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How Common Are STIs?

Discussion Of the 30 different microbes which can be transmitted by sexual contact, 8 have the greatest incidence of transmitting disease. Four are curable (Chlamydia, Gonorrhea, Syphilis and Trichomoniasis) and 4 are incurable at present (Hepatitis B, Herpes simplex virus (HSV), Human immunodeficiency virus (HIV) and Human papillomavirus (HPV)). Sexually transmitted infections (STIs) are important as they can cause: Increased rates of acquisition of other STIs (ie HSV and syphilis increase the rate of HIV infection acquisition) Pelvic inflammatory disease and infertility Stillbirth and neonatal death Neonatal morbidity including low-birth weight, prematurity, conjunctivitis, pneumonia, sepsis, and congenital abnormalities Genital cancer In high-income countries diagnosis usually includes laboratory testing and then treatment. Short-course antibiotic treatment for curable infections is effective. In low- and middle-income countries laboratory testing is often cost prohibitive and the diagnosis is made by syndromic management using symptoms and guidelines to direct care. Syndromic management is good as patients can be treated the same day, but the majority of STIs are not detected because patients are asymptomatic. Preventative vaccines for Hepatitis B and HPV have and are showing high prevention rates. Other vaccines are also being developed. Other interventions show that male circumcision decreases the risk of heterosexually transmitted HIV infection and may provide some ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

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Authors: Jungels C, Martinez Chanza N, Albisinni S, Mercier M, d'Haene N, Rorive S, Roumeguère T Abstract OBJECTIVES: There are only few predictive factors for response of non-musculo-invasive bladder cancer (NMIBC) to Bacillus Calmette-Guérin (BCG) therapy. Our study analyzed the results of the sequencing of new generation (NGS) targeted on 50 genes of oncological interest obtained on bladder resection parts in high-risk NMIBC patients treated with BCG, to describe this population from a molecular point of view and try to correlate these results in patients who present or not recurrence after BCG. ...
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Abstract Supercritical fluid chromatography (SFC) is already used for enantioseparation in the pharmaceutical industry, but it is rarely used for the separation of chiral pesticides. Comparing with high performence liquid chromatography, SFC uses much more environmnetal friendly and economic mobile phase, supercritical CO2 . In our work, the enantioseparation of an amide herbicide, napropamide, using three different polysaccharide-type chiral stationary phases (CSPs) in SFC was investigated. By studying the effect of different CSPs, organic modifiers, temperature, back-pressure regulator pressures, and flow rates ...
Source: Chirality - Category: Molecular Biology Authors: Tags: Chirality Source Type: research
Ultrasound technique overcomes problems with current methods to diagnose the most common cancer in menScientists have announced the development of a highly accurate and reliable technique for diagnosing prostate cancer. The Dundee University-based team say they have used an ultrasound process called shear wave elastography (SWE) to detect prostate tumours. The method is non-invasive and cheaper than current detection techniques.Prostate cancer has become the most common cancer in men in the UK. One in eight men will develop the condition at some point in their lives with more than 47,000 new cases being diagnosed every yea...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Prostate cancer Health Society UK news Medical research Science Men's health & wellbeing Life and style Source Type: news
Medical research is reaching a new frontier with implants that can accurately spot early signs of cancer. Yet the road from laboratory to patient is long.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
This article provides an up-to-date review of biomarkers with promising characteristics to be prognostic markers for CCA reported in the past 5 years. The biomarkers are sub-classified into tissue and serum markers. Proteins, RNAs, peripheral blood cells etc., that are associated with aggressive phenotypes, signal pathways, chemo-drug resistance and those that reflect the survival time of CCA patients are evaluated for their prognostic prediction values. Expert commentary: CCAs are heterogeneous tumors of different histo-pathological subtypes and genetic influences and, therefore, potential markers should be validated in l...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
This article explores the public dying of journalist, writer, provocateur, public intellectual, and renowned atheist, Christopher Hitchens. It does so primarily through an analysis of television interviews given by Hitchens following his diagnosis with esophageal cancer in June 2010. Four key themes are identified as emerging from analysis of the interviews: (a) Hitchens' explicit sense of mission in challenging myths and superstitions surrounding cancer, dying, and death; (b) the personal experience of terminal illness and dying and the particular way (or style of dying) by which it is approached; (c) issues of regret and...
Source: Omega - Category: Palliative Care Authors: Tags: Omega (Westport) Source Type: research
Authors: Galluzzo M, D'Adamio S, Bianchi L, Talamonti M Abstract Psoriasis tends to improve for approximately half of patients during pregnancy, but an equal number of patients report no change or worsening during this period, when lots of medications, like biologics, are not indicated. The aim of our study was to review data of patient that had been pregnant during ustekinumab treatment, analyzing data of our data set between September 2010 and February 2018. We found data of three patients that had been pregnant during ustekinumab treatment. All three patients successfully completed the pregnancy without complica...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
We think nothing of sharing personal information with tech giants so why are we so suspicious about our health records?Half of us born after 1960 will be told we havecancer at some point in our lives. Virtually no one will go through life untouched by the disease, whether as a sufferer, a survivor or supporter. So every year, millions of us lace up running shoes, bake cakes and cultivate moustaches in memory of loved ones to raise the cash needed for cancer research.But money is not the only critical ingredient in developing new cures. An important constraint on the pace of progress is the lack of large datasets that conta...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Tessa Jowell Cancer Cancer research Data protection Science Health Politics UK news Source Type: news
CONCLUSIONS: High-risk drinkers may be unresponsive to anticipated regret manipulations as they do not regret post-alcohol "bad" experiences, and some regrets were associated with comparative optimism. Interventions may need to focus less on regret and aim to change risk perceptions. PMID: 29676652 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Abstract It is a great challenge to develop multifunctional nanocarriers for cancer diagnosis and therapy. Herein, versatile CDs/ICG-uLDHs nanovehicles for triple-modal fluorescence/photoacoustic/two-photon bioimaging and effective photothermal therapy were prepared via a facile self-assembly of red emission carbon dots (CDs), indocyanine green (ICG) with the ultrathin layered double hydroxides (uLDHs). Due to the J-aggregates of ICG constructed in the self-assembly process, CDs/ICG-uLDHs was able to stabilize the photothermal agent ICG and enhanced its photothermal efficiency. Furthermore, the unique confinement ...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
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