Catheter ablation for monomorphic ventricular tachycardia in Brugada syndrome patients: detailed characteristics and long-term follow-up
ConclusionsAll MVT cases were successfully treated by catheter ablation. We observed high ventricular arrhythmia free rate following catheter ablation during the long-term follow-up period. BrS patients who developed MVT should consider catheter ablation. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - October 12, 2019 Category: Cardiology Source Type: research

Heart failure as a substrate and trigger for ventricular tachycardia
This article provides a review of the aforementioned mechanisms of arrhythmogenesi s in heart failure; the role and impact of HF therapy such as cardiac resynchronization therapy (CRT), including the role, if any, of CRT-P and CRT-D in preventing VAs; the utility of both non-invasive parameters as well as multiple implant-based parameters for telemonitoring in HF; and the effect o f left ventricular assist device implantation on VAs. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - October 9, 2019 Category: Cardiology Source Type: research

Enhanced ventricular tachycardia substrate resolution with a novel omnipolar high-density mapping catheter: the omnimapping study
ConclusionsThe multipolar Advisor ™ HD Grid Mapping Catheter in conWAVE provides more efficient point acquisition and greater VT substrate definition of the borderzone particularly at the low-voltage range compared to conSTANDARD. This greater resolution within the low-voltage range facilitated CC definition and quantification wit hin the scar, which is essential in guiding the ablation strategy. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - October 9, 2019 Category: Cardiology Source Type: research

Impact of mapping points in high-density mapping of the left atrium
AbstractPurposeCurrently, high-density mapping techniques are being discussed for more precise voltage mapping, lesion validation after pulmonary vein isolation (PVI) and superior left atrial tachycardia (LAT) mapping. However, the quality of high-density maps varies according to different mapping systems, multipolar catheter (MPC) types and numbers of mapping points. The aim of this study was to evaluate the impact of different numbers of mapping points in high-density mapping on validity.MethodsFrom February 2016 to August 2018, 154 patients with previous PVI ablation and recurrent atrial fibrillation (AF) or left atrial...
Source: Journal of Interventional Cardiac Electrophysiology - October 2, 2019 Category: Cardiology Source Type: research

Effectiveness of first versus successive antitachycardia pacing attempts: predictors and clinical consequences
AbstractPurposeAntitachycardia pacing (ATP) terminates the majority (but not all) of slow ventricular tachycardias (S-VT) with a cycle length (CL)> 320  ms. Usually, several ATP therapies are programmed in the S-VT zone. Our objective is to analyse the ATP effectiveness, comparing the first ATP attempt (ATP-1) to the second (ATP-2) and third (ATP-3) attempts.MethodsWe studied 556 S-VT (CL = 354 ± 18). ATP programming was standardized and included three bursts of 15 pulses at 91% of VT CL.ResultsATP effectiveness declined from ATP-1 (436/556: 78%) compared to ATP-2 (24/103: 23%) and ATP-3 (10/79: 13%) (p
Source: Journal of Interventional Cardiac Electrophysiology - September 16, 2019 Category: Cardiology Source Type: research

Two-year follow-up of one-stage left unilateral thoracoscopic epicardial and transcatheter endocardial ablation for persistent and long-standing persistent atrial fibrillation
ConclusionThe hybrid one-stage left unilateral thoracoscopic procedure exhibits encouraging results in the setting of both persistent and long-standing persistent AF after a 2-year follow-up, at a low rate of adverse events. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - September 13, 2019 Category: Cardiology Source Type: research

ICD shocks in LVAD patients are not associated with increased subsequent mortality risk
ConclusionsVAs are common in CF-LVAD patients and occur with higher frequency in those with pre-LVAD VA and frequently cause symptoms. Neither VA nor ICD shocks are associated with mortality risk. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - September 10, 2019 Category: Cardiology Source Type: research

