Human amniotic mesenchymal stem cells  promote endometrium regeneration in a rat model of intrauterine adhesion
This study aimed to investigate the mechanism by which hAMSCs transplantation promotes endometrial regeneration. The rat models with IUA were established through mechanical and infective methods, and PKH26-labeled hAMSCs were transplanted through the tail vein (combined with/without estrogen). Under three different conditions, hAMSCs differentiated into endometrium-like cells. HE and Mason staining assays, and immunohistochemistry were used to compare the changes in rat models treated with hAMSCs and/or estrogen transplantation. To define the induction of hAMSCs to endometrium-like cells in vitro, an induction medium (cyto...
Source: Cell Biology International - November 1, 2022 Category: Cytology Authors: Yanhua Mao Yuan Yang Congcong Sun Yulong Zou Yingfeng Zhang Benyuan Wu Changjiang Li Jinglin Huang Wenwen Zhang Jia Wang Source Type: research

Human amniotic mesenchymal stem cells  promote endometrium regeneration in a rat model of intrauterine adhesion
This study aimed to investigate the mechanism by which hAMSCs transplantation promotes endometrial regeneration. The rat models with IUA were established through mechanical and infective methods, and PKH26-labeled hAMSCs were transplanted through the tail vein (combined with/without estrogen). Under three different conditions, hAMSCs differentiated into endometrium-like cells. HE and Mason staining assays, and immunohistochemistry were used to compare the changes in rat models treated with hAMSCs and/or estrogen transplantation. To define the induction of hAMSCs to endometrium-like cells in vitro, an induction medium (cyto...
Source: Cell Biology International - November 1, 2022 Category: Cytology Authors: Yanhua Mao Yuan Yang Congcong Sun Yulong Zou Yingfeng Zhang Benyuan Wu Changjiang Li Jinglin Huang Wenwen Zhang Jia Wang Source Type: research

Intrauterine adhesions after manual/electric vacuum aspiration without sharp curettage
Manual vacuum aspiration (MVA) and electric vacuum aspiration (EVA) are options for surgical management of early pregnancy loss and undesired pregnancy, as well as diagnostic work-up for pregnancy of unknown location. Though rare, these procedures can be associated with the risk of intrauterine adhesions (IUAs). This is referred to as Asherman ’s syndrome when associated with symptoms such as infertility, menstrual abnormalities, or recurrent pregnancy loss.1 The true incidence of IUAs after MVA/EVA is not well established but is estimated to range from 2%-30%. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2022 Category: Reproduction Medicine Authors: Adriana J. Wong, Melissa C. Matulich, Juliana A. Melo Source Type: research

8999 Reproductive Outcomes and Overall Prognosis of Patients with Asherman's Syndrome Undergoing IVF Cycles
To estimate the impact of Asherman's Syndrome (AS) following hysteroscopic adhesiolysis on short term reproductive outcomes and the time to achieve pregnancy in infertile patients during IVF cycles. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - November 1, 2022 Category: OBGYN Authors: I. Levin, A. Cohen, F. Azem, A. Kidron, Z. Shapira, Y. Fouks Source Type: research

8466 Creating the Uterine Cavity in Global Asherman's Syndrome
Resumption of Menstruation in patients with Total amenorrhea with Global Asherman's Syndrome following Hysteroscopic surgery. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - November 1, 2022 Category: OBGYN Authors: K. Subramanian Source Type: research

8383 Removal of Intrauterine Adhesions Using an Ultrasound-Guided Balloon Therapy
To demonstrate a novel technique to treat intrauterine adhesions (IUAs) in an outpatient setting found at the time of saline infusion sonohysterography (SIS). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - November 1, 2022 Category: OBGYN Authors: J.L. Kahn, T. Niderberg, A. Bayer, S.E. Pollack, M. Singh Source Type: research

8148 Comparison of Surface Area Covered by Intrauterine Foley Catheter vs. T-Shaped Intrauterine Device Following Hysteroscopic Adhesiolysis
To visualize the surface area covered by a T-shaped IUD versus that of a pediatric-sized foley catheter following hysteroscopic adhesiolysis for Asherman's Syndrome. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - November 1, 2022 Category: OBGYN Authors: J. Okohue, H. Olalere, S.M. Wagner, J.A. Carugno Source Type: research

