Post-surgical Intrauterine Adhesions After Hysteroscopic Myomectomy Using the Myoma Pseudocapsule Preservation Technique Evaluated bv Second-look Hysteroscopy: A Retrospective Comparative Study
To analyze the frequency and risk factors of post-surgical intrauterine adhesions (IUA) using second-look hysteroscopy (SLH) in patients undergoing hysteroscopic myomectomy carried out by the myoma pseudocapsule preservation technique for submucosal myoma. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - May 11, 2022 Category: OBGYN Authors: Yuko Ikemoto, Saki Nagai, Kaoru Tejima, Juichiro Saito Tags: Original Article Source Type: research

Postsurgical Intrauterine Adhesions after Hysteroscopic Myomectomy Using the Myoma Pseudocapsule Preservation Technique Evaluated bv Second-look Hysteroscopy: A Retrospective Comparative Study
To analyze the frequency and risk factors of postsurgical intrauterine adhesions (IUAs) using second-look hysteroscopy (SLH) in patients undergoing hysteroscopic myomectomy performed using the myoma pseudocapsule preservation technique for submucosal myoma. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - May 11, 2022 Category: OBGYN Authors: Yuko Ikemoto, Saki Nagai, Kaoru Tejima, Juichiro Saito Tags: Original Article Source Type: research

Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells
CONCLUSIONS: Conditionally reprogrammed physiological endometrial epithelial cells provide a novel strategy in IUA clinics in a personalized or generalized manner and also serve as a physiological model to explore biology of endometrial epithelial cells and mechanisms of IUA.PMID:35505443 | DOI:10.1186/s13287-022-02860-w (Source: Cell Research)
Source: Cell Research - May 3, 2022 Category: Cytology Authors: Siyu Xia Ming Wu Xinhao Zhou Xiu Zhang Lina Ye Kang Zhang Yiyi Kang Jun Liu Yunci Zhang Wang Wu Dirong Dong Hong Chen Hui Li Source Type: research

A Novel Nomogram Based on Three-dimensional Transvaginal Ultrasound for Differential Diagnosis Between Severe and Mild-to-moderate Intrauterine Adhesions
: To develop and validate a nomogram for differentiating severe intrauterine adhesions (IUAs) from mild-to-moderate IUAs preoperatively based on three-dimensional transvaginal ultrasound (3D-TVUS). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - April 10, 2022 Category: OBGYN Authors: Lei Lei, Lingxiao Zou, Yang Yu, Waixing Li, Aiqian Zhang, Dabao Xu Source Type: research

A Novel Nomogram Based on 3-dimensional Transvaginal Ultrasound for Differential Diagnosis Between Severe and Mild-to-Moderate Intrauterine Adhesions
To develop and validate a nomogram for differentiating severe intrauterine adhesions (IUAs) from mild-to-moderate IUAs preoperatively on the basis of 3-dimensional transvaginal ultrasound (3D-TVUS). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - April 10, 2022 Category: OBGYN Authors: Lei Lei, Lingxiao Zou, Yang Yu, Waixing Li, Aiqian Zhang, Dabao Xu Tags: Original Article Source Type: research

Pregnancy Patterns Impact Live Birth Rate for Patients With Intrauterine Adhesions After Hysteroscopic Adhesiolysis: A Retrospective Cohort Study
ConclusionsPregnancy patterns, age, number of visible tubal ostia, and AFS scores were significantly related to the live birth rate and may be considered potential predictors of the live birth rate in IUA patients. The indications of assisted reproductive technology (ART) might be a better choice for patients with recurrent IUAs. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 11, 2022 Category: Physiology Source Type: research

