Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats

CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561

Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research