CABANA trial: “beauty is in the eye of the beholder”
AbstractThe CABANA trial reported that catheter ablation, when compared with drug therapy, did not significantly reduce the primary composite end point of death, disabling stroke, serious bleeding, or cardiac arrest in patients with atrial fibrillation. Despite multiple limitations in study design, the CABANA trial still confirmed that catheter ablation of atrial fibrillation led to clinically important and significant improvements in quality of life at 12 months without increasing the risk of complications. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - September 6, 2019 Category: Cardiology Source Type: research

European Cardiac Arrhythmia Society Statement on the cardiovascular events associated with the use or abuse of energy drinks
AbstractEnergy drinks are increasingly used by young people and young athletes in order to improve their performance alone or in association of other substances, particularly alcohol. In recent years, a number of reports of reports have raised attention on the side-effects associated with the use or abuse of energy drinks particularly serious cardiovascular events. The European Cardiac Arrhythmia Society (ECAS) has undertaken a systematic and critical review of reported data on cardiovascular events including life-threatening arrhythmias with or without cardiac arrest and other cardiovascular events, and discussed in this ...
Source: Journal of Interventional Cardiac Electrophysiology - September 3, 2019 Category: Cardiology Source Type: research

Prognostic implications of QRS dispersion for major adverse cardiovascular events in asymptomatic women and men: the Multi-Ethnic Study of Atherosclerosis
This study sought to examine the prognostic association between baseline QRS dispersion and future cardiovascular events in individuals without known prior cardiovascular disease.MethodsThe association of QRS dispersion with cardiovascular events was examined in 6510 MESA (Multi-Ethnic Study of Atherosclerosis) participants. Participants with bundle branch block were excluded. Study participants were divided into two groups based on the 95th percentile of QRS dispersion (QRS dispersion
Source: Journal of Interventional Cardiac Electrophysiology - September 3, 2019 Category: Cardiology Source Type: research

The V 1 –V 3 transition index as a novel electrocardiographic criterion for differentiating left from right ventricular outflow tract ventricular arrhythmias
ConclusionsThe V1–V3 transition index is a useful novel ECG criterion for distinguishing left from right OT-VAs with precordial transition in lead V3. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - September 2, 2019 Category: Cardiology Source Type: research

Accuracy of cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm to identify sites of origin of cardiac electrical activation
AbstractWe have developed a system that could potentially be used to identify the site of origin of ventricular tachycardia (VT) and to guide a catheter to that site to deliver radio-frequency ablation therapy. This system employs the Inverse Solution Guidance Algorithm based upon Single Equivalent Moving Dipole (SEMD) localization method. The system was evaluated inin vivo swine experiments. Arrays consisting of 9 or 16 bipolar epicardial electrodes and an additional mid-myocardial pacing lead were sutured to each ventricle. Focal tachycardia was simulated by applying pacing pulses to each epicardial electrode at multiple...
Source: Journal of Interventional Cardiac Electrophysiology - August 27, 2019 Category: Cardiology Source Type: research

Sex effect on efficacy of pulmonary vein cryoablation in patients with atrial fibrillation: data from the multicenter real-world 1STOP project
ConclusionsAccording to the 1STOP project, in a real-world setting, PVI-C was relatively safe regardless of the patient ’s sex; however, when considering efficacy of the procedure, female patients had a lower long-term efficacy in comparison to males.Clinical trial registrationNCT01007474 (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 26, 2019 Category: Cardiology Source Type: research

Very-late onset twiddler syndrome as an unusual cause of syncope
(Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 24, 2019 Category: Cardiology Source Type: research

Analysis of local ventricular repolarization using unipolar recordings in patients with arrhythmogenic right ventricular cardiomyopathy
AbstractPurposeIn arrhythmogenic right ventricular cardiomyopathy (ARVC), abnormal electroanatomic mapping (EAM) areas are proportional to extent of T-wave inversion on 12-lead ECG. We aimed to evaluate local repolarization changes and their relationship to EAM substrate in ARVC.MethodsUsing unipolar recordings, we analyzed the proportion of negative T waves ≥ 1 mV in depth (NegT), NegT area, Q-Tpeak (QTP), Tpeak-Tend (TPE) intervals and their relationship to bipolar (
Source: Journal of Interventional Cardiac Electrophysiology - August 23, 2019 Category: Cardiology Source Type: research

