Allergic reactions to cow's milk proteins in medications in childhood.
CONCLUSIONS: We suggest caution in administration of pharmaceuticals containing milk allergens in children allergic to milk.
PMID: 30830066 [PubMed - in process] (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - January 28, 2019 Category: General Medicine Authors: Santoro A, Andreozzi L, Ricci G, Mastrorilli C, Caffarelli C Tags: Acta Biomed Source Type: research
Safety of Iohexol Administration to Measure Glomerular Filtration Rate in Different Patient Populations: A 25-Year Experience
Conclusion: Iohexol administration for GFR measurement is a safe procedure, even in repeated investigations in the same subject, that should be adopted in clinical research and, when needed, also in clinical practice.Nephron (Source: Nephron)
Source: Nephron - May 17, 2018 Category: Urology & Nephrology Source Type: research
Nebulization of Cyclic Arginine-Glycine-(D)-Aspartic Acid-Peptide Grafted and Drug Encapsulated Liposomes for Inhibition of Acute Lung Injury
ConclusionFrom the results, it can be inferred that nebulization of targeted liposomes had facilitated spatial and temporal modulation of drug delivery resulting in alleviation of ALI. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - March 13, 2018 Category: Drugs & Pharmacology Source Type: research
Malignant atrophic papulosis with motor aphasia and intestinal perforation: A case report and review of published works
We present a 30‐year‐old female patient with systemic manifestation of MAP 10 days after delivery of a full‐term pregnancy who subsequently developed motor aphasia and intestinal perforation. The patient was administrated empirical treatment with an antiplatelet, anticoagulant, methylprednisolone sodium succinate and alprostadil. Antibiotics were administrated due to intestinal perforation and secondary sepsis. Despite all treatment, the patient died a week later. We summarized all the previous reports of MAP based on thorough review of previous published work. Overall, this is the first patient with MAP combined wit...
Source: The Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Pan Hu, Zhi Mao, Chao Liu, Xin Hu, Hongjun Kang, Feihu Zhou Tags: Concise Communication Source Type: research
Mechanism of Neuroprotection Against Experimental Spinal Cord Injury by Riluzole or Methylprednisolone.
Abstract
Any spinal cord injury carries the potential for persistent disability affecting motor, sensory and autonomic functions. To prevent this outcome, it is highly desirable to block a chain of deleterious reactions developing in the spinal areas immediately around the primary lesion. Thus, early timing of pharmacological neuroprotection should be one major strategy whose impact may be first studied with preclinical models. Using a simple in vitro model of the rat spinal cord it is possible to mimic pathological processes like excitotoxicity that damages neurons because of excessive glutamate receptor ...
Source: Neurochemical Research - December 30, 2017 Category: Neuroscience Authors: Sámano C, Nistri A Tags: Neurochem Res Source Type: research
Safety of intrathecal route: focus to methylprednisolone acetate (Depo-Medrol) use
ConclusionsIntrathecal methylprednisolone acetate (Depo-Medrol) therapy seems not fully safe due to reported adverse events. The use of other forms of corticosteroid therapy free from excipients should be emphasized such as soluble methylprednisolone sodium succinate. (Source: European Spine Journal)
Source: European Spine Journal - November 18, 2017 Category: Orthopaedics Source Type: research
Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow ’s milk allergy
ConclusionChildren who are highly sensitive to milk may have severe allergic reactions also after exposure to CMP through a different administration route than the oral one. Patients who have food allergies need to pay particular attention to the prescription of drugs and their formulation. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - November 17, 2017 Category: Pediatrics Source Type: research
Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow ’s milk allergy
Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow ’s milk proteins (CMP), could cause allergic reactions or compromise treatment of acute allergi... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - November 17, 2017 Category: Pediatrics Authors: Federica Porcaro, Maria Giovanna Paglietti, Antonella Diamanti, Francesca Petreschi, Alessandra Schiavino, Valentina Negro, Valentina Pecora, Alessandro Fiocchi and Renato Cutrera Tags: Case report Source Type: research
Autoimmune hemolytic anemia associated with trimethoprim-sulfamethoxazole use.
