Evaluation of serum CA125, HE4 and CA724 and the risk of ovarian malignancy algorithm score in the diagnosis of high-grade serous ovarian cancer
CONCLUSION: The new algorithm using CA125 and BRCA1/2 helped to distinguish between patients with HGSOC and patients with non-HGSOC.PMID:38663180 | DOI:10.1016/j.ejogrb.2024.04.022 (Source: Reproductive Biology)
Source: Reproductive Biology - April 25, 2024 Category: Reproduction Medicine Authors: Deyu Hu Jun Qian Fenghua Yin Bing Wei Jiayu Wang Huijuan Zhang Haiou Yang Source Type: research
Ultrasound and cytopathological characteristics of thyroid tumours of uncertain malignant potential - from diagnosis to treatment
CONCLUSIONS: The study indicates that lesions with uncertain malignant potential typically present features suggesting low to intermediate risk of malignancy based on EU-TIRADS-PL classification, with dominant cytopathologic Bethesda IV category. However, 20% of lesions were assessed tas EU-TIRADS-PL category 5. Low-risk tumours, including NIFTP, FT-UMP, and WDT-UMP, require careful observation and monitoring post surgical treatment due to their potential for recurrence and metastasis. The preoperatively prediction of borderline tumour may play an important role in proper treatment and follow-up.PMID:38646986 | DOI:10.5603...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Agnieszka Żyłka Katarzyna Dobruch-Sobczak Hanna Piotrzkowska-Wr óblewska Maciej J ędrzejczyk Piotr G óralski Jacek Ga łczyński Elwira Baku ła-Zalewska Marek Dedecjus Source Type: research
Ultrasound and cytopathological characteristics of thyroid tumours of uncertain malignant potential - from diagnosis to treatment
CONCLUSIONS: The study indicates that lesions with uncertain malignant potential typically present features suggesting low to intermediate risk of malignancy based on EU-TIRADS-PL classification, with dominant cytopathologic Bethesda IV category. However, 20% of lesions were assessed tas EU-TIRADS-PL category 5. Low-risk tumours, including NIFTP, FT-UMP, and WDT-UMP, require careful observation and monitoring post surgical treatment due to their potential for recurrence and metastasis. The preoperatively prediction of borderline tumour may play an important role in proper treatment and follow-up.PMID:38646986 | DOI:10.5603...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Agnieszka Żyłka Katarzyna Dobruch-Sobczak Hanna Piotrzkowska-Wr óblewska Maciej J ędrzejczyk Piotr G óralski Jacek Ga łczyński Elwira Baku ła-Zalewska Marek Dedecjus Source Type: research
Inter-reader agreement of pancreatic adenocarcinoma resectability assessment with photon counting versus energy integrating detector CT
ConclusionThere was substantial inter-reader agreement for involvement of 4/5 major peripancreatic vessels (celiac artery, SMA, CHA, and SMV) at PCCT compared with 2/5 for EID-CT. PCCT also afforded substantial inter-reader agreement for metastasis detection versus moderate agreement at EID-CT with statistically significant radiation dose reduction.Grpahical abstract (Source: Abdominal Imaging)
Source: Abdominal Imaging - April 17, 2024 Category: Radiology Source Type: research
Reproductive outcomes in women opting for fertility preservation after fertility-sparing surgery for borderline ovarian tumors
ConclusionWomen who had FSS for BOT have favorable prospects of live offspring, even without the need to use their cryopreserved material. Fertility preservation in patients with BOT has to be considered as a tool to mitigate the risk of infertility that may arise in case of BOT recurrence requiring castrating surgery. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 16, 2024 Category: OBGYN Source Type: research
I saw the “sea anemone” sign: Puffy face of borderline ovarian tumors
The sea anemone sign is a radiologic sign seen on magnetic resonance imaging (MRI) studies that indicates the morphological development of serous borderline ovarian tumors (SBOTs), as papillary projections originating from the wall of the cystic lesion. The presence of T2 hypointense fibrous stroma in the center of the papilla is a helpful tip in the diagnosis of SBOTs. Those projections might also be assumed to have a frond-like appearance which can be seen as branching papillary projections, especially on T2-weighted imaging. (Source: Clinical Imaging)
Source: Clinical Imaging - April 16, 2024 Category: Radiology Authors: Yesim Yekta Yuruk, Hilal Şahin Tags: Body Imaging Source Type: research
Serum Levels of Intercellular Adhesion Molecule 1 and Vascular Cell Adhesion Molecule 1 as Biomarkers to Predict Radiotherapy Sensitivity in Cervical Cancer
CONCLUSION: Serum ICAM-1 and VCAM-1 levels show potential as predictive biomarkers for radiotherapy sensitivity in cervical cancer.PMID:38618575 | PMC:PMC11006555 | DOI:10.1055/a-2275-0717 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - April 15, 2024 Category: OBGYN Authors: Lina Song Yali Gao Zhicong Wang Yufeng Shi Source Type: research
Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer
ConclusionsThese data suggest that the presence of metastatic PDAC can be identified by integrating molecular compositions and drug responses of borderline resectable PDAC. (Source: Cellular Oncology)
Source: Cellular Oncology - April 15, 2024 Category: Cancer & Oncology Source Type: research
Ultrasound-based deep learning radiomics model for differentiating benign, borderline, and malignant ovarian tumours: a multi-class classification exploratory study
Accurate preoperative identification of ovarian tumour subtypes is imperative for patients as it enables physicians to custom-tailor precise and individualized management strategies. So, we have developed an u... (Source: BMC Medical Imaging)
Source: BMC Medical Imaging - April 15, 2024 Category: Radiology Authors: Yangchun Du, Wenwen Guo, Yanju Xiao, Haining Chen, Jinxiu Yao and Ji Wu Tags: Research Source Type: research
Hepatic arterial infusion pump chemotherapy combined with systemic chemotherapy for borderline resectable and unresectable colorectal liver metastases: phase II feasibility study
CONCLUSION: HAIP-SYS for borderline resectable and unresectable CRLMs was feasible and safe in the Netherlands. This has led to a successive multicentre phase III randomized trial investigating oncological benefit (EUDRA-CT 2023-506194-35-00). Current trial registration number: clinicaltrials.gov (NCT04552093).PMID:38608150 | DOI:10.1093/bjs/znae089 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - April 12, 2024 Category: Surgery Authors: Myrtle F Krul Niels F M Kok Harun Osmani Florian E Buisman Bas Groot Koerkamp Dirk J Grunhagen Cornelis Verhoef Bianca Mostert Petur Snaebjornsson Bram Westerink Elisabeth G Klompenhouwer Maarten L Donswijk Theo J M Ruers Joeri A J Douma Nico van Blijderv Source Type: research