Single- and dual-site ventricular pacing entirely through the coronary sinus for patients with prior tricuspid valve surgery
ConclusionsThe use of ventricular pacing entirely through the CS is an effective and minimally invasive method that provides stable pacing for patients with prior TV surgery in whom transvenous lead placement either is not possible or is relatively contraindicated. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 20, 2019 Category: Cardiology Source Type: research

Electrophysiology devices and the regulatory approval process within the U.S. FDA and abroad
AbstractAlmost all electrophysiology (EP) devices need to obtain premarket approval before they can be commercially sold and available for use in the community. The US Food and Drug Administration (FDA) has different paths to market approval depending on the intended use and the associated risks of the device. The European Union and Japan have device approval processes that have many similarities as well as differences to the US regulatory system. This paper describes some of the history and background of the US device approval process with an emphasis on EP devices. It provides an overview of the different regulatory path...
Source: Journal of Interventional Cardiac Electrophysiology - August 16, 2019 Category: Cardiology Source Type: research

Novel AKAP9 mutation and long QT syndrome in a patient with torsades des pointes
(Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 15, 2019 Category: Cardiology Source Type: research

Left atrial wall thickness is associated with the low-voltage area in patients with paroxysmal atrial fibrillation
AbstractPurposeTo identify a potential morphological marker of remodeling and electrophysiological dysfunction, we investigated if low wall thickness is associated with low-voltage areas (LVAs) in the left atrium.MethodsWall thickness was measured by computed tomography and LVA (% area with bipolar voltage  10% of segment surface area) was observed in 123 of 215 segments (57%). Segments in the low tertile of wall thickness (
Source: Journal of Interventional Cardiac Electrophysiology - August 13, 2019 Category: Cardiology Source Type: research

Bipolar radiofrequency ablation delivered from coronary veins and adjacent endocardium for treatment of refractory left ventricular summit arrhythmias
ConclusionsBipolar RFCA from coronary veins and an opposite endocardium can be used for safe and successful treatment of PVC/VT originating from a deep LV summit. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 11, 2019 Category: Cardiology Source Type: research

Lateral tunnel Fontan atrial tachycardia ablation trans-baffle access is not mandatory as the initial strategy
ConclusionsCatheter ablation can be performed effectively for ATs in LTF patients usually from inside the tunnel. ATs with critical sites in the PVA are uncommon. This information will help plan ablation in LTF patients without resorting to initial trans-baffle access. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 9, 2019 Category: Cardiology Source Type: research

Prospective evaluation of iatrogenic atrial septal defect after cryoballoon or radiofrequency catheter ablation of atrial fibrillation —“EVITA” study
ConclusionPersistent IASD can occur rather frequently following AF CA. No significant difference was observed between the RF and CB techniques concerning the presence of IASD at 3-month. IASDs showed a high spontaneous closure rate. No cerebral thromboembolic event was observed in the 12-month FU period. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 9, 2019 Category: Cardiology Source Type: research

A subvalvular catheter approach for radiofrequency ablation of right-sided accessory pathways
ConclusionCatheter ablation of RAPs using a subvalvular approach seems as effective and safe compared with conventional ablation but with reduced procedure time and radiation exposure and might be at least considered an alternative after failed conventional catheter ablation of RAPs. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 5, 2019 Category: Cardiology Source Type: research

Safety and feasibility of combined atrial fibrillation ablation and left atrial appendage occlusion after left atrial appendage electrical isolation
ConclusionA combined procedure is feasible and effective in treating arrhythmia and stroke risk associated with PLAF. The risk of TE despite OAC after LAAEI supports simultaneous LAAO. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 3, 2019 Category: Cardiology Source Type: research

