Racial disparities of liver cancer mortality in Wisconsin
ConclusionsUsing ASF, we developed a high-resolution map of liver cancer mortality in Wisconsin. This map provided details on the distribution of liver cancer that were inaccessible in the county-level map. These tract-level estimates were associated with several racial and socioeconomic variables. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 17, 2019 Category: Cancer & Oncology Source Type: research

Post-operative colorectal cancer surveillance: preference for optical colonoscopy over computerized tomographic colonography
ConclusionsIn contrast to CRC screening, this first study in CRC post-operative surveillance patients demonstrates a preference for OC. Assuming patient preference is an important determinant, introduction of CTC as a method to increase patient adherence with CRC surveillance is unlikely to be effective.Trial registrationClinical Trials.gov registration number: NCT02143115. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 17, 2019 Category: Cancer & Oncology Source Type: research

Differences in reported sun protection practices, skin cancer knowledge, and perceived risk for skin cancer between rural and urban high school students
ConclusionsRural students reported less adequate use of sun protection than urban students. Rural male students reported lower knowledge scores compared to urban males. Future skin cancer prevention efforts targeting rural high schoolers are warranted. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 14, 2019 Category: Cancer & Oncology Source Type: research

Race/ethnicity and lung cancer survival in the United States: a meta-analysis
ConclusionsEven after adjustment for clinical factors and smoking status, Hispanics and Asians experienced improved survival compared to NHWs. Future studies are needed to elucidate the drivers of these survival disparities. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 14, 2019 Category: Cancer & Oncology Source Type: research

The impact of body size changes on recurrence risk depends on age and estrogen receptor status in primary breast cancer
AbstractPurposeTo investigate the prognostic impact of body size changes during the first postoperative year in breast cancer.MethodsA cohort of 1,317 primary breast cancer patients included in Sweden (2002 –2014) underwent body size measurements at the preoperative and 1-year visits (n = 1,178). Landmark survival analyses were used to investigate how postoperative weight gain or loss (>  5%) or change in waist–hip ratio (WHR) categories (≤ 0.85 or>  0.85) impact prognosis.ResultsMedian age at inclusion was 61  years and body mass index 25.1 kg/m2. After a med...
Source: Cancer Causes and Control - September 12, 2019 Category: Cancer & Oncology Source Type: research

A cohort study of personal and family history of skin cancer in relation to future risk of non-cutaneous malignancies
ConclusionsConsistent with prior reports, a personal history of skin cancer was associated with increase of developing internal malignancies, but this did not hold true for a family history of skin cancer. Further research is needed to understand why a personal history of skin cancer acts as a marker for increased risk for internal cancer. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 7, 2019 Category: Cancer & Oncology Source Type: research

World Cancer Research Fund International: Continuous Update Project —systematic literature review and meta-analysis of observational cohort studies on physical activity, sedentary behavior, adiposity, and weight change and breast cancer risk
ConclusionBetter understanding on the impact of these factors on pre- and postmenopausal breast cancers and their subtypes along the life course is needed. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 30, 2019 Category: Cancer & Oncology Source Type: research

Relationship between West African ancestry with lung cancer risk and survival in African Americans
ConclusionsGenetic ancestry is not a major contributor to lung cancer risk or survival disparities. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 29, 2019 Category: Cancer & Oncology Source Type: research

Correction to: Lung cancer screening: an emerging cancer control issue presents opportunities for an awareness campaign in rural Michigan
In the original publication of the article, the co-author name (Antoinette Percy-Laurry) was misspelled during the publication process. The coauthor name has been corrected in this correction. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 29, 2019 Category: Cancer & Oncology Source Type: research

Do breast quadrants explain racial disparities in breast cancer outcomes?
AbstractPurposeTumors of the inner quadrants of the breast are associated with poorer survival than those of the upper-outer quadrant. It is unknown whether racial differences in breast cancer outcomes are modified by breast quadrant, in addition to comparisons among Asian subgroups.MethodsUsing the Surveillance, Epidemiology, and End Results database, we analyzed data among women diagnosed with non-metastatic invasive breast cancer between 1990 and 2014. We performed Cox proportional hazards regression models to assess the associations of race with breast cancer-specific survival and overall survival, stratified by breast...
Source: Cancer Causes and Control - August 27, 2019 Category: Cancer & Oncology Source Type: research

