Thrombotic microangiopathy and liver toxicity due to a combination therapy of leflunomide and methotrexate: a case report
ConclusionsUnder a combination of leflunomide and methotrexate, liver toxicity and, for the first time, thrombotic microangiopathy occurred as side effects. Non-alcoholic fatty liver disease may have predisposed for the drug-induced liver toxicity.
The FDA advises against metformin use in hepatic impairment because of the risk of inducing lactic acidosis. Is this warning warranted?Alimentary Pharmacology &Therapeutics
CONCLUSIONS These results indicate that GDLP against T2DM-induced hepatic steatosis, oxidative stress, and inflammation by improving the Nrf2/HO-1 signaling pathway in db/db mice, suggesting the GDLP may serve as an effective strategy for in fatty liver treatment. PMID: 32245940 [PubMed - as supplied by publisher]
Conclusions: Craniomaxillofacial metastases, usually with multiple visceral or axial skeleton lesions, have an ominous prognosis. Multidisciplinary management could benefit the patient status and lead to more favourable outcomes. There are exceptional cases of long-term survival.RESUMEN Objetivo: Estudio descriptivo retrospectivo de 21 casos de met ástasis en tejidos blandos orales y/o huesos maxilares. Material y métodos: Revisión a 12 años de actas de nuestro departamento, excluyendo procesos linfoproliferativos, metástasis cutáneas, glándulas salivales, otros huesos crane...
Publication date: Available online 4 April 2020Source: Journal of Ayurveda and Integrative MedicineAuthor(s): Naresh Kumar P, Ragavendrasamy Balakrishnan, Vibhas Kana
UK-based biopharma company Izana Bioscience said it was testing its antibody therapy namilumab for the treatment of patients with rapidly worsening COVID-19 at the Humanitas Research Hospitals in Bergamo and Milan in Italy.
Barbados on Sunday reported its first death from the new coronavirus after an 81-year-old man with diabetes died from pneumonia, the country's health minister said.
AbstractPurposeTo assess the spectrum of computed tomography (CT) findings in patients with genitourinary cancers visiting the emergency room (ER) and evaluate the relationship between CT findings and overall survival (OS).MethodsRetrospective analysis of consecutive patients with genitourinary cancers undergoing CT during an ER visit at a tertiary cancer center during a 20-month period. CTs were considered positive if there were findings relevant to the presenting complaint(s). Demographic/clinical variables were recorded. OS was evaluated using Kaplan-Meier curves. Univariate and multivariate Cox proportional hazards reg...
(Natural News) Keeping your immune system strong and healthy is important since it protects you from germs that can make you sick. There are many ways to boost your immunity, such as eating nutritious foods, taking vitamin supplements and exercising regularly. Getting enough sleep each night is also key to supporting immune health and overall...
TYPE 2 diabetes requires one to lead a healthy lifestyle to keep blood sugar levels under control. Since exercise plays a key role in controlling blood sugar levels, the current lockdown poses a threat to type 2 diabetes management. Luckily, there is a simple activity you can do from the comfort of your home that has proven to lower post-meal blood sugar levels.
Publication date: Available online 4 April 2020Source: Journal de Mycologie MédicaleAuthor(s): Elie Djenontin, David Lebeaux, Hans Acikgoz, Blandine Rammaert, Marie-Elisabeth Bougnoux, Claire Rouzaud, Benjamin Bouyer, Benoit Champigneulle, Eric Dannaoui
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