Determinants of inappropriate implantable cardioverter-defibrillator shocks: the German Device Registry perspective
ConclusionIn a contemporary setting, some specific conditions such as VVI-ICD, younger age, and faster resting heart rates remain important IS determinants after ICD implantation. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 2, 2019 Category: Cardiology Source Type: research

Development of a novel ablation hood to prevent systemic embolization of microbubbles and particulate emboli
ConclusionsUse of a novel hood to cover the ablation catheter at the site of catheter-tissue contact has the potential to provide a means to reduce systematic embolization of microbubbles. Further work is required to examine particulate emboli, but these data show the early feasibility of this design concept. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - August 2, 2019 Category: Cardiology Source Type: research

Japan ablation registry: cryoablation in atrioventricular nodal reentrant tachycardia ( “JARCANRET study”): results from large multicenter retrospective investigation
ConclusionsCryoablation of AVNRT appears to be effective both acutely and during the long-term with a minimal risk of unwanted injuries to the conduction system. It seems to be important to monitor the antegrade conduction during cryoenergy applications, even when cryomapping demonstrates a safe location for cryoablation. The recurrence rate of AVNRT did not differ according to the properties of the residual slow pathway conduction. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 31, 2019 Category: Cardiology Source Type: research

Incidence and predictors of pacemaker-induced cardiomyopathy with comparison between apical and non-apical right ventricular pacing sites
ConclusionsIncidence of PiCMP with RV pacing was found to be 13.8% over a mean follow-up of 14.5  months. Burden of right ventricular pacing and interventricular dyssynchrony were identified as the most important predictors for the development of PiCMP. Non-apical RV pacing site did not offer any benefit in terms of incidence of PiCMP over apical lead position. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 30, 2019 Category: Cardiology Source Type: research

PV isolation guided by esophageal visualization with a tailored ablation strategy for the avoidance of esophageal thermal injury: a randomized trial
ConclusionsEsophageal contrast visualization helps to reduce the potential for esophageal injury during paroxysmal AF ablation. This simple procedural adjunct has important implications to improve safety of paroxysmal AF ablation procedures globally. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 26, 2019 Category: Cardiology Source Type: research

Persistent atrial fibrillation: should we always ice the back of the left atrium?
(Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 24, 2019 Category: Cardiology Source Type: research

Needle aspiration for treating iatrogenic pneumothorax after cardiac electronic device implantation: a pilot study
ConclusionsOur data suggest that in a number of patients iatrogenic PTX may be successfully treated with NA resulting in shorter hospitalization without the risk of meaningful discharge delay in unsuccessful cases. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 24, 2019 Category: Cardiology Source Type: research

Do all intra-ventricular conduction defect ECG patterns respond equally to CRT?
ConclusionPatients with ALBBB may have a favorable echocardiographic response to CRT and display similar survival rates to typical LBBB. This subgroup of IVCD should be considered for CRT.Condensed abstractAtypical left bundle branch morphology defined as QS or rS in lead V1, broad R waves in lead I, and aVL but with QS or rS in V5 –V6 is associated with favorable echocardiographic response to CRT and displays similar survival rates to typical LBBB patients. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 23, 2019 Category: Cardiology Source Type: research

CHA 2 DS 2 -VASc score predicts 30-day readmission due to thromboembolic complications following cardioversion of atrial fibrillation: insights from US National Readmissions Database
ConclusionsThis study demonstrated the utility of CHA2DS2-VASc score in predicting TEC-associated readmission rate following CV and the temporal relationship of TEC to CV. Patients>  65 years old without other comorbidities may benefit from 30-day OAC following successful CV irrespective of the duration of AF episodes. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 22, 2019 Category: Cardiology Source Type: research

A novel risk model for very late return of atrial fibrillation beyond 1  year after cryoballoon ablation: the SCALE-CryoAF score
ConclusionSCALE-CryoAF is the first risk model to specifically predict first recurrence of AF beyond 1  year, VLRAF, after CBA. Model discrimination demonstrates that SCALE-CryoAF predicts VLRAF after CBA significantly better than other risk models for AF recurrence. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 20, 2019 Category: Cardiology Source Type: research