Green tea consumption and risk of hematologic neoplasms: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
ConclusionsThe present cohort study suggests a protective effect of green tea against hematologic neoplasms, especially acute myeloid leukemias. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 26, 2019 Category: Cancer & Oncology Source Type: research

Inherited alterations of TGF beta signaling components in Appalachian cervical cancers
ConclusionsThis study reports novel associations between common low-penetrance alleles in the TGFB signaling cascade and modified risk of cervical cancer in Appalachian women. Furthermore, our unexpected findings associating Appalachian identity andNQO1 rs1800566 suggests that the complex environmental exposures that contribute to Appalachian self-identity in Appalachian cervical cancer patients represent an emerging avenue of scientific exploration. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 21, 2019 Category: Cancer & Oncology Source Type: research

Leveraging the strength of comprehensive cancer control coalitions to support policy, systems, and environmental change
AbstractStrategies that facilitate change to policy, systems, and environmental (PSE) changes can enable behaviors and practices that lead to cancer risk reduction, early detection, treatment access, and improved quality of life among survivors. Comprehensive cancer control is a coordinated collaborative approach to reduce cancer burden and operationalizes PSE change strategies for this purpose. Efforts to support these actions occur at the national, state, and local levels. Resources integral to bolstering strategies for sustainable cancer control include coordination and support from national organizations committed to a...
Source: Cancer Causes and Control - August 21, 2019 Category: Cancer & Oncology Source Type: research

Low serum cholesterol as a risk factor for kidney and bladder cancer among Korean men: using a national cohort sample
(Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 20, 2019 Category: Cancer & Oncology Source Type: research

Cancer incidence and associations with known risk and protective factors: the Alaska EARTH study
ConclusionsCancer incidence in the Alaska EARTH cohort was similar to incidence observed statewide. Risk and protective factors for leading cancers among AN people mirror those observed among other populations. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 19, 2019 Category: Cancer & Oncology Source Type: research

US urban –rural disparities in breast cancer-screening practices at the national, regional, and state level, 2012–2016
ConclusionsWhile urban –rural differences in breast cancer screening are small, they can translate into tens of thousands of rural women not receiving mammograms. Hence, there is a need to continue screening initiatives in these areas to reduce the number of breast cancer deaths. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 19, 2019 Category: Cancer & Oncology Source Type: research

Care experiences among dually enrolled older adults with cancer: SEER-CAHPS, 2005 –2013
ConclusionsDual enrollees with cancer reported better experiences than Medicare-only enrollees in terms of their health plan (Medicare FFS or Medicare Advantage) and their PDP. Better ratings among dually enrolled beneficiaries suggest possible divergence between health outcomes and care experiences, warranting additional investigation. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 17, 2019 Category: Cancer & Oncology Source Type: research

Type 2 diabetes and obesity in midlife and breast cancer risk in the Reykjavik cohort
ConclusionsThese findings in a population with low T2D incidence suggest that the presence of T2D does not confer additional breast cancer risk and confirm the importance of height and excess body weight as breast cancer risk factors. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 10, 2019 Category: Cancer & Oncology Source Type: research

Family history of cancer and the risk of childhood brain tumors: a pooled analysis of the ESCALE and ESTELLE studies (SFCE)
ConclusionOur findings support the hypothesis of a familial susceptibility of CBT, not due to being a known NF carrier. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 9, 2019 Category: Cancer & Oncology Source Type: research

Inflammation and breast density among female Chinese immigrants: exploring variations across neighborhoods
ConclusionsAmong Chinese immigrant women, aggregate analyses that do not take neighborhood context into consideration can mask potential variations in association of inflammatory markers with breast density. Future studies should consider how neighborhood contextual factors may contribute to differential risk pathways. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 7, 2019 Category: Cancer & Oncology Source Type: research