Local renin-angiotensin system molecular mechanisms in intrauterine adhesions formation following gynecological operations, new strategy for novel treatment
J Obstet Gynaecol. 2022 Mar 9:1-7. doi: 10.1080/01443615.2022.2036972. Online ahead of print.ABSTRACTIt has recently been proposed that local tissue renin-angiotensin system activation has a role in post-surgical adhesion. Intrauterine adhesions are scar tissues that form in the endometrial cavity causing the walls of the uterine to adhere together. Women, undergoing major gynecological surgery, are exposed to a high risk of adhesion formation. Post-operative uterine adhesion is associated with chronic pain and infertility that are important problems following post-operation uterine adhesion. A local renin-angiotensin syst...
Source: Journal of Obstetrics and Gynaecology - March 9, 2022 Category: OBGYN Authors: Sheida Shabanian Majid Khazaie Gordon A Ferns Mohammad-Hassan Arjmand Source Type: research

Prenatal diagnosis of placenta accreta spectrum
Purpose of review Placenta accreta spectrum (PAS) is a major cause of severe maternal morbidity. Perinatal outcomes are significantly improved when PAS is diagnosed prenatally. However, a large proportion of cases of PAS remain undiagnosed until delivery. Recent findings The prenatal diagnosis of PAS requires a high index of suspicion. The first step is identifying maternal risk factors. The most significant risk factor for PAS is the combination of a prior caesarean delivery and a placenta previa. Other major risk factors include a prior history of PAS, caesarean scar pregnancy (CSP), uterine artery embolizatio...
Source: Current Opinion in Obstetrics and Gynecology - March 2, 2022 Category: OBGYN Tags: PRENATAL DIAGNOSIS: Edited by Jane Chueh Source Type: research

Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions
Autophagy. 2022 Feb 23:1-16. doi: 10.1080/15548627.2022.2038994. Online ahead of print.ABSTRACTIntrauterine adhesions (IUA), characterized by endometrial fibrosis, is a common cause of uterine infertility. We previously demonstrated that partial epithelial-mesenchymal transition (EMT) and the loss of epithelial homeostasis play a vital role in the development of endometrial fibrosis. As a pro-survival strategy in maintaining cell and tissue homeostasis, macroautophagy/autophagy, conversely, may participate in this process. However, the role of autophagy in endometrial fibrosis remains unknown. Here, we demonstrated that au...
Source: Autophagy - February 23, 2022 Category: Cytology Authors: Zhenhua Zhou Huiyan Wang Xiwen Zhang Minmin Song Simin Yao Peipei Jiang Dan Liu Zhiyin Wang Haining Lv Ruotian Li Ying Hong Jianwu Dai Yali Hu Guangfeng Zhao Source Type: research

Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions
Autophagy. 2022 Feb 23:1-16. doi: 10.1080/15548627.2022.2038994. Online ahead of print.ABSTRACTIntrauterine adhesions (IUA), characterized by endometrial fibrosis, is a common cause of uterine infertility. We previously demonstrated that partial epithelial-mesenchymal transition (EMT) and the loss of epithelial homeostasis play a vital role in the development of endometrial fibrosis. As a pro-survival strategy in maintaining cell and tissue homeostasis, macroautophagy/autophagy, conversely, may participate in this process. However, the role of autophagy in endometrial fibrosis remains unknown. Here, we demonstrated that au...
Source: Autophagy - February 23, 2022 Category: Cytology Authors: Zhenhua Zhou Huiyan Wang Xiwen Zhang Minmin Song Simin Yao Peipei Jiang Dan Liu Zhiyin Wang Haining Lv Ruotian Li Ying Hong Jianwu Dai Yali Hu Guangfeng Zhao Source Type: research

Effect of hysteroscopic adhesiolysis on recurrence, menstruation and pregnancy outcomes in patients with different degrees of intrauterine adhesions
CONCLUSION: The treatment effect and prognosis of patients were related to the degree of intrauterine adhesions before treatment. As the degree of intrauterine adhesions increased, the treatment effect and prognosis of patients became worse, and intensive treatment was needed. (Chinese Clinical Trial Registry, trial number ChiCTR1700026770, trial URL: http://www.chictr.org.cn/).PMID:35173868 | PMC:PMC8829641 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - February 17, 2022 Category: Research Authors: Lu Wang Chen Guo Huabin Cao Source Type: research