Porous tip contact force –sensing catheters for pulmonary vein isolation: performance in a clinical routine setting
AbstractPurposeIn catheter ablation of atrial fibrillation (AF), contact force (CF) –sensing catheters with an irrigated tip are used to deliver radiofrequency (RF) energy to the tissue. The ThermoCool® Smarttouch™ Surroundflow catheter (STSF) integrates CF-sensing technology and a new porous tip for advanced external cooling. The aim was to evaluate the performance and safety of STSF in a clinical setting of pulmonary vein isolation (PVI) in comparison with standard contact force–sensing catheter (ST).MethodsWe assigned consecutive patients (n = 80, prospectively, open-label, non-random...
Source: Journal of Interventional Cardiac Electrophysiology - July 19, 2019 Category: Cardiology Source Type: research

Usefulness of an I Kr blocker for ablation of non-pulmonary vein ectopies that are unmappable due to easily initiated atrial fibrillation
ConclusionNifekalant administration appears useful in the ablation of non-PV ectopies that easily initiate AF. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 18, 2019 Category: Cardiology Source Type: research

Multisite pacing via a quadripolar lead for cardiac resynchronization therapy
AbstractCardiac resynchronization therapy is challenging. Up to 40% of patients are non-responder. Multisite pacing via a quadripolar lead, also called multipoint/multipole pacing (MPP), is a debated alternative. In this review, we summarize evidence in the literature, tips and pitfalls related to MPP programming, and the different algorithms of MPP in different manufacturers. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 18, 2019 Category: Cardiology Source Type: research

An ablation index operator-independent approach to improve efficacy in atrial fibrillation ablation at 24-month follow-up: a single center experience
ConclusionsAI-guided ablation results more effective than CF-guided ablation as demonstrated by a lower incidence of AF recurrences regardless of the use of antiarrhythmic drugs in the follow-up. Each operator seems to improve the long-term success using an AI-guided ablation, thus showing both the efficacy and the reproducibility of this approach. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 16, 2019 Category: Cardiology Source Type: research

Irreversible electroporation for catheter-based cardiac ablation: a systematic review of the preclinical experience
ConclusionPreclinical studies suggest that cardiac tissue ablation using IRE shows promise in delivering efficacious, safe lesions. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - July 3, 2019 Category: Cardiology Source Type: research

Cardiac perforation complicating cardiac electrophysiology procedures: value of angiography and use of a closure device to avoid cardiac surgery
ConclusionsAngiography may be more accurate than CT in the diagnosis of CP. Angiography is easy to perform, can be done acutely, reveals active leaks and can demonstrate sealing of perforations after percutaneous lead repositioning. Utilisation of a PDA closure device may avoid the need for surgery for RV perforation. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 28, 2019 Category: Cardiology Source Type: research

Initial experience with a novel re-sterilisable decapolar electrophysiology catheter
ConclusionsThis initial study of an innovative, partially reusable, steerable decapolar electrophysiology catheter demonstrates that it may be used safely and successfully. Use of such a catheter may decrease the cost required for electrophysiology studies. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 25, 2019 Category: Cardiology Source Type: research

Efficacy and safety of catheter ablation of atrioventricular nodal re-entrant tachycardia by means of flexible-tip irrigated catheters
ConclusionsIrrigated RF ablation of AVNRT by means of the novel flexible-tip open-irrigated catheter associated to 3D EAM system is effective and safe. Success rates are comparable to those of other techniques. Complication rate is very low. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 24, 2019 Category: Cardiology Source Type: research

Long-term left atrial remodeling after ablation of persistent atrial fibrillation: 7-year follow-up by cardiovascular magnetic resonance imaging
AbstractPurposeRestoration of sinus rhythm in patients with persistent atrial fibrillation (ps. AF) induces reverse atrial remodeling and improvement of left ventricular function. We evaluated the effect of ablative treatment on cardiac remodeling after a long follow-up period of 7  years by cardiovascular magnetic resonance (CMR).MethodsPatients with symptomatic ps. AF underwent CMR within 7  days prior to the ablation procedure. Left atrial and ventricular volumes were measured. All patients underwent circumferential pulmonary vein isolation. At the end of follow-up (FU), a CMR and 7-day ECG registration were p...
Source: Journal of Interventional Cardiac Electrophysiology - June 22, 2019 Category: Cardiology Source Type: research