Improving the diagnostic accuracy of a stratified screening strategy by identifying the optimal risk cutoff
ConclusionOur research provides a general approach to optimize the diagnostic accuracy of a stratified screening strategy in a population, and to assess whether risk models are sufficiently accurate to guide stratified screening. For breast cancer, most risk models lack enough discriminatory accuracy to make stratified screening a reasonable recommendation. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 3, 2019 Category: Cancer & Oncology Source Type: research

Associations of mammographic breast density with breast stem cell marker-defined breast cancer subtypes
ConclusionsWe found no evidence of differential associations of breast density with breast cancer risk by the status of stem cell markers.  Further studies in larger study populations are warranted to confirm these associations. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 27, 2019 Category: Cancer & Oncology Source Type: research

Substitution of dietary protein sources in relation to colorectal cancer risk in the NIH-AARP cohort study
ConclusionsThis study shows that substituting plant protein for animal protein, especially red meat protein, is associated with a reduced risk of CRC, and suggests that protein source impacts CRC risk. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 20, 2019 Category: Cancer & Oncology Source Type: research

Influence of physical activity on active surveillance discontinuation in men with low-risk prostate cancer
ConclusionOur findings suggest that PA during AS for PCa does not significantly influence time to curative treatment. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 15, 2019 Category: Cancer & Oncology Source Type: research

Screening for anal cancer precursors among patients living with HIV in the absence of national guidelines: practitioners ’ perspectives
ConclusionsPractitioners who provide care for PLWH are proactive in screening to help prevent and control anal cancer, a rare and slow-growing disease. Continuing to regularly surveil high-risk populations, particularly PLWH previously diagnosed with high-grade lesions, is critical to prevent and control anal cancer. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 13, 2019 Category: Cancer & Oncology Source Type: research

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort
ConclusionsSurvival of sarcoma-SMN patients is worse than sarcoma-FMN patients. Although survival and tumor characteristics appear similar for breast-SMN and breast-FMN patients, treatment differs; breast-SMN patients less often receive breast-conserving therapy. Larger studies are necessary to substantiate these exploratory findings. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 12, 2019 Category: Cancer & Oncology Source Type: research

Cost-effectiveness of patient navigation for breast cancer screening in the National Breast and Cervical Cancer Early Detection Program
ConclusionsIncorporating PN services within the NBCCEDP may be a cost-effective way of improving adherence to screening and diagnostic resolution for women who have abnormal results from screening mammography. Our study highlights the value of supportive services such as PN in improving the quality of care offered within the NBCCEDP. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 11, 2019 Category: Cancer & Oncology Source Type: research

The association between colorectal sessile serrated adenomas/polyps and subsequent advanced colorectal neoplasia
ConclusionsOur results suggest that there is not a strong association between SSA/Ps and subsequent advanced colorectal neoplasia during the 5  years following SSA/P removal. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 9, 2019 Category: Cancer & Oncology Source Type: research

Systematic review on socioeconomic deprivation and survival in endometrial cancer
ConclusionsSocioeconomic deprivation seems to be associated with worse survival in endometrial cancer patients, even after adjusting for stage at diagnosis. However, the impacts of important confounders such as BMI, smoking and comorbidities are unclear and should be assessed. The relationship between socioeconomic deprivation and peri-operative morbidity is unclear, and further research is needed to evaluate this aspect. A standardised measure for socioeconomic deprivation is needed in order to establish adequate comparison between studies. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 8, 2019 Category: Cancer & Oncology Source Type: research

Patterns of comorbidities in women with breast cancer: a Canadian population-based study
ConclusionWomen with breast cancer had a higher risk of developing new comorbidities than women without cancer. Development of coordinated care models to manage multiple chronic diseases among breast cancer patients is warranted. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 6, 2019 Category: Cancer & Oncology Source Type: research

Circulating lipids, mammographic density, and risk of breast cancer in the Nurses ’ Health Study and Nurses’ Health Study II
ConclusionOverall, no association was observed between lipid levels and PMD, and there was no evidence that lipid levels modified the association between PMD and breast cancer risk. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - July 1, 2019 Category: Cancer & Oncology Source Type: research

