Management of intrauterine adhesions using human amniotic mesenchymal stromal cells to promote endometrial regeneration and repair through Notch signalling
J Cell Mol Med. 2021 Nov 1. doi: 10.1111/jcmm.17023. Online ahead of print.ABSTRACTIntrauterine adhesions (IUAs) severely hamper women's reproductive functions. Human amniotic mesenchymal stromal cell (hAMSC) transplantation is effective in treating IUAs. Here, we examined the function of Notch signalling in IUA treatment with hAMSC transplantation. Forty-five Sprague-Dawley female rats were randomly divided into the sham operation, IUA, IUA + E2, IUA + hAMSCs and IUA + hAMSCs + E2 groups. After IUA induction in the rats, hAMSCs promoted endometrial regeneration and repair via differentiation into endometrial epithelial ce...
Source: J Cell Mol Med - November 1, 2021 Category: Molecular Biology Authors: Jie Yu Wenwen Zhang Jiayue Huang Yating Gou Congcong Sun Yingfeng Zhang Yanhua Mao Benyuan Wu Changjiang Li Nizhou Liu Tingting Wang Jiren Huang Jia Wang Source Type: research
Management of intrauterine adhesions using human amniotic mesenchymal stromal cells to promote endometrial regeneration and repair through Notch signalling
J Cell Mol Med. 2021 Nov 1. doi: 10.1111/jcmm.17023. Online ahead of print.ABSTRACTIntrauterine adhesions (IUAs) severely hamper women's reproductive functions. Human amniotic mesenchymal stromal cell (hAMSC) transplantation is effective in treating IUAs. Here, we examined the function of Notch signalling in IUA treatment with hAMSC transplantation. Forty-five Sprague-Dawley female rats were randomly divided into the sham operation, IUA, IUA + E2, IUA + hAMSCs and IUA + hAMSCs + E2 groups. After IUA induction in the rats, hAMSCs promoted endometrial regeneration and repair via differentiation into endometrial epithelial ce...
Source: Molecular Medicine - November 1, 2021 Category: Molecular Biology Authors: Jie Yu Wenwen Zhang Jiayue Huang Yating Gou Congcong Sun Yingfeng Zhang Yanhua Mao Benyuan Wu Changjiang Li Nizhou Liu Tingting Wang Jiren Huang Jia Wang Source Type: research
Hysteroscopic findings after laparoscopic and open myomectomy with or without uterine cavity breach: historical cohort study
CONCLUSIONS: According to our findings, the prevalence of post-myomectomy intrauterine adhesions after myomectomy is low. Our study did not demonstrate that UCB during myomectomy is a risk factor for the formation of intrauterine synechiae.PMID:34669526 | DOI:10.1080/13645706.2021.1986542 (Source: Minimally Invasive Therapy and Allied Technologies)
Source: Minimally Invasive Therapy and Allied Technologies - October 20, 2021 Category: Surgery Authors: Barbora Boudova Kristyna Hlinecka Zdenka Lisa Adela Richtarova Zdenek Zizka Michal Mara Source Type: research
Bio-modulated mice epithelial endometrial organoids by low-level laser therapy serves as an invitro model for endometrial regeneration
In conclusion, organoids whether control or bio-stimulated proved a new modality to regenerate the endometrium.PMID:34662815 | DOI:10.1016/j.repbio.2021.100564 (Source: Reproductive Biology)
Source: Reproductive Biology - October 18, 2021 Category: Reproduction Medicine Authors: Mona Gebril Amal Aboelmaaty Osama Al Balah Tamer Taha Amr Abbassy Mohamed Amr H Elnoury Source Type: research
Success of Serial Office Resection in Severe Asherman's Syndrome
Demonstrate the feasibility and effectiveness of serial office hysteroscopic lysis of adhesions for a severe case of Asherman's Syndrome. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: A. Zelivianskaia, L. Barrison, J.K. Robinson Tags: 6389 Source Type: research
Incidence and Clinical Implications of Placenta Accreta Spectrum (PAS) after Hysteroscopic Treatment for Asherman's Syndrome
To investigate the incidence of placenta accreta spectrum (PAS), predictors for malplacentation and clinical implications in pregnancies after hysteroscopic treatment for Asherman syndrome. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: J. Tavcar, P.R. Movilla, D.A. Carusi, M. Loring, H. Reddy, K.B. Isaacson, S.N. Morris Tags: 5794 Source Type: research
Hysteroscopy Assisted Suction Curettage for Early Miscarriage: Does It Reduce Rpocn and Postoperative Intrauterine Adhesions?
To describe the feasibility of hysteroscopy assisted suction curettage for early pregnancy loss and to investigate whether it reduces the rates of retained products of conception (RPOC) and intrauterine adhesions (IUA). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: O. Moore, T. Tzur, Z. Vaknin, M. Landau Rabbi, N. Smorgick Tags: 5677 Source Type: research
Safety & Efficacy of Womed Leaf ™, a Novel Barrier Film to Prevent Intrauterine Adhesions after Hysteroscopic Myomectomy: The PREG1 Trial.
The objective of this first-in-human study was to evaluate the safety of the novel intrauterine adhesion barrier film Womed LeafTM and pilot its potential efficacy in preventing IUAs after hysteroscopic myomectomy. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: S. Weyers, P. Capmas, S. Huberlant, J. Dijkstra, A.B. Hooker, T.W.O. Hamerlynck, E. Debras, R. De Tayrac, A.L. Thurkow, H. Fernandez Tags: Plenary 5: Fibroids Source Type: research
Combined Hysteroscopic and Laparoscopic Approach to a Complicated Case of Asherman's Syndrome
We aim to present a combined hysteroscopic and laparoscopic approach to the resection of a post-cesarean section scar causing complete obstruction of the endometrial cavity. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: A.R. Schmidt, D. Luciano, A.P Ulrich Tags: 6320 Source Type: research
Asherman's Syndrome (AS) after Long Term Use of a Levenorgestrel Containing IUD, Cause or Coincidence?
Identifying risk factors for developing Asherman's Syndrome after a first trimester procedure. Could the influence of long-term use of a levenorgestrel IUD (LNG-IUD) be a risk factor? (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: J.F. Molkenboer, M. Hanstede Tags: 5906 Source Type: research
Asherman's Care in a Covid-19 Pandemic
We aimed to evaluate patient's satisfaction with Asherman's care in women who were referred to our center for a second opinion for Asherman's Syndrome (AS) in the Covid-19 pandemic. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 16, 2021 Category: OBGYN Authors: M.M. Hanstede Tags: 5969 Source Type: research
The implementation of routine procedural transvaginal sonography to decrease retained products of conception: a quality improvement initiative
Retained products of conception (POC) following uterine evacuation can lead to adverse sequelae, including hemorrhage, endometritis, intrauterine adhesions, and reoperation. Use of procedural transvaginal sono... (Source: BMC Women's Health)
Source: BMC Women's Health - October 3, 2021 Category: OBGYN Authors: M. Alyssa Larish, E. Claire Jensen, C. Kristin Mara, C. Isabel Green, R. Matthew Hopkins, K. Shannon Laughlin-Tommaso, L. Tatnai Burnett and M. Daniel Breitkopf Tags: Research article Source Type: research
