Two decades of SVT ablation in Denmark: a trend towards higher age, more comorbidity, and less prior use of antiarrhythmic and rate-limiting pharmacotherapy —a nationwide registry-based Danish study
ConclusionBetween 2001 and 2018, CA was increasingly performed in patients with SVT, primarily AVNRT- and EAT patients. The burden of comorbidities increased. Patients undergoing CA without prior antiarrhythmic- or rate-limiting drug therapy increased significantly. Use of beta-blockers increased and remained the most widely used drug.Graphical Abstract (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - December 18, 2023 Category: Cardiology Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Implications of Incorporating Plasma Lipoprotein Binding into a Physiologically-Based Pharmacokinetic Model: A Simulation Study with Amiodarone
This study demonstrates that incorporating plasma lipoprotein binding into a PBPK model improves the accuracy of predicting interindividual variabilities in amiodarone clearance by more reliably predicting the interindividual variability in the plasma unbound fraction of amiodarone. Plasma lipoprotein binding should be considered in PBPK modeling and simulations for lipoprotein-associated drugs if there is available information on the relationship between plasma lipoprotein binding and hyperlipidemia.PMID:38093601 | DOI:10.1002/cpt.3149 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - December 14, 2023 Category: Drugs & Pharmacology Authors: Kosuke Doki Naoaki Hashimoto Keigo Yoshida Masato Homma Source Type: research
Retracted: Application of Amiodarone and Cedilan in the Treatment of Patients with Arrhythmia after Esophageal and Lung Cancer
Evid Based Complement Alternat Med. 2023 Dec 6;2023:9876708. doi: 10.1155/2023/9876708. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2023/8026918.].PMID:38093878 | PMC:PMC10718665 | DOI:10.1155/2023/9876708 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 14, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Implications of Incorporating Plasma Lipoprotein Binding into a Physiologically-Based Pharmacokinetic Model: A Simulation Study with Amiodarone
This study demonstrates that incorporating plasma lipoprotein binding into a PBPK model improves the accuracy of predicting interindividual variabilities in amiodarone clearance by more reliably predicting the interindividual variability in the plasma unbound fraction of amiodarone. Plasma lipoprotein binding should be considered in PBPK modeling and simulations for lipoprotein-associated drugs if there is available information on the relationship between plasma lipoprotein binding and hyperlipidemia.PMID:38093601 | DOI:10.1002/cpt.3149 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - December 14, 2023 Category: Drugs & Pharmacology Authors: Kosuke Doki Naoaki Hashimoto Keigo Yoshida Masato Homma Source Type: research
Retracted: Application of Amiodarone and Cedilan in the Treatment of Patients with Arrhythmia after Esophageal and Lung Cancer
Evid Based Complement Alternat Med. 2023 Dec 6;2023:9876708. doi: 10.1155/2023/9876708. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2023/8026918.].PMID:38093878 | PMC:PMC10718665 | DOI:10.1155/2023/9876708 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 14, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Implications of Incorporating Plasma Lipoprotein Binding into a Physiologically-Based Pharmacokinetic Model: A Simulation Study with Amiodarone
This study demonstrates that incorporating plasma lipoprotein binding into a PBPK model improves the accuracy of predicting interindividual variabilities in amiodarone clearance by more reliably predicting the interindividual variability in the plasma unbound fraction of amiodarone. Plasma lipoprotein binding should be considered in PBPK modeling and simulations for lipoprotein-associated drugs if there is available information on the relationship between plasma lipoprotein binding and hyperlipidemia.PMID:38093601 | DOI:10.1002/cpt.3149 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - December 14, 2023 Category: Drugs & Pharmacology Authors: Kosuke Doki Naoaki Hashimoto Keigo Yoshida Masato Homma Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
