Determining efficacy of dynamic multimedia bowel preparation instructions versus standard instructions on adenoma detection and patient reported measures (DIGICLEAN trial): a study protocol for a multicentre, colonoscopist-blinded, randomised controlled trial
BMJ Open. 2023 Jul 21;13(7):e073843. doi: 10.1136/bmjopen-2023-073843.ABSTRACTINTRODUCTION: Colonoscopy plays important roles in bowel cancer screening and treatment. Poor bowel preparation occurs in 20-25% of colonoscopies. This negatively impacts adenoma and sessile serrated lesion detection rates, procedural time, requirement for repeat colonoscopies, healthcare costs and likelihood of patient withdrawal from screening programmes. It is unclear whether a combination of multimedia modalities can improve bowel preparation quality, adenoma detection rates and patient-reported measures in those undergoing colonoscopy assess...
Source: Cancer Control - July 21, 2023 Category: Cancer & Oncology Authors: Michael Au Patrick Low Michael Rennie Marriam Mohseni Yang Song Narae Kim Brandon Baraty Nikola Mitrev Emily He Vincent Ho Rupert Leong Viraj Kariyawasam Source Type: research
Determining efficacy of dynamic multimedia bowel preparation instructions versus standard instructions on adenoma detection and patient reported measures (DIGICLEAN trial): a study protocol for a multicentre, colonoscopist-blinded, randomised controlled trial
Introduction
Colonoscopy plays important roles in bowel cancer screening and treatment. Poor bowel preparation occurs in 20–25% of colonoscopies. This negatively impacts adenoma and sessile serrated lesion detection rates, procedural time, requirement for repeat colonoscopies, healthcare costs and likelihood of patient withdrawal from screening programmes. It is unclear whether a combination of multimedia modalities can improve bowel preparation quality, adenoma detection rates and patient-reported measures in those undergoing colonoscopy assessment.
Methods
The DIGICLEAN trial is a prospective, parallel, multicentr...
Source: BMJ Open - July 21, 2023 Category: General Medicine Authors: Au, M., Low, P., Rennie, M., Mohseni, M., Song, Y., Kim, N., Baraty, B., Mitrev, N., He, E., Ho, V., Leong, R., Kariyawasam, V. Tags: Open access, Gastroenterology and hepatology Source Type: research
Geographical and spatial variations in bowel cancer screening participation, Australia, 2015 –2020
ConclusionsDespite having a well-structured evidence-based government funded national bowel cancer screening program, the substantial spatial variation in participation rates highlights the importance of accounting for the unique characteristics of specific geographical regions and their inhabitants. Identifying the reasons for geographical disparities could inform interventions to achieve more equitable access and a higher overall bowel screening uptake. (Source: PLoS One)
Source: PLoS One - July 20, 2023 Category: Biomedical Science Authors: Paramita Dasgupta Source Type: research
Process, structural, and outcome quality indicators to support perioperative opioid stewardship: a rapid review
AbstractOpioids are effective analgesics but can cause harm. Opioid stewardship is key to ensuring that opioids are used effectively and safely. There is no agreed set of quality indicators relating to the use of opioids perioperatively. This work is part of the Yorkshire Cancer Research Bowel Cancer Quality Improvement programme and aims to develop useful quality indicators for the improvement of care and patient outcomes at all stages of the perioperative journey.A rapid review was performed to identify original research and reviews in which quality indicators for perioperative opioid use are described. A data tool was d...
Source: Perioperative Medicine - July 10, 2023 Category: Surgery Source Type: research
High yield of surveillance in patients diagnosed with constitutional mismatch repair deficiency
Conclusion
The study suggests a beneficial effect of surveillance of the digestive tract and brains. (Source: Journal of Medical Genetics)
Source: Journal of Medical Genetics - June 21, 2023 Category: Genetics & Stem Cells Authors: Ghorbanoghli, Z., van Kouwen, M., Versluys, B., Bonnet, D., Devalck, C., Tinat, J., Januszkiewicz-Lewandowska, D., Costas, C. C., Cottereau, E., Hardwick, J. C. H., Wimmer, K., Brugieres, L., Colas, C., Vasen, H. F. A. Tags: Cancer genetics Source Type: research
Cancers, Vol. 15, Pages 2766: Optimising Outcomes and Surveillance Strategies of Rectal Neuroendocrine Neoplasms
K. Ramage
Rectal neuroendocrine neoplasms are increasing in incidence, in part due to increased endoscopic procedures being performed for bowel cancer screening. Whilst most of these lesions are low-grade well-differentiated neuroendocrine tumours, they can have a varied clinical behaviour. Frequently, these lesions are incorrectly characterised at endoscopy and, therefore, incompletely excised using standard polypectomy techniques. Furthermore, some cases are not fully staged prior to or post resection. In this article we discuss the endoscopic and surgical options available to improve the likelihood of achieving an R...