Socioenvironmental adversity and risk of prostate cancer in non-Hispanic black and white men
AbstractNon-Hispanic black (NHB) men experience higher risk of prostate cancer than other racial/ethnic groups, and it is possible that socioenvironmental (SE) adversity and resulting stress may contribute to this disparity. Data from the Southern Community Cohort Study were used to evaluate associations between SE adversity and perceived stress in relation to prostate cancer risk, overall and by race/ethnicity and grade. Between 2002 and 2009, 26,741 men completed a questionnaire, from which an 8-item SE adversity composite was created (covering socioeconomic status, residential environment, and social support/buffers). T...
Source: Cancer Causes and Control - July 1, 2019 Category: Cancer & Oncology Source Type: research

Dose –risk relationships between cigarette smoking and ovarian cancer histotypes: a comprehensive meta-analysis
ConclusionsThis uniquely large and comprehensive meta-analysis confirms that although cigarette smoking does not appear to be a risk factor for ovarian cancer, and  it is even slightly protective for some rare histotypes, there is a strong dose–risk relationship with mucinous ovarian cancer. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 24, 2019 Category: Cancer & Oncology Source Type: research

Ovarian Cancer in Women of African Ancestry (OCWAA) consortium: a resource of harmonized data from eight epidemiologic studies of African American and white women
ConclusionOCWAA is uniquely positioned to study the epidemiology of EOC in AA women compared with white women to address disparities. Studies of EOC have been underpowered to address factors that may explain AA-white differences in the incidence and survival. OCWAA promises to provide novel insight into disparities in ovarian cancer. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 24, 2019 Category: Cancer & Oncology Source Type: research

Trajectories of body mass index, from adolescence to older adulthood, and pancreatic cancer risk; a population-based case –control study in Ontario, Canada
ConclusionBMI trajectories characterized by overweight in early adulthood were associated with increased pancreatic cancer risk suggesting a life-course approach to disease risk. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 22, 2019 Category: Cancer & Oncology Source Type: research

The association of marital status and mortality among men with early-stage prostate cancer treated with radical prostatectomy: insight into post-prostatectomy survival strategies
ConclusionsUnmarried men with prostate cancer were at greater risk for death after radical prostatectomy. Among married men with prostate cancer, marriage likely serves as a multi-faceted proxy for many protective factors including social support. Future studies should explore the mechanisms underlying these findings to inform the development of novel prostate cancer survival interventions for unmarried men and those with low social support. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 18, 2019 Category: Cancer & Oncology Source Type: research

Anticoagulants and cancer mortality in the Finnish randomized study of screening for prostate cancer
ConclusionOur study does not support reduced cancer mortality among anticoagulant users. Future studies on drug use and cancer mortality should be adjusted for anticoagulants as they are associated with significantly higher risk of cancer death. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 17, 2019 Category: Cancer & Oncology Source Type: research

The effect of delivery structure on costs, screening and health promotional services in state level National Breast and Cervical Cancer Early Detection Programs
ConclusionsMixed program structures were associated with the lowest screening and diagnostic costs per woman served and had generally favorable incremental costs relative to the other program structures. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 11, 2019 Category: Cancer & Oncology Source Type: research

Healthy dietary patterns and risk and survival of breast cancer: a meta-analysis of cohort studies
ConclusionsThe results suggested that healthy dietary patterns might be associated with a reduced risk of breast cancer and all-cause mortality among breast cancer patients. It could be clinically relevant to promote healthy dietary patterns for breast cancer prevention and improve survival among breast cancer patients. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 5, 2019 Category: Cancer & Oncology Source Type: research

Blood transfusion history and risk of non-Hodgkin lymphoma: an InterLymph pooled analysis
ConclusionsIn the setting of a literature reporting mainly null and some positive associations, and the lack of a clear methodologic explanation for our inverse association restricted to NHW men, the current body of evidence suggests that there is no association of blood transfusion with risk of NHL. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 4, 2019 Category: Cancer & Oncology Source Type: research

