low abundance of IBV relative to the host genome. Here, we present a novel approach employing next-generation sequencing (NGS) to directly sequence th...
Source: Viruses - March 27, 2024 Category: Virology Authors: Hoang Duc Le Tuyet Ngan Thai Jae-Kyeom Kim Hye-Soon Song Moon Her Xuan Thach Tran Ji-Ye Kim Hye-Ryoung Kim Tags: Communication Source Type: research

A review on the traditional applications, phytochemistry, and pharmacology of the genus Physochlaina G. Don
Chem Biodivers. 2024 Mar 26:e202400394. doi: 10.1002/cbdv.202400394. Online ahead of print.ABSTRACTPhysochlaina is a genus of flowering plants belonging to the family Solanaceae and consists of 10 species distributed in various Asian countries. The species of the genus have been traditionally used to cure a variety of illnesses due to their highly valuable medicinal properties, including cancer, asthma, cough, weakness, stomachache, diarrhea, swelling, spasms, toothache, boils, ulcers, rheumatic pain, chronic bronchitis, gastric problems, abdominal pain, palpitation, and insomnia. The species have gained significant attent...
Source: Chemistry and Biodiversity - March 26, 2024 Category: Biochemistry Authors: Younas Rasheed Tantray Ishrat Jan Irshad Mohiuddin Preeti Gorla Charul Anand Jagdesh Chandra Arya Shahnawaz Ahmad Bhat Vijay Kumar Shiddamallayya Nagayya Rabinaryana Acharya Source Type: research

Giant bullous emphysema successfully treated with percutaneous drainage followed by resection: A case complicated by lung cancer diagnosed by intraoperative biopsy
We report a case of bilateral GBE with multiple lung nodules that was treated with percutaneous drainage followed by bullectomy, and was successfully diagnosed with lung cancer by intraoperative needle biopsy. AbstractWe present a case of bilateral giant bullous emphysema (GBE) with rapidly progressive dyspnea. The dyspnea was thought to be due to tension bullae caused by the check valve mechanism in COVID-19 bronchitis. Multiple nodules were also detected on both sides of the lung. As the patient had poor pulmonary reserve for surgical bullectomy, we first performed percutaneous intracavitary drainage. Prior to this proce...
Source: Respirology Case Reports - March 25, 2024 Category: Respiratory Medicine Authors: Sachie Hasegawa, Mako Yokoyama, Toshihide Inui, Hiroaki Ishikawa, Hiroko Watanabe, Masaki Kimura, Susumu Yoshida, Tohru Sakamoto Tags: CASE REPORT Source Type: research

Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report
Respir Med Case Rep. 2024 Mar 13;48:102010. doi: 10.1016/j.rmcr.2024.102010. eCollection 2024.ABSTRACTCarbapenem-resistant Acinetobacter baumannii (CR-AB) is rarely found in community respiratory infections, and there are currently no reports of hemorrhagic bronchitis caused by its infection. This work presents a case of bronchial bleeding in a diabetic patient who acquired a community-acquired infection of CR-AB. Treatment with levofloxacin was unsuccessful, as the patient's hemoptysis symptoms recur. The patient was treated with minocycline based on the drug sensitivity test, resulting in the disappearance of hemoptysis ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Zifang Li Yu Sheng Dongdong Huang Source Type: research

Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report
Respir Med Case Rep. 2024 Mar 13;48:102010. doi: 10.1016/j.rmcr.2024.102010. eCollection 2024.ABSTRACTCarbapenem-resistant Acinetobacter baumannii (CR-AB) is rarely found in community respiratory infections, and there are currently no reports of hemorrhagic bronchitis caused by its infection. This work presents a case of bronchial bleeding in a diabetic patient who acquired a community-acquired infection of CR-AB. Treatment with levofloxacin was unsuccessful, as the patient's hemoptysis symptoms recur. The patient was treated with minocycline based on the drug sensitivity test, resulting in the disappearance of hemoptysis ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Zifang Li Yu Sheng Dongdong Huang Source Type: research

Differential response to roflumilast in patients with chronic obstructive pulmonary disease: real-world evidence
CONCLUSIONS: The benefit of roflumilast in moderate-to-severe exacerbations was estimated to be greater in specific subgroups of patients with COPD. Personalised approaches to roflumilast based on clinical phenotypes would be effective for COPD.PMID:38505074 | PMC:PMC10944795 | DOI:10.21037/jtd-23-1129 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Hyun Woo Lee Jiyu Sun Hyo-Jin Lee Jung-Kyu Lee Tae Yeon Park Eun Young Heo Chin Kook Rhee Deog Kyeom Kim Source Type: research