Higher initial weight-based heparin dosing is required with direct oral anticoagulants during catheter ablation for atrial fibrillation
ConclusionPatients on DOACs require more heparin during AF ablation to achieve therapeutic ACT. We suggest an initial heparin dose of at least 150  units/kg in this subset of patients, particularly in those with a weight>  90 kg. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 22, 2019 Category: Cardiology Source Type: research

Effect of fibrotic capsule debridement during generator replacement on cardiac implantable electronic device infection risk
ConclusionsCapsule debridement during CIED replacement was associated with a significant reduction of CIED infection risk. There is a need for randomized controlled studies to confirm these findings. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 21, 2019 Category: Cardiology Source Type: research

Identification of precise accessory pathway using ultra-high-resolution three-dimensional mapping system: utility and feasibility in preliminary experience
(Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 21, 2019 Category: Cardiology Source Type: research

Differential effect with septal and apical RV pacing on ventricular activation in patients with left bundle branch block assessed by non-invasive electrical imaging and in silico modelling
ConclusionsRVAP activation differs from LBBB where RVSP appears similar.Trial registration(ClinicalTrials.gov identifier: NCT01831518) (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - June 14, 2019 Category: Cardiology Source Type: research

Prediction of acute coronary syndrome, ischemic stroke, and mortality in patients with heart failure: a comparison of CHA 2 DS 2 -VASc and AHEAD scores
AbstractPurposeTo compare the predictive capacity of the CHA2DS2-VASc and AHEAD scores in predicting acute coronary syndrome (ACS), ischemic stroke (IS), and mortality in patients with heart failure (HF).MethodsA total of 404,635 patients hospitalized for HF between 2000 and 2011 were recruited from a large national database in Taiwan. The predictive value of both scores was evaluated by analysis of the area under the receiver operating characteristic curve (AUROC), and the difference in their discriminative capacity was assessed using the DeLong test.ResultsThe AUROC for the CHA2DS2-VASc score was significantly higher tha...
Source: Journal of Interventional Cardiac Electrophysiology - June 14, 2019 Category: Cardiology Source Type: research

Different characteristics of postoperative atrial tachyarrhythmias between congenital and non-congenital heart disease
We examined the characteristics of atrial tachyarrhythmias (ATs) in 26 consecutive CHD patients (M/F 17/9) referred for catheter ablation and compared them with 16 non-CHD patients with cardiac surgery (M/F 11/5).ResultsThe CHD group was younger and had a longer period from cardiac surgery until the occurrence of ATs compared with the non-CHD group (44.8  ± 19.5 vs. 67.6 ± 12.5 years old, and 23.3 ± 13.2 vs. 6.3 ± 4.9 years, respectively, bothP 
Source: Journal of Interventional Cardiac Electrophysiology - June 13, 2019 Category: Cardiology Source Type: research

Reverse electrical and structural remodeling of the left atrium occurs early after pulmonary vein isolation for persistent atrial fibrillation
AbstractPurposeAdverse left atrial (LA) remodeling is known to be associated with persistent atrial fibrillation (PeAF). The time course and pattern of reversal of LA remodeling following catheter ablation is poorly understood. We aimed to evaluate LA chamber volumes and dimensions, LA conduction velocities, and LA bipolar voltages at baseline and at 2  months after catheter ablation for PeAF.MethodsTwenty-three patients with PeAF underwent detailed LA mapping during fixed rate atrial pacing using the CARTO3 navigation system prior to undergoing pulmonary vein isolation. All patients returned for protocol-mandated rep...
Source: Journal of Interventional Cardiac Electrophysiology - June 13, 2019 Category: Cardiology Source Type: research