Association between greater leg length and increased incidence of colorectal cancer: the atherosclerosis risk in communities (ARIC) study
ConclusionsA positive association of leg length with CRC and colon cancer risk suggests that biological mechanisms leading to greater leg length during puberty may explain the association between taller height and CRC. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 4, 2019 Category: Cancer & Oncology Source Type: research

Soy and tea intake on cervical cancer risk: the Singapore Chinese Health Study
ConclusionsThese findings suggest that a protective effect of soy against cervical cancer development may depend on green tea constituents. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 1, 2019 Category: Cancer & Oncology Source Type: research

The association between coffee consumption and bladder cancer in the bladder cancer epidemiology and nutritional determinants (BLEND) international pooled study
ConclusionThis research suggests that positive associations between coffee consumption and BC among never smokers but not smokers. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 30, 2019 Category: Cancer & Oncology Source Type: research

The sensitivity of reported effects of EMF on childhood leukemia to uncontrolled confounding by residential mobility: a hybrid simulation study and an empirical analysis using CAPS data
ConclusionsWe conclude that uncontrolled confounding by residential mobility had some impact on the estimated effect of EMF exposures on childhood leukemia, but that it was unlikely to be the primary explanation behind previously observed largely consistent, but unexplained associations. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 29, 2019 Category: Cancer & Oncology Source Type: research

Development and validation of a model to predict outcomes of colon cancer surveillance
ConclusionThe model performed well in predicting curative surgery for three of four FACS arms. It performed well in predicting OS5 for all arms. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 25, 2019 Category: Cancer & Oncology Source Type: research

Awareness and interest in lung cancer screening among current and former smokers: findings from the ITC United States Survey
ConclusionsAwareness of LDCT lung cancer screening was lower among current smokers compared to former smokers. Most smokers who had not ever been screened said they would have lung cancer screening if it were recommended by their physician, demonstrating the need for healthcare providers to encourage those eligible for screening to take the test. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 23, 2019 Category: Cancer & Oncology Source Type: research

Treatment trends in head and neck cancer: Surveillance, Epidemiology, and End Results (SEER) Patterns of Care analysis
ConclusionsTreatment patterns have changed for HNC, leading to increased incorporation of systemic therapy and newer radiation techniques. HPV testing should be targeted for more widespread use, especially in traditionally underserved groups. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 22, 2019 Category: Cancer & Oncology Source Type: research

Awardee-specific economic costs of providing cancer screening and health promotional services to medically underserved women eligible in the National Breast and Cervical Cancer Early Detection Program
ConclusionsThe cost per woman served varied across awardee and likely reflected underlying differences across awardees in terms of screening infrastructure, population served, and barriers to screening uptake. Collecting information on contextual factors at the awardee, health system, provider, and individual levels may assist in understanding this variation in cost. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 20, 2019 Category: Cancer & Oncology Source Type: research

Disadvantaged neighborhoods and racial disparity in breast cancer outcomes: the biological link
AbstractNeighborhoods encompass complex environments comprised of unique economic, physical, and social characteristics that have a profound impact on the residing individual ’s health and, collectively, on the community’s wellbeing. Neighborhood disadvantage (ND) is one of several factors that prominently contributes to racial breast cancer (BC) health disparities in American women. African American (AA) women develop more aggressive breast cancer features, such as triple-negative receptor status and more advanced histologic grade and tumor stage, and suffer worse clinical outcomes than European American (EA) ...
Source: Cancer Causes and Control - May 20, 2019 Category: Cancer & Oncology Source Type: research

Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D 3 levels and survival among patients with metastatic colorectal cancer
ConclusionGermline genetic variation in the vitamin D pathway informs baseline 25(OH)D levels among patients with mCRC. The association between 25(OH)D levels and overall survival may vary byDHCR7 genotype.ClinicalTrials.gov Identifier: NCT00003594 (https://clinicaltrials.gov/ct2/show/NCT00003594). (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - May 18, 2019 Category: Cancer & Oncology Source Type: research