CONCLUSION: A 58-year-old woman developed warm autoimmune hemolytic anemia after receiving trimethoprim-sulfamethoxazole for 5 days.
PMID: 28596226 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - June 11, 2017 Category: Drugs & Pharmacology Authors: Frieder J, Mouabbi JA, Zein R, Hadid T Tags: Am J Health Syst Pharm Source Type: research
The role of low level laser therapy on neuropathic pain relief and interleukin-6 expression following spinal cord injury; an experimental study
Conclusion Findings show that long periods of LLLT have better effects in improving the complication of SCI. In summation, since LLLT does not cause the side effects of MPSS, long-term use of LLLT may be a proper alternative for MPSS in decreasing post SCI side effects. (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 18, 2017 Category: Neuroscience Source Type: research
Adult onset Still's disease accompanied by acute respiratory distress syndrome: A case report.
In conclusion, in a patient with ARDS who does not respond to antibiotic treatment, the involvement of AOSD should be considered.
PMID: 27588099 [PubMed - as supplied by publisher] (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - September 3, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research
Is the Wnt/β-catenin pathway involved in the anti-inflammatory activity of glucocorticoids in spinal cord injury?
The Wnt canonical or the Wnt/β-catenin pathway has been implicated in the regulation of several physiopathological pathways such as inflammation. Glucocorticoids (GCs) are administered widely to treat inflammation in several diseases, including spinal cord injury (SCI). The aim of this study was to evaluate whether the Wnt canonical pathway is involved in experimental SCI and whether it is implicated in the anti-inflammatory activity of two different GCs: the methylprednisolone sodium succinate (MPSS), considered the standard treatment for acute SCI, and mometasone furoate (MF), mainly administered for the treatment of ai...
Source: NeuroReport - September 2, 2016 Category: Neurology Tags: Cellular Molecular and Developmental Neuroscience Source Type: research
Relation between the development of osteoporosis and osteonecrosis following glucocorticoid in a rabbit model
Conclusion: A rabbit model of GC-induced OP and ON was developed by repetitive injection with small doses of GCs in the gluteal region. OP was observed at 4 weeks while ON developed at 8 weeks and followed a clear temporal pattern. (Source: Indian Journal of Orthopaedics)
Source: Indian Journal of Orthopaedics - July 5, 2016 Category: Orthopaedics Authors: Tao LinJunbin LiuShuhua YangXianzhe LiuXiaobo FengDehao Fu Source Type: research
Henoch-Schönlein purpura following high-voltage electric burn injury: A case report and review of the literature.
Authors: Duan X, Yu D, Yu C, Wang B, Guo Y
Abstract
Henoch-Schönlein Purpura (HSP) is a systemic vasculitis of unknown cause, with immune-mediated inflammation of the small vessels, which is characterized by a series of clinical symptoms, such as purpuric rash, colicky abdominal pain, arthritis and acute glomerulonephritis. Twenty-one days following a high-voltage electrical burn injury, a 40-year-old man developed classic clinical symptoms of HSP, including purpuric rash on bilateral lower extremities and abdominal pain. The patient was diagnosed with HSP associated with high-voltage burn injury, which i...
Source: Experimental and Therapeutic Medicine - February 21, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research
A study of methylprednisolone neuroprotection against acute injury to the rat spinal cord in vitro
Publication date: 19 February 2016 Source:Neuroscience, Volume 315 Author(s): C. Sámano, J. Kaur, A. Nistri Methylprednisolone sodium succinate (MPSS) has been proposed as a first-line treatment for acute spinal cord injury (SCI). Its clinical use remains, however, controversial because of the modest benefits and numerous side-effects. We investigated if MPSS could protect spinal neurons and glia using an in vitro model of the rat spinal cord that enables recording reflexes, fictive locomotion and morphological analysis of damage. With this model, a differential lesion affecting mainly either neurons or glia can...
Source: Neuroscience - January 13, 2016 Category: Neuroscience Source Type: research
