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The association of perioperative blood transfusion with survival outcomes after major cancer surgery: a population-based cohort study in South Korea
ConclusionWe identified potential risk factors for perioperative blood transfusions. Blood transfusion is associated with an increased 90-day mortality risk after major cancer surgery. (Source: Surgery Today)
Source: Surgery Today - January 4, 2024 Category: Surgery Source Type: research

Increasing bowel cancer screening using SMS in general practice: the SMARTscreen trial
CONCLUSION: The SMS increased NBCSP kit return in 50-to-60-year-old general practice patients. This finding informed a larger trial -SMARTERscreen- to test this intervention in a broader Australian population.PMID:38164588 | DOI:10.3399/BJGP.2023.0230 (Source: The British Journal of General Practice)
Source: The British Journal of General Practice - January 2, 2024 Category: Primary Care Authors: Jennifer G McIntosh Mark A Jenkins Anna Wood Patty Chondros Tina Campbell Edweana Wenkart Clare O'Reilly Ian Dixon Julie Toner Javiera Martinez Gutierrez Linda Govan Jon Emery Source Type: research

Increasing bowel cancer screening using SMS in general practice: the SMARTscreen trial
CONCLUSION: The SMS increased NBCSP kit return in 50-to-60-year-old general practice patients. This finding informed a larger trial -SMARTERscreen- to test this intervention in a broader Australian population.PMID:38164588 | DOI:10.3399/BJGP.2023.0230 (Source: Cancer Control)
Source: Cancer Control - January 2, 2024 Category: Cancer & Oncology Authors: Jennifer G McIntosh Mark A Jenkins Anna Wood Patty Chondros Tina Campbell Edweana Wenkart Clare O'Reilly Ian Dixon Julie Toner Javiera Martinez Gutierrez Linda Govan Jon Emery Source Type: research

The gut microbiota in adults with cystic fibrosis compared to colorectal cancer
CONCLUSIONS: CF stool samples were clearly dysbiotic, clustering distinctly from both CRC and control samples. Several bacterial shifts in CF samples resembled those observed in CRC. Studies assessing the impact of dietary or other interventions and the longer-term use of CFTR modulators on reducing this potentially pro-oncogenic milieu are needed.PMID:38104000 | DOI:10.1016/j.jcf.2023.12.004 (Source: Cancer Control)
Source: Cancer Control - December 16, 2023 Category: Cancer & Oncology Authors: L R Caley H M Wood D Bottomley A Fuentes Balaguer L Wilkinson J Dyson C Young H White S Benton M Brearley P Quirke D G Peckham Source Type: research

Predicting risk of endometrial cancer in asymptomatic women (PRECISION): Model development and external validation
CONCLUSIONS: The Predicting risk of endometrial cancer in asymptomatic women model (PRECISION), using easily measurable anthropometric, reproductive, personal and family history, accurately quantifies a woman's 10-year risk of endometrial cancer. Its use could determine eligibility for primary endometrial cancer prevention trials and for targeted resource allocation in UK general practices.PMID:38073256 | DOI:10.1111/1471-0528.17729 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - December 11, 2023 Category: OBGYN Authors: Sarah J Kitson Emma J Crosbie D Gareth Evans Aritaya Lophatananon Kenneth R Muir Darren Ashcroft Evan Kontopantelis Glen P Martin Source Type: research

Cancers, Vol. 15, Pages 5754: Treat-to-Target and Regular Surveillance of Inflammatory Bowel Disease Are Associated with Low Incidence and Early-Stage Detection of Malignancies: A Retrospective Cohort Study
se Gionata Fiorino Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn&rsquo;s disease (CD), increase the risk of malignancies, particularly colorectal cancer (CRC). We aimed to assess the incidence of malignancies in IBD patients managed using a treat-to-target approach and recommended surveillance. We retrospectively searched the electronic databases of two tertiary IBD centers in Milan from 2010 to 2019 for new diagnoses of malignancy in patients with pre-existing IBD. A total of 5239 patients with a follow-up of 19,820 years were included. In total, 71 malignancies were diagnose...
Source: Cancers - December 8, 2023 Category: Cancer & Oncology Authors: Tommaso Lorenzo Parigi Mariangela Allocca Federica Furfaro Ferdinando D ’Amico Alessandra Zilli Arianna Dal Buono Roberto Gabbiadini Stefanos Bonovas Alessandro Armuzzi Silvio Danese Gionata Fiorino Tags: Article Source Type: research

Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment
ConclusionThe current literature suggests that androgens, estrogens, and progesterone are valuable in diagnosing and treating colorectal cancer, and that androgens promote the growth of colorectal cancer whereas estrogens and progesterone inhibit colorectal cancer, and that, in addition, the receptors associated with them are implicated in the modulation of a variety of cellular components of the microenvironment of colorectal cancer. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 5, 2023 Category: Cancer & Oncology Source Type: research

Genetic profile of Chinese patients with small bowel cancer categorized by anatomic location
Small bowel cancer (SBC) is a very rare solid malignancy. Consequently, compared with other malignant gastrointestinal tumors, our knowledge regarding SBC, specifically its molecular attributes, remains limite... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - November 16, 2023 Category: Genetics & Stem Cells Authors: Chengmin Shi, Junrui Ma, Tong Zhang, Yanqiang Shi, Weiming Duan, Depei Huang, Hushan Zhang and Yujian Zeng Tags: Research Source Type: research