An argument for quality improvement in Asherman syndrome counseling
The sequelae of Asherman syndrome or intrauterine adhesions (IUAs) to women of childbearing age include amenorrhea, hypomenorrhea, cyclic pelvic pain, infertility, recurrent pregnancy loss, and abnormal placentation [1]. Although the estimated incidence of IUAs vary, current data suggest an incidence of 15-30% after suction D&C and 8-22% after myomectomy[1]. These figures vary significantly based on whether a D&C is performed in early pregnancy or late pregnancy/postpartum, as well as the approach to myomectomy. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - January 12, 2023 Category: OBGYN Authors: James K. Robinson, Aparna Ramanathan, Rebecca Thompson Tags: EDITORIAL Source Type: research

Surgical approach to four different reproductive pathologies by three different gynecologic subspecialties: More similarities or differences?
In this case, pre-operative planning is the key component to all three groups ’ thought process where the MRI findings are suggestive of an atypical leiomyoma. MIGS and GYN-Onc both recommend an endometrial biopsy to evaluate for leiomyosarcoma. Despite this being a very large transmural fibroid involving the endometrial cavity with suspicious MRI findings, all specialties agree that a laparoscopic approach was appropriate, with MIGS and REI focusing on the inevitability of needing to repair the endometrial defect and avoiding intrauterine adhesions. (Source: Fertility and Sterility)
Source: Fertility and Sterility - December 24, 2022 Category: Reproduction Medicine Authors: John Petrozza, Victoria Fitz, Bala Bhagavath, Jose Carugno, Jaclyn Kwal, Emad Mikhail, Moawad Nash, Syem K. Barakzai, Dario R. Roque, Amy J. Bregar, Joseph Findley, Michael Neblett, Rebecca Flyckt, Zaraq Khan, Steven R. Lindheim Source Type: research

Characteristics and transcriptomic analysis of scar tissues on the inner uterine cavity wall in patients with intrauterine adhesions
In this study, myometrium with normal uterus were assigned to the control group and scar tissues with IUAs were assigned to the experimental group. And pathological characteristics and transcriptomic were analyzed between the two groups.Results: We founded no difference was noted in the histological morphology and the α-SMA expression between the experimental and control groups. A total of 698 differentially expressed genes were identified between the two groups. Gene Ontology (GO) analyses revealed that the DEGs were significantly enriched in cell proliferation, AP-1 complex formation, and angiogenesis. Kyoto Encyclopedi...
Source: Frontiers in Physiology - December 22, 2022 Category: Physiology Source Type: research

Cost-Savings Analysis of Routine Hysteroscopy for Early Detection and Treatment of Intrauterine Adhesions
Journal of Gynecologic Surgery, Ahead of Print. (Source: Journal of Gynecologic Surgery)
Source: Journal of Gynecologic Surgery - December 5, 2022 Category: OBGYN Authors: Anna Zelivianskaia Arthur Arcaz Paul Kolm James K. Robinson Nicholas Hazen Source Type: research

Clinical Effect of Intrauterine 3-Dimensional Ultrasound on the Function of the Intrauterine Cavity of Puerpera With Intrauterine Adhesions and Safety of Pregnancy
This study aimed to analyze the diagnostic value of intrauterine 3-dimensional ultrasound and the functional characteristics of the intrauterine cavity for puerpera with intrauterine adhesions, and to explore the safety of pregnancy after treatment. A total of 102 puerperas with intrauterine adhesions were randomly selected, and intrauterine 3-dimensional ultrasound and 2-dimensional ultrasound were performed, respectively. Patients were followed up for 3 years to observe the pregnancy outcome and safety. The overall accuracy of diagnosing intrauterine adhesions through intrauterine 3-dimensional ultrasound was significant...
Source: Ultrasound Quarterly - December 1, 2022 Category: Radiology Tags: Original Research Source Type: research

The link between intrauterine adhesions and impaired reproductive performance: a systematic review of the literature
Intrauterine adhesions (IUAs) are one of the main reproductive system diseases in women worldwide. Fusion between the injured opposing walls leads to partial-to-complete obliteration of the cavity and/or cervi... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - November 14, 2022 Category: OBGYN Authors: Angelo B. Hooker, Robert A. de Leeuw, Mark Hans Emanuel, Velja Mijatovic, Hans A. M. Brolmann and Judith A.F. Huirne Tags: Research Source Type: research