Study on Risk Factors Related to Intrauterine Adhesion Based on Meta-Analysis
CONCLUSION: Pelvic inflammatory disease, negative pressure during uterine suction and uterine suction time are the risk factors leading to uterine cavity adhesion.PMID:36267305 | PMC:PMC9578867 | DOI:10.1155/2022/4667679 (Source: Computational and Mathematical Methods in Medicine)
Source: Computational and Mathematical Methods in Medicine - October 21, 2022 Category: Statistics Authors: Sijing Li Source Type: research

Comparison of endometrial preparation protocols (natural cycle versus hormone replacement cycle) for frozen embryo transfer (COMPETE): a study protocol for a randomised controlled trial
This study has been approved by the Institutional Review Board of Northwest women’s and children’s hospital (2020008). Written informed consent will be obtained from each participant before randomisation. The results of the trial will be presented via publications. Trial registration number ChiCTR2000040640. (Source: BMJ Open)
Source: BMJ Open - October 14, 2022 Category: General Medicine Authors: Liu, X., Wen, W., Wang, T., Sun, T., Wang, T., Zhang, N., Pan, D., Cai, H., Xie, J., Liu, X., Shi, Z., Wang, R., Li, X., Lu, N., Pan, R., Tian, L., Meng, B., Bai, H., Zhou, H., Qu, P., Zhao, D., Mol, B. W., Li, W., Shi, J. Tags: Open access Obstetrics and gynaecology Source Type: research

To study the current status of uterine adhesions after fetal residue and the preventive effect of using estrogen and progesterone sequential therapy combined with Foley balloon
To investigate the current status of uterine adhesions in patients with residual fetus and analyze the preventive effect of estrogen and progesterone sequential therapy combined with Foley balloon. Eighty-six patients with residual fetus were divided into control group and observation group. On the basis of the treatment plan of the control group, the observation group received estrogen and progesterone sequential therapy combined with Floey balloon treatment. Clinical efficacy, postoperative recovery status (abdominal pain duration, vaginal bleeding duration, vaginal bleeding volume, refluid time), the incidence of intrau...
Source: Medicine - September 9, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A novel technique for moderate to severe intrauterine adhesions: A historical cohort study
To evaluate the feasibility and efficiency of our novel technique, ultrasound guided hysteroscopic catheter dilation (US-HCD), for the treatment of moderate to severe intrauterine adhesion (IUA). A total of 126 patients diagnosed with IUA and met the enrollment criteria were admitted in this historical cohort study from June 1, 2016 to December 31, 2018. All patients were divided into 2 groups according to the surgical techniques used. Group A (n = 68) were treated with traditional hysteroscopic adhesiolysis with scissors (THA) and Group B (n = 58) were treated with US-HCD. Their data for the next 2 years following...
Source: Medicine - September 9, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Estradiol and intrauterine device treatment for moderate and severe intrauterine adhesions after transcervical resection
To explore the effect of 4 mg/day, 6 mg/day, and 8 mg/day estradiol alone or in combination with an intrauterine device (IUD) in patients with moderate and severe intrauterine adhesion (IUA) after transcervica... (Source: BMC Women's Health)
Source: BMC Women's Health - August 29, 2022 Category: OBGYN Authors: Yun Sun, Xiuying Chen, Zhida Qian, Lili Cao, Sifeng Zhan and Lili Huang Tags: Research Source Type: research

Reproductive Outcomes and Overall Prognosis of Women with Asherman's Syndrome Undergoing IVF
To evaluate the impact of Asherman's Syndrome (AS) following hysteroscopic adhesiolysis on reproductive outcomes and the time to achieve pregnancy in infertile women undergoing in vitro fertilization (IVF) treatment. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - August 12, 2022 Category: OBGYN Authors: Yuval Fouks, Adi Kidron, Inbar Lavie, Ziv Shapira, Yoni Cohen, Ishai Levin, Foad Azem MD, Aviad Cohen Tags: ORIGINAL ARTICLE Source Type: research