Post-dissection Thoraco-abdominal Aortic Aneurysm Managed with Fenestrated or Branched Endovascular Aortic Repair
This study aimed to analyse early and follow up outcomes of f/bEVAR. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - April 30, 2024 Category: Surgery Authors: Filippo Gorgatti, Petroula Nana, Giuseppe Panuccio, Fiona Rohlffs, Jos é I. Torrealba, Tilo Kölbel Source Type: research
Research trends and hotspots of circular RNA in cardiovascular disease: A bibliometric analysis
Noncoding RNA Res. 2024 Apr 16;9(3):930-944. doi: 10.1016/j.ncrna.2024.04.002. eCollection 2024 Sep.ABSTRACTFrom a global perspective, cardiovascular diseases (CVDs), the leading factor accounting for population mortality, and circRNAs, RNA molecules with stable closed-loop structures, have been proven to be closely related. The latent clinical value and the potential role of circRNAs in CVDs have been attracting increasing, active research interest, but bibliometric studies in this field are still lacking. Thus, in this study, we conducted a bibliometric analysis by using software such as VOSviewer, CiteSpace, Microsoft E...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Zehui Xu Chong Guan Ziji Cheng Houle Zhou Wanting Qin Jiaming Feng Melisandre Wan Yihan Zhang Chengyao Jia Shuijin Shao Haidong Guo Shaoling Li Baonian Liu Source Type: research
Impact of Non-Diameter Aortic Indices on Surgical Eligibility: Results from the TITAN: SvS Randomized Controlled Trial
The objective of this study was to evaluate the impact of using these newer indices on patient eligi bility for surgical intervention in a prospective, multicenter cohort with moderate sized ascending aortic aneurysms between 5.0-5.4 cm. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 29, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Olina Dagher, Jehangir J. Appoo, Eric Herget, Rony Atoui, Cristian Baeza, William Brinkman, John Bozinovski, Michael W.A. Chu, Francois Dagenais, Philippe Demers, Nimesh Desai, Ismail El-Hamamsy, Anthony Estrera, Juan B. Grau, G. Chad Hughes, Arminder Jas Source Type: research
A Core Outcome Set for Intact Abdominal Aortic Aneurysm Repair
CONCLUSION: Six core outcomes are recommended for use as a minimum framework in all future studies and registries of intact open and endovascular AAA repair. Further work to select instruments for quality of life and define instruments for cognitive functioning is needed.PMID:38677466 | DOI:10.1016/j.ejvs.2024.04.029 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - April 27, 2024 Category: Surgery Authors: Matthew Machin Anders Wanhainen Mario D'Oria Mark Koelemaij Stavros Kakkos Matthew Joe Grima Janet T Powell collaborators Source Type: research
A Core Outcome Set for Intact Abdominal Aortic Aneurysm Repair
CONCLUSION: Six core outcomes are recommended for use as a minimum framework in all future studies and registries of intact open and endovascular AAA repair. Further work to select instruments for quality of life and define instruments for cognitive functioning is needed.PMID:38677466 | DOI:10.1016/j.ejvs.2024.04.029 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - April 27, 2024 Category: Surgery Authors: Matthew Machin Anders Wanhainen Mario D'Oria Mark Koelemaij Stavros Kakkos Matthew Joe Grima Janet T Powell collaborators Source Type: research
Unravelling the role of cathepsins in cardiovascular diseases
Mol Biol Rep. 2024 Apr 26;51(1):579. doi: 10.1007/s11033-024-09518-1.ABSTRACTLysosomal cathepsins as a regulatory medium have been assessed as potential therapeutic targets for the treatment of various cardiac diseases such as abdominal aortic aneurysm, hypertension, cardiomyopathy, coronary heart disease, atherosclerosis, etc. They are ubiquitous lysosomal proteases with papain-like folded protein structures that are involved in a variety of physiological processes, such as the digestion of proteins, activation of pro-inflammatory molecules, degradation of extracellular matrix components, and maturation of peptide hormone...
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Sonali Maheshwari Bhoomika M Patel Source Type: research
Unravelling the role of cathepsins in cardiovascular diseases
Mol Biol Rep. 2024 Apr 26;51(1):579. doi: 10.1007/s11033-024-09518-1.ABSTRACTLysosomal cathepsins as a regulatory medium have been assessed as potential therapeutic targets for the treatment of various cardiac diseases such as abdominal aortic aneurysm, hypertension, cardiomyopathy, coronary heart disease, atherosclerosis, etc. They are ubiquitous lysosomal proteases with papain-like folded protein structures that are involved in a variety of physiological processes, such as the digestion of proteins, activation of pro-inflammatory molecules, degradation of extracellular matrix components, and maturation of peptide hormone...
