Molecules, Vol. 26, Pages 5163: Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment

Molecules, Vol. 26, Pages 5163: Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment Molecules doi: 10.3390/molecules26175163 Authors: Rakesh K. Sindhu Rishu Verma Twinkle Salgotra Md. Habibur Rahman Muddaser Shah Rokeya Akter Waheed Murad Sidra Mubin Parveen Bibi Safaa Qusti Eida M. Alshammari Gaber El-Saber Batiha Michał Tomczyk Hayder M. Al-kuraishy Breast cancer persists as a diffuse source of cancer despite persistent detection and treatment. Flavonoids, a type of polyphenol, appear to be a productive option in the treatment of breast cancer, because of their capacity to regulate the tumor related functions of class of compounds. Plant polyphenols are flavonoids that appear to exhibit properties which are beneficial for breast cancer therapy. Numerous epidemiologic studies have been performed on the dynamic effect of plant polyphenols in the prevention of breast cancer. There are also subclasses of flavonoids that have antioxidant and anticarcinogenic activity. These can regulate the scavenging activity of reactive oxygen species (ROS) which help in cell cycle arrest and suppress the uncontrolled division of cancer cells. Numerous studies have also been performed at the population level, one of which reported a connection between cancer risk and intake of dietary flavonoids. Breast cancer appears to show intertumoral heterogeneity with estrogen receptor positive and negative cells. This review d...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research