Source: Cancers - May 15, 2023 Category: Cancer & Oncology Authors: Rajaventhan Srirajaskanthan Dominique Clement Sarah Brown Mark R. Howard John K. Ramage Tags: Review Source Type: research
Colorectal cancer and advanced adenoma incidence during post-polypectomy surveillance: a national cohort study in the English Bowel Cancer Screening Programme
Conclusion This large, national analysis found low levels of CRC in those undergoing surveillance and low advanced adenoma yield in most subgroups. Less intensive surveillance in some subgroups is warranted, and surveillance may be avoided in those with a single large adenoma. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Endoscopy)
Source: Endoscopy - April 25, 2023 Category: Gastroenterology Authors: Bonnington, Stewart N. Hungin, A. Pali S. Nickerson, Claire Wright, Suzanne Sharp, Linda Rutter, Matthew D. Tags: Original article Source Type: research
Evaluating changes to home bowel cancer screening kits: an end-user perspective study
ConclusionThese findings highlight multiple ways in which bowel cancer screening kits can be changed to increase usability for invitees of national bowel cancer screening programs. Findings have implications for all screening programs that use immunochemical-based bowel cancer screening kits. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - April 21, 2023 Category: Cancer & Oncology Source Type: research
Risk Factors of Cancer in Paediatric-onset Inflammatory Bowel Disease in Denmark and Finland
CONCLUSIONS: In this nation-wide study, covering all pIBD patients from Denmark and Finland, we found that pIBD patients treated with thiopurines had an increased risk of TAC.PMID:36961906 | DOI:10.1097/MPG.0000000000003781 (Source: Cancer Control)
Source: Cancer Control - March 24, 2023 Category: Cancer & Oncology Authors: Mikkel Malham Sabine Jansson Petter Malmborg Ola Olen Anders Paerregaard Lauri J Virta Christian Jakobsen Kaija-Leena Kolho Vibeke Wewer Source Type: research
Healthy eating and active lifestyle after bowel cancer: feasibility of a randomised controlled trial
Rationale: Evidence from cohort studies indicates that a healthy lifestyle can improve cancer survival.1,2 However, evidence from randomised controlled trials is lacking.3 The study aimed to investigate the feasibility of HEAL ABC lifestyle intervention in patients after colorectal cancer (CRC) surgery and treatment. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - March 23, 2023 Category: Nutrition Authors: J. Sremanakova, A.M. Sowerbutts, C. Todd, L. Pearce, V. Kenyon, D. Leiberman, H. Ashby, G. Harrison, J. McLaughlin, A. Ramesh, J. Hill, R. Cooke, M. Gittins, S. Burden Source Type: research
Things I need you to know: a qualitative analysis of advice-giving statements in early-onset colorectal cancer patients personal accounts published online
Conclusion
Healthcare barriers to, and facilitators of, patient self-advocacy may be indicators of quality EORC care. There is a need for greater awareness of the impact of age bias on the responsiveness of clinicians and healthcare services in EOCRC care. Our findings support the development of EOCRC-specific PREMs that can guide age-appropriate policy and practice for this newly identified patient population. (Source: BMJ Open)
Source: BMJ Open - March 22, 2023 Category: General Medicine Authors: Lamprell, K., Fajardo-Pulido, D., Arnolda, G., Owais, S. S., Nic Giolla Easpaig, B., Tran, Y., Liauw, W., Braithwaite, J. Tags: Open access, General practice / Family practice Source Type: research
Differential to Terminal Ileitis: Terminal Ileum Neuroendocrine Tumor Identified on Screening Colonoscopy
Conclusion: Terminal ileitis encompasses a host of pathologic processes, including inflammatory states, infectious disease, malignancy, and vasculitis. Importantly, small bowel cancer is an increasing cause of terminal ileitis. Screening colonoscopy with ileal intubation can be a valuable tool for early detection of these lesions.PMID:36936484 | PMC:PMC10016213 | DOI:10.31486/toj.22.0035 (Source: Ochsner Journal)
Source: Ochsner Journal - March 20, 2023 Category: General Medicine Authors: Alp S Kahveci Muhammad F Mubarak Isma Perveze Ebubekir S Daglilar Source Type: research