Source: Molecular Biology Reports - April 26, 2024 Category: Molecular Biology Authors: Sonali Maheshwari Bhoomika M Patel Source Type: research
Unravelling the role of cathepsins in cardiovascular diseases
Mol Biol Rep. 2024 Apr 26;51(1):579. doi: 10.1007/s11033-024-09518-1.ABSTRACTLysosomal cathepsins as a regulatory medium have been assessed as potential therapeutic targets for the treatment of various cardiac diseases such as abdominal aortic aneurysm, hypertension, cardiomyopathy, coronary heart disease, atherosclerosis, etc. They are ubiquitous lysosomal proteases with papain-like folded protein structures that are involved in a variety of physiological processes, such as the digestion of proteins, activation of pro-inflammatory molecules, degradation of extracellular matrix components, and maturation of peptide hormone...
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Sonali Maheshwari Bhoomika M Patel Source Type: research
Unravelling the role of cathepsins in cardiovascular diseases
Mol Biol Rep. 2024 Apr 26;51(1):579. doi: 10.1007/s11033-024-09518-1.ABSTRACTLysosomal cathepsins as a regulatory medium have been assessed as potential therapeutic targets for the treatment of various cardiac diseases such as abdominal aortic aneurysm, hypertension, cardiomyopathy, coronary heart disease, atherosclerosis, etc. They are ubiquitous lysosomal proteases with papain-like folded protein structures that are involved in a variety of physiological processes, such as the digestion of proteins, activation of pro-inflammatory molecules, degradation of extracellular matrix components, and maturation of peptide hormone...
Source: Molecular Biology Reports - April 26, 2024 Category: Molecular Biology Authors: Sonali Maheshwari Bhoomika M Patel Source Type: research
Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set
CONCLUSION: The fatty acid metabolism pathway appears to be linked to the development of both AS and AAA. Furthermore, PCBD1, ACADL, MGLL, BCKDHB, and IDH3G have the potential to serve as diagnostic markers for patients with AS complicated by AAA.PMID:38660376 | PMC:PMC11040089 | DOI:10.3389/fmolb.2024.1365447 (Source: Atherosclerosis)
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Xuefeng Gu Zhongxian Yu Tianwei Qian Yiqi Jin Guoxiong Xu Jiang Li Jianfeng Gu Ming Li Ke Tao Source Type: research
Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set
CONCLUSION: The fatty acid metabolism pathway appears to be linked to the development of both AS and AAA. Furthermore, PCBD1, ACADL, MGLL, BCKDHB, and IDH3G have the potential to serve as diagnostic markers for patients with AS complicated by AAA.PMID:38660376 | PMC:PMC11040089 | DOI:10.3389/fmolb.2024.1365447 (Source: Atherosclerosis)
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Xuefeng Gu Zhongxian Yu Tianwei Qian Yiqi Jin Guoxiong Xu Jiang Li Jianfeng Gu Ming Li Ke Tao Source Type: research
A Core Outcome Set for Intact Abdominal Aortic Aneurysm Repair
This study aimed to develop an international core outcome set for intact AAA repair. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - April 25, 2024 Category: Surgery Authors: Matthew Machin, Anders Wanhainen, Mario D'Oria, Mark Koelemaij, Stavros Kakkos, Matthew Joe Grima, Janet T. Powell, collaborators Source Type: research
Postoperative serum mir-28-5p level has predictive value for the prognosis after endovascular abdominal aortic aneurysm repair
We explored the clinical significance of miR-28-5p pre- and post-endovascular abdominal aortic aneurysm repair (EVAR) in abdominal aortic aneurysm (AAA) patients. (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 25, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Senyan Wu, Guobing Cheng, Wei Lu and Youyao Xu Tags: Research Source Type: research
Hemarthrosis in a patient with abdominal aortic aneurysm
To the Editor: (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Hiroyuki Tsurumi, Hiroyuki Yano, Mitsuyo Kinjo Tags: Clinical Communication to the Editor Source Type: research
Unravelling CD4 < sup > + < /sup > T cell diversity and tissue adaptation of Tregs in abdominal aortic aneurysms through single-cell sequencing
Immunology. 2024 Apr 18. doi: 10.1111/imm.13796. Online ahead of print.ABSTRACTImmune cell infiltration is a significant pathological process in abdominal aortic aneurysms (AAA). T cells, particularly CD4+ T cells, are essential immune cells responsible for substantial infiltration of the aorta. Regulatory T cells (Tregs) in AAA have been identified as tissue-specific; however, the time, location, and mechanism of acquiring the tissue-specific phenotype are still unknown. Using single-cell RNA sequencing (scRNA-seq) on CD4+ T cells from the AAA aorta and spleen, we discovered heterogeneity among CD4+ T cells and identified...
Source: Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Luna Zhai Wangling Hu Jingyong Li Dan Li Ni Xia Tingting Tang Shaofang Nie Min Zhang Jiao Jiao Bingjie Lv Fen Yang Yuzhi Lu Lingfeng Zha Muyang Gu Xiajun Hu Shuang Wen Desheng Hu Li Zhang Weimin Wang Xiang Cheng Source Type: research
