Blood-thinning drugs may reduce dementia risk in people with irregular heartbeats

Conclusion If you’ve been diagnosed with AF and you have been prescribed anticoagulant treatments such as warfarin or clopidogrel, we already know they protect you against having a stroke. This study suggests they may also help to protect you against dementia. Cutting the risk of dementia for people who have a raised risk because of AF would be an exciting step forward. Unfortunately, we can’t tell from this study whether the protection against dementia was down to the anticoagulants, because of the possible effect of unmeasured confounding factors. Usually, we would want to see a randomised controlled trial (RCT) to follow this study, to find out if anticoagulant drugs really do have that effect. However, because people with AF are usually prescribed anticoagulants to reduce their risk of stroke, it would not be ethical to do an RCT, as it would leave people unprotected against stroke when a known preventive treatment is available. Because of the difficulties of carrying out a proper trial, we will need to see more studies of the kind done here, in different populations, to see whether the results hold true. It would be useful in future studies to have clearer information about which confounding factors are being taken into account. There are a few things we don’t know from this study. The researchers were unable to differentiate between types of AF. Some people have just one episode of AF that doesn’t return, or goes away with treatment, while others...
Source: NHS News Feed - Category: Consumer Health News Tags: Neurology Source Type: news

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Authors: Feres M, Retamal-Valdes B, Faveri M, Duarte P, Shibli J, Soares GMS, Miranda T, Teles F, Goodson M, Hasturk H, Van Dyke T, Ehmke B, Eickholz P, Schlagenhauf U, Meyle J, Koch R, Kocher T, Hoffmann T, Kim TS, Kaner D, Figueiredo LC, Doyle H Abstract OBJECTIVE: The selection of proper outcome measures is a critical step in clinical research. Most randomized clinical trials (RCTs) assessing the effects of initial anti-infective periodontal therapies use surrogate outcomes as primary outcome variables, such as mean changes in probing depth (PD) or in clinical attachment. However, these parameters do not reflect...
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
CONCLUSIONS: Non-surgical periodontal therapy was effective during the first 18 months, but periodontal conditions were worse at 48 months after therapy. The distal sites of abutment teeth with direct retainers presented the worst periodontal conditions. PMID: 32224546 [PubMed - in process]
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
Publication date: Available online 31 March 2020Source: Journal of Sound and VibrationAuthor(s): Ge Yan, Hong-Xiang Zou, Sen Wang, Lin-Chuan Zhao, Qiu-Hua Gao, Ting Tan, Wen-Ming Zhang
Source: Journal of Sound and Vibration - Category: Physics Source Type: research
No abstract available
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: Research Reports: Case Study Source Type: research
This study evaluated a novel composite measure of health literacy and numeracy by assessing its predictive validity for diabetes self-care activities and glycemic control. Methods: Patients (N = 102) with type 2 diabetes were recruited from a family medicine clinic at an academic medical center. Combined health literacy was assessed by combining the results of the Health Literacy Scale and the Subjective Numeracy Scale. Self-management activities were assessed by the Summary of Diabetes Self-Care Activities scale. Hemoglobin A1c (A1c) values were extracted from patients' medical records to assess glycemic control. Path ...
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: Research Reports: Research Full Report Source Type: research
In this study, we examined the effect of laparoscopic-guided transversus abdominis plane block (LG TAP) for further optimizing multimodal pain control.MethodsThis is a retrospective analysis of a prospectively collected database of 140 consecutive patients undergoing LSG without TAP block (pre-TAP group) compared to 131 patients undergoing LSG with LGTAP (TAP group). All operations were performed laparoscopically utilizing uniform clinical pathways. Baseline characteristics for both groups were comparable. Both groups received standardized anesthesia. Outcomes included time to postoperative ambulation, pain scores, PCA vol...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsThis is the first report of cognitive improvements following VSG and the first direct comparison of cognitive improvements following RYGB and VSG. Short-term improvements in specific domains of cognitive function are observed at the beginning of the active weight loss phase following bariatric surgery that persisted to 3  months. The anatomical distinction between the two surgeries and resulting differential metabolic profiles may be responsible for the improvements in attention observed following RYGB but not following VSG.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsWeight loss after EGJR is sustained up to 5  years after revision with little effect on medical comorbidities. Patients with a greater reduction in stoma diameter experienced superior weight loss.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
In this study, wound-related outcomes are examined, comparing patients who underwent surgery before (Group 1) versus after (Group 2) this intervention. Statistical analysis performed utilizingt tests and Chi square analysis;p 
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsConversion of prior Nissen fundoplication to RnY anatomy is technically challenging, although it is safe and feasible even in the setting of multiple prior foregut operations. A minimally invasive approach should be offered to patients by surgeons with experience in revisional foregut and bariatric surgery.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
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